Page last updated: 2024-09-03

sk&f 104078 and oxymetazoline

sk&f 104078 has been researched along with oxymetazoline in 4 studies

Compound Research Comparison

Studies
(sk&f 104078)
Trials
(sk&f 104078)
Recent Studies (post-2010)
(sk&f 104078)
Studies
(oxymetazoline)
Trials
(oxymetazoline)
Recent Studies (post-2010) (oxymetazoline)
2900738128159

Protein Interaction Comparison

ProteinTaxonomysk&f 104078 (IC50)oxymetazoline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.578
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.261
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.332
Alpha-2A adrenergic receptorHomo sapiens (human)0.023
Cytochrome P450 2D6Homo sapiens (human)0.2
Alpha-2B adrenergic receptorHomo sapiens (human)1.273
Alpha-2C adrenergic receptorHomo sapiens (human)2.633
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0056
Alpha-1D adrenergic receptorHomo sapiens (human)2.844
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.285
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.578
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0056
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.056
5-hydroxytryptamine receptor 6Homo sapiens (human)1.67

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bondinell, WE; Hieble, JP; Ruffolo, RR1
Gleason, MM; Hieble, JP1
Göthert, M; Molderings, GJ1
Duda, T; Galoian, K; Sharma, RK; Venkataraman, V1

Reviews

1 review(s) available for sk&f 104078 and oxymetazoline

ArticleYear
Alpha- and beta-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification.
    Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18

    Topics: Animals; Humans; Molecular Biology; Molecular Structure; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1995

Other Studies

3 other study(ies) available for sk&f 104078 and oxymetazoline

ArticleYear
Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Dibenzazepines; Imidazoles; Indoles; Isoindoles; Lung; Mice; Neuroblastoma; Neurons; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Tumor Cells, Cultured; Yohimbine

1991
Subtype determination of presynaptic alpha 2-autoreceptors in the rabbit pulmonary artery and human saphenous vein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzazepines; Cattle; Dioxanes; Electric Stimulation; Humans; Idazoxan; Imidazoles; In Vitro Techniques; Oxymetazoline; Phentolamine; Presynaptic Terminals; Pulmonary Artery; Rabbits; Rats; Receptors, Adrenergic, alpha-2; Saphenous Vein; Tritium

1995
Molecular and pharmacological identity of the alpha 2D-adrenergic receptor subtype in bovine retina and its photoreceptors.
    Molecular and cellular biochemistry, 1996, Jun-21, Volume: 159, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Benzazepines; Cattle; Gene Expression; Humans; Ligands; Mice; Molecular Sequence Data; Oxymetazoline; Photoreceptor Cells; Prazosin; Rats; Receptors, Adrenergic, alpha-2; Retina; Sequence Alignment; Yohimbine

1996