sivelestat has been researched along with mocetinostat in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 8 (34.78) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Johno, M; Murakami, K; Nakagaki, T; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M | 1 |
| Akizuki, E; Goto, M; Ichiguchi, O; Matsumura, F; Miyanari, N; Mori, K; Ogawa, M; Yamada, S; Yamaguchi, Y | 1 |
| Harada, N; Johno, M; Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M | 1 |
| Hattori, S; Kaneko, K; Kudoh, I; Ohara, M; Okumura, F; Wiener-Kronish, J; Yamada, H | 1 |
| Matsukawa, A; Matsuura, K; Okamura, H; Tanaka, N; Ujioka, T; Yoshinaga, M | 1 |
| Harada, N; Irie, T; Isobe, H; Liu, W; Murakami, K; Okajima, K | 1 |
| Hagio, T; Kawabata, K; Matsumoto, S; Matsuoka, H; Nakao, S; Ohno, H | 1 |
| Muraguchi, M; Murata, K; Nishisho, T; Ohmoto, Y; Ohsaki, H; Shiba, K; Takeda, E; Taketani, Y; Tonai, T | 1 |
| Ichikawa, H; Naito, Y; Nakamura, Y; Ochiai, J; Sugimoto, N; Yoshida, N; Yoshikawa, T | 1 |
| Abiru, T; Hagio, T; Kawabata, K; Matsumoto, S; Nakao, S; Ohno, H | 1 |
| Harada, N; Mori, M; Okajima, K; Uchiba, M | 1 |
| Hagio, T; Kawabata, K; Matsumoto, S; Matsuoka, S; Nakao, S | 1 |
| Fukuda, I; Kondo, N; Suzuki, Y; Wakayama, F | 1 |
| Funakoshi, Y; Ishizaka, A; Katori, N; Kawabata, K; Kotake, Y; Morisaki, H; Nakamura, N; Suzuki, T; Takeda, J; Yajima, S; Yamada, S | 1 |
| Busuttil, RW; Freitas, MC; Kupiec-Weglinski, JW; Uchida, Y; Zhao, D | 1 |
| Harada, N; Kawai, M; Okajima, K; Takeyama, H | 1 |
| Dimitriadis, F; Kinoshita, Y; Saito, M; Satoh, I; Satoh, K; Shimizu, S; Shomori, K; Tsounapi, P | 1 |
| Miao, QB; Shu, YS; Tao, W; Zhu, YB | 1 |
| Bao, R; Chen, H; Deng, X; Hou, J; Li, J; Liu, Y; Sun, L; Wang, J; Yang, T; Zhang, J; Zhu, X | 1 |
| Fang, QH; Jiang, YW; Yuan, Q | 1 |
| Katakura, K; Ohira, H; Shioya, Y | 1 |
| Chen, L; Gong, H; Ma, P; Tang, A; Wang, H; Wang, S | 1 |
23 other study(ies) available for sivelestat and mocetinostat
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Anticoagulants; Antithrombin III; Capillary Permeability; Chemotaxis, Leukocyte; Disseminated Intravascular Coagulation; Endotoxins; Enzyme Activation; Enzyme Inhibitors; Factor Xa; Fibrin Fibrinogen Degradation Products; Fibrinogen; Glycine; Heparin; Leukocyte Elastase; Leukopenia; Lipopolysaccharides; Lung; Male; Molecular Sequence Data; Pancreatic Elastase; Peroxidase; Protein C; Pulmonary Circulation; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Sulfonamides; Thrombin; Tumor Necrosis Factor-alpha | 1996 |
Neutrophil elastase inhibitor reduces neutrophil chemoattractant production after ischemia-reperfusion in rat liver.
Topics: Animals; Antithrombin III; Aspartate Aminotransferases; Chemokines, CXC; Chemotactic Factors; Drug Synergism; Glycine; Growth Substances; Heparin; Intercellular Signaling Peptides and Proteins; Ischemia; Leukocyte Count; Leukocyte Elastase; Liver; Liver Circulation; Male; Neutrophils; Peroxidase; Rats; Rats, Wistar; Reperfusion; RNA, Messenger; Serine Proteinase Inhibitors; Sulfonamides | 1997 |
Rebamipide attenuates indomethacin-induced gastric mucosal lesion formation by inhibiting activation of leukocytes in rats.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cimetidine; Gastric Mucosa; Glycine; Humans; In Vitro Techniques; Indomethacin; Leukocyte Elastase; Male; Neutrophil Activation; Neutrophils; Peroxidase; Quinolones; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Sulfonamides | 1997 |
Neutrophil elastase inhibitor, ONO-5046, modulates acid-induced lung and systemic injury in rabbits.
Topics: Animals; Bronchoalveolar Lavage Fluid; Glycine; Hemodynamics; Leukocyte Count; Leukocyte Elastase; Neutrophils; Peroxidase; Pneumonia, Aspiration; Rabbits; Serine Proteinase Inhibitors; Sulfonamides | 1997 |
Interleukin-8 as an essential factor in the human chorionic gonadotropin-induced rabbit ovulatory process: interleukin-8 induces neutrophil accumulation and activation in ovulation.
Topics: Animals; Chorionic Gonadotropin; Female; Glycine; Humans; Interleukin-8; Neutrophil Activation; Neutrophils; Ovary; Ovulation; Peroxidase; Rabbits; Serine Proteinase Inhibitors; Sulfonamides | 1998 |
Role of neutrophil elastase in stress-induced gastric mucosal injury in rats.
Topics: Animals; Capillary Permeability; Cephalosporins; Disease Models, Animal; Gastric Mucosa; Glycine; Leukocyte Elastase; Leukopenia; Male; Mechlorethamine; Neutrophils; Peptic Ulcer; Peroxidase; Rats; Rats, Wistar; Restraint, Physical; Serine Proteinase Inhibitors; Specific Pathogen-Free Organisms; Stress, Physiological; Sulfonamides | 1998 |
Inhibition of neutrophil elastase activity attenuates complement-mediated lung injury in the hamster.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Catalase; Complement Activation; Cricetinae; Dose-Response Relationship, Drug; Elapid Venoms; Glycine; Leukocyte Elastase; Lung; Lung Diseases; Male; Mesocricetus; Neutrophils; Peroxidase; Proteins; Serine Proteinase Inhibitors; Sulfonamides; Time Factors | 2001 |
A neutrophil elastase inhibitor (ONO-5046) reduces neurologic damage after spinal cord injury in rats.
Topics: Animals; Blood-Brain Barrier; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Gene Expression; Glycine; Growth Substances; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Interleukin-8; Leukocyte Elastase; Motor Activity; Peroxidase; Rats; Rats, Wistar; Recovery of Function; RNA, Messenger; Serine Proteinase Inhibitors; Spinal Cord; Spinal Cord Injuries; Sulfonamides | 2001 |
Role of elastase and active oxygen species in gastric mucosal injury induced by aspirin administration in Helicobacter pylori-infected Mongolian gerbils.
Topics: Animals; Aspirin; Catalase; Free Radical Scavengers; Gastric Mucosa; Gerbillinae; Glycine; Helicobacter Infections; Helicobacter pylori; Leukocyte Elastase; Male; Peroxidase; Reactive Oxygen Species; Stomach Ulcer; Sulfonamides; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2002 |
Elastase inhibition reduced death associated with acid aspiration-induced lung injury in hamsters.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Hemorrhage; Hydrochloric Acid; In Vitro Techniques; Leukocyte Count; Leukocyte Elastase; Lung; Male; Mesocricetus; Neutrophils; Peroxidase; Pneumonia, Aspiration; Respiratory Insufficiency; Sulfonamides; Survival Analysis | 2004 |
Neutrophil elastase contributes to the development of ischemia-reperfusion-induced liver injury by decreasing endothelial production of prostacyclin in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Permeability; Cephalosporins; Chemokines, CXC; Cyclooxygenase Inhibitors; Endothelium; Enzyme Inhibitors; Epoprostenol; Glycine; Iloprost; Indomethacin; Intercellular Signaling Peptides and Proteins; Leukocyte Elastase; Liver; Liver Circulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides; Transaminases; Vasodilator Agents | 2004 |
Sivelestat, a specific neutrophil elastase inhibitor, prevented phorbol myristate acetate-induced acute lung injury in conscious rabbits.
Topics: Acute Disease; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Glycine; Hemorrhage; Injections, Intravenous; Leukocyte Elastase; Lung; Male; Organ Size; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Proteins; Pulmonary Alveoli; Pulmonary Edema; Rabbits; Respiratory Insufficiency; Sulfonamides; Tetradecanoylphorbol Acetate | 2005 |
Neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury after cardiopulmonary bypass in the rabbit endotoxemia model.
Topics: Animals; Cardiopulmonary Bypass; Glycine; Interleukin-8; Leukocyte Elastase; Lipopolysaccharides; Neutrophils; Peroxidase; Rabbits; Respiratory Distress Syndrome; Sulfonamides | 2007 |
Inhibition of neutrophil elastase attenuates gut mucosal injury evoked by acute alveolar hypoxia in rabbits.
Topics: Acute Disease; Animals; Glycine; HMGB1 Protein; Hypoxia; Intestinal Mucosa; Leukocyte Elastase; Male; Neutrophils; Permeability; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Rabbits; Sulfonamides | 2007 |
The protective function of neutrophil elastase inhibitor in liver ischemia/reperfusion injury.
Topics: Animals; Chemokine CXCL1; DNA Primers; Glycine; Humans; Immunohistochemistry; Inflammation; Interleukin-6; Leukocyte Elastase; Liver; Male; Mice; Mice, Inbred C57BL; Neutrophils; Peroxidase; Polymerase Chain Reaction; Proteinase Inhibitory Proteins, Secretory; Reperfusion Injury; RNA; Sulfonamides; Tumor Necrosis Factor-alpha | 2010 |
Neutrophil elastase contributes to the development of ischemia/reperfusion-induced liver injury by decreasing the production of insulin-like growth factor-I in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcitonin Gene-Related Peptide; Cephalosporins; Glycine; Hepatic Artery; Iloprost; Indomethacin; Insulin-Like Growth Factor I; Leukocyte Elastase; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Peroxidase; Platelet Aggregation Inhibitors; Portal Vein; Rats; Rats, Wistar; Reperfusion Injury; Serine Proteinase Inhibitors; Sulfonamides | 2010 |
Protective effect of sivelestat, a neutrophil elastase inhibitor, on ipsilateral and contralateral testes after unilateral testicular ischaemia-reperfusion injury in rats.
Topics: Animals; Glycine; HSP70 Heat-Shock Proteins; Male; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfonamides; Testis; Testosterone | 2011 |
Inhaled neutrophil elastase inhibitor reduces oleic acid-induced acute lung injury in rats.
Topics: Acute Lung Injury; Administration, Inhalation; Albumins; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Cell Count; Extravascular Lung Water; Female; Glycine; Injections, Intravenous; Leukocyte Count; Leukocyte Elastase; Oleic Acid; Ovalbumin; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Sulfonamides; Survival Analysis | 2012 |
Combined effects of a neutrophil elastase inhibitor (sivelestat sodium) and a free radical scavenger (edaravone) on lipopolysaccharide-induced acute lung injury in rats.
Topics: Acute Lung Injury; Animals; Antipyrine; Drug Combinations; Edaravone; Free Radical Scavengers; Glycine; Interleukin-6; Lipopolysaccharides; Male; Malondialdehyde; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Rats; Rats, Sprague-Dawley; Sulfonamides; Tumor Necrosis Factor-alpha | 2012 |
Improving effect of Sivelestat on lipopolysaccharide-induced lung injury in rats.
Topics: Acute Lung Injury; Animals; Endothelial Cells; Glycine; Intercellular Adhesion Molecule-1; Leukocyte Elastase; Lipopolysaccharides; Lung; Male; Neutrophil Infiltration; Peroxidase; Proteinase Inhibitory Proteins, Secretory; Pulmonary Edema; Rats; Rats, Wistar; Sepsis; Serine Proteinase Inhibitors; Sulfonamides; Transcription Factor RelA | 2014 |
Neutrophil elastase inhibitor suppresses IL-17 based inflammation of murine experimental colitis.
Topics: Animals; Chemokines; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Female; Glycine; Interleukin-17; Leukocyte Elastase; Mice; Mice, Inbred BALB C; Peroxidase; Proteinase Inhibitory Proteins, Secretory; RNA, Messenger; Sulfonamides | 2014 |
Combined effects of sivelestat and resveratrol on severe acute pancreatitis-associated lung injury in rats.
Topics: Acute Disease; Amylases; Animals; Arterial Pressure; Bronchoalveolar Lavage Fluid; Glycine; Interleukin-6; Leukocyte Elastase; Lung; Lung Injury; Male; Oxygen; Pancreatitis; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Sulfonamides | 2014 |