Page last updated: 2024-09-03

sk&f 104976 and lovastatin

sk&f 104976 has been researched along with lovastatin in 2 studies

Compound Research Comparison

Studies
(sk&f 104976)
Trials
(sk&f 104976)
Recent Studies (post-2010)
(sk&f 104976)
Studies
(lovastatin)
Trials
(lovastatin)
Recent Studies (post-2010) (lovastatin)
10014,828698873

Protein Interaction Comparison

ProteinTaxonomysk&f 104976 (IC50)lovastatin (IC50)
Chain A, Antigen Cd11a (p180)Homo sapiens (human)2.4
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.0261
Integrin beta-2Homo sapiens (human)3.09
Intercellular adhesion molecule 1Homo sapiens (human)3.78
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)8.753
ATP-dependent translocase ABCB1Homo sapiens (human)10
Neutrophil elastaseHomo sapiens (human)0.027
Insulin receptor Rattus norvegicus (Norway rat)0.02
Integrin alpha-LHomo sapiens (human)3.09
Sodium-dependent noradrenaline transporter Homo sapiens (human)8.753
Prostaglandin G/H synthase 2Homo sapiens (human)0.02
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0529

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, JL; Berkhout, TA; Bossard, MJ; Mayer, RJ1
Bentzen, C; Berkhout, TA; Jackson, B; Niesor, E; Patel, DD; Simon, HM; Suckling, KE1

Other Studies

2 other study(ies) available for sk&f 104976 and lovastatin

ArticleYear
Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells.
    The Journal of biological chemistry, 1991, Oct-25, Volume: 266, Issue:30

    Topics: Carcinoma, Hepatocellular; Cell-Free System; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Liver Neoplasms; Lovastatin; Mevalonic Acid; Oxidoreductases; Receptors, LDL; Sterol 14-Demethylase; Sterols; Tumor Cells, Cultured

1991
The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    The Journal of biological chemistry, 1996, Jun-14, Volume: 271, Issue:24

    Topics: Acetates; Anticholesteremic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Diphosphonates; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lanosterol; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Receptors, LDL; RNA, Messenger; Transcription, Genetic; Tritium; Tumor Cells, Cultured

1996