sk&f-38393 has been researched along with oxidopamine in 182 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (18.13) | 18.7374 |
| 1990's | 105 (57.69) | 18.2507 |
| 2000's | 31 (17.03) | 29.6817 |
| 2010's | 12 (6.59) | 24.3611 |
| 2020's | 1 (0.55) | 2.80 |
| Authors | Studies |
|---|---|
| Pollack, AE; Wooten, GF | 1 |
| Ding, XZ; Mocchetti, I | 1 |
| Jenner, P; Marsden, CD; Rose, S; Thomas, KL | 1 |
| Breese, GR; Criswell, HE; Jensen, KF; Johnson, KB; Mueller, RA; Simson, PE | 1 |
| Boldry, RC; Chase, TN; Engber, TM; Kuo, S | 1 |
| Anderson, JJ; Chase, TN; Engber, TM | 1 |
| David, JC; Graybiel, AM; Paul, ML; Robertson, HA | 1 |
| LaHoste, GJ; Marshall, JF | 1 |
| Breese, GR; Criswell, HE; Duncan, GE; Johnson, KB; Jurevics, HA; Mueller, RA; Napier, TC; Simson, PE | 1 |
| Britton, DR; DeNinno, MP; Jenner, P; Kebabian, JW; Perner, R; Schoenleber, R; Smith, L; Williams, M | 1 |
| Di Chiara, G; Fenu, S; Morelli, M | 1 |
| Hiyama, Y; Matsuda, H; Matsumoto, K; Terasawa, K; Watanabe, H | 1 |
| Aceves, J; Benitez, J; Floran, B; Flores, G; Martinez-Fong, D; Sierra, A | 1 |
| Di Chiara, G; Morelli, M; Orzi, F; Pontieri, FE; Terenzi, R | 1 |
| Hu, XT; White, FJ | 1 |
| Fuller, RW; Gong, L; Kostrzewa, RM; Perry, KW | 2 |
| Fine, A; Robertson, GS; Robertson, HA | 1 |
| Collier, TJ; Sladek, JR; Steece-Collier, K; Yurek, DM | 1 |
| Britton, DR; Curzon, P; Kebabian, JW | 1 |
| Gong, L; Kostrzewa, RM | 1 |
| Bickford-Wimer, P; Strömberg, I | 1 |
| Jiang, HK; Wang, JY | 1 |
| Silverman, PB | 2 |
| Fukuda, H; Ito, H; Ono, H | 1 |
| Joyce, JN; Neal, BS | 1 |
| Hamdi, A; Kostrzewa, RM | 1 |
| Hong, JS; Jiang, HK; McGinty, JF | 1 |
| Breese, GR; Criswell, HE; Iorio, LC; McQuade, RD; Mueller, RA | 1 |
| Di Chiara, G; Morelli, M | 3 |
| Bennett, JP; Broaddus, WC | 1 |
| De Montis, G; Di Chiara, G; Morelli, M | 1 |
| Chase, TN; Engber, TM; Susel, Z; Walters, JR; Weick, BG | 1 |
| Fibiger, HC; Robertson, GS; Vincent, SR | 1 |
| Chase, TN; Engber, TM; Gerfen, CR; Mahan, LC; Monsma, FJ; Sibley, DR; Susel, Z | 1 |
| Baldessarini, RJ; Faedda, G; Gallitano, A; Gelbard, HA; Marsh, ER; Teicher, MH; Zorc, J | 1 |
| Breese, GR; Criswell, HE; Mueller, RA | 1 |
| Breese, GA; Criswell, HE; Mueller, RA | 1 |
| Feletou, M; Vanhoutte, PM | 1 |
| Breese, GR; Criswell, H; Mueller, RA | 1 |
| Arnt, J; Hyttel, J | 4 |
| Murphy, K; Peterson, MR; Robertson, GS; Robertson, HA | 1 |
| Boggan, WO; Faught, K; Middaugh, LD | 1 |
| Fletcher, GH; Starr, MS | 4 |
| Chase, TN; Engber, TM; Juncos, JL; Susel, Z | 1 |
| Breese, GR; Criswell, HE; Joh, TH; Lauder, JM; Maynard, EH; Mueller, RA; Towle, AC | 1 |
| Breese, GR; Mueller, RA | 1 |
| Breese, GR; Hong, JS; Krause, JE; Mueller, RA; Napier, TC; Sivam, SP | 1 |
| Goodale, DB; Jacobi, AG; Seyfried, DM; Weiss, B | 1 |
| Arnt, J | 3 |
| Breese, GR; Duncan, GE; Mueller, RA; Napier, TC | 1 |
| Walters, JR; Weick, BG | 2 |
| Starr, M | 1 |
| Bédard, P; Di Paolo, T; Falardeau, P; Rouillard, C | 1 |
| Bondy, SC; Breese, GR; Duncan, GE; Iorio, LC; Mueller, RA; Napier, TC | 1 |
| Trugman, JM; Wooten, GF | 1 |
| Callison, K; Cass, SA; Weiss, B; Winkler, JD | 1 |
| Breese, GR; Mueller, RA; Napier, TC | 1 |
| Baumeister, A; Breese, GR; Frye, GD; Mueller, RA; Napier, TC | 1 |
| Fenton, HM; Gerhardt, S; Leszczak, E; Liebman, JM | 1 |
| Arnt, J; Bøgesø, KP; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H | 1 |
| Currie, RW; Paul, ML; Robertson, HA | 1 |
| Brus, R; Kalbfleisch, JH; Kostrzewa, RM; Plech, A | 1 |
| Gancher, S; Mayer, A | 1 |
| Bruno, JP; Johnson, BJ | 1 |
| Carey, RJ; Fornaguera, J; Huston, JP; Schwarting, RK | 1 |
| Bentlage, C; Björklund, A; Nikkhah, G; Olsson, M | 1 |
| Carta, A; Fenu, S; Morelli, M | 2 |
| Thompson, LA; Twery, MJ; Walters, JR | 1 |
| Barone, P; Campanella, G; Cicarelli, G; Di Chiara, G; Morelli, M; Popoli, M | 2 |
| Boldry, RC; Chase, TN; Engber, TM | 1 |
| Di Chiara, G; Fenu, S; Morelli, M; Pinna, A | 1 |
| Cole, BN; LaHoste, GJ; Marshall, JF | 1 |
| Huang, NY; Kostrzewa, RM | 1 |
| Anderson, JJ; Chase, TN; Engber, TM; Kuo, S | 1 |
| Abrams, D; Bruno, JP; Byrnes, EM | 1 |
| Bronstein, DM; Hong, JS; Hudson, PM; Pennypacker, KR; Ye, H | 1 |
| Gong, L; Kostrzewa, RM; Li, C | 1 |
| Misu, Y; Okumura, F; Sato, K; Ueda, H | 1 |
| Cole, DG; Hyman, SE; Kobierski, LA; Konradi, C | 1 |
| Huang, KX; Walters, JR | 2 |
| Weiss, B; Zhang, SP; Zhou, LW | 1 |
| Breese, GR; Eckerman, DA; Moy, SS | 1 |
| Frankenschmidt, A; Rump, LC; Schaible, U; Schollmeyer, PJ; Schuster, MJ; Schwertfeger, E | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB; Sancesario, G | 1 |
| Carta, A; Cozzolino, A; Di Chiara, G; Fenu, S; Morelli, M; Pinna, A | 1 |
| Di Chiara, G; Linfante, I; Morelli, M; Orzi, F; Pontieri, FE | 1 |
| Anderson, JJ; Boldry, RC; Chase, TN; Engber, TM; Kuo, S | 1 |
| Chase, TN; Engber, TM; Marin, C; Susel, Z | 1 |
| Dollison, A; Espinosa, A; Ferreira, M; Jackson-Lewis, V; Jiang, H; Muthane, U; Parsons, B; Przedborski, S | 1 |
| Björklund, A; Duan, WM; Jödicke, A; Knappe, U; Nikkhah, G | 1 |
| Brus, R; Fuller, RW; Kostrzewa, RM; Perry, KW | 2 |
| Brus, R; Fuller, RW; Gong, L; Kostrzewa, RM; Perry, KW | 1 |
| Kostrzewa, RM; Neely, D | 1 |
| Florijn, WJ; Gispen, WH; Mulder, AH; Versteeg, DH | 1 |
| Qin, ZH; Weiss, B; Zhang, SP; Zhou, LW | 1 |
| Boldry, RC; Chase, TN; Kask, AM; Papa, SM | 1 |
| Laprade, N; Radja, F; Reader, TA; Soghomonian, JJ | 1 |
| di Chiara, G; Morelli, M; Pinna, A; Wardas, J | 1 |
| Jin, GZ; Sun, BC; Zhang, XX | 1 |
| Akkal, D; Audin, J; Bioulac, B; Burbaud, P | 1 |
| Carta, A; Di Chiara, G; Fenu, S; Morelli, M | 1 |
| Ferré, S; Fuxe, K; Giménez-Llort, L; Martínez, E; Pezzola, A; Popoli, P; Reggio, R | 1 |
| Fink, JS; Pollack, AE | 1 |
| Ibata, Y; Murakami, T; Nakamura, T; Okamura, H; Yokoyama, C | 1 |
| Barlas, C; Chugh, A; Johnson, RL; Marcotte, ER; Mishra, RK; Whan, D | 1 |
| Crocker, SJ; Morelli, M; Nakabeppu, Y; Robertson, GS; Wigle, N | 1 |
| Barone, P; DiChiara, G; Morelli, M; Pellecchia, MT; Vallone, D; Verde, P | 1 |
| Brus, R; Kostrzewa, RM; Nowak, P; Szkilnik, R | 1 |
| Joyce, JN; Neal-Beliveau, BS | 1 |
| Bruno, JP; Laprade, N; Sandstrom, M; Soghomonian, JJ | 1 |
| Bergstrom, DA; Huang, KX; Ruskin, DN; Walters, JR | 1 |
| Jin, GZ; Zhang, XX; Zhu, ZT | 1 |
| Drukarch, B; Stoof, JC; van de Witte, SV; Voorn, P | 1 |
| Di Chiara, G; Pinna, A | 1 |
| Bymaster, FP; Calligaro, DO; Delapp, NW; Fink-Jensen, A; Jeppesen, L; Kristensen, P; Rasmusseen, T; Sauerberg, P; Shannon, HE; Sheardown, MJ; Thomsen, C; Ward, JS; Whitesitt, C | 1 |
| Chase, TN; Oh, JD; Vaughan, CL | 1 |
| Herrera-Marschitz, M; Hökfelt, T; Koistinaho, J; Rodríguez-Puertas, R | 1 |
| Consolo, S; Di Chiara, G; Giorgi, S; Morelli, M; Rimoldi, M | 1 |
| Guo, X; Jin, GZ; Jin, J; Liu, J; Wang, BC; Zou, LL | 1 |
| Gresch, PJ; Walker, PD | 1 |
| Pollack, AE; Yates, TM | 1 |
| Belforte, JE; Murer, MG; Pazo, JH; Riquelme, LA; Tseng, KY | 1 |
| Cai, G; Friedman, E; Uryu, K; Zhen, X | 1 |
| Barbanoj, M; Casas, M; Jané, F; Prat, G; Rubio, A | 1 |
| Barbanoj, M; Casas, M; Jané, F; Kulisevsky, J; Prat, G; Robledo, P | 1 |
| Drukarch, B; Groenewegen, HJ; van de Witte, SV; Voorn, P | 1 |
| Fu, Y; Hu, GY; Jin, GZ; Liu, J; Zhang, XX | 1 |
| Breese, GR; Knapp, DJ; Moy, SS | 1 |
| Benabid, AL; Benazzouz, A; Bouali-Benazzouz, R; Gao, D; Ni, Z | 1 |
| Ferré, S; Fuxe, K; Pèzzola, A; Pintor, A; Popoli, P; Reggio, R; Scarchilli, L; Torvinen, M | 1 |
| Groenewegen, HJ; Van De Witte, SV; Voorn, P | 1 |
| Breese, GR; Moy, SS | 1 |
| Carta, AR; Morelli, M; Schibaev, NV; Vorobyov, VV | 1 |
| Liang, PJ; Liu, Y; Luo, FJ | 1 |
| Chancellor, MB; De Groat, WC; Kuno, S; Seki, S; Yoshimura, N | 1 |
| Brus, R; Kostrzewa, JP; Kostrzewa, RM; Nowak, P; Perry, KW | 1 |
| Battaglia, G; Heidenreich, BA; Mitrovic, I; Napier, TC | 1 |
| Blake, BL; Breese, GR; Knapp, DJ; Papadeas, ST | 1 |
| Chesselet, MF; Mehta, A; Menalled, L | 1 |
| Friedman, E; Goswami, S; Zhen, X | 1 |
| Cauli, O; Morelli, M; Pinna, A | 1 |
| Osborn, CV; Wirtshafter, D | 1 |
| Canlon, B; Niu, X | 1 |
| Cox, J; Sivam, SP | 1 |
| Biedka, I; Bortel, A; Brus, R; Dabrowska, J; Kostrzewa, RM; Nowak, P; Szczerbak, G; Słomian, G | 1 |
| Chen, J; Ma, L; Wang, F; Zhang, H; Zhen, X | 1 |
| Fukakusa, A; Hayase, M; Ito, M; Kim, HC; Kumagai, N; Mizoguchi, H; Nabeshima, T; Nagai, T; Otsuka, N; Sato, K; Takuma, K; Yamada, K | 1 |
| Annalisa, P; Carta, AR; Frau, L; Lucia, F; Micaela, M; Morelli, M; Nicola, S; Nicoletta, S; Pinna, A; Pontis, S; Schintu, N; Silvia, P; Simola, N | 1 |
| Blake, BL; Breese, GR; Halloran, C; McCown, TJ; Papadeas, ST | 1 |
| Daniels, WM; Di Chiara, G; Morelli, M; Schallert, T; Simola, N | 1 |
| Ballion, B; Chetrit, J; Frenois, F; Gonon, F; Murer, MG; Zold, CL | 1 |
| Cenci, MA; Lindgren, HS; Ohlin, KE | 1 |
| Pollack, AE; Thomas, LI | 1 |
| El Massioui, N; Faure, A; Leblanc-Veyrac, P | 1 |
| Carta, AR; Frau, L; Morelli, M; Pinna, A | 1 |
| Dimitrov, KD; Drake, JD; Kibuuka, LN; Pollack, AE | 1 |
| Frau, L; Morelli, M; Simola, N | 1 |
| Caramés, JM; Moratalla, R; Murer, MG; Solís, JM; Solís, O; Suárez, LM; Taravini, IR | 1 |
| Berretta, N; Bonito-Oliva, A; Castelli, V; Fisone, G; Giorgi, M; Ledonne, A; Mango, D; Mercuri, NB; Nisticò, R; Sancesario, G | 1 |
| Canela, EI; Canet-Pons, J; Casadó, V; Cortés, A; Dopeso-Reyes, IG; Farré, D; Franco, R; Labandeira-García, JL; Lanciego, JL; Lluís, C; Mallol, J; Moreno, E; Muñoz, A; Navarro, G; Reyes-Resina, I; Rico, AJ | 1 |
| Ashihara, E; Inden, M; Kitamura, Y; Shimohama, S; Takata, K; Tooyama, I; Yanagisawa, D | 1 |
| Lin, JY; Liu, ZG; Wang, MH; Wang, XJ; Xie, CL; Zhang, SF; Zhang, Y | 1 |
| Arcuri, L; Brambilla, R; Fasano, S; Frassineti, M; Journigan, BV; Mercatelli, D; Meyer, ME; Morari, M; Morella, I; Novello, S; Pisanò, CA; Polgar, WE; Zaveri, NT | 1 |
| Deshpande, P; Gu, W; Lester, HA; Wu, H; Xiao, C; Yan, X; Zhou, C | 1 |
| Abbaszadeh, M; Andreoli, L; Cao, X; Cenci, MA | 1 |
1 review(s) available for sk&f-38393 and oxidopamine
| Article | Year |
|---|---|
Neurobiology of D1 dopamine receptors after neonatal-6-OHDA treatment: relevance to Lesch-Nyhan disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Brain; Dopamine; Ergolines; Hydroxydopamines; Lesch-Nyhan Syndrome; Nerve Crush; Neurons; Oxidopamine; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D1; Self Mutilation | 1986 |
181 other study(ies) available for sk&f-38393 and oxidopamine
| Article | Year |
|---|---|
Differential regulation of striatal preproenkephalin mRNA by D1 and D2 dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Blotting, Northern; Corpus Striatum; Desipramine; Dopamine; Enkephalins; Ergolines; Gene Expression Regulation; Kinetics; Male; Nucleic Acid Hybridization; Oligonucleotide Probes; Oxidopamine; Protein Precursors; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; RNA, Messenger; Salicylamides; Stereotaxic Techniques | 1992 |
Dopaminergic regulation of cholecystokinin mRNA content in rat striatum.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benztropine; Blotting, Northern; Brain; Cerebral Cortex; Cholecystokinin; Cocaine; Corpus Striatum; Dopamine; Haloperidol; Kinetics; Male; Mesencephalon; Organ Specificity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; RNA, Messenger | 1992 |
Dissociation of the striatal D-2 dopamine receptor from adenylyl cyclase following 6-hydroxydopamine-induced denervation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Benzazepines; Corpus Striatum; Cyclic AMP; Denervation; Dopamine; Ergolines; Female; Homovanillic Acid; Oxidopamine; Prosencephalon; Quinpirole; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone | 1992 |
Comparison of the D1-dopamine agonists SKF-38393 and A-68930 in neonatal 6-hydroxydopamine-lesioned rats: behavioral effects and induction of c-fos-like immunoreactivity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Brain Chemistry; Chromans; Dopamine Agents; Dose-Response Relationship, Drug; Female; Motor Activity; Oxidopamine; Proto-Oncogene Proteins c-fos; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior | 1992 |
Dopaminergic modulation of striatal neuropeptides: differential effects of D1 and D2 receptor stimulation on somatostatin, neuropeptide Y, neurotensin, dynorphin and enkephalin.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Denervation; Dopamine Agents; Dynorphins; Enkephalin, Methionine; Ergolines; Male; Neuropeptide Y; Neurotensin; Oxidopamine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; Somatostatin | 1992 |
Differential effect of subthalamic nucleus ablation on dopamine D1 and D2 agonist-induced rotation in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agents; Male; Neural Pathways; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Substantia Nigra; Thalamic Nuclei | 1992 |
D1-like and D2-like dopamine receptors synergistically activate rotation and c-fos expression in the dopamine-depleted striatum in a rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amino Acid Sequence; Animals; Behavior, Animal; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Ergolines; Male; Molecular Sequence Data; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1992 |
Dopamine supersensitivity and D1/D2 synergism are unrelated to changes in striatal receptor density.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Corpus Striatum; Dopamine; Dopamine Agents; Ergolines; Haloperidol; Male; Oxidopamine; Quinpirole; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Spiperone; Stereotyped Behavior; Time Factors; Tritium | 1992 |
Augmented sensitivity of D1-dopamine receptors in lateral but not medial striatum after 6-hydroxydopamine-induced lesions in the neonatal rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Animals, Newborn; Autoradiography; Corpus Striatum; Female; Guanosine Triphosphate; Levodopa; Nucleus Accumbens; Oxidopamine; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Tyrosine 3-Monooxygenase | 1992 |
A-77636: a potent and selective dopamine D1 receptor agonist with antiparkinsonian activity in marmosets.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adamantane; Administration, Oral; Animals; Antiparkinson Agents; Benzazepines; Benzopyrans; Binding Sites; Callithrix; Cell Line; Dopamine Agents; Fishes; Injections, Subcutaneous; Mice; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Rats; Receptors, Dopamine D1 | 1992 |
Blockade of N-methyl-D-aspartate receptors potentiates dopaminergic responses in the 6-OHDA model of Parkinson: differential role of D-1 and D-2 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Caudate Nucleus; Dizocilpine Maleate; Dopamine; Drug Synergism; Levodopa; Male; Oxidopamine; Parkinson Disease, Secondary; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1992 |
Enhancement of rotational behavior induced by repeated administration of SKF38393 in rats with unilateral nigrostriatal 6-OHDA lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Antagonists; Male; Oxidopamine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra; Sulpiride | 1992 |
Activation of D1 receptors stimulates accumulation of gamma-aminobutyric acid in slices of the pars reticulata of 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine; gamma-Aminobutyric Acid; Male; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1; Substantia Nigra; Sympathectomy, Chemical | 1992 |
Metabolic mapping of the synergism between MK-801 and SKF 38393 in rats with unilateral lesions of the dopaminergic nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain; Corpus Striatum; Dizocilpine Maleate; Dopamine; Drug Synergism; Glucose; Male; Neural Pathways; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1992 |
Repeated D1 dopamine receptor agonist administration prevents the development of both D1 and D2 striatal receptor supersensitivity following denervation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Cerebral Ventricles; Corpus Striatum; Denervation; Desipramine; Dopamine; Electrophysiology; Ergolines; Injections, Intraventricular; Iontophoresis; Male; Membrane Potentials; Motor Activity; Multivariate Analysis; Neurons; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reference Values; Substantia Nigra | 1992 |
Supersensitization of the oral response to SKF 38393 in neonatal 6-OHDA-lesioned rats is mediated through a serotonin system.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Mastication; Oxidopamine; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin Antagonists | 1992 |
Dopaminergic grafts in the striatum reduce D1 but not D2 receptor-mediated rotation in 6-OHDA-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain Tissue Transplantation; Carbidopa; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Agents; Ergolines; Fetal Tissue Transplantation; Hydroxydopamines; Immunohistochemistry; Male; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
Chronic levodopa impairs the recovery of dopamine agonist-induced rotational behavior following neural grafting.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Brain Tissue Transplantation; Dopamine; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Fetal Tissue Transplantation; Levodopa; Male; Mesencephalon; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 1991 |
Rapid reversal of denervation supersensitivity of dopamine D1 receptors by l-dopa or a novel dopamine D1 receptor agonist, A68930.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Chromans; Denervation; Dopamine Agents; Levodopa; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1 | 1991 |
Supersensitized D1 receptors mediate enhanced oral activity after neonatal 6-OHDA.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Female; Mouth; Movement; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone | 1991 |
Effects of locally applied D1 and D2 agonists on striatal neurons with 6-OHDA and pertussis toxin lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Caudate Nucleus; Corpus Striatum; Dopamine Agents; Female; Nervous System Diseases; Neurons; Oxidopamine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotaxic Techniques; Sympathectomy, Chemical; Tetrahydronaphthalenes; Thiophenes; Up-Regulation; Virulence Factors, Bordetella | 1991 |
The effects of dopamine D-1 and D-2 receptor subtype agonists on nigrostriatal opioid dynorphin and enkephalin immunostaining in 6-hydroxydopamine lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agents; Dynorphins; Enkephalin, Methionine; Ergolines; Immunohistochemistry; Male; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra; Sympathectomy, Chemical | 1991 |
Sensitization and conditioned rotation: apomorphine, quinpirole and SKF-38393 compared.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Ergolines; Female; Motor Activity; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Substantia Nigra; Time Factors | 1991 |
2-phenylethylamine and methamphetamine enhance the spinal monosynaptic reflex by releasing noradrenaline from the terminals of descending fibers.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Blood Pressure; Hydroxydopamines; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Nerve Endings; Neurons; Norepinephrine; Oxidopamine; Phenethylamines; Prazosin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reflex, Monosynaptic; Reserpine; Spinal Cord | 1991 |
Dopamine D1 receptor behavioral responsitivity following selective lesions of the striatal patch compartment during development.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Autoradiography; Corpus Striatum; Haloperidol; Hydroxydopamines; Levodopa; Mazindol; Motor Activity; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Tritium | 1991 |
Ontogenic homologous supersensitization of dopamine D1 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Newborn; Corpus Striatum; Female; Injections, Intraventricular; Motor Activity; Oxidopamine; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior | 1991 |
Differential modulation of striatonigral dynorphin and enkephalin by dopamine receptor subtypes.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Corpus Striatum; Dynorphins; Enkephalins; Ergolines; Hydroxydopamines; Male; Oxidopamine; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Substantia Nigra | 1990 |
Pharmacological evaluation of SCH-12679: evidence for an in vivo antagonism of D1-dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aggression; Animals; Antipsychotic Agents; Avoidance Learning; Benzazepines; Dopamine Antagonists; Female; Hydroxydopamines; Levodopa; Oxidopamine; Pregnancy; Raclopride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 1990 |
MK-801 potentiates dopaminergic D1 but reduces D2 responses in the 6-hydroxydopamine model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benserazide; Dizocilpine Maleate; Dopamine Agents; Ergolines; Hydroxydopamines; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Stereotyped Behavior | 1990 |
Postnatal development of striatal dopamine function. II. Effects of neonatal 6-hydroxydopamine treatments on D1 and D2 receptors, adenylate cyclase activity and presynaptic dopamine function.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Benzazepines; Corpus Striatum; Dopamine; Hydroxydopamines; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1990 |
Changes in the D1 receptor-adenylate cyclase complex after priming.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Autoradiography; Corpus Striatum; Hydroxydopamines; In Vitro Techniques; Kinetics; Male; Membranes; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sympathectomy, Chemical | 1990 |
Responses of substantia nigra pars reticulata neurons to GABA and SKF 38393 in 6-hydroxydopamine-lesioned rats are differentially affected by continuous and intermittent levodopa administration.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Electrophysiology; gamma-Aminobutyric Acid; Hydroxydopamines; Injections, Intravenous; Iontophoresis; Levodopa; Male; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Sympathectomy, Chemical | 1990 |
Striatonigral projection neurons contain D1 dopamine receptor-activated c-fos.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Hydroxydopamines; Male; Neurons; Oxidopamine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior; Substantia Nigra | 1990 |
D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cerebral Cortex; Corpus Striatum; Ergolines; Gene Expression Regulation; Globus Pallidus; Hydroxydopamines; Models, Neurological; Neurons; Oligonucleotide Probes; Oxidopamine; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger; Substantia Nigra; Thalamus | 1990 |
Dopamine D1 receptor development depends on endogenous dopamine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Brain; Dopamine; Female; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tritium | 1990 |
Stereospecific blockade of N-methyl-D-aspartate transmission by MK 801 prevents priming of SKF 38393-induced turning.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Aspartic Acid; Dibenzocycloheptenes; Dizocilpine Maleate; Hydroxydopamines; Male; N-Methylaspartate; Oxidopamine; Rats; Rats, Inbred Strains; Stereoisomerism; Stereotyped Behavior; Sympathectomy, Chemical; Synaptic Transmission | 1990 |
Long-term D1-dopamine receptor sensitization in neonatal 6-OHDA-lesioned rats is blocked by an NMDA antagonist.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hydroxydopamines; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Clozapine antagonism of D-1 and D-2 dopamine receptor-mediated behaviors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Appetite Depressants; Behavior, Animal; Benzazepines; Clozapine; Dibenzazepines; Ergolines; Female; Hydroxydopamines; Motor Activity; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Serotonin | 1989 |
Tetrodotoxin-insensitive relaxation of coronary arterial smooth muscle to electrical stimulation: possible involvement of a dopaminergic mechanism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Calcium; Cattle; Coronary Vessels; Dogs; Dopamine; Electric Stimulation; Female; Hydroxydopamines; In Vitro Techniques; Male; Oxidopamine; Receptors, Dopamine; Scorpion Venoms; Swine; Tetraethylammonium Compounds; Tetrodotoxin; Vasodilation | 1989 |
Priming of D1-dopamine receptor responses: long-lasting behavioral supersensitivity to a D1-dopamine agonist following repeated administration to neonatal 6-OHDA-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Dopamine; Environment; Female; Hydroxydopamines; Male; Microinjections; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Time Factors | 1989 |
Selective inactivation of dopamine D1 and D2 receptors in 6-hydroxydopamine-lesioned rats: evidence that the effect of D1 and D2 agonists can be expressed in the absence of the heterologous DA receptor.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; Dopamine Antagonists; Hydroxydopamines; Male; Oxidopamine; Pergolide; Quinolines; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1989 |
D1-dopamine receptor agonists selectively activate striatal c-fos independent of rotational behaviour.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Hydroxydopamines; Indoles; Male; Oxidopamine; Phenanthridines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Stereotyped Behavior | 1989 |
Effect of dopaminergic drugs on enhancement of the binding of quinuclidinyl benzilate by phencyclidine in vivo.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Atropine; Benzazepines; Dopamine; Dopamine Agents; Ergolines; Hydroxydopamines; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxidopamine; Phencyclidine; Quinpirole; Quinuclidines; Quinuclidinyl Benzilate | 1989 |
Differential effects of pallidal lesions on the behavioural responses to SKF 38393, LY 171555 and apomorphine in the rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Dopamine Agents; Ergolines; Globus Pallidus; Hydroxydopamines; Kainic Acid; Medial Forebrain Bundle; Oxidopamine; Quinpirole; Rats | 1989 |
Continuous and intermittent levodopa differentially affect rotation induced by D-1 and D-2 dopamine agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agents; Hydroxydopamines; Levodopa; Male; Motor Activity; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1989 |
Serotonergic innervation of the rat caudate following a neonatal 6-hydroxydopamine lesion: an anatomical, biochemical and pharmacological study.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Caudate Nucleus; Hydroxydopamines; Methysergide; Oxidopamine; Rats; Rats, Inbred Strains; Serotonin; Tyrosine 3-Monooxygenase | 1989 |
Differential involvement of dopamine D-1 and D-2 receptors in the circling behaviour induced by apomorphine, SK & F 38393, pergolide and LY 171555 in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Antiparkinson Agents; Antipsychotic Agents; Apomorphine; Appetite Depressants; Benzazepines; Electric Stimulation; Ergolines; Humans; Hydroxydopamines; Male; Oxidopamine; Pergolide; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Sympathectomy, Chemical; Time Factors | 1985 |
SCH-23390 antagonism of a D-2 dopamine agonist depends upon catecholaminergic neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Fibers; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Benzazepines; Ergolines; Hydroxydopamines; Male; Methyltyrosines; Motor Activity; Oxidopamine; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Reserpine | 1985 |
Neonatal and adult 6-hydroxydopamine-induced lesions differentially alter tachykinin and enkephalin gene expression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Animals, Newborn; Benzazepines; Corpus Striatum; Dopamine; Dynorphins; Enkephalin, Methionine; Enkephalins; Ergolines; Female; Gene Expression Regulation; Hippocampus; Hydroxydopamines; Male; Motor Activity; Neuropeptides; Oxidopamine; Peptide Fragments; Protein Precursors; Quinpirole; Rats; Rats, Inbred Strains; RNA, Messenger; Substantia Nigra; Tachykinins | 1987 |
Selective protection from the inhibition by EEDQ of D1 and D2 dopamine agonist-induced rotational behavior in mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Antagonists; Animals; Appetite Depressants; Benzazepines; Ergolines; Hydroxydopamines; Male; Mice; Mice, Inbred Strains; Motor Activity; Oxidopamine; Quinolines; Quinpirole; Receptors, Dopamine | 1988 |
Behavioural stimulation is induced by separate dopamine D-1 and D-2 receptor sites in reserpine-pretreated but not in normal rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Catalepsy; Ergolines; Hydroxydopamines; Ketanserin; Male; Motor Activity; Oxidopamine; Pergolide; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Stereotyped Behavior | 1985 |
Inhibition of SKF 38393- and pergolide-induced circling in rats with unilateral 6-OHDA lesion is correlated to dopamine D-1 and D-2 receptor affinities in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dopamine Antagonists; Drug Interactions; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Pergolide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1986 |
Effects of D1 and D2 dopamine receptor stimulation on the activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine lesioned rats: D1/D2 coactivation induces potentiated responses.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Apomorphine; Benzamides; Benzazepines; Dopamine; Dopamine Antagonists; Drug Interactions; Ergolines; Hydroxydopamines; Male; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra; Time Factors | 1987 |
Topography of dopamine behaviours mediated by D1 and D2 receptors revealed by intrastriatal injection of SKF 38393, lisuride and apomorphine in rats with a unilateral 6-hydroxydopamine-induced lesion.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Brain Mapping; Corpus Striatum; Female; Hydroxydopamines; Lisuride; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1987 |
D-1 dopamine receptor stimulation potentiates neurophysiological effects of bromocriptine in rats with lesions of the nigrostriatal dopamine pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Benzazepines; Bromocriptine; Corpus Striatum; Drug Synergism; Hydroxydopamines; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Substantia Nigra | 1987 |
Behavioural evidence for the functionality of D-2 but not D-1 dopamine receptors at multiple brain sites in the 6-hydroxydopamine-lesioned rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; Brain; Hydroxydopamines; Lisuride; Metoclopramide; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1987 |
Opposing roles of dopamine D1 and D2 receptors in nigral gamma-[3H]aminobutyric acid release?
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Benzazepines; Calcium; Dopamine; Dopamine Antagonists; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Oxidopamine; Potassium; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1987 |
Role of the substantia nigra in the expression of dopamine D1 receptor-mediated and D2 receptor-mediated behaviours.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Caudate Nucleus; Ergolines; Female; Hydroxydopamines; Injections, Subcutaneous; Kainic Acid; Microinjections; Oxidopamine; Phenethylamines; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Substantia Nigra; Time Factors | 1987 |
Repeated stimulation of D-1 dopamine receptors increases the circling response to bromocriptine in rats with a 6-OHDA lesion.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Appetite Depressants; Benzazepines; Bromocriptine; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Hydroxydopamines; Locomotion; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1988 |
6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Corpus Striatum; Dopamine; Dopamine Antagonists; Ergolines; Female; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Microinjections; Motor Activity; Nucleus Accumbens; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Septal Nuclei; Spiperone | 1987 |
Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Basal Ganglia; Behavior, Animal; Benzazepines; Deoxyglucose; Dose-Response Relationship, Drug; Ergolines; Glucose; Hydroxydopamines; Male; Oxidopamine; Quinpirole; Rats; Receptors, Dopamine; Substantia Nigra | 1987 |
Agonist-induced homologous and heterologous sensitization to D-1- and D-2-dependent contraversive turning.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Appetite Depressants; Benzazepines; Ergolines; Hydroxydopamines; Male; Oxidopamine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior | 1987 |
Selective down-regulation of D1 dopamine mediated rotational behavior in supersensitive mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Appetite Depressants; Benzazepines; Binding Sites; Dopamine; Ergolines; Hydroxydopamines; Male; Mice; Mice, Inbred Strains; Motor Activity; Oxidopamine; Quinpirole; Rats; Rotation | 1988 |
Differential effects of dopamine D-1 and D-2 agonists and antagonists in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Benzazepines; Brain; Ergolines; Humans; Hydroxydopamines; Oxidopamine; Pergolide; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1985 |
Dopamine agonist-induced locomotor activity in rats treated with 6-hydroxydopamine at differing ages: functional supersensitivity of D-1 dopamine receptors in neonatally lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Age Factors; Animals; Animals, Newborn; Apomorphine; Benzazepines; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Female; Flupenthixol; Haloperidol; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1985 |
Hyperactivity induced by stimulation of separate dopamine D-1 and D-2 receptors in rats with bilateral 6-OHDA lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzamides; Benzazepines; Clopenthixol; Dopamine; Dose-Response Relationship, Drug; Ergolines; Flupenthixol; Hydroxydopamines; Hypothalamus; Male; Motor Activity; Oxidopamine; Pergolide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone | 1985 |
Evidence that D-1 dopamine receptors contribute to the supersensitive behavioral responses induced by L-dihydroxyphenylalanine in rats treated neonatally with 6-hydroxydopamine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Dihydroxyphenylalanine; Drug Interactions; Ergolines; Female; Flupenthixol; Haloperidol; Hydroxydopamines; Levodopa; Male; Motor Activity; Oxidopamine; Pregnancy; Quinpirole; Rats; Receptors, Dopamine; Self Mutilation; Stereotyped Behavior | 1985 |
Differential inhibition by dopamine D-1 and D-2 antagonists of circling behaviour induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Antipsychotic Agents; Appetite Depressants; Benzamides; Benzazepines; Catalepsy; Clopenthixol; Ergolines; Flupenthixol; Humans; Hydroxydopamines; Male; Oxidopamine; Pergolide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1984 |
Evidence for heterogeneous rotational responsiveness to apomorphine, 3-PPP and SKF 38393 in 6-hydroxydopamine-denervated rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Clozapine; Ergolines; Humans; Hydroxydopamines; Male; Oxidopamine; Pergolide; Piperidines; Postural Balance; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Sympathectomy, Chemical | 1984 |
Enhanced D1 affinity in a series of piperazine ring substituted 1-piperazino-3-arylindans with potential atypical antipsychotic activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3T3 Cells; Adrenergic Agents; Adrenergic alpha-1 Receptor Antagonists; Animals; Antipsychotic Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Indans; Mice; Oxidopamine; Piperazines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin Antagonists; Structure-Activity Relationship | 1995 |
Priming of a D1 dopamine receptor behavioural response is dissociated from striatal immediate-early gene activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Apomorphine; Base Sequence; Behavior, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Ergolines; Genes, Immediate-Early; Immunohistochemistry; Male; Molecular Sequence Data; Neostriatum; Neural Pathways; Oxidopamine; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Rotation; Substantia Nigra | 1995 |
Enhanced oral activity responses to intrastriatal SKF 38393 and m-CPP are attenuated by intrastriatal mianserin in neonatal 6-OHDA-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Female; Mianserin; Motor Activity; Mouth; Oxidopamine; Piperazines; Rats; Rats, Inbred Strains; Serotonin Receptor Agonists | 1995 |
Sensitization to apomorphine-induced rotational behavior in 6-OHDA-lesioned rats: effects of NMDA antagonists on drug response.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; N-Methylaspartate; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Sympathectomy, Chemical | 1995 |
Dopaminergic modulation of striatal acetylcholine release in rats depleted of dopamine as neonates.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Benzamides; Benzazepines; Corpus Striatum; Dopamine Agonists; Ergolines; Humans; Infant, Newborn; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Stimulation of D1- or D2-receptors in drug-naive rats with different degrees of unilateral nigro-striatal dopamine lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Dopamine; Ergolines; Locomotion; Male; Nerve Degeneration; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra; Time Factors | 1995 |
Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphine; Brain Tissue Transplantation; Carbidopa; Dextroamphetamine; Disease Models, Animal; Dopamine; Dopamine Agonists; Ergolines; Female; Fetal Tissue Transplantation; Forelimb; Functional Laterality; Levodopa; Motor Activity; Movement Disorders; Norepinephrine; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra; Transplantation, Heterotopic | 1995 |
Modulation of dopamine D1-mediated turning behavior and striatal c-fos expression by the substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dizocilpine Maleate; Immunohistochemistry; Injections; Male; Neostriatum; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1995 |
Intracellularly recorded response of rat striatal neurons in vitro to fenoldopam and SKF 38393 following lesions of midbrain dopamine cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine; Dopamine Agonists; Drug Interactions; Electric Stimulation; Ergolines; Evoked Potentials; Fenoldopam; In Vitro Techniques; Male; Mesencephalon; Microelectrodes; Neostriatum; Neurons; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley | 1994 |
Behavioural sensitization in 6-hydroxydopamine lesioned rats involves the dopamine signal transduction: changes in DARPP-32 phosphorylation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Behavior, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Levodopa; Male; Nerve Tissue Proteins; Oxidopamine; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Signal Transduction; Sympathectomy, Chemical | 1994 |
On-off effects of dopamine receptor agonists in the hemi-parkinsonian rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Bromocriptine; Cocaine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Injections, Intraperitoneal; Motor Activity; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 1993 |
Influence of previous exposure to levodopa on the interaction between dizocilpine and dopamine D1 and D2 agonists in rats with 6-hydroxydopamine-induced lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Diseases; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Levodopa; Male; Motor Activity; N-Methylaspartate; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1993 |
Adenosine A2 receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Animals; Antihypertensive Agents; Autoradiography; Basal Ganglia; Benserazide; Binding Sites; Dopamine Agents; Ergolines; Levodopa; Male; Neural Pathways; Neurons; Oxidopamine; Phenethylamines; Quinolinic Acid; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Purinergic P1; Stereotyped Behavior | 1994 |
Dopamine D2 receptor control of pallidal fos expression: comparisons between intact and 6-hydroxydopamine-treated hemispheres.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Corpus Striatum; Dopamine Agents; Dopamine D2 Receptor Antagonists; Ergolines; Functional Laterality; Gene Expression; Genes, fos; Globus Pallidus; Male; Oxidopamine; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Substantia Nigra | 1993 |
Enhanced oral activity response to A77636 in neonatal 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adamantane; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Benzopyrans; Dopamine Agents; Female; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mouth; Oxidopamine; Pregnancy; Rats; Rats, Sprague-Dawley | 1994 |
Dopamine D1 receptor-stimulated release of acetylcholine in rat striatum is mediated indirectly by activation of striatal neurokinin1 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Androstanes; Animals; Benzimidazoles; Biphenyl Compounds; Corpus Striatum; Fenoldopam; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Neurokinin-1 | 1994 |
Co-activation of D1- and D2-like receptors is unnecessary for stimulated motor behavior in rats depleted of dopamine during development.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Brain; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Ergolines; Male; Motor Activity; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1994 |
Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Atropine; Base Sequence; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dynorphins; Ergolines; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Immediate-Early Proteins; Male; Molecular Sequence Data; Nerve Tissue Proteins; Oxidopamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1994 |
Neonatal 6-hydroxydopamine and adult SKF 38393 treatments alter dopamine D1 receptor mRNA levels: absence of other neurochemical associations with the enhanced behavioral responses of lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Benzazepines; Binding, Competitive; Brain; Cerebral Ventricles; Colforsin; Corpus Striatum; Dopamine; Gene Expression; Injections, Intraventricular; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; RNA, Messenger; Sodium Fluoride | 1994 |
Supersensitization of intrastriatal dopamine receptors involved in opposite regulation of acetylcholine release in Parkinson's model rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; Animals; Benzazepines; Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ergolines; Male; Microdialysis; Neostriatum; Neurons; Oxidopamine; Parkinson Disease, Secondary; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Sympathectomy, Chemical | 1994 |
6-Hydroxydopamine lesions of rat substantia nigra up-regulate dopamine-induced phosphorylation of the cAMP-response element-binding protein in striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dopamine; Embryo, Mammalian; Ergolines; Gene Expression; Genes, fos; Levodopa; Male; Neurons; Oxidopamine; Phosphorylation; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Substantia Nigra | 1994 |
Electrophysiological effects of SKF 38393 in rats with reserpine treatment and 6-hydroxydopamine-induced nigrostriatal lesions reveal two types of plasticity in D1 dopamine receptor modulation of basal ganglia output.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Basal Ganglia; Ergolines; Male; Neuronal Plasticity; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reserpine; Substantia Nigra | 1994 |
Oligodeoxynucleotide antisense to the D1 dopamine receptor mRNA inhibits D1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Base Sequence; Behavior, Animal; Corpus Striatum; Ergolines; Grooming; Male; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Oxidopamine; Oxotremorine; Quinpirole; Receptors, Dopamine D1; Rotation; Stereotyped Behavior | 1994 |
Altered activity patterns following neonatal 6-hydroxydopamine lesions to dopaminergic neurons: effect of SKF-38393.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Biogenic Monoamines; Dopamine; Habituation, Psychophysiologic; Handling, Psychological; Male; Motor Activity; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Reference Values | 1994 |
Dopamine DA2-receptor activation inhibits noradrenaline release in human kidney slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Brimonidine Tartrate; Calcium; Dopamine Agents; Ergolines; Fenoldopam; Humans; In Vitro Techniques; Indoles; Kidney Cortex; Middle Aged; Norepinephrine; Oxidopamine; Pyridines; Quinoxalines; Quinpirole; Receptors, Dopamine D2; Sulpiride; Tetrodotoxin | 1993 |
Electrophysiology of dopamine-denervated striatal neurons. Implications for Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Corpus Striatum; Denervation; Dopamine; Dopamine Agents; Ergolines; Male; Oxidopamine; Parkinson Disease, Secondary; Quinoxalines; Quinpirole; Rats; Rats, Wistar; Substantia Nigra; Synaptic Membranes; Tetrodotoxin | 1993 |
Blockade of muscarinic receptors potentiates D1 dependent turning behavior and c-fos expression in 6-hydroxydopamine-lesioned rats but does not influence D2 mediated responses.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Caudate Nucleus; Dopamine Agents; Ergolines; Gene Expression; Genes, fos; Immunohistochemistry; Male; Muscarinic Antagonists; Oxidopamine; Parasympathetic Nervous System; Putamen; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Scopolamine; Stereotyped Behavior; Synaptic Transmission | 1993 |
Local cerebral glucose utilization after D1 receptor stimulation in 6-OHDA lesioned rats: effect of sensitization (priming) with a dopaminergic agonist.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain; Deoxyglucose; Dopamine Agents; Ergolines; Glucose; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 1993 |
N-methyl-D-aspartate receptor blockade differentially modifies regional cerebral metabolic responses to D1 and D2 dopamine agonists in rats with a unilateral 6-hydroxydopamine lesion.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Chemistry; Corpus Striatum; Deoxyglucose; Dizocilpine Maleate; Dopamine Agents; Ergolines; Glucose; Male; Neural Pathways; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior; Substantia Nigra | 1993 |
Differential effects of chronic dopamine D1 and D2 receptor agonists on rotational behavior and dopamine receptor binding.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Autoradiography; Binding Sites; Corpus Striatum; Denervation; Dopamine Agents; Ergolines; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1993 |
Dose-related effects of a neonatal 6-OHDA lesion on SKF 38393- and m-chlorophenylpiperazine-induced oral activity responses of rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Biogenic Monoamines; Corpus Striatum; Dose-Response Relationship, Drug; Mouth; Movement; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 1993 |
Adenosine receptor antagonists potentiate dopamine receptor agonist-induced rotational behavior in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Bromocriptine; Male; Motor Activity; Oxidopamine; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Theobromine; Theophylline; Time Factors; Xanthines | 1993 |
Restoration of complex sensorimotor behavior and skilled forelimb use by a modified nigral cell suspension transplantation approach in the rat Parkinson model.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Caudate Nucleus; Corpus Striatum; Denervation; Dextroamphetamine; Dopamine; Ergolines; Feeding Behavior; Female; Fetal Tissue Transplantation; Forelimb; Motor Activity; Orientation; Oxidopamine; Parkinson Disease, Secondary; Putamen; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Regression Analysis; Rotation; Substantia Nigra | 1993 |
Supersensitization of the oral response to SKF 38393 in neonatal 6-hydroxydopamine-lesioned rats is eliminated by neonatal 5,7-dihydroxytryptamine treatment.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 5,7-Dihydroxytryptamine; Animals; Corpus Striatum; Female; Motor Activity; Mouth; Muscarinic Antagonists; Nerve Fibers; Oxidopamine; Pilocarpine; Piperazines; Pregnancy; Rats; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1994 |
Ontogenetic SKF 38393 treatments sensitize dopamine D1 receptors in neonatal 6-OHDA-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Corpus Striatum; Motor Activity; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereotyped Behavior | 1993 |
Age-dependence of a 6-hydroxydopamine lesion on SKF 38393- and m-chlorophenylpiperazine-induced oral activity responses of rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Biogenic Monoamines; Corpus Striatum; Female; Injections, Intraventricular; Male; Motor Activity; Mouth; Nerve Fibers; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 1993 |
Enhanced pilocarpine-induced oral activity responses in neonatal 6-OHDA treated rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; Female; Oxidopamine; Pilocarpine; Piperazines; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Serotonin Receptor Agonists | 1993 |
Adrenocorticotropin/alpha-melanocyte-stimulating hormone (ACTH/MSH)-like peptides modulate adenylate cyclase activity in rat brain slices: evidence for an ACTH/MSH receptor-coupled mechanism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Desipramine; Dopamine; Dose-Response Relationship, Drug; Ergolines; In Vitro Techniques; Kinetics; Male; Organ Specificity; Oxidopamine; Quinpirole; Rats; Rats, Wistar; Receptors, Corticotropin; Receptors, Pituitary Hormone; Sulpiride | 1993 |
Antisense oligodeoxynucleotide inhibits D2 dopamine receptor-mediated behavior and D2 messenger RNA.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Base Sequence; Corpus Striatum; DNA, Antisense; Dopamine Antagonists; Ergolines; Injections, Intraventricular; Male; Mice; Molecular Sequence Data; Motor Activity; Oligodeoxyribonucleotides; Oxidopamine; Oxotremorine; Quinpirole; Receptors, Dopamine; RNA, Messenger; Rotation | 1993 |
MK-801 reverses effects of chronic levodopa on D1 and D2 dopamine agonist-induced rotational behavior.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Ergolines; Excitatory Amino Acid Antagonists; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Sympatholytics | 1995 |
Dopamine receptor agonists regulate levels of the serotonin 5-HT2A receptor and its mRNA in a subpopulation of rat striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Amphetamines; Animals; Animals, Newborn; Apomorphine; Autoradiography; Binding, Competitive; Dopamine Agonists; Enkephalins; Female; In Situ Hybridization; Iodine Radioisotopes; Microinjections; Motor Activity; Neostriatum; Neurons; Oxidopamine; Pregnancy; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Serotonin; RNA, Messenger; Serotonin Receptor Agonists | 1996 |
Dopamine mediated responses in 6-hydroxydopamine lesioned rats involve changes of the signal transduction.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Evaluation Studies as Topic; Functional Laterality; Male; Nerve Tissue Proteins; Oxidopamine; Phosphoproteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Substantia Nigra | 1995 |
Blockade of A2a adenosine receptors positively modulates turning behaviour and c-Fos expression induced by D1 agonists in dopamine-denervated rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Denervation; Male; Motor Activity; Nerve Tissue Proteins; Oxidopamine; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Rotation; Triazoles; Xanthines | 1996 |
(-)-Stepholidine acts as a D1 partial agonist on firing activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Berberine; Dopamine Agonists; Electrophysiology; Haloperidol; Male; Membrane Potentials; Microelectrodes; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reserpine; Substantia Nigra | 1996 |
Responses of substantia nigra pars reticulata neurons to intrastriatal D1 and D2 dopaminergic agonist injections in the rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine Agonists; Electrophysiology; Male; Microinjections; Neostriatum; Neurons; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Substantia Nigra | 1996 |
Effect of MK 801 on priming of D1-dependent contralateral turning and its relationship to c-fos expression in the rat caudate-putamen.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Caudate Nucleus; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Immunohistochemistry; Male; N-Methylaspartate; Oxidopamine; Proto-Oncogene Proteins c-fos; Putamen; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics; Synaptic Transmission | 1996 |
Adenosine A1 receptor blockade selectively potentiates the motor effects induced by dopamine D1 receptor stimulation in rodents.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Locomotion; Male; Mice; Mice, Inbred Strains; Motor Activity; Motor Neurons; Oxidopamine; Purinergic P1 Receptor Antagonists; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reserpine; Sympatholytics; Theophylline | 1996 |
Dopaminergic regulation of AP-1 transcription factor DNA binding activity in rat striatum.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; DNA; Dopamine; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1; Transcription Factors | 1996 |
Synergistic interaction between an adenosine antagonist and a D1 dopamine agonist on rotational behavior and striatal c-Fos induction in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agonists; Drug Synergism; Functional Laterality; Male; Motor Activity; Neurotoxins; Oxidopamine; Proto-Oncogene Proteins c-fos; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Rotation; Theobromine | 1996 |
Self-injurious behavior and dopaminergic neuron system in neonatal 6-hydroxydopamine-lesioned rat: 2. Intracerebral microinjection of dopamine agonists and antagonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Brain; Caudate Nucleus; Dopamine Agonists; Dopamine Antagonists; Female; Functional Laterality; Levodopa; Microinjections; Neurons; Nucleus Accumbens; Oxidopamine; Pregnancy; Putamen; Rats; Rats, Wistar; Self Mutilation; Substantia Nigra | 1997 |
Modulation of dopamine receptor agonist-induced rotational behavior in 6-OHDA-lesioned rats by a peptidomimetic analogue of Pro-Leu-Gly-NH2 (PLG).
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Brain; Dopamine; Dopamine Agonists; Drug Synergism; Levodopa; Male; MSH Release-Inhibiting Hormone; Oxidopamine; Pyrrolidinones; Quinpirole; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1997 |
D1-Receptor-related priming is attenuated by antisense-meditated 'knockdown' of fosB expression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Corpus Striatum; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, Immediate-Early; Immediate-Early Proteins; Male; Motor Activity; Oligonucleotides, Antisense; Oxidopamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; Receptors, Dopamine D1; Stereotyped Behavior; Transcription Factors; Transcription, Genetic | 1998 |
Behavioural sensitization in 6-hydroxydopamine-lesioned rats is related to compositional changes of the AP-1 transcription factor: evidence for induction of FosB- and JunD-related proteins.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benserazide; Cell Nucleus; Corpus Striatum; Denervation; Dizocilpine Maleate; Gene Expression Regulation; Levodopa; Male; Motor Activity; Neurons; Oxidopamine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Rotation; Stereotyped Behavior; Transcription Factor AP-1 | 1997 |
Nitro-l-arginine attenuates SKF 38393-induced oral activity in neonatal 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Catalepsy; Dopamine Agonists; Drug Interactions; Enzyme Inhibitors; Female; Male; NG-Nitroarginine Methyl Ester; Nitroarginine; Oxidopamine; Rats; Rats, Wistar; Sympatholytics; Yawning | 1997 |
Behavioral responsitivity to dopamine receptor agonists after extensive striatal dopamine lesions during development.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Corpus Striatum; Critical Period, Psychological; Dopamine; Dopamine Agonists; Dyskinesia, Drug-Induced; Female; Grooming; Male; Motor Activity; Mouth; Observation; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Self-Injurious Behavior; Stereotyped Behavior | 1998 |
c-fos gene expression is induced in a subpopulation of striatal neurons following a single administration of a dopamine D1-receptor agonist in adult rats lesioned with 6-OHDA as neonates.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Corpus Striatum; Dopamine Agonists; Female; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Neurons; Oxidopamine; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger; Sympatholytics | 1998 |
N-methyl-D-aspartate receptor blockade attenuates D1 dopamine receptor modulation of neuronal activity in rat substantia nigra.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Corpus Striatum; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Reserpine; Stereotaxic Techniques; Substantia Nigra | 1998 |
Comparison of (-)-stepholidine and D1 or D2 agonists on unit firing of globus pallidus in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Berberine; Calcium Channel Blockers; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Globus Pallidus; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1998 |
Priming with L-DOPA differently affects dynorphin and substance P mRNA levels in the striatum of 6-hydroxydopamine-lesioned rats after challenge with dopamine D1-receptor agonist.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Brain; Corpus Striatum; Dynorphins; Injections, Intraperitoneal; Injections, Subcutaneous; Levodopa; Male; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1; RNA, Messenger; Stereotaxic Techniques; Substance P | 1998 |
Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW 373U86 and SNC 80: 3. Facilitation of D1 and D2 responses in unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzamides; Brain Chemistry; Conditioning, Operant; Dopamine; Dopamine Agonists; Immunohistochemistry; Male; Microdialysis; Oxidopamine; Piperazines; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Sympathectomy, Chemical | 1998 |
Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antibodies; Antipsychotic Agents; Brain Chemistry; Bridged Bicyclo Compounds; Cholinergic Fibers; Dopamine; Dopamine Agonists; Dopamine Antagonists; Male; Muscarinic Agonists; Oxidopamine; Oxotremorine; Parasympathomimetics; Pilocarpine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Substantia Nigra; Succinimides; Sympatholytics; Thiadiazoles | 1998 |
Effect of dopamine denervation and dopamine agonist administration on serine phosphorylation of striatal NMDA receptor subunits.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antibodies; Antiparkinson Agents; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Corpus Striatum; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Levodopa; Male; Motor Neurons; Nerve Degeneration; Oxidopamine; Parkinson Disease, Secondary; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Sulfonamides; Sympatholytics | 1999 |
Dopamine D1 receptor modulation of glutamate receptor messenger RNA levels in the neocortex and neostriatum of unilaterally 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine; Dopamine Agonists; Drug Design; Gene Expression Regulation; Glutamic Acid; In Situ Hybridization; Male; Motor Activity; Neocortex; Nerve Tissue Proteins; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; RNA, Messenger; Schizophrenia; Stereotyped Behavior; Sympatholytics; Tegmentum Mesencephali | 1999 |
Increased striatal expression of glutamate decarboxylase 67 after priming of 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Functional Laterality; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Isoenzymes; Levodopa; Male; Motor Activity; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger; Time Factors; Transcription, Genetic | 1999 |
Enhancement of (-)-stepholidine on protein phosphorylation of a dopamine- and cAMP-regulated phosphoprotein in denervated striatum of oxidopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Berberine; Corpus Striatum; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Enzyme Inhibitors; Male; Nerve Tissue Proteins; Oxidopamine; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley | 1998 |
Synergistic interaction between serotonin-2 receptor and dopamine D1 receptor stimulation on striatal preprotachykinin mRNA expression in the 6-hydroxydopamine lesioned rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamines; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Denervation; Dopamine; Dopamine Agonists; Drug Synergism; Gene Expression Regulation; In Situ Hybridization; Male; Nerve Tissue Proteins; Neurons; Oxidopamine; Parkinson Disease, Secondary; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D1; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Receptor Agonists; Tachykinins | 1999 |
Prior D1 dopamine receptor stimulation is required to prime D2-mediated striatal Fos expression in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agonists; Gene Expression Regulation; Genes, fos; Male; Motor Activity; Oxidopamine; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Rotation | 1999 |
Substantia nigra pars reticulata units in 6-hydroxydopamine-lesioned rats: responses to striatal D2 dopamine receptor stimulation and subthalamic lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Corpus Striatum; Dopamine Antagonists; Kainic Acid; Male; Neurons; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Salicylamides; Substantia Nigra; Subthalamic Nucleus | 2000 |
Activation of extracellular signal-regulated protein kinases is associated with a sensitized locomotor response to D(2) dopamine receptor stimulation in unilateral 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agonists; Enzyme Inhibitors; Extracellular Space; Flavonoids; Locomotion; Male; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Oxidopamine; Phosphorylation; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Sympatholytics | 2000 |
Lack of synergism between caffeine and SKF 38393 on rotational behavior in 6-hydroxydopamine-denervated rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Caffeine; Dopamine Agonists; Drug Synergism; Male; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Rotation | 2000 |
Methylxanthines reverse the adipsic and aphagic syndrome induced by bilateral 6-hydroxydopamine lesions of the nigrostriatal pathway in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Caffeine; Corpus Striatum; Dextroamphetamine; Dopamine Agonists; Dopamine Antagonists; Drinking; Eating; Male; Neural Pathways; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sulpiride; Syndrome; Theophylline; Xanthines | 2000 |
Dynorphin modulates dopamine D1-receptor mediated turning behavior in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Behavior, Animal; Dopamine Agonists; Dynorphins; Immunohistochemistry; Injections, Intraventricular; Male; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine D1 | 2000 |
Action sites of rotation and unit firing induced by l-stepholidine and DA agonists in basal ganglia of 6-OHDA-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Berberine; Dopamine Agonists; Dopamine Antagonists; Electrophysiology; Male; Neostriatum; Oxidopamine; Rats; Rats, Sprague-Dawley; Rotation; Substantia Nigra | 1999 |
Effect of olanzapine on functional responses from sensitized D1-dopamine receptors in rats with neonatal dopamine loss.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Animals, Newborn; Antipsychotic Agents; Apomorphine; Benzodiazepines; Corpus Striatum; Dopamine; Dopamine Agonists; Female; Male; Motor Activity; Olanzapine; Oxidopamine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1 | 2001 |
Alterations in GAD67, dynorphin and enkephalin mRNA in striatal output neurons following priming in the 6-OHDA model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine Agonists; Down-Regulation; Drug Interactions; Drug Tolerance; Dynorphins; Enkephalins; Gene Expression; Glutamate Decarboxylase; Isoenzymes; Levodopa; Neostriatum; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; RNA, Messenger; Sympatholytics; Up-Regulation | 2001 |
Effect of microiontophoretic application of dopamine on subthalamic nucleus neuronal activity in normal rats and in rats with unilateral lesion of the nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Apomorphine; Dopamine; Dopamine Agonists; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Iontophoresis; Male; Neostriatum; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Dopamine D1; Substantia Nigra; Subthalamic Nucleus; Sympatholytics | 2001 |
The selective mGlu(5) receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D(2) receptors in the rat striatum: interactions with adenosine A(2a) receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Dopamine; Dopamine Agonists; Excitatory Amino Acid Agonists; Extracellular Space; Functional Laterality; Glycine; Injections, Intraventricular; Male; Microdialysis; Motor Activity; Neostriatum; Oxidopamine; Phenylacetates; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Stereotyped Behavior; Sympathectomy, Chemical | 2001 |
MK-801 alters the effects of priming with L-DOPA on dopamine D1 receptor-induced changes in neuropeptide mRNA levels in the rat striatal output neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Dopamine Agonists; Drug Interactions; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Excitatory Amino Acid Antagonists; Immunohistochemistry; Levodopa; Male; Motor Activity; Neostriatum; Neurons; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Protein Precursors; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tachykinins; Tyrosine 3-Monooxygenase | 2002 |
Phencyclidine supersensitivity in rats with neonatal dopamine loss.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Benzazepines; Benzodiazepines; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Haloperidol; Ketamine; Male; Motor Activity; Olanzapine; Oxidopamine; Phencyclidine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Sex Factors | 2002 |
EEG modifications in the cortex and striatum after dopaminergic priming in the 6-hydroxydopamine rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley | 2003 |
Dopamine effect on the stimulus pattern related changes in response characteristics of R/G horizontal cells in carp retina.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Animals; Carps; Dopamine; Dopamine Antagonists; Drug Interactions; In Vitro Techniques; Light; Membrane Potentials; Neurons; Oxidopamine; Receptors, Dopamine D2; Retina; Salicylamides; Time Factors | 2003 |
Dopaminergic mechanisms underlying bladder hyperactivity in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the nigrostriatal pathway.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzopyrans; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Injections, Intravenous; Injections, Intraventricular; Male; Microinjections; Oxazines; Oxidopamine; Parkinson Disease; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Substantia Nigra; Urinary Bladder; Urination | 2003 |
Ontogenetic quinpirole treatments fail to prime for D2 agonist-enhancement of locomotor activity in 6-hydroxydopamine-lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Biogenic Monoamines; Denervation; Dopamine Agonists; Female; Motor Activity; Neostriatum; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior; Sympatholytics | 2003 |
Limbic pallidal adaptations following long-term cessation of dopaminergic transmission: lack of upregulation of dopamine receptor function.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Benzazepines; Binding Sites; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Routes; Functional Laterality; Globus Pallidus; Immunohistochemistry; Iontophoresis; Male; Neurons; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sulpiride; Sympatholytics; Synaptic Transmission; Time; Tyrosine 3-Monooxygenase | 2004 |
Sustained extracellular signal-regulated kinase 1/2 phosphorylation in neonate 6-hydroxydopamine-lesioned rats after repeated D1-dopamine receptor agonist administration: implications for NMDA receptor involvement.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aminoacetonitrile; Animals; Animals, Newborn; Benzazepines; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Dopamine Agonists; Dopamine Antagonists; Enzyme Inhibitors; Female; Ketanserin; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Tissue Proteins; Nucleus Accumbens; Oxidopamine; Phosphorylation; Prefrontal Cortex; Protease Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT2 Receptor Antagonists | 2004 |
Behavioral responses to injections of muscimol into the subthalamic nucleus: temporal changes after nigrostriatal lesions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Corpus Striatum; Dopamine Agonists; Dose-Response Relationship, Drug; GABA Agonists; In Situ Hybridization; Male; Muscimol; Oxidopamine; Rats; Rats, Sprague-Dawley; Substantia Nigra; Subthalamic Nucleus; Time Factors; Tritium | 2005 |
The role of the phosphatidyinositol-linked D1 dopamine receptor in the pharmacology of SKF83959.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain Chemistry; Dopamine Agonists; Dopamine Antagonists; Hippocampus; Inositol 1,4,5-Trisphosphate; Male; Neostriatum; Oxidopamine; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics; Type C Phospholipases | 2005 |
Subchronic intermittent caffeine administration to unilaterally 6-hydroxydopamine-lesioned rats sensitizes turning behaviour in response to dopamine D(1) but not D(2) receptor agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Oxidopamine; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Sympathectomy, Chemical; Sympatholytics | 2005 |
The atypical dopamine D1 receptor agonist SKF 83959 induces striatal Fos expression in rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Benzazepines; Brain; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Models, Animal; Motor Activity; Oxidopamine; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Signal Transduction; Sympathectomy, Chemical | 2005 |
The signal transduction pathway for the dopamine D1 receptor in the guinea-pig cochlea.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Blotting, Western; Cochlea; Cochlear Nerve; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Female; Guinea Pigs; Immunohistochemistry; Isoquinolines; Male; Oxidopamine; Perfusion; Receptors, AMPA; Receptors, Dopamine D1; Signal Transduction; Sulfonamides; Sympathectomy, Chemical; Sympatholytics | 2006 |
Postnatal administration of D1 dopamine agonist reverses neonatal dopaminergic lesion-induced changes in striatal enkephalin and substance P systems.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Drug Interactions; Enkephalins; Female; Gene Expression; Humans; Male; Oxidopamine; Pregnancy; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Substance P | 2006 |
Histamine H3 receptor agonist- and antagonist-evoked vacuous chewing movements in 6-OHDA-lesioned rats occurs in an absence of change in microdialysate dopamine levels.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Catalepsy; Corpus Striatum; Dialysis Solutions; Dopamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Male; Mastication; Microdialysis; Motor Activity; Oxidopamine; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3; Stereotyped Behavior; Thiourea | 2006 |
Chronic SKF83959 induced less severe dyskinesia and attenuated L-DOPA-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Administration Schedule; Drug Interactions; Dyskinesia, Drug-Induced; Levodopa; Male; Movement; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spiperone; Sympatholytics; Time Factors | 2007 |
Activation of post-synaptic dopamine D₁ receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesics, Opioid; Animals; Benzazepines; Brain Chemistry; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Immunohistochemistry; Male; Methamphetamine; Mice; Mice, Inbred ICR; Morphine; Nucleus Accumbens; Oxidopamine; Protein Kinase Inhibitors; Raclopride; Receptors, Dopamine D1; Signal Transduction; Sympatholytics; Synapses; Tissue Plasminogen Activator; Tyrosine 3-Monooxygenase | 2007 |
Behavioral and biochemical correlates of the dyskinetic potential of dopaminergic agonists in the 6-OHDA lesioned rat.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Dopamine Agonists; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Indoles; Male; Motor Activity; Neural Pathways; Opioid Peptides; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; RNA, Messenger | 2008 |
Changes in apical dendritic structure correlate with sustained ERK1/2 phosphorylation in medial prefrontal cortex of a rat model of dopamine D1 receptor agonist sensitization.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aminoacetonitrile; Animals; Dendrites; Dopamine Agonists; Flavonoids; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidopamine; Phosphorylation; Prefrontal Cortex; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Sympatholytics | 2008 |
Priming of rotational behavior by a dopamine receptor agonist in Hemiparkinsonian rats: movement-dependent induction.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Functional Laterality; Male; Metyrapone; Movement; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Restraint, Physical; Rotarod Performance Test; Rotation; Time Factors | 2009 |
D2 receptor stimulation, but not D1, restores striatal equilibrium in a rat model of Parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2009 |
Differential involvement of D1 and D2 dopamine receptors in L-DOPA-induced angiogenic activity in a rat model of Parkinson's disease.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aminoacetonitrile; Animals; Antiparkinson Agents; Basal Ganglia; Benzazepines; Bromocriptine; Disease Models, Animal; Dopamine Agents; Dopamine D2 Receptor Antagonists; Extracellular Signal-Regulated MAP Kinases; Female; Levodopa; Neovascularization, Pathologic; Oxidopamine; Parkinsonian Disorders; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides | 2009 |
D1 priming enhances both D1- and D2-mediated rotational behavior and striatal Fos expression in 6-hydroxydopamine lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Corpus Striatum; Dopamine Agonists; Male; Oxidopamine; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2010 |
Dopamine agonists increase perseverative instrumental responses but do not restore habit formation in a rat model of Parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Conditioning, Operant; Corpus Striatum; Dopamine; Dopamine Agonists; Extinction, Psychological; Habits; Male; Oxidopamine; Parkinsonian Disorders; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Reward | 2010 |
Dyskinetic potential of dopamine agonists is associated with different striatonigral/striatopallidal zif-268 expression.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agonists; Dyskinesia, Drug-Induced; Early Growth Response Protein 1; Globus Pallidus; Indoles; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; RNA, Messenger; Substantia Nigra | 2010 |
Abnormal involuntary movement (AIM) expression following D2 dopamine agonist challenge is determined by the nature of prior dopamine receptor stimulation (priming) in 6-hydroxydopamine lesioned rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Dopamine Agonists; Male; Movement; Oxidopamine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 2013 |
Performance of movement in hemiparkinsonian rats influences the modifications induced by dopamine agonists in striatal efferent dynorphinergic neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Analysis of Variance; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dynorphins; Early Growth Response Protein 1; Enkephalins; Functional Laterality; Gene Expression Regulation; Male; Motor Neurons; Movement; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2013 |
L-DOPA treatment selectively restores spine density in dopamine receptor D2-expressing projection neurons in dyskinetic mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Cerebral Cortex; Corpus Striatum; Dendritic Spines; Dopamine Agonists; Dyskinesia, Drug-Induced; Levodopa; Male; Membrane Potentials; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Oxidopamine; Parkinsonian Disorders; Proto-Oncogene Proteins c-fos; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2014 |
Phosphodiesterase 10A controls D1-mediated facilitation of GABA release from striato-nigral projections under normal and dopamine-depleted conditions.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Colforsin; Corpus Striatum; Dopamine; Dopamine Agonists; Drug Interactions; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Mice; Neural Pathways; Oxidopamine; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphorylation; Potassium; Receptors, Dopamine D1; Substantia Nigra | 2014 |
Stronger Dopamine D1 Receptor-Mediated Neurotransmission in Dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Caudate Nucleus; Corpus Striatum; Dimerization; Dominance, Cerebral; Dopamine; Dopamine Agonists; Dyskinesia, Drug-Induced; Gene Expression Regulation; Levodopa; Macaca fascicularis; Male; Oxidopamine; Parkinsonian Disorders; Putamen; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D3 | 2015 |
α4 nicotinic acetylcholine receptor modulated by galantamine on nigrostriatal terminals regulates dopamine receptor-mediated rotational behavior.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Corpus Striatum; Dopamine Agonists; Galantamine; Locomotion; Male; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Nicotinic; Substantia Nigra | 2016 |
Inhibition of Glycogen Synthase Kinase-3β (GSK-3β) as potent therapeutic strategy to ameliorates L-dopa-induced dyskinesia in 6-OHDA parkinsonian rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cyclic AMP-Dependent Protein Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Dyskinesia, Drug-Induced; Glycogen Synthase Kinase 3 beta; Levodopa; Mitogen-Activated Protein Kinase 3; Oxidopamine; Parkinsonian Disorders; Phosphorylation; Rats; Receptors, Dopamine D1; tau Proteins; Thiadiazoles; Tyrosine 3-Monooxygenase | 2016 |
Anti-Parkinsonian and anti-dyskinetic profiles of two novel potent and selective nociceptin/orphanin FQ receptor agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetamides; Animals; Antiparkinson Agents; Corpus Striatum; Cricetinae; Dyskinesia, Drug-Induced; Extracellular Signal-Regulated MAP Kinases; Levodopa; Male; Nociceptin Receptor; Oxidopamine; Phosphorylation; Piperidines; Radioligand Assay; Rats; Receptors, Opioid | 2018 |
Bidirectional dopamine modulation of excitatory and inhibitory synaptic inputs to subthalamic neuron subsets containing α4β2 or α7 nAChRs.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzazepines; Dopamine; Dopamine D2 Receptor Antagonists; Excitatory Postsynaptic Potentials; Inhibitory Postsynaptic Potentials; Mice; Mice, Knockout; Oxidopamine; Piperazines; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Nicotinic; Reserpine; Subthalamic Nucleus; Synaptic Transmission | 2019 |
Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Benzimidazoles; Dyskinesia, Drug-Induced; Dystonia; Mice; Movement; Oxidopamine; Parkinsonian Disorders; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2021 |