Compounds > sk&f 75670

Page last updated: 2024-09-05

sk&f 75670 and sk&f-38393

sk&f 75670 has been researched along with sk&f-38393 in 16 studies

Compound Research Comparison

Studies (sk&f 75670)	Trials (sk&f 75670)	Recent Studies (post-2010) (sk&f 75670)	Studies (sk&f-38393)	Trials (sk&f-38393)	Recent Studies (post-2010) (sk&f-38393)
9	0	5	2,012	29	242
24	0	1	2,012	29	242

Protein Interaction Comparison

Protein	Taxonomy	sk&f 75670 (IC50)	sk&f-38393 (IC50)
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2		2.8
D	Rattus norvegicus (Norway rat)		0.19

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (25.00)	18.7374
1990's	6 (37.50)	18.2507
2000's	4 (25.00)	29.6817
2010's	1 (6.25)	24.3611
2020's	1 (6.25)	2.80

Authors

Authors	Studies
Cheng, J; McCorvy, JD; Tan, L; Yan, W	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Glavin, GB	1
Bergman, J; Rosenzweig-Lipson, S	2
Gerlach, J; Lublin, H; Peacock, L	1
de Beltrán, KK; Kobayashi, M; Koshikawa, N; Omiya, K; Tomiyama, K	1
Weiss, B; Winkler, JD	1
Cooper, SJ; Rusk, IN	1
Arnt, J; Hyttel, J	1
Andersen, PH; Hohlweg, R; Jansen, JA; Nielsen, EB; Scheel-Krüger, J	1
Alam, AM; Starr, MS	1
Desai, RI; Katz, JL; Terry, P	2
Alberts, I; Giri, R; Harding, WW	1

Reviews

1 review(s) available for sk&f 75670 and sk&f-38393

Article	Year
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential. Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22 Topics: Animals; Drug Discovery; Humans; Ligands; Receptors, G-Protein-Coupled; Signal Transduction; Structure-Activity Relationship	2018

Other Studies

15 other study(ies) available for sk&f 75670 and sk&f-38393

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Central dopamine involvement in experimental gastrointestinal injury. Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dopamine; Dopamine Agents; Ligands; Male; Peptic Ulcer; Rats; Rats, Inbred Strains; Stress, Psychological	1992
Cocaine-antagonist effects of limited-efficacy D1 agonists. NIDA research monograph, 1992, Volume: 119 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cocaine; Conditioning, Operant; Dopamine Agents; Dopamine Antagonists; Receptors, Dopamine D1; Reinforcement Schedule; Saimiri	1992
Effect of D1 and D2 agonists in primates withdrawn from long-term treatment with haloperidol: the potential role of dopamine D1 receptors in dyskinesia. Clinical neuropharmacology, 1992, Volume: 15, Issue:6 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Cebus; Dopamine Agents; Dyskinesia, Drug-Induced; Ergolines; Female; Grooming; Haloperidol; Hypnotics and Sedatives; Male; Motor Activity; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome	1992
Dopamine D-1 but not D-2 receptor stimulation of the dorsal striatum potentiates apomorphine-induced jaw movements in rats. European journal of pharmacology, 1990, Mar-20, Volume: 178, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Corpus Striatum; Dopamine Agents; Dopamine Antagonists; Injections; Jaw; Male; Movement; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride	1990
Effect of continuous exposure to selective D1 and D2 dopaminergic agonists on rotational behavior in supersensitive mice. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; Dopamine Agents; Ergolines; Fenoldopam; Indoles; Male; Mice; Phenanthridines; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Tetrahydronaphthalenes; Thiophenes	1989
The selective dopamine D1 receptor agonist SK&F 38393: its effects on palatability- and deprivation-induced feeding, and operant responding for food. Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:1 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Conditioning, Operant; Dopamine Agents; Dose-Response Relationship, Drug; Drinking Behavior; Drug Interactions; Feeding Behavior; Fenoldopam; Food Deprivation; Male; Mice; Rats; Stereoisomerism; Tetrahydronaphthalenes; Thiophenes	1989
Behavioural differentiation between effects elicited at dopamine D-1 and D-2 receptors in rats. Clinical neuropharmacology, 1986, Volume: 9 Suppl 4 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; Discrimination, Psychological; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior	1986
Thienopyridine derivatives identified as the first selective, full efficacy, dopamine D1 receptor agonists. European journal of pharmacology, 1987, Jun-04, Volume: 137, Issue:2-3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Appetite Depressants; Benzazepines; Catalepsy; Discrimination, Psychological; Dopamine; Grooming; Motor Activity; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Thiophenes	1987
D1 agonists suppress zero Mg(2+)-induced epileptiform activity in the rat cingulate cortex slice. Neuroreport, 1993, Oct-25, Volume: 5, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cerebral Cortex; Colforsin; Dopamine; Dopamine Agents; Epilepsy; Female; Fenoldopam; In Vitro Techniques; Magnesium; Male; Propranolol; Rats; Rats, Wistar; Receptors, Dopamine D1	1993
Catalepsy-associated behavior induced by dopamine D1 receptor antagonists and partial dopamine D1 receptor agonists in squirrel monkeys. European journal of pharmacology, 1994, Aug-01, Volume: 260, Issue:2-3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Catalepsy; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Isoquinolines; Male; Receptors, Dopamine D1; Saimiri; Tetrahydroisoquinolines	1994
Comparison of the discriminative-stimulus effects of SKF 38393 with those of other dopamine receptor agonists. Behavioural pharmacology, 2003, Volume: 14, Issue:3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Benzazepines; Cocaine; Discrimination Learning; Discrimination, Psychological; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Humans; Male; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2	2003
A comparison of the locomotor stimulant effects of D1-like receptor agonists in mice. Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:4 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Benzazepines; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hydrolysis; Male; Mice; Motor Activity; Phosphatidylinositols; Receptors, Dopamine D1; Time Factors	2005
Synthesis, pharmacological evaluations, and molecular docking studies on a new 1,3,4,11b-tetrahydro-1H-fluoreno[9,1-cd]azepine framework: Rigidification of D Chemical biology & drug design, 2020, Volume: 96, Issue:2 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Azepines; Benzazepines; Dopamine Agonists; Hydrogen Bonding; Ligands; Molecular Conformation; Molecular Docking Simulation; Protein Binding; Receptors, Dopamine D1; Receptors, Serotonin; Structure-Activity Relationship	2020