Compounds > sk&f 102922
Page last updated: 2024-09-03

sk&f 102922 and indomethacin

sk&f 102922 has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(sk&f 102922)		Trials
(sk&f 102922)		Recent Studies (post-2010)
(sk&f 102922)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
140029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomysk&f 102922 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Banner, BL; Chiu, AM; Cohen, N; Focella, A; Lopresti, RJ; O'Donnell, M; Schaer, B; Todaro, L; Weber, G; Zenchoff, GB1
Burakoff, R; Burton, MB; Lee, SY; Percy, WH; Tolentino, T1
Crooke, ST; Hoffman, K; Mong, S; Wu, HL1

Other Studies

3 other study(ies) available for sk&f 102922 and indomethacin

ArticleYear
3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Animals; Benzopyrans; Chemical Phenomena; Chemistry; Chromans; Guinea Pigs; Leukotriene Antagonists; Male; Models, Molecular; Rats; Receptors, Immunologic; Receptors, Leukotriene; Stereoisomerism; Structure-Activity Relationship

1989
Leukotriene D4 excitation of rabbit distal colon arises in the region of the muscularis mucosae.
    The American journal of physiology, 1990, Volume: 259, Issue:5 Pt 1

    Topics: Animals; Colon; Dicarboxylic Acids; Electric Stimulation; Electrophysiology; Evoked Potentials; Gastrointestinal Motility; In Vitro Techniques; Indomethacin; Kinetics; Male; Muscle, Smooth; Rabbits; SRS-A

1990
Leukotriene-induced hydrolysis of inositol lipids in guinea pig lung: mechanism of signal transduction for leukotriene-D4 receptors.
    Molecular pharmacology, 1987, Volume: 31, Issue:1

    Topics: Animals; Dicarboxylic Acids; Guinea Pigs; Indomethacin; Inositol Phosphates; Leukotriene E4; Lung; Muscle, Smooth; Phosphatidylinositols; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thromboxane B2

1987