sipatrigine has been researched along with lamotrigine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Clutterbuck, LA; Gane, PJ; Garthwaite, J; Lancaster, B; Posada, CG; Riddall, DR; Selwood, DL; Visintin, C | 1 |
| Al-Izki, S; Baker, D; Browne, L; Chan, AW; Clutterbuck, L; Garthwaite, J; Lidster, K; Posada, C; Riddall, D; Selwood, DL | 1 |
| Meldrum, BS; Smith, SE | 1 |
| Meldrum, BS | 1 |
| Obrenovitch, TP | 1 |
| Batchelor, AM; Brown, G; Garthwaite, G; Garthwaite, J; Goodwin, DA | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Giacomini, P; Hainsworth, AH; Leach, MJ; Marfia, GA; Saulle, E; Spadoni, F; Stefani, A | 1 |
| Brown, J; Catterall, WA; Clare, JJ; Scheuer, T; Sharp, EM; Yarov-Yarovoy, V | 1 |
| Bernardi, G; Hainsworth, AH; Lavaroni, F; Spadoni, F; Stefani, A | 1 |
| Ahring, PK; Christophersen, P; Gersdorff Korsgaard, MP; Olesen, SP | 1 |
| Bernardi, G; Caputi, L; Hainsworth, AH; Lavaroni, F; Martella, G; Mercuri, NB; Spadoni, F; Stefani, A | 1 |
| Catterall, WA; Clare, JJ; Liu, G; Nobbs, M; Scheuer, T; Yarov-Yarovoy, V | 1 |
| Hainsworth, AH; McNaughton, NC; Pereverzev, A; Randall, AD; Schneider, T | 1 |
| Tikhonov, DB; Zhorov, BS | 1 |
3 review(s) available for sipatrigine and lamotrigine
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
The role of glutamate in epilepsy and other CNS disorders.
Topics: Animals; Central Nervous System Diseases; Epilepsy; Glutamic Acid; Humans; Lamotrigine; Mice; N-Methylaspartate; Parkinson Disease; Piperazines; Pyrimidines; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines | 1994 |
Sodium and potassium channel modulators: their role in neuroprotection.
Topics: Animals; Benzeneacetamides; Cell Survival; Disease Models, Animal; Lamotrigine; Neurons; Neuroprotective Agents; Piperazines; Piperidines; Potassium Channels; Pyrimidines; Riluzole; Sodium Channels; Thiazoles; Triazines | 1997 |
12 other study(ies) available for sipatrigine and lamotrigine
| Article | Year |
|---|---|
Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Design; Electrophysiological Phenomena; Hippocampus; Indazoles; Male; Neurons; Neuroprotective Agents; Protein Isoforms; Quantitative Structure-Activity Relationship; Rats; Rats, Wistar; Sodium Channel Blockers; Sodium Channels | 2009 |
Imidazol-1-ylethylindazole voltage-gated sodium channel ligands are neuroprotective during optic neuritis in a mouse model of multiple sclerosis.
Topics: Animals; Disease Models, Animal; Female; Humans; Imidazoles; Lymph Nodes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiple Sclerosis; Neuroprotective Agents; Optic Neuritis; Retinal Ganglion Cells; Voltage-Gated Sodium Channels | 2014 |
Cerebroprotective effect of lamotrigine after focal ischemia in rats.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Drug Administration Schedule; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Lamotrigine; Male; Piperazines; Pyrimidines; Rats; Rats, Inbred F344; Sodium Channels; Triazines | 1995 |
Mechanisms of ischaemic damage to central white matter axons: a quantitative histological analysis using rat optic nerve.
Topics: Animals; Axons; Glucose; Hypoxia; In Vitro Techniques; Ischemia; Lamotrigine; Microscopy, Electron; Neuroprotective Agents; Optic Nerve; Piperazines; Pyrimidines; Rats; Rats, Wistar; Sodium Channel Blockers; Triazines | 1999 |
Electrophysiology of sipatrigine: a lamotrigine derivative exhibiting neuroprotective effects.
Topics: Action Potentials; Animals; Anticonvulsants; Brain Chemistry; Calcium Channels; Corpus Striatum; Epilepsy; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lamotrigine; Male; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Piperazines; Pyrimidines; Rats; Rats, Wistar; Sodium; Stroke; Tetrodotoxin; Triazines | 2000 |
Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.
Topics: Amino Acid Substitution; Anesthetics, Local; Animals; Anticonvulsants; Binding Sites; Brain; Electrophysiology; Etidocaine; Ion Channel Gating; Lamotrigine; Membrane Proteins; Oocytes; Patch-Clamp Techniques; Piperazines; Point Mutation; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Rats; Sodium Channel Blockers; Sodium Channels; Thermodynamics; Triazines; Xenopus laevis | 2001 |
Effects of extracellular pH on the interaction of sipatrigine and lamotrigine with high-voltage-activated (HVA) calcium channels in dissociated neurones of rat cortex.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Hydrogen-Ion Concentration; Lamotrigine; Male; Neocortex; Neurons; Neurotransmitter Uptake Inhibitors; Piperazines; Pyrimidines; Rats; Rats, Wistar; Triazines | 2001 |
Identification of a novel voltage-gated Na+ channel rNa(v)1.5a in the rat hippocampal progenitor stem cell line HiB5.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Cell Line; Cell Line, Transformed; Electrophysiology; Embryo, Mammalian; Hippocampus; Ion Channel Gating; Lamotrigine; Molecular Sequence Data; NAV1.5 Voltage-Gated Sodium Channel; Piperazines; Pyrimidines; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sodium Channels; Stem Cells; Tetrodotoxin; Triazines | 2001 |
Lamotrigine derivatives and riluzole inhibit INa,P in cortical neurons.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsy; Lamotrigine; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Piperazines; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Riluzole; Sodium; Sodium Channel Blockers; Sodium Channels; Triazines | 2002 |
Differential interactions of lamotrigine and related drugs with transmembrane segment IVS6 of voltage-gated sodium channels.
Topics: Alanine; Animals; Binding Sites; Calcium Channel Blockers; Dose-Response Relationship, Drug; Ion Channel Gating; Kinetics; Lamotrigine; Membrane Proteins; Mutagenesis, Site-Directed; Neurotransmitter Uptake Inhibitors; Oocytes; Patch-Clamp Techniques; Piperazines; Protein Structure, Tertiary; Pyrimidines; Recombinant Proteins; Sodium Channel Agonists; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship; Time Factors; Triazines; Xenopus | 2003 |
Actions of sipatrigine, 202W92 and lamotrigine on R-type and T-type Ca2+ channel currents.
Topics: Calcium Channel Blockers; Calcium Channels; Calcium Channels, R-Type; Calcium Channels, T-Type; Cation Transport Proteins; Cells, Cultured; Humans; Lamotrigine; Patch-Clamp Techniques; Piperazines; Pyrimidines; Triazines | 2003 |
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines | 2017 |