sk&f 102922 has been researched along with fpl 55712 in 8 studies
| Studies (sk&f 102922) | Trials (sk&f 102922) | Recent Studies (post-2010) (sk&f 102922) | Studies (fpl 55712) | Trials (fpl 55712) | Recent Studies (post-2010) (fpl 55712) |
|---|---|---|---|---|---|
| 14 | 0 | 0 | 393 | 2 | 3 |
| 14 | 0 | 0 | 8 | 0 | 0 |
| Protein | Taxonomy | sk&f 102922 (IC50) | fpl 55712 (IC50) |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 1.58 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 0.51 | |
| Thromboxane-A synthase | Homo sapiens (human) | 10 | |
| Cysteinyl leukotriene receptor 2 | Homo sapiens (human) | 0.51 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 2.255 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banner, BL; Chiu, AM; Cohen, N; Focella, A; Lopresti, RJ; O'Donnell, M; Schaer, B; Todaro, L; Weber, G; Zenchoff, GB | 1 |
| Cieslinksi, LB; Foley, JJ; Kopia, GA; Sarau, HM; Torphy, TJ; Valocik, RE; Wasserman, MA | 1 |
| Jackson, WF | 1 |
| Hay, DW; Muccitelli, RM; Torphy, TJ; Tucker, SS; Wasserman, MA | 1 |
| Gary, RK; Gleason, JG; Nieves, AL; Wasserman, MA; Williams, LS; Woodward, DF | 1 |
| DeVan, JF; Erhard, KF; Gleason, JG; Kirchner, T; McCarthy, ME; Muccitelli, RM; Perchonock, CD; Tucker, SS; Vickery, LM; Wasserman, MA | 1 |
| Clark, MA; Crooke, ST; Gleason, JG; Mong, S; Wu, HL | 1 |
| DeVan, JF; Erhard, KF; Gleason, JG; McCarthy, ME; Muccitelli, RM; Perchonock, CD; Tucker, SS; Uzinskas, I; Vickery, LM; Wasserman, MA | 1 |
8 other study(ies) available for sk&f 102922 and fpl 55712
| Article | Year |
|---|---|
3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists.
Topics: Animals; Benzopyrans; Chemical Phenomena; Chemistry; Chromans; Guinea Pigs; Leukotriene Antagonists; Male; Models, Molecular; Rats; Receptors, Immunologic; Receptors, Leukotriene; Stereoisomerism; Structure-Activity Relationship | 1989 |
Inhibition of leukotriene D4-induced coronary vasoconstriction by leukotriene antagonists in the anesthetized dog.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chromones; Coronary Circulation; Dicarboxylic Acids; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Lipoxygenase Inhibitors; SRS-A; Sulfonamides; Vasoconstriction | 1987 |
Arteriolar oxygen reactivity is inhibited by leukotriene antagonists.
Topics: Animals; Arteries; Arterioles; Chromones; Cricetinae; Dicarboxylic Acids; Epoprostenol; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Mesocricetus; Oxygen; Partial Pressure; SRS-A | 1989 |
Is the guinea pig trachea a good in vitro model of human large and central airways? Comparison on leukotriene-, methacholine-, histamine- and antigen-induced contractions.
Topics: Adult; Animals; Antigens; Borates; Bronchi; Child; Chromones; Dicarboxylic Acids; Female; Guinea Pigs; Histamine; Humans; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Models, Biological; Muscle Contraction; Receptors, Leukotriene; Receptors, Prostaglandin; Serine; SRS-A; Trachea | 1987 |
Characterization of the conjunctival vasopermeability response to leukotrienes and their involvement in immediate hypersensitivity.
Topics: Animals; Antigens; Capillary Permeability; Chromones; Conjunctiva; Dicarboxylic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Hypersensitivity, Immediate; Leukotriene E4; Male; Masoprocol; Ovalbumin; SRS-A; Stereoisomerism; Time Factors | 1988 |
Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists.
Topics: Airway Resistance; Animals; Chemical Phenomena; Chemistry; Chromones; Dicarboxylic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Lung Compliance; Muscle Contraction; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Trachea | 1985 |
Leukotriene D4 receptor-mediated synthesis and release of arachidonic acid metabolites in guinea pig lung: induction of thromboxane and prostacyclin biosynthesis by leukotriene D4.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Chromones; Dicarboxylic Acids; Dose-Response Relationship, Drug; Epoprostenol; Guinea Pigs; Lung; Male; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Thromboxanes | 1986 |
Synthesis and structure-activity relationship studies of a series of 5-aryl-4,6-dithianonanedioic acids and related compounds: a novel class of leukotriene antagonists.
Topics: Alkynes; Animals; Binding, Competitive; Bronchi; Dicarboxylic Acids; Guinea Pigs; Magnetic Resonance Spectroscopy; Muscle Contraction; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Stereoisomerism; Structure-Activity Relationship; Sulfides; Trachea | 1986 |