Page last updated: 2024-09-05

sk&f 107260 and aspirin

sk&f 107260 has been researched along with aspirin in 1 studies

*Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) [MeSH]

*Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5) [MeSH]

Compound Research Comparison

Studies
(sk&f 107260)
Trials
(sk&f 107260)
Recent Studies (post-2010)
(sk&f 107260)
Studies
(aspirin)
Trials
(aspirin)
Recent Studies (post-2010) (aspirin)
110048,9476,81713,778

Protein Interaction Comparison

ProteinTaxonomysk&f 107260 (IC50)aspirin (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.35
Integrin beta-3Homo sapiens (human)5
Prostaglandin G/H synthase 1Ovis aries (sheep)0.8252
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)1.375
Integrin alpha-IIbHomo sapiens (human)5
Prostaglandin G/H synthase 1Homo sapiens (human)2.271
Substance-P receptorCavia porcellus (domestic guinea pig)2.4
Prostaglandin G/H synthase 2Homo sapiens (human)2.15
Urotensin-2 receptorRattus norvegicus (Norway rat)0.3
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)2.4
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.35
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4081

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boike, S; Freed, MI; Jorkasky, DK; Zariffa, N1

Other Studies

1 other study(ies) available for sk&f 107260 and aspirin

ArticleYear
Effect of acetylsalicylic acid on inhibition of ex vivo platelet aggregation and secretion by SKF 107260, a novel GPIIb/IIIa receptor antagonist.
    Thrombosis and haemostasis, 1994, Volume: 72, Issue:4

    Topics: Adenosine Triphosphate; Adult; Aspirin; Blood Platelets; Collagen; Drug Synergism; Female; Humans; Male; Peptides, Cyclic; Platelet Aggregation; Platelet Membrane Glycoproteins; Sex Characteristics

1994