Page last updated: 2024-09-03

sk&f 104078 and idazoxan

sk&f 104078 has been researched along with idazoxan in 4 studies

Compound Research Comparison

Studies
(sk&f 104078)
Trials
(sk&f 104078)
Recent Studies (post-2010)
(sk&f 104078)
Studies
(idazoxan)
Trials
(idazoxan)
Recent Studies (post-2010) (idazoxan)
29001,49940123

Protein Interaction Comparison

ProteinTaxonomysk&f 104078 (IC50)idazoxan (IC50)
Alpha-2A adrenergic receptorHomo sapiens (human)0.0083
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-2B adrenergic receptorHomo sapiens (human)0.0195
Alpha-2C adrenergic receptorHomo sapiens (human)0.0537
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0195
Alpha-1A adrenergic receptorHomo sapiens (human)2.884
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0195

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bondinell, W; Hieble, JP; Ruffolo, RR1
Arnsten, AF; Contant, TA1
Clarke, RW; Harris, J1
Göthert, M; Molderings, GJ1

Reviews

1 review(s) available for sk&f 104078 and idazoxan

ArticleYear
Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.
    Journal of medicinal chemistry, 1995, Sep-15, Volume: 38, Issue:19

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Humans; Molecular Conformation; Molecular Structure; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship

1995

Other Studies

3 other study(ies) available for sk&f 104078 and idazoxan

ArticleYear
Alpha-2 adrenergic agonists decrease distractibility in aged monkeys performing the delayed response task.
    Psychopharmacology, 1992, Volume: 108, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Attention; Benzazepines; Clonidine; Cognition; Conditioning, Operant; Dioxanes; Female; Idazoxan; Macaca mulatta; Memory; Psychomotor Performance

1992
An analysis of adrenergic influences on the sural-gastrocnemius reflex of the decerebrated rabbit.
    Experimental brain research, 1992, Volume: 92, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Decerebrate State; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulation; Female; Idazoxan; Injections, Spinal; Male; Muscles; Prazosin; Rabbits; Reflex; Sural Nerve; Sympathetic Nervous System; Yohimbine

1992
Subtype determination of presynaptic alpha 2-autoreceptors in the rabbit pulmonary artery and human saphenous vein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzazepines; Cattle; Dioxanes; Electric Stimulation; Humans; Idazoxan; Imidazoles; In Vitro Techniques; Oxymetazoline; Phentolamine; Presynaptic Terminals; Pulmonary Artery; Rabbits; Rats; Receptors, Adrenergic, alpha-2; Saphenous Vein; Tritium

1995