sk&f 100330-a has been researched along with nipecotic acid in 3 studies
| Studies (sk&f 100330-a) | Trials (sk&f 100330-a) | Recent Studies (post-2010) (sk&f 100330-a) | Studies (nipecotic acid) | Trials (nipecotic acid) | Recent Studies (post-2010) (nipecotic acid) |
|---|---|---|---|---|---|
| 20 | 0 | 0 | 308 | 0 | 43 |
| 20 | 0 | 0 | 15 | 0 | 5 |
| Protein | Taxonomy | sk&f 100330-a (IC50) | nipecotic acid (IC50) |
|---|---|---|---|
| Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (human) | 5.92 | |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | 8.1516 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 8.5114 | |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | 2.3314 | |
| Sodium- and chloride-dependent betaine transporter | Mus musculus (house mouse) | 7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, FE; Bondinell, WE; Dandridge, PA; Frazee, JS; Garvey, E; Girard, GR; Kaiser, C; Ku, TW; Lafferty, JJ; Moonsammy, GI | 1 |
| Faust, MR; Höfner, G; Pabel, J; Wanner, KT | 1 |
| Falch, E; Krogsgaard-Larsen, P; Larsson, OM; Schousboe, A | 1 |
3 other study(ies) available for sk&f 100330-a and nipecotic acid
| Article | Year |
|---|---|
Orally active and potent inhibitors of gamma-aminobutyric acid uptake.
Topics: 4-Aminobutyrate Transaminase; Administration, Oral; Alkylation; Amino Acids; Animals; Brain; Carboxylic Acids; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Stereoisomerism; Synaptosomes | 1985 |
Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.
Topics: Animals; Azetidines; Biological Transport; Cattle; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Structure-Activity Relationship | 2010 |
Kinetic characterization of inhibition of gamma-aminobutyric acid uptake into cultured neurons and astrocytes by 4,4-diphenyl-3-butenyl derivatives of nipecotic acid and guvacine.
Topics: Animals; Anticonvulsants; Astrocytes; Cells, Cultured; Cerebral Cortex; Chemical Phenomena; Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Neurons; Nicotinic Acids; Nipecotic Acids; Proline | 1988 |