Page last updated: 2024-09-03

sk&f 105685 and sirolimus

sk&f 105685 has been researched along with sirolimus in 3 studies

Compound Research Comparison

Studies
(sk&f 105685)
Trials
(sk&f 105685)
Recent Studies (post-2010)
(sk&f 105685)
Studies
(sirolimus)
Trials
(sirolimus)
Recent Studies (post-2010) (sirolimus)
220020,7112,36811,516

Protein Interaction Comparison

ProteinTaxonomysk&f 105685 (IC50)sirolimus (IC50)
Bile salt export pumpHomo sapiens (human)10
ATP-dependent translocase ABCB1Homo sapiens (human)1.25
Cytochrome P450 3A4Homo sapiens (human)2
Cytochrome P450 2C9 Homo sapiens (human)2
Peptidyl-prolyl cis-trans isomerase FKBP1AMus musculus (house mouse)0.001
Cytochrome P450 2C19Homo sapiens (human)4
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1AHomo sapiens (human)0.0042
Regulatory-associated protein of mTORHomo sapiens (human)0.225
Target of rapamycin complex subunit LST8Homo sapiens (human)0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.9
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)1.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
First, MR1
Badger, AM; Bugelski, PJ; Kaplan, JM; Newman-Tarr, T; Olivera, DL; Ruggieri, EV1
Surdacka, E; Surdacki, A; Sułowicz, W1

Reviews

1 review(s) available for sk&f 105685 and sirolimus

ArticleYear
[New immunosuppressive drugs in transplantation].
    Przeglad lekarski, 1994, Volume: 51, Issue:8

    Topics: Biphenyl Compounds; Cyclosporine; Guanidines; Humans; Immunosuppressive Agents; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; Spiro Compounds; Tacrolimus; Transplantation Immunology

1994

Other Studies

2 other study(ies) available for sk&f 105685 and sirolimus

ArticleYear
Renal transplantation for the nephrologist: new immunosuppressive drugs.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 19, Issue:1

    Topics: Animals; Guanidines; Humans; Immunosuppressive Agents; Kidney Transplantation; Mycophenolic Acid; Polyenes; Ribonucleosides; Sirolimus; Spiro Compounds; Tacrolimus

1992
Inhibition of lymphoproliferative responses by SK&F 105685, a novel anti-arthritic agent.
    Journal of clinical & laboratory immunology, 1991, Volume: 36, Issue:4

    Topics: Animals; Arginine; Arthritis; Concanavalin A; Cyclosporine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; omega-N-Methylarginine; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Spiro Compounds; Spleen; Time Factors; Tumor Cells, Cultured

1991