Page last updated: 2024-09-03

sk&f 104856 and prazosin

sk&f 104856 has been researched along with prazosin in 3 studies

Compound Research Comparison

Studies (sk&f 104856)	Trials (sk&f 104856)	Recent Studies (post-2010) (sk&f 104856)	Studies (prazosin)	Trials (prazosin)	Recent Studies (post-2010) (prazosin)
14	0	0	7,914	713	682

Protein Interaction Comparison

Protein	Taxonomy	prazosin (IC50)
Solute carrier family 22 member 1	Homo sapiens (human)	5.87
Interstitial collagenase	Homo sapiens (human)	4.036
Alpha-2A adrenergic receptor	Homo sapiens (human)	2.638
Matrix metalloproteinase-9	Homo sapiens (human)	6.963
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	0.0078
Alpha-2B adrenergic receptor	Homo sapiens (human)	0.29
Alpha-2C adrenergic receptor	Homo sapiens (human)	0.647
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
Alpha-1D adrenergic receptor	Homo sapiens (human)	0.0007
Bromodomain-containing protein 2	Homo sapiens (human)	0.0009
Alpha-1A adrenergic receptor	Homo sapiens (human)	0.0006
Alpha-1B adrenergic receptor	Homo sapiens (human)	0.0006
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	4.118
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	0.0008
5-hydroxytryptamine receptor 7	Cavia porcellus (domestic guinea pig)	9.9
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	1.5849
Multidrug and toxin extrusion protein 1	Homo sapiens (human)	1.6

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (66.67)	18.2507
2000's	1 (33.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ballard, S; Blagg, J; Fox, D; Kenny, B	1
Pedretti, A; Testa, B; Villa, L; Vistoli, G	1
Brooks, DP; DePalma, PD; Fredrickson, TA; Hieble, JP; Nichols, AJ; Ruffolo, RR	1

Reviews

1 review(s) available for sk&f 104856 and prazosin

Article	Year
Pharmacological options in the treatment of benign prostatic hyperplasia. Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9 Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Controlled Clinical Trials as Topic; Endothelins; Enzyme Inhibitors; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Structure-Activity Relationship	1997

Article

Year

Pharmacological options in the treatment of benign prostatic hyperplasia.

Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Controlled Clinical Trials as Topic; Endothelins; Enzyme Inhibitors; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Adrenergic, alpha; Structure-Activity Relationship

1997

Other Studies

2 other study(ies) available for sk&f 104856 and prazosin

Article	Year
Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Chemical Phenomena; Chemistry, Physical; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Receptors, Adrenergic, alpha-1; Solvents	2005
Cardiovascular actions of a new selective postjunctional alpha-adrenoceptor antagonist, SK&F 104856, in normotensive and hypertensive dogs. British journal of pharmacology, 1992, Volume: 105, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dogs; Female; Heart Rate; Hypertension, Renovascular; Male; Myocardial Contraction; Prazosin; Yohimbine	1992

Article

Year

Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses.

Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15

Topics: Chemical Phenomena; Chemistry, Physical; Ligands; Models, Molecular; Molecular Conformation; Monte Carlo Method; Quantitative Structure-Activity Relationship; Receptors, Adrenergic, alpha-1; Solvents

2005

Cardiovascular actions of a new selective postjunctional alpha-adrenoceptor antagonist, SK&F 104856, in normotensive and hypertensive dogs.

British journal of pharmacology, 1992, Volume: 105, Issue:4

Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Dogs; Female; Heart Rate; Hypertension, Renovascular; Male; Myocardial Contraction; Prazosin; Yohimbine

1992