Page last updated: 2024-09-04

singlet oxygen and hypericin

singlet oxygen has been researched along with hypericin in 20 studies

Compound Research Comparison

Studies
(singlet oxygen)
Trials
(singlet oxygen)
Recent Studies (post-2010)
(singlet oxygen)
Studies
(hypericin)
Trials
(hypericin)
Recent Studies (post-2010) (hypericin)
3,87042,32298231380

Protein Interaction Comparison

ProteinTaxonomysinglet oxygen (IC50)hypericin (IC50)
Cytochrome P450 3A4Homo sapiens (human)8.7
Corticotropin-releasing factor receptor 1Homo sapiens (human)0.3
Cystathionine beta-synthaseHomo sapiens (human)3.1
Alpha-synucleinHomo sapiens (human)7.5
Glutathione reductaseSaccharomyces cerevisiae S288C3.67
Integrase Human immunodeficiency virus 110
Cysteine protease ATG4BHomo sapiens (human)8.9

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (25.00)18.2507
2000's7 (35.00)29.6817
2010's6 (30.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
MacGill, RS; Miller, GC; Pardini, RS; Thomas, C1
Grossweiner, LI; Jones, LR; Senthil, K; Senthil, V1
Diwu, Z; Lown, JW1
Anderson, JL; Ehrenberg, B; Foote, CS1
Carpenter, S; English, DS; Park, J; Petrich, JW; Wannemuehler, Y1
Ehrenberg, B; Freeman, D; Mazur, Y; Roslaniec, M; Weitman, H1
Kanofsky, JR; Sima, PD1
Falk, H; Hohenthanner, K; Obermüller, RA1
Carpenter, S; Kesavan, S; Kraus, GA; Park, J; Petrich, JW; Wen, J; Wills, NJ1
Ji, HF; Shen, L; Zhang, HY1
Breitenbach, T; Gbur, P; Hatz, S; Kuimova, MK; Lambert, JD; Ogilby, PR; Pedersen, BW; Poulsen, L; Schack, NB1
Agostinis, P; de Witte, PA; Falk, H; Lackner, B; Roelants, M; Van Poppel, H; Waser, M1
Fedoročko, P; Ferenc, P; Fulton, BL; Hrčková, G; Koval', J; Mikeš, J; Solár, P; Solárová, Z1
Agut, M; Andres-Ciriano, E; Aspiroz, C; Gilaberte, Y; López-Chicón, P; Nonell, S; Paz-Cristobal, MP; Rezusta, A; Royo-Cañas, M1
Andrade, GP; Creczynski-Pasa, TB; Lima, AM; Monteiro, FB; Perussi, JR; Pizzol, CD; Ribeiro, AO1
Barras, A; Boukherroub, R; Boussekey, L; Courtade, E1
Dehez, F; Gattuso, H; Marazzi, M; Monari, A1
Cerchiaro, G; de Andrade, GP; Manieri, TM; Nunes, EA; Ribeiro, AO; Viana, GM1
Li, B; Li, F; Lu, C; Teng, X1
Angulo-Pachón, CA; Bedrina, B; Falomir, E; Galindo, F; Marín, MJ; Miravet, JF; Torres-Martínez, A1

Other Studies

20 other study(ies) available for singlet oxygen and hypericin

ArticleYear
Photoactivation of hypericin generates singlet oxygen in mitochondria and inhibits succinoxidase.
    Photochemistry and photobiology, 1992, Volume: 55, Issue:1

    Topics: Animals; Anthracenes; Cattle; Light; Mitochondria, Heart; Oxidoreductases; Oxygen; Perylene; Radiation-Sensitizing Agents; Singlet Oxygen

1992
Hypericin photosensitization in aqueous model systems.
    Photochemistry and photobiology, 1994, Volume: 59, Issue:1

    Topics: Animals; Anthracenes; Cattle; Erythrocyte Membrane; Erythrocytes; Hemolysis; In Vitro Techniques; Liposomes; Oxygen; Perylene; Photosensitizing Agents; Singlet Oxygen; Water

1994
Photosensitization with anticancer agents. 17. EPR studies of photodynamic action of hypericin: formation of semiquinone radical and activated oxygen species on illumination.
    Free radical biology & medicine, 1993, Volume: 14, Issue:2

    Topics: Anthracenes; Antineoplastic Agents; Benzoquinones; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Light; Oxygen; Perylene; Photosensitizing Agents; Piperidones; Reactive Oxygen Species; Singlet Oxygen; Spin Labels; Superoxides; Triacetoneamine-N-Oxyl

1993
Kinetics and yield of singlet oxygen photosensitized by hypericin in organic and biological media.
    Photochemistry and photobiology, 1998, Volume: 68, Issue:2

    Topics: Anthracenes; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liposomes; Oxygen; Perylene; Photochemistry; Photosensitizing Agents; Singlet Oxygen; Solutions; Spectrophotometry

1998
The role of oxygen in the antiviral activity of hypericin and hypocrellin.
    Photochemistry and photobiology, 1998, Volume: 68, Issue:4

    Topics: Adenosine Triphosphate; Animals; Anthracenes; Antiviral Agents; Horses; Infectious Anemia Virus, Equine; Light; Luminescent Measurements; Microbial Sensitivity Tests; Oxygen; Perylene; Phenol; Photochemistry; Quinones; Singlet Oxygen

1998
Liposome binding constants and singlet oxygen quantum yields of hypericin, tetrahydroxy helianthrone and their derivatives: studies in organic solutions and in liposomes.
    Journal of photochemistry and photobiology. B, Biology, 2000, Volume: 57, Issue:2-3

    Topics: Anthracenes; Hematoporphyrin Derivative; Liposomes; Mass Spectrometry; Methanol; Oxygen; Perylene; Phosphatidylcholines; Rose Bengal; Singlet Oxygen; Solutions

2000
Girard's reagent P derivative of beta-Apo-8'-carotenal: a potent photoprotective agent.
    Photochemistry and photobiology, 2001, Volume: 73, Issue:4

    Topics: Anthracenes; Carotenoids; Chromatography, High Pressure Liquid; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Oxygen; Perylene; Photochemistry; Photosensitizing Agents; Porphyrins; Protoporphyrins; Singlet Oxygen; Tumor Cells, Cultured; Vitamin A

2001
Toward hypericin-derived potential photodynamic therapy agents.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:2

    Topics: Anthracenes; In Vitro Techniques; Magnetic Resonance Spectroscopy; Oxygen; Perylene; Photochemistry; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen; Superoxides

2001
Tumor cell toxicity of hypericin and related analogs.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:2

    Topics: Anthracenes; Antineoplastic Agents; Humans; Oxygen; Perylene; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen; Tumor Cells, Cultured

2001
Anion of hypericin is crucial to understanding the photosensitive features of the pigment.
    Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5

    Topics: Anions; Anthracenes; Electrons; Molecular Structure; Perylene; Phenol; Photochemotherapy; Photosensitizing Agents; Pigments, Biological; Quinones; Singlet Oxygen

2006
Photosensitized production of singlet oxygen: spatially-resolved optical studies in single cells.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2009, Volume: 8, Issue:4

    Topics: Anthracenes; HeLa Cells; Humans; Luminescent Measurements; Microscopy, Fluorescence; Neurons; Perylene; Photons; Photosensitizing Agents; Singlet Oxygen

2009
In vitro study of the photocytotoxicity of bathochromically-shifted hypericin derivatives.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2009, Volume: 8, Issue:6

    Topics: Absorption; Animals; Anthracenes; Biological Transport; Cell Line, Tumor; Cell Proliferation; Humans; Intracellular Space; Light; Perylene; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen; Spectrometry, Fluorescence

2009
Photoactivated hypericin induces downregulation of HER2 gene expression.
    Radiation research, 2011, Volume: 175, Issue:1

    Topics: Anthracenes; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Female; Genes, erbB-2; Humans; Perylene; Photochemotherapy; Reactive Oxygen Species; Receptor, ErbB-2; Singlet Oxygen

2011
On the mechanism of Candida spp. photoinactivation by hypericin.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012, Volume: 11, Issue:6

    Topics: Anthracenes; Benzoquinones; Candida; Candida albicans; Hydrogen Peroxide; Kinetics; Light; Microscopy, Fluorescence; Perylene; Radiation-Sensitizing Agents; Singlet Oxygen

2012
Hypericin encapsulated in solid lipid nanoparticles: phototoxicity and photodynamic efficiency.
    Journal of photochemistry and photobiology. B, Biology, 2013, Aug-05, Volume: 125

    Topics: Animals; Anthracenes; Benzofurans; Cell Line, Tumor; Cell Survival; Humans; Light; Lipids; Mice; Nanoparticles; Perylene; Photochemotherapy; Radiation-Sensitizing Agents; Singlet Oxygen; Uric Acid

2013
Hypericin-loaded lipid nanocapsules for photodynamic cancer therapy in vitro.
    Nanoscale, 2013, Nov-07, Volume: 5, Issue:21

    Topics: Anthracenes; Cell Line; Cell Survival; Drug Carriers; HeLa Cells; Humans; Hypericum; Light; Lipids; Microscopy, Video; Nanocapsules; Neoplasms; Particle Size; Perylene; Photochemotherapy; Photosensitizing Agents; Singlet Oxygen; Spectrophotometry, Ultraviolet

2013
Deciphering the photosensitization mechanisms of hypericin towards biological membranes.
    Physical chemistry chemical physics : PCCP, 2017, Aug-30, Volume: 19, Issue:34

    Topics: Anthracenes; Light; Lipid Bilayers; Molecular Dynamics Simulation; Perylene; Quantum Theory; Singlet Oxygen

2017
Comparative in vitro study of photodynamic activity of hypericin and hypericinates in MCF-7 cells.
    Journal of photochemistry and photobiology. B, Biology, 2017, Volume: 175

    Topics: Anthracenes; Apoptosis; Cell Nucleus; Cell Survival; Humans; Light; MCF-7 Cells; Microscopy, Fluorescence; Mitochondria; Perylene; Photosensitizing Agents; Singlet Oxygen

2017
Carbon dot-assisted luminescence of singlet oxygen: the generation dynamics but not the cumulative amount of singlet oxygen is responsible for the photodynamic therapy efficacy.
    Nanoscale horizons, 2020, 06-01, Volume: 5, Issue:6

    Topics: Animals; Anthracenes; Antineoplastic Agents; Carbon; Female; HeLa Cells; Humans; Imidazoles; Luminescence; Luminescent Agents; Methylene Blue; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Perylene; Photochemotherapy; Photosensitizing Agents; Quantum Dots; Quinones; Singlet Oxygen

2020
Non-Polymeric Nanogels as Versatile Nanocarriers: Intracellular Transport of the Photosensitizers Rose Bengal and Hypericin for Photodynamic Therapy.
    ACS applied bio materials, 2021, 04-19, Volume: 4, Issue:4

    Topics: Anthracenes; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Light; Microscopy, Confocal; Nanogels; Perylene; Photochemotherapy; Photosensitizing Agents; Rose Bengal; Singlet Oxygen

2021