Page last updated: 2024-08-24

sinefungin and s-adenosylmethionine

sinefungin has been researched along with s-adenosylmethionine in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (5.56)	18.7374
1990's	23 (42.59)	18.2507
2000's	16 (29.63)	29.6817
2010's	11 (20.37)	24.3611
2020's	1 (1.85)	2.80

Authors

Authors	Studies
Barton, DH; Géro, SD; Lawrence, F; Quiclet-Sire, B; Robert-Gero, M; Samadi, M	1
Dowden, J; Hong, W; Parry, RV; Pike, RA; Ward, SG	1
Kiss, A; Szilák, L; Venetianer, P	1
Szumlanski, CL; Van Loon, JA; Weinshilboum, RM	1
Borot, C; Lawrence, F; Moulay, L; Phelouzat, MA; Robert-Gero, M; Schaeverbeke, J; Schaeverbeke, M	1
Fujioka, M; Konishi, K	1
Cañada, FJ; Pérez-Sala, D; Rando, RR; Tan, EW	1
Bergerat, A; Guschlbauer, W	1
Aswad, DW; Najbauer, J	1
Friedman, S; Som, S	1
Germain, BJ; O'Connor, CM	1
Lawrence, F; Nolan, LL; Paolantonacci, P; Robert-Géro, M	1
McCammon, MT; Parks, LW	1
Kikuchi, S; Nishitani, H; Okumura, K; Taguchi, H	1
Finta, C; Kiss, A; Sulima, U; Venetianer, P	1
Bacchi, CJ; Garofalo-Hannan, J; Goldberg, B; Lyte, P; Rattendi, D; Yarlett, N	1
Connolly, BA; Szczelkun, MD	1
Basselin, M; Lawrence, F; Phelouzat, MA; Robert-Gero, M	1
Blackburn, GM; Mekhalfia, A; Parsons, ID; Persson, B; Stockley, PG	1
Artymiuk, PJ; Baldwin, GS; Connolly, BA; Hornby, DP; Kelly, SM; Price, NC; Wilson, GW	1
Bleimling, N; Kozak, M; Saenger, W; Schluckebier, G; Weinhold, E	1
Béliveau, R; Boivin, D; Lin, W	1
Janulaitis, A; Maneliene, Z; Petrusyte, M; Vitkute, J	1
Derbécourt, T; Lawrence, F; Robert-Gero, M	1
Jones, PA; Shen, JC; Zingg, JM	1
Podhajska, AJ; Tucholski, J; Zmijewski, JW	1
Abad-Zapatero, C; Kavanaugh, TJ; Schluckebier, G; Stewart, KD; Zhong, P	1
Gumport, RI; Reich, NO; Szegedi, SS	1
Janulaitis, A; Jurenaite-Urbanaviciene, S; Kazlauskiene, R; Lubys, A; Maneliene, Z; Petrusyte, M; Urbelyte, V	1
Ashida, A; Inagaki, K; Kataoka, A; Shu, LY; Tamura, T; Tanaka, H	1
Iwata-Reuyl, D; Van Lanen, SG	1
Bedford, MT; Cheng, D; Lee, J	1
Hodsdon, ME; Keeler, C; Scheuermann, TH	1
Erola, A; Jansson, A; Koskiniemi, H; Mäntsälä, P; Niemi, J; Schneider, G; Wang, J	1
Fabrega, C; Hausmann, S; Lima, CD; Schneller, SW; Shuman, S; Zheng, S	1
Gabruzsk, J; Holmes, WM; Watts, JM	1
Raghavendra, NK; Rao, DN	1
Balaña-Fouce, R; Ordóñez, D; Pérez-Pertejo, Y; Reguera, RM	1
Schwer, B; Shuman, S; Zheng, S	1
Bollati, M; Bolognesi, M; Canard, B; Coutard, B; de Lamballerie, X; Decroly, E; Mastrangelo, E; Milani, M; Nonnis, S; Ricagno, S; Selisko, B; Tedeschi, G	1
Krüger, DH; Matsumura, H; Möncke-Buchner, E; Reich, S; Reuter, M; Rothenberg, M; Terauchi, R; Wagenführ, K	1
Cui, Q; Cygler, M; Lamb, SS; Matte, A; Proteau, A; Shi, R; Sulea, T; Wright, GD; Zakeri, B	1
Bardou, F; Boissier, F; Constant, P; Daffé, M; Julien, S; Mourey, L; Ploux, O; Quémard, A; Vaubourgeix, J	1
Batey, RT; Ceres, P; Garst, AD; Mondragón, E; Montange, RK; van Tyne, D	1
Chao, AT; Chung, KY; Dong, H; Lescar, J; Lim, SP; Shi, PY	1
Ahmed Ouameur, A; Dridi, L; Ouellette, M	1
Bouvet, M; Bricogne, G; Canard, B; Coutard, B; Debarnot, C; Decroly, E; Ferron, F; Gluais, L; Imbert, I; Lescar, J; Ortiz-Lombardia, M; Papageorgiou, N; Sharff, A	1
Clarkson, AB; Merali, S; Moncada, C; Perez-Leal, O	1
Cronan, JE; Lin, S	1
Chae, SW; Park, SW; Song, JJ; Yadav, MK	1
Goto-Ito, S; Hou, YM; Ito, T; Masuda, I; Sekine, S; Suh, SW; Yokoyama, S; Yoshida, K	1
Beane, TJ; Koh, CS; Korostelev, AA; Madireddy, R; Zamore, PD	1
Dumbrepatil, AB; Ghosh, S; Hoff, JD; Kennedy, RT; Malec, PA; Marsh, ENG; Zegalia, KA	1
Brunzelle, J; Inniss, NL; Kiryukhina, O; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L	1

Other Studies

54 other study(ies) available for sinefungin and s-adenosylmethionine

Article	Year
Total synthesis of uracil analogues of sinefungin. Journal of medicinal chemistry, 1992, Volume: 35, Issue:1 Topics: Adenosine; Animals; Antiprotozoal Agents; Kinetics; Leishmania donovani; Structure-Activity Relationship; Uracil	1992
Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases. Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7 Topics: Histone-Lysine N-Methyltransferase; Humans; Inhibitory Concentration 50; Methylation; Protein-Arginine N-Methyltransferases; Repressor Proteins; S-Adenosylmethionine; Substrate Specificity	2010
Purification and biochemical characterization of the EcaI DNA methyltransferase. European journal of biochemistry, 1992, Oct-01, Volume: 209, Issue:1 Topics: Adenosine; Base Sequence; Binding, Competitive; Catalysis; Chemical Phenomena; Chemistry, Physical; DNA; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Methylation; Molecular Sequence Data; Plasmids; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Temperature	1992
Human kidney thiopurine methyltransferase. Photoaffinity labeling with S-adenosyl-L-methionine. Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4 Topics: Adenosine; Affinity Labels; Autoradiography; Chromatography, Ion Exchange; Gallic Acid; Humans; Isoenzymes; Kidney; Mercaptopurine; Methyltransferases; Photolysis; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine	1992
Leishmania donovani: antagonistic effect of S-adenosyl methionine on ultrastructural changes and growth inhibition induced by sinefungin. Experimental parasitology, 1992, Volume: 74, Issue:2 Topics: Adenosine; Animals; Antiprotozoal Agents; Flagella; Golgi Apparatus; Hydrogen-Ion Concentration; Leishmania donovani; Methylation; Microscopy, Electron; Protein O-Methyltransferase; Protozoan Proteins; S-Adenosylmethionine	1992
Reversible inactivation of recombinant rat liver guanidinoacetate methyltransferase by glutathione disulfide. Archives of biochemistry and biophysics, 1991, Aug-15, Volume: 289, Issue:1 Topics: Adenosine; Animals; Cysteine; Enzyme Activation; Enzyme Reactivators; Ethylmaleimide; Glutathione; Glutathione Disulfide; Glycine; Guanidinoacetate N-Methyltransferase; Iodoacetates; Iodoacetic Acid; Kinetics; Liver; Mercaptoethanol; Methyltransferases; Oxidation-Reduction; Rats; Recombinant Proteins; S-Adenosylmethionine; Spectrum Analysis; Sulfhydryl Compounds	1991
Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments. Proceedings of the National Academy of Sciences of the United States of America, 1991, Apr-15, Volume: 88, Issue:8 Topics: Acetylcysteine; Adenosine; Animals; Cattle; Cysteine; GTP-Binding Proteins; In Vitro Techniques; Methylation; Molecular Weight; Rod Cell Outer Segment; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Transducin	1991
The double role of methyl donor and allosteric effector of S-adenosyl-methionine for Dam methylase of E. coli. Nucleic acids research, 1990, Aug-11, Volume: 18, Issue:15 Topics: Adenosine; Allosteric Regulation; Base Sequence; Binding Sites; Binding, Competitive; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Sodium Chloride; Temperature; Thermodynamics	1990
Diversity of methyl acceptor proteins in rat pheochromocytoma (PC12) cells revealed after treatment with adenosine dialdehyde. The Journal of biological chemistry, 1990, Jul-25, Volume: 265, Issue:21 Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Deoxyadenosines; Electrophoresis, Gel, Two-Dimensional; Methylation; Molecular Weight; Neoplasm Proteins; Nerve Tissue Proteins; Pheochromocytoma; Rats; S-Adenosylmethionine; Thionucleosides; Tubercidin; Tumor Cells, Cultured	1990
Direct photolabeling of the EcoRII methyltransferase with S-adenosyl-L-methionine. The Journal of biological chemistry, 1990, Mar-15, Volume: 265, Issue:8 Topics: Adenosine; Affinity Labels; Azides; Base Sequence; Chemical Precipitation; Dithiothreitol; DNA-Cytosine Methylases; DNA, Bacterial; Escherichia coli; Kinetics; Mercaptoethanol; Methylation; Photochemistry; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Trichloroacetic Acid; Ultraviolet Rays	1990
Kinetic and electrophoretic analysis of transmethylation reactions in intact Xenopus laevis oocytes. The Journal of biological chemistry, 1987, Jul-25, Volume: 262, Issue:21 Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Kinetics; Methionine; Methylation; Molecular Weight; Oocytes; S-Adenosylmethionine; Xenopus laevis	1987
Inhibition of leishmanial DNA synthesis by sinefungin. Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17 Topics: Adenosine; Animals; Cell Line; DNA Replication; Leishmania; Macrophages; Mice; Phosphorylation; Protein Biosynthesis; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Thymidine; Transcription, Genetic	1987
Inhibition of sterol transmethylation by S-adenosylhomocysteine analogs. Journal of bacteriology, 1981, Volume: 145, Issue:1 Topics: Adenosine; Ergosterol; Methylation; Methyltransferases; S-Adenosylmethionine; Saccharomyces cerevisiae; Sterols; Structure-Activity Relationship	1981
Finding of a homarine-synthesizing enzyme in turban shell and some properties of the enzyme. Archives of biochemistry and biophysics, 1995, Oct-01, Volume: 322, Issue:2 Topics: Adenosine; Alkaloids; Animals; Cations, Divalent; Enzyme Inhibitors; Glycine; Invertebrates; Methyltransferases; Picolinic Acids; S-Adenosylhomocysteine; S-Adenosylmethionine; Snails; Species Specificity	1995
Purification of the KpnI DNA methyltransferase and photolabeling of the enzyme with S-adenosyl-L-methionine. Gene, 1995, Oct-16, Volume: 164, Issue:1 Topics: Adenosine; Cloning, Molecular; Escherichia coli; Molecular Sequence Data; Protein Binding; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Ultraviolet Rays	1995
Fate of soluble methionine in African trypanosomes: effects of metabolic inhibitors. The Biochemical journal, 1995, Aug-01, Volume: 309 ( Pt 3) Topics: Adenosine; Animals; Half-Life; Methionine; S-Adenosylmethionine; Trypanocidal Agents; Trypanosoma brucei brucei	1995
Sequence-specific binding of DNA by the EcoRV restriction and modification enzymes with nucleic acid and cofactor analogues. Biochemistry, 1995, Aug-29, Volume: 34, Issue:34 Topics: Adenosine; Base Sequence; Binding Sites; Chromatography, High Pressure Liquid; DNA; Escherichia coli; Magnesium; Methylation; Molecular Sequence Data; Oligodeoxyribonucleotides; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific)	1995
Sinefungin shares AdoMet-uptake system to enter Leishmania donovani promastigotes. The Biochemical journal, 1995, Jan-01, Volume: 305 ( Pt 1) Topics: Adenosine; Animals; Drug Resistance; Kinetics; Leishmania donovani; Membrane Transport Proteins; Protozoan Proteins; S-Adenosylmethionine	1995
Probing the molecular mechanism of action of co-repressor in the E. coli methionine repressor-operator complex using surface plasmon resonance (SPR). Nucleic acids research, 1995, Jan-25, Volume: 23, Issue:2 Topics: Adenosine; Bacterial Proteins; Binding Sites; DNA, Bacterial; Electrochemistry; Escherichia coli; Escherichia coli Proteins; Hydrogen-Ion Concentration; Kinetics; Operon; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Repressor Proteins; S-Adenosylmethionine	1995
Ligand-induced conformational states of the cytosine-specific DNA methyltransferase M.HgaI-2. Journal of molecular biology, 1994, Jan-14, Volume: 235, Issue:2 Topics: Adenosine; Amino Acid Sequence; Base Sequence; Circular Dichroism; DNA; DNA-Cytosine Methylases; Ligands; Molecular Sequence Data; Protein Structure, Secondary; S-Adenosylmethionine	1994
Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI. Journal of molecular biology, 1997, Jan-10, Volume: 265, Issue:1 Topics: Adenosine; Binding Sites; Catalysis; Crystallography, X-Ray; Electrochemistry; Enzyme Inhibitors; Escherichia coli; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Spectrometry, Fluorescence	1997
Essential arginine residues in isoprenylcysteine protein carboxyl methyltransferase. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997, Volume: 75, Issue:1 Topics: Adenosine; Animals; Arginine; Cell Membrane; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kidney; Male; Methylation; Phenylglyoxal; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship	1997
BplI, a new BcgI-like restriction endonuclease, which recognizes a symmetric sequence. Nucleic acids research, 1997, Nov-15, Volume: 25, Issue:22 Topics: Adenosine; Bacillus; Bacteriophage lambda; Binding Sites; Deoxyribonucleases, Type II Site-Specific; DNA, Viral; Magnesium; Plasmids; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity	1997
Proton-ATPase activities involved in the uptake of an S-adenosylmethionine analogue. Molecular and biochemical parasitology, 1998, Apr-01, Volume: 92, Issue:1 Topics: Adenosine; Adenosine Triphosphatases; Animals; Biological Transport, Active; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ionophores; Kinetics; Leishmania donovani; Proton-Motive Force; Proton-Translocating ATPases; S-Adenosylmethionine; Sodium	1998
Enzyme-mediated cytosine deamination by the bacterial methyltransferase M.MspI. The Biochemical journal, 1998, May-15, Volume: 332 ( Pt 1) Topics: Adenosine; Bacterial Proteins; Cytosine; Deamination; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Molecular Structure; Moraxella; Mutation; Neomycin; S-Adenosylhomocysteine; S-Adenosylmethionine	1998
Two intertwined methylation activities of the MmeI restriction-modification class-IIS system from Methylophilus methylotrophus. Gene, 1998, Nov-26, Volume: 223, Issue:1-2 Topics: Adenosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; DNA, Bacterial; Gram-Negative Aerobic Bacteria; Methylation; Methyltransferases; S-Adenosylmethionine	1998
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism. Journal of molecular biology, 1999, Jun-04, Volume: 289, Issue:2 Topics: Adenosine; Amino Acid Sequence; Antifungal Agents; Bacillus subtilis; Binding Sites; Crystallography, X-Ray; Drug Resistance, Microbial; Ligands; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; RNA, Ribosomal, 23S; S-Adenosylhomocysteine; S-Adenosylmethionine	1999
Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferase. Nucleic acids research, 2000, Oct-15, Volume: 28, Issue:20 Topics: Adenine; Adenosine; Binding Sites; Buffers; Carbon Radioisotopes; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; DNA; DNA Methylation; DNA-Binding Proteins; Fluorescence; Kinetics; Nucleic Acid Conformation; Protein Binding; Rhodobacter sphaeroides; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Thermodynamics	2000
Characterization of BseMII, a new type IV restriction-modification system, which recognizes the pentanucleotide sequence 5'-CTCAG(N)(10/8)/. Nucleic acids research, 2001, Feb-15, Volume: 29, Issue:4 Topics: Adenosine; Base Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; DNA Restriction Enzymes; Geobacillus stearothermophilus; Magnesium; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Protein Subunits; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity	2001
An in vitro screening method for DNA cytosine-C5-methylase inhibitor. Natural product letters, 2002, Volume: 16, Issue:1 Topics: Adenosine; Bacteria; Deoxyribonucleases, Type II Site-Specific; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction-Modification Enzymes; DNA-Cytosine Methylases; Electrophoresis, Agar Gel; Enzyme Inhibitors; Escherichia coli; In Vitro Techniques; S-Adenosylmethionine; Sequence Homology, Nucleic Acid; X Chromosome	2002
Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA). Biochemistry, 2003, May-13, Volume: 42, Issue:18 Topics: Adenosine; Binding, Competitive; Catalysis; Escherichia coli; Isomerases; Kinetics; Magnetic Resonance Spectroscopy; Nucleoside Q; Pentosyltransferases; Ribose; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine	2003
Techniques in protein methylation. Methods in molecular biology (Clifton, N.J.), 2004, Volume: 284 Topics: Adaptor Proteins, Signal Transducing; Adenosine; DNA-Binding Proteins; Enzyme Inhibitors; Glutathione Transferase; HeLa Cells; Histones; Humans; Intracellular Signaling Peptides and Proteins; Methylation; Methyltransferases; Poly(A)-Binding Protein I; Precipitin Tests; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; RNA-Binding Proteins; S-Adenosylmethionine; Signal Transduction; Substrate Specificity	2004
Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone. Biochemistry, 2004, Sep-28, Volume: 43, Issue:38 Topics: Adenosine; Animals; Conserved Sequence; Mammals; Methyltransferases; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Secondary; Pseudomonas syringae; S-Adenosylmethionine	2004
Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor. The Journal of biological chemistry, 2005, Feb-04, Volume: 280, Issue:5 Topics: Adenosine; Anthracyclines; Antimalarials; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coenzymes; Hydroxylation; Mass Spectrometry; Mixed Function Oxygenases; Mutagenesis; Oxygen; Protein Structure, Tertiary; S-Adenosylmethionine; Streptomyces; Substrate Specificity	2005
Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis. The Journal of biological chemistry, 2005, May-27, Volume: 280, Issue:21 Topics: Adenosine; Animals; Binding Sites; Crystallization; Encephalitozoon cuniculi; Enzyme Inhibitors; Guanosine Triphosphate; Hydrogen-Ion Concentration; Methylation; Methyltransferases; Models, Molecular; Molecular Structure; Mutagenesis; Mutation, Missense; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity	2005
Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase. Biochemistry, 2005, May-03, Volume: 44, Issue:17 Topics: Adenosine; Amino Acid Sequence; Anticodon; Base Sequence; Escherichia coli Proteins; Fluorescence Resonance Energy Transfer; Ligands; Methylation; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Protein Conformation; Protein Footprinting; RNA-Binding Proteins; RNA, Transfer, Leu; S-Adenosylmethionine; Sequence Alignment; Thermotoga maritima; tRNA Methyltransferases	2005
Exogenous AdoMet and its analogue sinefungin differentially influence DNA cleavage by R.EcoP15I--usefulness in SAGE. Biochemical and biophysical research communications, 2005, Sep-02, Volume: 334, Issue:3 Topics: Adenosine; Deoxyribonucleases, Type III Site-Specific; DNA; DNA, Circular; DNA, Superhelical; Gene Expression Profiling; Repressor Proteins; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific)	2005
Characterization of a methionine adenosyltransferase over-expressing strain in the trypanosomatid Leishmania donovani. Biochimica et biophysica acta, 2006, Volume: 1760, Issue:1 Topics: Adenosine; Animals; Cloning, Molecular; Drug Resistance; Leishmania donovani; Methionine Adenosyltransferase; Neomycin; Polyamines; S-Adenosylmethionine; Trypanosomatina	2006
Sinefungin resistance of Saccharomyces cerevisiae arising from Sam3 mutations that inactivate the AdoMet transporter or from increased expression of AdoMet synthase plus mRNA cap guanine-N7 methyltransferase. Nucleic acids research, 2007, Volume: 35, Issue:20 Topics: Adenosine; Amino Acid Transport Systems; Antifungal Agents; Drug Resistance, Fungal; Methionine Adenosyltransferase; Methyltransferases; Mutation; S-Adenosylmethionine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2007
Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus. Journal of molecular biology, 2009, Jan-09, Volume: 385, Issue:1 Topics: Adenosine; Amino Acid Sequence; Binding Sites; Biological Assay; Crystallography, X-Ray; Flavivirus; Guanosine Triphosphate; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; RNA Caps; S-Adenosylmethionine; Sequence Alignment; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Viral Nonstructural Proteins	2009
Functional characterization and modulation of the DNA cleavage efficiency of type III restriction endonuclease EcoP15I in its interaction with two sites in the DNA target. Journal of molecular biology, 2009, Apr-17, Volume: 387, Issue:5 Topics: Adenosine; Base Sequence; Binding Sites; Deoxyribonucleases, Type III Site-Specific; DNA Methylation; DNA, Bacterial; Escherichia coli; Gene Expression Profiling; S-Adenosylmethionine; Substrate Specificity	2009
Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. Chemistry & biology, 2009, Apr-24, Volume: 16, Issue:4 Topics: Actinomycetales; Adenosine; Anti-Bacterial Agents; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Methyltransferases; Models, Molecular; Point Mutation; Protein Binding; Protein Multimerization; S-Adenosylhomocysteine; S-Adenosylmethionine; Teicoplanin	2009
S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases. The Journal of biological chemistry, 2009, Jul-17, Volume: 284, Issue:29 Topics: Adenosine; Catalytic Domain; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Methyltransferases; Models, Molecular; Molecular Structure; Mycobacterium; Mycobacterium tuberculosis; Mycolic Acids; Protein Binding; Protein Structure, Tertiary; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity	2009
Discrimination between closely related cellular metabolites by the SAM-I riboswitch. Journal of molecular biology, 2010, Feb-26, Volume: 396, Issue:3 Topics: Adenosine; Base Pairing; Conserved Sequence; Crystallography, X-Ray; Kinetics; Models, Molecular; Mutation; Nucleic Acid Conformation; RNA, Bacterial; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine	2010
Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus. Virology, 2010, Jun-20, Volume: 402, Issue:1 Topics: Adenosine; Animals; Dengue Virus; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Methylation; Methyltransferases; RNA; S-Adenosylmethionine; Viral Proteins	2010
High affinity S-Adenosylmethionine plasma membrane transporter of Leishmania is a member of the folate biopterin transporter (FBT) family. The Journal of biological chemistry, 2010, Jun-25, Volume: 285, Issue:26 Topics: Adenosine; Antiprotozoal Agents; Biological Transport; Biopterins; Blotting, Western; Cell Membrane; Drug Resistance, Bacterial; Folic Acid; Folic Acid Antagonists; Green Fluorescent Proteins; Leishmania; Membrane Transport Proteins; Methotrexate; Microscopy, Fluorescence; Mutation; Protozoan Proteins; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; S-Adenosylmethionine	2010
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex. PLoS pathogens, 2011, Volume: 7, Issue:5 Topics: Adenosine; Crystallization; Magnesium; Methyltransferases; Mutation; Plasmids; Protein Binding; RNA Caps; RNA, Viral; S-Adenosylmethionine; Severe acute respiratory syndrome-related coronavirus; Viral Nonstructural Proteins	2011
Pneumocystis S-adenosylmethionine transport: a potential drug target. American journal of respiratory cell and molecular biology, 2011, Volume: 45, Issue:6 Topics: Adenosine; Animals; Antifungal Agents; Biological Transport; Drug Delivery Systems; Fungal Proteins; Humans; Methionine Adenosyltransferase; Pneumocystis carinii; Pneumonia, Pneumocystis; Recombinant Proteins; S-Adenosylmethionine; Saccharomyces cerevisiae	2011
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis. The Journal of biological chemistry, 2012, Oct-26, Volume: 287, Issue:44 Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Bacillus cereus; Bacterial Proteins; Biotin; Carrier Proteins; Chromatography, Gel; Conserved Sequence; Escherichia coli; Fatty Acids; Genetic Complementation Test; Hydrogen-Ion Concentration; Methionine; Molecular Sequence Data; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity	2012
Sinefungin, a natural nucleoside analogue of S-adenosylmethionine, inhibits Streptococcus pneumoniae biofilm growth. BioMed research international, 2014, Volume: 2014 Topics: Adenosine; Animals; Biofilms; Colony Count, Microbial; Gene Expression Regulation, Bacterial; Homocysteine; Otitis Media; Plankton; Rats, Sprague-Dawley; S-Adenosylmethionine; Streptococcus pneumoniae	2014
Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD. Proceedings of the National Academy of Sciences of the United States of America, 2015, Aug-04, Volume: 112, Issue:31 Topics: Adenosine; Amino Acid Sequence; Anticodon; Base Sequence; Binding Sites; Biocatalysis; Crystallography, X-Ray; Escherichia coli Proteins; Guanine; Haemophilus influenzae; Kinetics; Methylation; Models, Molecular; Molecular Sequence Data; RNA, Transfer; S-Adenosylmethionine; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Thermotoga maritima; tRNA Methyltransferases	2015
Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine. Scientific reports, 2017, 04-20, Volume: 7, Issue:1 Topics: Adenosine; Binding Sites; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; Models, Molecular; Mutation; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Pseudouridine; RNA, Ribosomal, 23S; S-Adenosylmethionine; Substrate Specificity	2017
Viperin interacts with the kinase IRAK1 and the E3 ubiquitin ligase TRAF6, coupling innate immune signaling to antiviral ribonucleotide synthesis. The Journal of biological chemistry, 2019, 04-26, Volume: 294, Issue:17 Topics: Adenosine; Antiviral Agents; Cytidine Triphosphate; Half-Life; HEK293 Cells; Humans; Immunity, Innate; Interleukin-1 Receptor-Associated Kinases; Intracellular Signaling Peptides and Proteins; Oxidoreductases Acting on CH-CH Group Donors; Phosphorylation; Protein Binding; Proteins; S-Adenosylmethionine; Signal Transduction; TNF Receptor-Associated Factor 6; Ubiquitination	2019
High-resolution structures of the SARS-CoV-2 2'- Science signaling, 2020, 09-29, Volume: 13, Issue:651 Topics: Adenosine; Betacoronavirus; Binding Sites; Catalytic Domain; Coronavirus Infections; COVID-19; Crystallography, X-Ray; Dimerization; Genes, Viral; Humans; Methylation; Methyltransferases; Models, Molecular; Open Reading Frames; Pandemics; Pneumonia, Viral; Protein Binding; Protein Conformation; RNA Cap Analogs; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; SARS-CoV-2; Structure-Activity Relationship; Viral Nonstructural Proteins	2020