sk&f 104078 has been researched along with clonidine in 3 studies
| Studies (sk&f 104078) | Trials (sk&f 104078) | Recent Studies (post-2010) (sk&f 104078) | Studies (clonidine) | Trials (clonidine) | Recent Studies (post-2010) (clonidine) |
|---|---|---|---|---|---|
| 29 | 0 | 0 | 13,692 | 2,044 | 1,394 |
| Protein | Taxonomy | sk&f 104078 (IC50) | clonidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.101 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0115 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.002 | |
| Nischarin | Rattus norvegicus (Norway rat) | 0.3662 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bondinell, W; Hieble, JP; Ruffolo, RR | 1 |
| Arnsten, AF; Contant, TA | 1 |
| Gleason, MM; Hieble, JP | 1 |
1 review(s) available for sk&f 104078 and clonidine
| Article | Year |
|---|---|
Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Humans; Molecular Conformation; Molecular Structure; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1995 |
2 other study(ies) available for sk&f 104078 and clonidine
| Article | Year |
|---|---|
Alpha-2 adrenergic agonists decrease distractibility in aged monkeys performing the delayed response task.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Attention; Benzazepines; Clonidine; Cognition; Conditioning, Operant; Dioxanes; Female; Idazoxan; Macaca mulatta; Memory; Psychomotor Performance | 1992 |
Ability of SK&F 104078 and SK&F 104856 to identify alpha-2 adrenoceptor subtypes in NCB20 cells and guinea pig lung.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Brimonidine Tartrate; Cells, Cultured; Clonidine; Cricetinae; Dibenzazepines; Imidazoles; Indoles; Isoindoles; Lung; Mice; Neuroblastoma; Neurons; Oxymetazoline; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Tumor Cells, Cultured; Yohimbine | 1991 |