sirolimus and 2-methacryloyloxyethyl-phosphorylcholine

sirolimus has been researched along with 2-methacryloyloxyethyl-phosphorylcholine* in 1 studies

Other Studies

1 other study(ies) available for sirolimus and 2-methacryloyloxyethyl-phosphorylcholine

Article	Year
[Pilot study of a cell membrane like biomimetic drug-eluting coronary stent]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2007, Volume: 24, Issue:3 A novel bioinspired phospholipid copolymer has been synthesized by the radical polymerization of poly2-Methacryloyloxyethylphosphorylcholine (MPC), stearyl methacrylate (SMA), hydroxypropyl methacrylate (HPMA) and trimethoxysilylpropyl methacrylate (TSMA). Contact angle results indicated that the coating surface rearranged to get a more hydrophilic surface at the polymer/water interface. The membrane mimic phosphorylcholine coating surface could resist the platelet adhesion and prolong plasma recalcification time significantly. Rapamycin was used as model drugs to prepare drug-eluting coating. The animal experiments showed that this novel drug-eluting stent could effectively prevent the phenomena of restenosis. Topics: Angioplasty, Balloon, Coronary; Animals; Coated Materials, Biocompatible; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Materials Testing; Methacrylates; Phosphorylcholine; Pilot Projects; Polymers; Prosthesis Design; Random Allocation; Sirolimus; Swine; Swine, Miniature	2007

Article

Year

[Pilot study of a cell membrane like biomimetic drug-eluting coronary stent].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2007, Volume: 24, Issue:3

A novel bioinspired phospholipid copolymer has been synthesized by the radical polymerization of poly2-Methacryloyloxyethylphosphorylcholine (MPC), stearyl methacrylate (SMA), hydroxypropyl methacrylate (HPMA) and trimethoxysilylpropyl methacrylate (TSMA). Contact angle results indicated that the coating surface rearranged to get a more hydrophilic surface at the polymer/water interface. The membrane mimic phosphorylcholine coating surface could resist the platelet adhesion and prolong plasma recalcification time significantly. Rapamycin was used as model drugs to prepare drug-eluting coating. The animal experiments showed that this novel drug-eluting stent could effectively prevent the phenomena of restenosis.

Topics: Angioplasty, Balloon, Coronary; Animals; Coated Materials, Biocompatible; Coronary Restenosis; Drug-Eluting Stents; Female; Humans; Male; Materials Testing; Methacrylates; Phosphorylcholine; Pilot Projects; Polymers; Prosthesis Design; Random Allocation; Sirolimus; Swine; Swine, Miniature

2007