Page last updated: 2024-09-04

singlet oxygen and guanine

singlet oxygen has been researched along with guanine in 35 studies

Compound Research Comparison

Studies
(singlet oxygen)
Trials
(singlet oxygen)
Recent Studies (post-2010)
(singlet oxygen)
Studies
(guanine)
Trials
(guanine)
Recent Studies (post-2010) (guanine)
3,87042,32216,2788224,809

Protein Interaction Comparison

ProteinTaxonomysinglet oxygen (IC50)guanine (IC50)
Purine nucleoside phosphorylaseHomo sapiens (human)5

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.43)18.7374
1990's5 (14.29)18.2507
2000's9 (25.71)29.6817
2010's15 (42.86)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Epe, B1
Kelly, JM; McConnell, DJ; OhUigin, C; van der Putten, WJ1
Aiba, H; Inoue, S; Kawanishi, S; Sano, S1
Dahl, TA; Hartman, PE; Midden, WR1
Berger, M; Cadet, J; Decarroz, C; Ginot, YM; van Lier, JE; Vigny, P; Wagner, JR1
Joenje, H; Lafleur, MV; Lutgerink, JT; Retèl, J; van den Akker, E1
De Oliveira, RC; Di Mascio, P; Menck, CF; Ribeiro, DT1
Berg, K; Kvam, E; Steen, HB1
Floyd, RA; Maidt, ML; Phillips, JR; Price, S; Pye, Q; Schneider, JE1
Thompson, M; Woodbury, NW1
Hiraku, Y; Kawanishi, S1
Kawanishi, S; Murakami, K; Oikawa, S1
Cadet, J; Di Mascio, P; Martinez, GR; Medeiros, MH; Ravanat, JL1
Hirakawa, K; Kawanishi, S; Matsumoto, J; Shiragami, T; Yasuda, M1
Hirakawa, K; Hirano, T; Kawanishi, S1
Hirakawa, K; Hirano, T; Kawanishi, S; Segawa, H1
Burrows, CJ; Muller, JG; Xu, X; Ye, Y1
Barton, JK; Jackson, BA1
Cadet, J; Douki, T1
Cui, L; Dedon, PC; Prestwich, EG; Taghizadeh, K; Tannenbaum, SR; Wishnok, JS; Ye, W1
Su, H; Yu, Y; Zhao, H; Zou, X1
Butler, JS; Farrer, NJ; Habtemariam, A; Li, H; McQuitty, RJ; Sadler, PJ; Wang, F; Zhao, Y1
Joshi, PC; Keane, TC; Li, HH; Merchant, M1
Dumont, E; Grüber, R; Monari, A1
An, N; Burrows, CJ; Fleming, AM; White, HS1
An, J; An, T; Li, G; Nie, X1
Di, C; Gan, L; Si, J; Wang, Y; Xie, Y; Zhang, H; Zhou, R; Zhou, X1
Liu, J; Lu, W1
Liu, J; Lu, W; Teng, H1
Aranda, J; Bignon, E; Dumont, E; Grüber, R; Morell, C; Ravanat, JL; Tuñón, I1
Burrows, CJ; Munk, BH; Schlegel, HB; Thapa, B1
Liu, J; Lu, W; Sun, Y; Zhou, W1
Barnes, RP; Bruchez, MP; Fouquerel, E; Opresko, PL; Uttam, S; Watkins, SC1
Dumont, E; Ravanat, JL1
Burrows, CJ; Chabot, MB; Fleming, AM1

Reviews

4 review(s) available for singlet oxygen and guanine

ArticleYear
Genotoxicity of singlet oxygen.
    Chemico-biological interactions, 1991, Volume: 80, Issue:3

    Topics: Animals; Carcinogenicity Tests; DNA Damage; Free Radicals; Guanine; Humans; Mutation; Oxygen; Risk Factors; Singlet Oxygen

1991
Photosensitized reactions of nucleic acids.
    Biochimie, 1986, Volume: 68, Issue:6

    Topics: 4-Aminobenzoic Acid; Animals; Antineoplastic Agents; Bacillus subtilis; Bromouracil; Chemical Phenomena; Chemistry; Daunorubicin; DNA; DNA Repair; DNA, Bacterial; Doxorubicin; Escherichia coli; Free Radicals; Guanine; Hematoporphyrins; Humans; Light; Nucleosides; Oxidation-Reduction; Oxygen; Photochemistry; Pyrimidine Dimers; Pyrimidines; Rose Bengal; Singlet Oxygen; Ultraviolet Rays; Uridine; Urocanic Acid; Vitamin K

1986
Sequence-specific DNA damage induced by UVA radiation in the presence of endogenous and exogenous photosensitizers.
    Current problems in dermatology, 2001, Volume: 29

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Infective Agents; Carcinogens; Cell Transformation, Neoplastic; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Fluoroquinolones; Guanine; Humans; Models, Chemical; Mutagenesis; Nalidixic Acid; Neoplasms, Radiation-Induced; Oxidation-Reduction; Oxygen; Pteridines; Pterins; Quinolones; Radiation-Sensitizing Agents; Singlet Oxygen; Skin Neoplasms; Sunlight; Superoxides; Ultraviolet Rays

2001
Reactivity of Singlet Oxygen with DNA, an Update.
    Photochemistry and photobiology, 2022, Volume: 98, Issue:3

    Topics: DNA; Guanine; Oxidation-Reduction; Oxygen; Reactive Oxygen Species; Singlet Oxygen

2022

Other Studies

31 other study(ies) available for singlet oxygen and guanine

ArticleYear
Methylene blue photosensitised strand cleavage of DNA: effects of dye binding and oxygen.
    Nucleic acids research, 1987, Sep-25, Volume: 15, Issue:18

    Topics: DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Guanine; Hydrolysis; Intercalating Agents; Magnesium; Methylene Blue; Nucleic Acid Conformation; Osmolar Concentration; Oxygen; Photochemistry; Radiation-Sensitizing Agents; Singlet Oxygen

1987
Photodynamic guanine modification by hematoporphyrin is specific for single-stranded DNA with singlet oxygen as a mediator.
    The Journal of biological chemistry, 1986, May-05, Volume: 261, Issue:13

    Topics: DNA Restriction Enzymes; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanine; Hematoporphyrins; Oxygen; Photochemistry; Plasmids; Singlet Oxygen; Spin Labels

1986
Pure exogenous singlet oxygen: nonmutagenicity in bacteria.
    Mutation research, 1988, Volume: 201, Issue:1

    Topics: Azaguanine; Base Composition; DNA Repair; DNA Replication; Drug Resistance, Microbial; Guanine; Histidine; Mutation; Oxygen; Photochemistry; Salmonella typhimurium; Singlet Oxygen

1988
The formation of one-G deletions as a consequence of single-oxygen-induced DNA damage.
    Mutation research, 1994, Aug-01, Volume: 309, Issue:1

    Topics: Bacteriophage M13; Base Sequence; DNA Damage; DNA Mutational Analysis; DNA, Viral; Escherichia coli; Guanine; Molecular Sequence Data; Mutagens; Naphthols; Oxygen; Point Mutation; Sequence Deletion; Singlet Oxygen

1994
Singlet oxygen induces predominantly G to T transversions on a single-stranded shuttle vector replicated in monkey cells.
    Free radical research, 1994, Volume: 21, Issue:2

    Topics: Animals; Cell Line; DNA Damage; Escherichia coli; Genetic Vectors; Guanine; Haplorhini; Mutagenesis; Oxygen; Plasmids; Singlet Oxygen; Thymine; Transfection

1994
Characterization of singlet oxygen-induced guanine residue damage after photochemical treatment of free nucleosides and DNA.
    Biochimica et biophysica acta, 1994, Jan-18, Volume: 1217, Issue:1

    Topics: Deoxyguanosine; DNA; Free Radicals; Guanine; Methylene Blue; Nucleosides; Oxygen; Photochemistry; Porphyrins; Singlet Oxygen

1994
Methylene blue and rose bengal photoinactivation of RNA bacteriophages: comparative studies of 8-oxoguanine formation in isolated RNA.
    Archives of biochemistry and biophysics, 1993, Feb-15, Volume: 301, Issue:1

    Topics: Centrifugation, Density Gradient; Guanine; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Light; Methylene Blue; Oxygen; Photochemistry; RNA Phages; RNA, Viral; Rose Bengal; Singlet Oxygen; Temperature

1993
Fluorescent and photochemical properties of a single zinc finger conjugated to a fluorescent DNA-binding probe.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Base Sequence; Benzothiazoles; Chromatography, High Pressure Liquid; DNA; DNA Footprinting; Fluorescence Polarization; Fluorescent Dyes; Guanine; Intercalating Agents; Light; Molecular Probes; Oxygen; Peptide Fragments; Photolysis; Quinolines; Receptors, Estrogen; Receptors, Glucocorticoid; Response Elements; Sequence Deletion; Singlet Oxygen; Substrate Specificity; Thermodynamics; Thiazoles; Titrimetry; Zinc Fingers

2000
Oxidative damage to cellular and isolated DNA by homocysteine: implications for carcinogenesis.
    Oncogene, 2003, Jun-05, Volume: 22, Issue:23

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Copper; Cysteine; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Guanine; HL-60 Cells; Homocysteine; Humans; Luminescent Measurements; Oxidative Stress; Phosphorus Radioisotopes; Proto-Oncogene Mas; Pyrenes; Singlet Oxygen; Thymine; Thymus Gland

2003
Mechanistic aspects of the oxidation of DNA constituents mediated by singlet molecular oxygen.
    Archives of biochemistry and biophysics, 2004, Mar-01, Volume: 423, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA; Guanine; Oxidation-Reduction; Singlet Oxygen

2004
Guanine-specific DNA damage photosensitized by the dihydroxo(tetraphenylporphyrinato)antimony(V) complex.
    Journal of photochemistry and photobiology. B, Biology, 2006, Jan-02, Volume: 82, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA; DNA Damage; DNA-Formamidopyrimidine Glycosylase; DNA, Single-Stranded; Electron Transport; Escherichia coli Proteins; Guanine; Light; Membrane Lipids; Metalloporphyrins; Oxidation-Reduction; Phospholipids; Photosensitizing Agents; Piperidines; Proteins; Singlet Oxygen

2006
The mechanism of guanine specific photooxidation in the presence of berberine and palmatine: activation of photosensitized singlet oxygen generation through DNA-binding interaction.
    Chemical research in toxicology, 2005, Volume: 18, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA Damage; Guanine; Humans; Models, Chemical; Oxidation-Reduction; Photosensitizing Agents; Singlet Oxygen; Spectrometry, Fluorescence

2005
Guanine-specific DNA oxidation photosensitized by the tetraphenylporphyrin phosphorus(V) complex via singlet oxygen generation and electron transfer.
    Journal of photochemistry and photobiology. B, Biology, 2007, Jun-26, Volume: 87, Issue:3

    Topics: DNA; DNA Damage; Electrons; Guanine; Oxidation-Reduction; Phosphorus; Photosensitivity Disorders; Porphyrins; Singlet Oxygen

2007
DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts.
    Journal of the American Chemical Society, 2008, Jan-16, Volume: 130, Issue:2

    Topics: Deoxyguanosine; DNA; DNA Adducts; Guanine; Guanosine; Lysine; Oxidation-Reduction; Proteins; Singlet Oxygen

2008
Probing nucleic acid structure with shape-selective rhodium and ruthenium complexes.
    Current protocols in nucleic acid chemistry, 2001, Volume: Chapter 6

    Topics: Base Pair Mismatch; Biochemistry; DNA; DNA Footprinting; Guanine; Nucleic Acid Conformation; Nucleic Acids; Phenanthrolines; Photolysis; Rhodium; RNA; Ruthenium; Ruthenium Compounds; Singlet Oxygen; Stereoisomerism

2001
Oxidatively generated damage to DNA by UVA radiation in cells and human skin.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:5

    Topics: Cells, Cultured; DNA Breaks, Double-Stranded; DNA Damage; Guanine; Humans; Hydroxyl Radical; Oxidative Stress; Singlet Oxygen; Skin; Ultraviolet Rays

2011
Comparative analysis of four oxidized guanine lesions from reactions of DNA with peroxynitrite, singlet oxygen, and γ-radiation.
    Chemical research in toxicology, 2013, Feb-18, Volume: 26, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Deoxyguanosine; DNA; Gamma Rays; Guanidines; Guanine; Guanosine; Hydantoins; Oxidants; Oxidation-Reduction; Peroxynitrous Acid; Rose Bengal; Singlet Oxygen; Spiro Compounds

2013
Formation of guanine-6-sulfonate from 6-thioguanine and singlet oxygen: a combined theoretical and experimental study.
    Journal of the American Chemical Society, 2013, Mar-20, Volume: 135, Issue:11

    Topics: Arylsulfonates; Guanine; Kinetics; Models, Molecular; Oxidation-Reduction; Quantum Theory; Singlet Oxygen; Thermodynamics; Thioguanine

2013
De novo generation of singlet oxygen and ammine ligands by photoactivation of a platinum anticancer complex.
    Angewandte Chemie (International ed. in English), 2013, Dec-16, Volume: 52, Issue:51

    Topics: Antineoplastic Agents; Guanine; Ligands; Oxidation-Reduction; Platinum; Singlet Oxygen

2013
Total inhibition of (1)O2-induced oxidative damage to guanine bases of DNA/RNA by turmeric extracts.
    Biochemical and biophysical research communications, 2014, Sep-26, Volume: 452, Issue:3

    Topics: Antioxidants; Curcuma; DNA Damage; Ethanol; Guanine; Hydrogen Peroxide; Light; Methanol; Models, Chemical; Molybdenum; Photosensitizing Agents; Plant Extracts; Riboflavin; Singlet Oxygen; Solutions; Solvents; Water

2014
Stability of the guanine endoperoxide intermediate: a computational challenge for density functional theory.
    The journal of physical chemistry. A, 2014, Dec-11, Volume: 118, Issue:49

    Topics: Guanine; Molecular Structure; Peroxides; Quantum Theory; Singlet Oxygen

2014
Nanopore detection of 8-oxoguanine in the human telomere repeat sequence.
    ACS nano, 2015, Volume: 9, Issue:4

    Topics: Crown Ethers; G-Quadruplexes; Guanine; Hemolysin Proteins; Humans; Kinetics; Nanomedicine; Nanopores; Nanotechnology; Repetitive Sequences, Nucleic Acid; Singlet Oxygen; Telomere

2015
Indirect photochemical transformations of acyclovir and penciclovir in aquatic environments increase ecological risk.
    Environmental toxicology and chemistry, 2016, Volume: 35, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Daphnia; Guanine; Kinetics; Microalgae; Oxidation-Reduction; Photobacterium; Risk Assessment; Singlet Oxygen; Sunlight; Tandem Mass Spectrometry

2016
Laser controlled singlet oxygen generation in mitochondria to promote mitochondrial DNA replication in vitro.
    Scientific reports, 2015, Nov-18, Volume: 5

    Topics: Cell Proliferation; DNA Polymerase gamma; DNA Replication; DNA-Binding Proteins; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Gene Dosage; Guanine; HeLa Cells; Humans; Lasers; Mitochondria; Mitochondrial Proteins; Oxidative Stress; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Reactive Oxygen Species; Singlet Oxygen; Transcription Factors

2015
Capturing Transient Endoperoxide in the Singlet Oxygen Oxidation of Guanine.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Feb-24, Volume: 22, Issue:9

    Topics: Cycloaddition Reaction; DNA; Guanine; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Oxidation-Reduction; Singlet Oxygen; Water

2016
How protonation and deprotonation of 9-methylguanine alter its singlet O2 addition path: about the initial stage of guanine nucleoside oxidation.
    Physical chemistry chemical physics : PCCP, 2016, 06-01, Volume: 18, Issue:22

    Topics: DNA; Guanine; Kinetics; Models, Molecular; Oxidation-Reduction; Peroxides; Protons; Singlet Oxygen; Water

2016
Singlet Oxygen Attack on Guanine: Reactivity and Structural Signature within the B-DNA Helix.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2016, Aug-22, Volume: 22, Issue:35

    Topics: Base Pairing; DNA, B-Form; Guanine; Molecular Dynamics Simulation; Oxidation-Reduction; Polydeoxyribonucleotides; Singlet Oxygen

2016
Computational Study of Oxidation of Guanine by Singlet Oxygen (
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Apr-27, Volume: 23, Issue:24

    Topics: Cycloaddition Reaction; Cyclohexenes; Guanine; Lysine; Methylamines; Oxidation-Reduction; Photosensitizing Agents; Singlet Oxygen; Thermodynamics; Water

2017
pH-Dependent Singlet O
    The journal of physical chemistry. B, 2018, 01-11, Volume: 122, Issue:1

    Topics: Chlorine; Guanidines; Guanine; Guanosine; Hydantoins; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Conformation; Oxidation-Reduction; Singlet Oxygen; Spectrometry, Mass, Electrospray Ionization; Spiro Compounds; Tandem Mass Spectrometry

2018
Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis.
    Molecular cell, 2019, 07-11, Volume: 75, Issue:1

    Topics: Cell Division; Cell Line, Tumor; Cell Survival; Chromosome Aberrations; DNA Damage; DNA Glycosylases; DNA Repair; DNA Replication; Gene Expression; Genomic Instability; Guanine; HeLa Cells; Humans; Light; Micronuclei, Chromosome-Defective; Optogenetics; Osteoblasts; Oxidative Stress; Singlet Oxygen; Telomere; Telomere Homeostasis

2019
Identification of the Major Product of Guanine Oxidation in DNA by Ozone.
    Chemical research in toxicology, 2022, 10-17, Volume: 35, Issue:10

    Topics: DNA; Guanine; Guanosine; Nucleosides; Oligodeoxyribonucleotides; Oxidation-Reduction; Ozone; Singlet Oxygen; Solvents

2022