sk&f 104976 has been researched along with lovastatin in 2 studies
Studies (sk&f 104976) | Trials (sk&f 104976) | Recent Studies (post-2010) (sk&f 104976) | Studies (lovastatin) | Trials (lovastatin) | Recent Studies (post-2010) (lovastatin) |
---|---|---|---|---|---|
10 | 0 | 1 | 4,828 | 698 | 873 |
Protein | Taxonomy | sk&f 104976 (IC50) | lovastatin (IC50) |
---|---|---|---|
Chain A, Antigen Cd11a (p180) | Homo sapiens (human) | 2.4 | |
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0261 | |
Integrin beta-2 | Homo sapiens (human) | 3.09 | |
Intercellular adhesion molecule 1 | Homo sapiens (human) | 3.78 | |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 8.753 | |
ATP-dependent translocase ABCB1 | Homo sapiens (human) | 10 | |
Neutrophil elastase | Homo sapiens (human) | 0.027 | |
Insulin receptor | Rattus norvegicus (Norway rat) | 0.02 | |
Integrin alpha-L | Homo sapiens (human) | 3.09 | |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 8.753 | |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.02 | |
3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0529 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Adams, JL; Berkhout, TA; Bossard, MJ; Mayer, RJ | 1 |
Bentzen, C; Berkhout, TA; Jackson, B; Niesor, E; Patel, DD; Simon, HM; Suckling, KE | 1 |
2 other study(ies) available for sk&f 104976 and lovastatin
Article | Year |
---|---|
Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells.
Topics: Carcinoma, Hepatocellular; Cell-Free System; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Liver Neoplasms; Lovastatin; Mevalonic Acid; Oxidoreductases; Receptors, LDL; Sterol 14-Demethylase; Sterols; Tumor Cells, Cultured | 1991 |
The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Acetates; Anticholesteremic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Diphosphonates; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lanosterol; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Receptors, LDL; RNA, Messenger; Transcription, Genetic; Tritium; Tumor Cells, Cultured | 1996 |