sk&f-38393 has been researched along with dihydrexidine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 11 (57.89) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Brusniak, MY; DuRand, CJ; Huang, WH; Neve, KA; Pearlman, RS; Teeter, MM; Wiens, BL; Wilcox, DM; Wilcox, RE | 1 |
| Brewster, WK; Lee, RC; Lewis, MH; Lovenberg, TW; Mailman, RB; Mottola, DM; Nichols, DE; Riggs, RM | 1 |
| Arnsten, AF; Cai, JX; Goldman-Rakic, PS; Murphy, BL | 1 |
| Gilmore, JH; Lawler, CP; Mailman, RB; Nichols, DE; Southerland, SB; Watts, VJ | 1 |
| Friedman, E; Uryu, K; Wang, HY; Zhen, X | 1 |
| Gorelova, NA; Yang, CR | 1 |
| Gleason, SD; Witkin, JM | 1 |
| Kiehn, L; Mukai, ST; Saleuddin, AS | 1 |
| Lalley, PM | 1 |
| Lalley, PM; Mifflin, SW | 1 |
| da Silva, GVJ; da Silva, SR; Dos Anjos, LR; Dragačević, V; Fabišiková, A; Gajic, N; Gonzalez, ERP; Kalaba, P; Lubec, G; Neill, PJ; Palaretti, V; Pifl, C; Prado-Roller, A; Wieder, M; Zehl, M | 1 |
| Brewster, WK; Lewis, MH; Lovenberg, TW; Mailman, RB; Mottola, DM; Nichols, DE; Riggs, RM | 1 |
| Aviles-Garay, FA; Chakraborti, R; Mailman, RB; Nichols, DE; Snyder, SE; Watts, VJ | 1 |
| Asin, KE; Britton, DR; DiDomenico, S; Hong, Y; Lin, CW; Michaelides, MR; Shiosaki, K; Williams, M | 1 |
| Brewster, WK; Knoerzer, TA; Mailman, RB; Mottola, D; Nichols, DE; Watts, VJ | 1 |
| Ghosh, D; Mailman, RB; Nichols, DE; Snyder, SE; Watts, VJ | 1 |
| Brusniak, MY; Neve, KA; Pearlman, RS; Wilcox, RE | 1 |
| Asin, KE; Bayburt, EK; Britton, DR; DiDomenico, S; Hong, Y; Lin, CW; Michaelides, MR; Shiosaki, K | 1 |
| Brusniak, MY; DuRand, C; Ginsburg, B; Neve, KA; Pearlman, RS; Starr, S; Teeter, M; Tseng, T; Wilcox, RE | 1 |
19 other study(ies) available for sk&f-38393 and dihydrexidine
| Article | Year |
|---|---|
CoMFA-based prediction of agonist affinities at recombinant wild type versus serine to alanine point mutated D2 dopamine receptors.
Topics: Alanine; Amino Acid Substitution; Animals; Bromocriptine; Combinatorial Chemistry Techniques; Dopamine Agonists; Models, Molecular; Pergolide; Point Mutation; Radioligand Assay; Rats; Receptors, Dopamine D2; Recombinant Proteins; Serine; Structure-Activity Relationship; Tumor Cells, Cultured | 2000 |
Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Dopamine Agents; In Vitro Techniques; Male; Phenanthridines; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Spiperone | 1989 |
Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Aging; Animals; Behavior, Animal; Benzazepines; Cognition; Female; Macaca mulatta; Phenanthridines; Prefrontal Cortex; Psychomotor Performance; Receptors, Dopamine D1; Reserpine | 1994 |
Dopamine D1 receptors: efficacy of full (dihydrexidine) vs. partial (SKF38393) agonists in primates vs. rodents.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclases; Animals; Dopamine Agents; Macaca mulatta; Male; Parkinson Disease; Phenanthridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Species Specificity | 1993 |
D1 dopamine receptor agonists mediate activation of p38 mitogen-activated protein kinase and c-Jun amino-terminal kinase by a protein kinase A-dependent mechanism in SK-N-MC human neuroblastoma cells.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinases; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Phosphorylation; Receptors, Dopamine D1; Tumor Cells, Cultured | 1998 |
Dopamine D1/D5 receptor activation modulates a persistent sodium current in rat prefrontal cortical neurons in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alkaloids; Animals; Benzazepines; Benzophenanthridines; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Phenanthridines; Prefrontal Cortex; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D5; Sodium; Tetrodotoxin | 2000 |
Effects of dopamine D1 receptor full agonists in rats trained to discriminate SKF 38393.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Appetitive Behavior; Conditioning, Operant; Discrimination Learning; Dopamine Agonists; Drug Interactions; Isoquinolines; Male; Motivation; Naphthols; Phenanthridines; Prodrugs; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes | 2004 |
Dopamine stimulates snail albumen gland glycoprotein secretion through the activation of a D1-like receptor.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Exocrine Glands; Fresh Water; Glycoproteins; Phenanthridines; Receptors, Dopamine D1; Reproduction; Signal Transduction; Snails; Tetrahydronaphthalenes | 2004 |
D1/D2-dopamine receptor agonist dihydrexidine stimulates inspiratory motor output and depresses medullary expiratory neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Benzazepines; Cats; Dopamine Agonists; Exhalation; Inhalation; Male; Motor Neurons; Neural Inhibition; Phenanthridines; Phrenic Nerve; Pressure; Receptors, Dopamine D1; Receptors, Dopamine D2; Respiratory Center; Respiratory Muscles; Synaptic Transmission; Time Factors | 2009 |
Opposing effects on the phrenic motor pathway attributed to dopamine-D1 and -D3/D2 receptor activation.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Cats; Dopamine Agonists; Efferent Pathways; Male; Phenanthridines; Phrenic Nerve; Piribedil; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Respiratory System | 2012 |
Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Catecholamines; Phenanthridines; Receptors, Dopamine D1 | 2022 |
trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist.
Topics: Adenylyl Cyclases; Animals; Computer Simulation; Dopamine Agents; In Vitro Techniques; Molecular Conformation; Phenanthridines; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship | 1990 |
Synthesis and evaluation of 6,7-dihydroxy-2,3,4,8,9,13b-hexahydro-1H- benzo[6,7]cyclohepta[1,2,3-ef][3]benzazepine, 6,7-dihydroxy- 1,2,3,4,8,12b-hexahydroanthr[10,4a,4-cd]azepine, and 10-(aminomethyl)-9,10- dihydro-1,2-dihydroxyanthracene as conformationa
Topics: Animals; Anthracenes; Azepines; Benzazepines; Dopamine; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine | 1995 |
(5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-azacyclopent-1- ena[c]-phenanthrene-9,10-diol (A-86929): a potent and selective dopamine D1 agonist that maintains behavioral efficacy following repeated administration and characterization of its diac
Topics: Acetylation; Animals; Behavior, Animal; Drug Administration Schedule; Humans; Prodrugs; Protein Precursors; Pyridines; Quinolones; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Structure-Activity Relationship; Tetrahydronaphthalenes; Thiophenes | 1995 |
Dopaminergic benzo[a]phenanthridines: resolution and pharmacological evaluation of the enantiomers of dihydrexidine, the full efficacy D1 dopamine receptor agonist.
Topics: Animals; Benzazepines; Binding Sites; Corpus Striatum; Dopamine Agents; Humans; Male; Mice; Phenanthridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereoisomerism; Transfection | 1994 |
9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: a potent full dopamine D1 agonist containing a rigid-beta-phenyldopamine pharmacophore.
Topics: Adenylyl Cyclases; Animals; Benzazepines; Corpus Striatum; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Isoquinolines; Macaca mulatta; Male; Naphthols; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Tumor Cells, Cultured | 1996 |
Comparative molecular field analysis-based prediction of drug affinities at recombinant D1A dopamine receptors.
Topics: Animals; Cell Line; Chlorocebus aethiops; Computer Graphics; Dopamine; Dopamine Agonists; Glioma; Humans; Kinetics; Models, Molecular; Receptors, Dopamine D1; Recombinant Proteins; Structure-Activity Relationship; Tumor Cells, Cultured | 1996 |
Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo.
Topics: Adenylyl Cyclases; Animals; Benzazepines; Binding, Competitive; Cell Membrane; Corpus Striatum; Dopamine Agonists; Dopamine Antagonists; Fishes; Mice; Molecular Structure; Oxidopamine; Parkinson Disease, Secondary; Quinolones; Receptors, Dopamine; Retina; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Tritium; Yohimbine | 1997 |
CoMFA-based prediction of agonist affinities at recombinant D1 vs D2 dopamine receptors.
Topics: Animals; Binding Sites; Databases, Factual; Dopamine Agonists; Humans; Ligands; Macaca mulatta; Models, Molecular; Molecular Conformation; Protein Structure, Secondary; Rats; Receptors, Dopamine D1; Receptors, Dopamine D2; Recombinant Proteins; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |