sinitrodil has been researched along with niacinamide in 2 studies
*Niacinamide: An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [MeSH]
*Niacinamide: An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [MeSH]
| Studies (sinitrodil) | Trials (sinitrodil) | Recent Studies (post-2010) (sinitrodil) | Studies (niacinamide) | Trials (niacinamide) | Recent Studies (post-2010) (niacinamide) |
|---|---|---|---|---|---|
| 23 | 5 | 0 | 13,381 | 1,097 | 5,797 |
| Protein | Taxonomy | sinitrodil (IC50) | niacinamide (IC50) |
|---|---|---|---|
| Chain A, NAD-dependent deacetylase | Thermotoga maritima | 1000 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 3.3 | |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | 2.9 | |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Homo sapiens (human) | 8.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benedini, F; Bertolini, G; Cereda, R; Donà, G; Gromo, G; Levi, S; Mizrahi, J; Sala, A | 1 |
| Bergamaschi, M; Gromo, G; Mizrahi, J; Nonaka, K; Ueno, A | 1 |
2 other study(ies) available for sinitrodil and niacinamide
| Article | Year |
|---|---|
New antianginal nitro esters with reduced hypotensive activity. Synthesis and pharmacological evaluation of 3-[(nitrooxy)alkyl]-2H-1,3-benzoxazin-4(3H)-ones.
Topics: Angina Pectoris; Animals; Benzoxazines; Blood Pressure; Hemodynamics; Hypotension; In Vitro Techniques; Ischemia; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Rabbits; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Vasodilator Agents | 1995 |
Effect of the new nitrate ester ITF 296 on coronary and systemic hemodynamics in the conscious dog: comparison with nitroglycerin and nicorandil.
Topics: Animals; Benzoxazines; Coronary Circulation; Coronary Vessels; Dogs; Female; Hemodynamics; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitrates; Nitroglycerin; Oxazines; Vasodilator Agents | 1995 |