sivelestat has been researched along with hydrochloric acid in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimoto, J; Fukushima, J; Kudoh, I; Miyazaki, H; Ohara, M; Okumura, F; Tazawa, T; Yamada, H | 1 |
| Abiru, T; Hagio, T; Kawabata, K; Matsumoto, S; Nakao, S; Ohno, H | 1 |
| Fujimoto, K; Jian, MY; Koizumi, T; Kubo, K; Tsushima, K | 1 |
| Koizumi, T; Kubo, K; Tsushima, K; Yoshikawa, S | 1 |
4 other study(ies) available for sivelestat and hydrochloric acid
| Article | Year |
|---|---|
[Pretreatment of acid-induced lung injury with specific neutrophil elastase inhibitor ONO-5046 did not exasperate the subsequent bacterial lung infection by Pseudomonas aeruginosa].
Topics: Animals; Disease Models, Animal; Glycine; Hydrochloric Acid; Leukocyte Elastase; Male; Pneumonia, Aspiration; Pneumonia, Bacterial; Pseudomonas Infections; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Sulfonamides | 2000 |
Elastase inhibition reduced death associated with acid aspiration-induced lung injury in hamsters.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycine; Hemorrhage; Hydrochloric Acid; In Vitro Techniques; Leukocyte Count; Leukocyte Elastase; Lung; Male; Mesocricetus; Neutrophils; Peroxidase; Pneumonia, Aspiration; Respiratory Insufficiency; Sulfonamides; Survival Analysis | 2004 |
Effects of granulocyte colony-stimulating factor (G-CSF) and neutrophil elastase inhibitor (ONO-5046) on acid-induced lung injury in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Glycine; Granulocyte Colony-Stimulating Factor; Hydrochloric Acid; Leukocyte Elastase; Lung; Lung Injury; Male; Pneumonia, Aspiration; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors | 2004 |
Effects of a synthetic protease inhibitor (gabexate mesilate) and a neutrophil elastase inhibitor (sivelestat sodium) on acid-induced lung injury in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Gabexate; Glycine; Hydrochloric Acid; Leukocyte Count; Lung Injury; Male; Neutrophils; Protease Inhibitors; Proteinase Inhibitory Proteins, Secretory; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium; Sulfonamides | 2010 |