sk&f 104976 has been researched along with lanosterol in 10 studies
Studies (sk&f 104976) | Trials (sk&f 104976) | Recent Studies (post-2010) (sk&f 104976) | Studies (lanosterol) | Trials (lanosterol) | Recent Studies (post-2010) (lanosterol) |
---|---|---|---|---|---|
10 | 0 | 1 | 1,010 | 8 | 335 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (40.00) | 18.2507 |
2000's | 5 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (10.00) | 2.80 |
Authors | Studies |
---|---|
Adams, JL; Berkhout, TA; Bossard, MJ; Mayer, RJ | 1 |
Bentzen, C; Berkhout, TA; Jackson, B; Niesor, E; Patel, DD; Simon, HM; Suckling, KE | 1 |
Ferruelo, AJ; Gómez-Coronado, D; Lasunción, MA; Martínez-Botas, J; Suárez, Y | 2 |
Fernández, C; Ferruelo, AJ; Gómez-Coronado, D; Lasunción, MA; Ledo, B; Martín, M; Suárez, Y; Vega, MA | 1 |
Fernández, C; Gómez-Coronado, D; Lasunción, MA; Lobo Md, Mdel V | 1 |
Gómez-Mampaso, E; Lasunción, MA; Matilla, J; Montero, MT | 1 |
Dávalos, A; de la Peña, G; Fernández-Hernando, C; Lasunción, MA; Martín-Sánchez, C; Sánchez-Martín, CC | 1 |
Busto, R; Cano, S; Dávalos, A; de la Peña, G; Giera, M; Herrera, E; Lasunción, MA; Sánchez-Wandelmer, J | 1 |
Leaver, DJ; Madan, B; Nes, WD; Virshup, DM | 1 |
1 review(s) available for sk&f 104976 and lanosterol
Article | Year |
---|---|
Unearthing the Janus-face cholesterogenesis pathways in cancer.
Topics: Animals; Anticholesteremic Agents; Antineoplastic Agents; Benzylamines; Cholesterol; Humans; Lanosterol; Neoplasms; Terbinafine; Thiophenes | 2022 |
9 other study(ies) available for sk&f 104976 and lanosterol
Article | Year |
---|---|
Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells.
Topics: Carcinoma, Hepatocellular; Cell-Free System; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxymethylglutaryl CoA Reductases; Lanosterol; Liver Neoplasms; Lovastatin; Mevalonic Acid; Oxidoreductases; Receptors, LDL; Sterol 14-Demethylase; Sterols; Tumor Cells, Cultured | 1991 |
The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Acetates; Anticholesteremic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Diphosphonates; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Kinetics; Lanosterol; Lipoproteins, LDL; Liver Neoplasms; Lovastatin; Receptors, LDL; RNA, Messenger; Transcription, Genetic; Tritium; Tumor Cells, Cultured | 1996 |
Induction of apoptosis in p53-null HL-60 cells by inhibition of lanosterol 14-alpha demethylase.
Topics: Apoptosis; Cell Division; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Flow Cytometry; Genes, p53; HL-60 Cells; Humans; Lanosterol; Microscopy, Fluorescence; Oxidoreductases; Sterol 14-Demethylase; Time Factors | 1998 |
Cholesterol starvation decreases p34(cdc2) kinase activity and arrests the cell cycle at G2.
Topics: CDC2 Protein Kinase; Cell Cycle; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; G2 Phase; Histones; HL-60 Cells; Humans; Lanosterol; Oxidoreductases; Phosphorylation; Sterol 14-Demethylase | 1999 |
Differential effects of ergosterol and cholesterol on Cdk1 activation and SRE-driven transcription.
Topics: Base Sequence; CDC2 Protein Kinase; Cell Cycle; Cell Division; Cell Line; Cholesterol; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Ergosterol; Humans; Kinetics; Lanosterol; Transcription, Genetic | 2002 |
Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation.
Topics: Apoptosis; CDC2 Protein Kinase; Cell Nucleus; Cholesterol; Chromosome Aberrations; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; G1 Phase; G2 Phase; Giant Cells; HL-60 Cells; Humans; Lanosterol; Microscopy, Electron, Transmission; Mitosis; Oxidoreductases; Polyploidy; S Phase; Sterol 14-Demethylase | 2004 |
Geranylgeraniol regulates negatively caspase-1 autoprocessing: implication in the Th1 response against Mycobacterium tuberculosis.
Topics: Caspase 1; Diterpenes; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Interferon-gamma; Interleukin-1; Interleukin-18; Lanosterol; Male; Mycobacterium tuberculosis; Th1 Cells | 2004 |
Cholesterol starvation induces differentiation of human leukemia HL-60 cells.
Topics: Cell Differentiation; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; HL-60 Cells; Humans; Lanosterol; MAP Kinase Signaling System; Oxidoreductases; Sterol 14-Demethylase | 2007 |
Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes.
Topics: 3T3-L1 Cells; Animals; Caveolae; Caveolin 1; Cell Membrane; Cholesterol; Dehydrocholesterols; Enzyme Inhibitors; G(M1) Ganglioside; Lanosterol; Membrane Microdomains; Mice; Receptor, Insulin; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol | 2009 |