sk&f 104856 has been researched along with yohimbine in 8 studies
| Studies (sk&f 104856) | Trials (sk&f 104856) | Recent Studies (post-2010) (sk&f 104856) | Studies (yohimbine) | Trials (yohimbine) | Recent Studies (post-2010) (yohimbine) |
|---|---|---|---|---|---|
| 14 | 0 | 0 | 5,893 | 253 | 532 |
| Protein | Taxonomy | sk&f 104856 (IC50) | yohimbine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.02 | |
| D(2) dopamine receptor | Homo sapiens (human) | 2.06 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0428 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0466 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.126 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.013 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.126 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.074 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.689 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bondinell, W; Hieble, JP; Ruffolo, RR | 1 |
| Brooks, DP; DePalma, PD; Fredrickson, TA; Hieble, JP; Nichols, AJ; Ruffolo, RR | 1 |
| Gleason, MM; Hieble, JP | 1 |
| Chou, B; Green, PG; Khasar, SG; Levine, JD | 1 |
| Corcoran, ME; Pelletier, MR | 1 |
| Oriowo, MA | 1 |
| Camacho, F; Smith, CP; Vargas, HM; Winslow, JT | 1 |
| Szreder, Z | 1 |
1 review(s) available for sk&f 104856 and yohimbine
| Article | Year |
|---|---|
Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Humans; Molecular Conformation; Molecular Structure; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1995 |
7 other study(ies) available for sk&f 104856 and yohimbine
| Article | Year |
|---|---|
Cardiovascular actions of a new selective postjunctional alpha-adrenoceptor antagonist, SK&F 104856, in normotensive and hypertensive dogs.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dogs; Female; Heart Rate; Hypertension, Renovascular; Male; Myocardial Contraction; Prazosin; Yohimbine | 1992 |
Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Dibenzazepines; Imidazoles; Indoles; Isoindoles; Lung; Mice; Neuroblastoma; Neurons; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Tumor Cells, Cultured; Yohimbine | 1991 |
Peripheral nociceptive effects of alpha 2-adrenergic receptor agonists in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Calcimycin; Clonidine; Dose-Response Relationship, Drug; Imidazoles; Indoles; Isoindoles; Male; Norepinephrine; Pain Measurement; Peripheral Nervous System; Quinoxalines; Rats; Rats, Sprague-Dawley; Yohimbine | 1995 |
Infusions of alpha-2 noradrenergic agonists and antagonists into the amygdala: effects on kindling.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Benzazepines; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Functional Laterality; Idazoxan; Infusions, Parenteral; Kindling, Neurologic; Male; Rats; Receptors, Adrenergic, alpha-2; Seizures; Xylazine; Yohimbine | 1993 |
The prejunctional inhibitory effect of alpha-methylnoradrenaline in the rat vas deferens is not mediated via alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; Imidazoles; Isometric Contraction; Male; Neuromuscular Junction; Nordefrin; Phenoxybenzamine; Phentolamine; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vas Deferens; Vasoconstrictor Agents; Yohimbine | 1995 |
Alpha 2-adrenoceptor antagonists potentiate acetylcholinesterase inhibitor effects on passive avoidance learning in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Benzazepines; Cholinesterase Inhibitors; Drug Synergism; Galantamine; Idazoxan; Male; Physostigmine; Rats; Rats, Sprague-Dawley; Tacrine; Yohimbine | 1996 |
Do cardiovascular mechanisms participate in thermoregulatory activity of alpha 2-adrenoceptor agonists and antagonists in rabbits?
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzazepines; Body Temperature; Body Temperature Regulation; Brimonidine Tartrate; Cold Temperature; Ear; Energy Metabolism; Fever; Hemodynamics; Lipopolysaccharides; Male; Pyrogens; Quinoxalines; Rabbits; Yohimbine | 1997 |