Page last updated: 2024-08-24

sinefungin and s-adenosylhomocysteine

sinefungin has been researched along with s-adenosylhomocysteine in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (12.20)	18.7374
1990's	14 (34.15)	18.2507
2000's	11 (26.83)	29.6817
2010's	8 (19.51)	24.3611
2020's	3 (7.32)	2.80

Authors

Authors	Studies
Bleimling, N; Kozak, M; Saenger, W; Schluckebier, G; Weinhold, E	1
Abad-Zapatero, C; Kavanaugh, TJ; Schluckebier, G; Stewart, KD; Zhong, P	1
Blackburn, GM; Couture, JF; Hauk, G; Thompson, MJ; Trievel, RC	1
Behnam, MA; Boldescu, V; Klein, CD; Nitsche, C	1
Cheng, ZQ; Jiang, CS; Song, JL; Tao, HR; Zhang, H; Zhu, K	1
Babault, N; Craveur, P; Emanuelli, M; Gao, Y; Jin, J; Martin, NI; Moret, EE; Rood, JJM; Salvucci, A; Sartini, D; van Haren, MJ	1
Ahmed-Belkacem, R; Canard, B; Debart, F; Decroly, E; Guiraud, M; Sutto-Ortiz, P; Vasseur, JJ	1
Fischer, TR; Helm, M; Hoba, SN; Jung, N; Kersten, C; Koch, J; Lyko, F; Meidner, JL; Schirmeister, T; Schwickert, M; Stark, MM; Weber, M; Windbergs, M; Zimmermann, RA	1
Kiss, A; Szilák, L; Venetianer, P	1
Szumlanski, CL; Van Loon, JA; Weinshilboum, RM	1
Cañada, FJ; Pérez-Sala, D; Rando, RR; Tan, EW	1
Bergerat, A; Guschlbauer, W	1
Barbés, C; Hardisson, C; Robert-Geró, M; Sánchez, J; Yebra, MJ	1
Friedman, S; Som, S	1
Barten, DM; Hogenkamp, HP; Mirkin, BL; O'Dea, RF	1
Lawrence, F; Nolan, LL; Paolantonacci, P; Robert-Géro, M	1
Robert-Géro, M; Vedel, M	1
Borchardt, RT; Pugh, CS	1
Hansen, JA; Mirkin, BL; O'Dea, RF; O'Leary, M	1
Kikuchi, S; Nishitani, H; Okumura, K; Taguchi, H	1
Finta, C; Kiss, A; Sulima, U; Venetianer, P	1
Kowluru, A; Li, G; Metz, SA	1
Béliveau, R; Boivin, D; Lin, W	1
Janulaitis, A; Maneliene, Z; Petrusyte, M; Vitkute, J	1
Jones, PA; Shen, JC; Zingg, JM	1
Gumport, RI; Reich, NO; Szegedi, SS	1
Janulaitis, A; Jurenaite-Urbanaviciene, S; Kazlauskiene, R; Lubys, A; Maneliene, Z; Petrusyte, M; Urbelyte, V	1
Iwata-Reuyl, D; Van Lanen, SG	1
Fabrega, C; Hausmann, S; Lima, CD; Schneller, SW; Shuman, S; Zheng, S	1
Cheng, X; Hattman, S; Horton, JR; Jeltsch, A; Liebert, K	1
Couture, JF; Dietzel, K; Dirk, LM; Flynn, EM; Houtz, RL; Trievel, RC	1
Lescar, J; Lim, SP; Vasudevan, SG; Wen, D; Yan, CK; Yap, TL	1
Benarroch, D; Qiu, ZR; Schwer, B; Shuman, S	1
Cui, Q; Cygler, M; Lamb, SS; Matte, A; Proteau, A; Shi, R; Sulea, T; Wright, GD; Zakeri, B	1
Bardou, F; Boissier, F; Constant, P; Daffé, M; Julien, S; Mourey, L; Ploux, O; Quémard, A; Vaubourgeix, J	1
Batey, RT; Ceres, P; Garst, AD; Mondragón, E; Montange, RK; van Tyne, D	1
Beis, K; Cameron, AD; Choudhury, HG; Iwata, S	1
Atadja, P; Fan, H; Frederiksen, M; Gao, J; Gu, XJ; Guo, W; Harrington, E; Jiang, L; Li, E; Li, S; Lin, Y; Lu, C; Meier, P; Scheufler, C; Wang, Z; Xu, YC; Zhao, K; Zhou, S	1
Cronan, JE; Lin, S	1
Banavali, N; Brecher, M; Chen, H; Ghosh, AK; Jones, SA; Kramer, LD; Li, H; Li, Z; Nag, D; Zhang, J; Zhou, B	1
Brunzelle, J; Inniss, NL; Kiryukhina, O; Minasov, G; Rosas-Lemus, M; Satchell, KJF; Shuvalova, L	1

Reviews

1 review(s) available for sinefungin and s-adenosylhomocysteine

Article	Year
The Medicinal Chemistry of Dengue Virus. Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12 Topics: Antiviral Agents; Chemistry, Pharmaceutical; Dengue; Dengue Virus; Humans; Molecular Conformation; Structure-Activity Relationship	2016

Other Studies

40 other study(ies) available for sinefungin and s-adenosylhomocysteine

Article	Year
Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI. Journal of molecular biology, 1997, Jan-10, Volume: 265, Issue:1 Topics: Adenosine; Binding Sites; Catalysis; Crystallography, X-Ray; Electrochemistry; Enzyme Inhibitors; Escherichia coli; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Spectrometry, Fluorescence	1997
The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism. Journal of molecular biology, 1999, Jun-04, Volume: 289, Issue:2 Topics: Adenosine; Amino Acid Sequence; Antifungal Agents; Bacillus subtilis; Binding Sites; Crystallography, X-Ray; Drug Resistance, Microbial; Ligands; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; RNA, Ribosomal, 23S; S-Adenosylhomocysteine; S-Adenosylmethionine	1999
Catalytic roles for carbon-oxygen hydrogen bonding in SET domain lysine methyltransferases. The Journal of biological chemistry, 2006, Jul-14, Volume: 281, Issue:28 Topics: Arabidopsis; Binding Sites; Carbon; Catalysis; Cloning, Molecular; Histone-Lysine N-Methyltransferase; Hydrogen Bonding; Kinetics; Lysine; Oxygen; Protein Structure, Tertiary	2006
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors. Bioorganic & medicinal chemistry letters, 2018, 12-15, Volume: 28, Issue:23-24 Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Discovery; Enzyme Inhibitors; Humans; Isoquinolines; Leukemia; Lymphoma; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein-Arginine N-Methyltransferases; Structure-Activity Relationship	2018
Bisubstrate Inhibitors of Nicotinamide Journal of medicinal chemistry, 2019, 07-25, Volume: 62, Issue:14 Topics: Antineoplastic Agents; Catalytic Domain; Cell Line, Tumor; Enzyme Inhibitors; Humans; Models, Molecular; Mouth Neoplasms; Naphthalenes; Niacinamide; Nicotinamide N-Methyltransferase	2019
Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase. European journal of medicinal chemistry, 2020, Sep-01, Volume: 201 Topics: Adenine; Betacoronavirus; Coronavirus Infections; COVID-19; Exoribonucleases; Humans; Methylation; Methyltransferases; Molecular Docking Simulation; Nucleosides; Pandemics; Pneumonia, Viral; RNA Caps; RNA, Viral; S-Adenosylmethionine; SARS-CoV-2; Viral Nonstructural Proteins	2020
Discovery of Inhibitors of DNA Methyltransferase 2, an Epitranscriptomic Modulator and Potential Target for Cancer Treatment. Journal of medicinal chemistry, 2022, 07-28, Volume: 65, Issue:14 Topics: Archaeal Proteins; Caco-2 Cells; DNA; Humans; Methyltransferases; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine	2022
Purification and biochemical characterization of the EcaI DNA methyltransferase. European journal of biochemistry, 1992, Oct-01, Volume: 209, Issue:1 Topics: Adenosine; Base Sequence; Binding, Competitive; Catalysis; Chemical Phenomena; Chemistry, Physical; DNA; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Methylation; Molecular Sequence Data; Plasmids; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Temperature	1992
Human kidney thiopurine methyltransferase. Photoaffinity labeling with S-adenosyl-L-methionine. Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4 Topics: Adenosine; Affinity Labels; Autoradiography; Chromatography, Ion Exchange; Gallic Acid; Humans; Isoenzymes; Kidney; Mercaptopurine; Methyltransferases; Photolysis; Polymorphism, Genetic; S-Adenosylhomocysteine; S-Adenosylmethionine	1992
Methylation and demethylation reactions of guanine nucleotide-binding proteins of retinal rod outer segments. Proceedings of the National Academy of Sciences of the United States of America, 1991, Apr-15, Volume: 88, Issue:8 Topics: Acetylcysteine; Adenosine; Animals; Cattle; Cysteine; GTP-Binding Proteins; In Vitro Techniques; Methylation; Molecular Weight; Rod Cell Outer Segment; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction; Transducin	1991
The double role of methyl donor and allosteric effector of S-adenosyl-methionine for Dam methylase of E. coli. Nucleic acids research, 1990, Aug-11, Volume: 18, Issue:15 Topics: Adenosine; Allosteric Regulation; Base Sequence; Binding Sites; Binding, Competitive; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Sodium Chloride; Temperature; Thermodynamics	1990
Effects of sinefungin and S-adenosylhomocysteine on DNA and protein methyltransferases from Streptomyces and other bacteria. FEMS microbiology letters, 1990, Jun-01, Volume: 57, Issue:3 Topics: Adenosine; Chromatography, Thin Layer; DNA Modification Methylases; Protein Methyltransferases; S-Adenosylhomocysteine; Streptomyces	1990
Direct photolabeling of the EcoRII methyltransferase with S-adenosyl-L-methionine. The Journal of biological chemistry, 1990, Mar-15, Volume: 265, Issue:8 Topics: Adenosine; Affinity Labels; Azides; Base Sequence; Chemical Precipitation; Dithiothreitol; DNA-Cytosine Methylases; DNA, Bacterial; Escherichia coli; Kinetics; Mercaptoethanol; Methylation; Photochemistry; Protein Conformation; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity; Trichloroacetic Acid; Ultraviolet Rays	1990
Effect of adenosine analogues on protein carboxylmethyltransferase, S-adenosylhomocysteine hydrolase, and ribonucleotide reductase activity in murine neuroblastoma cells. Cancer research, 1987, Jul-15, Volume: 47, Issue:14 Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Survival; Cells, Cultured; Hydrolases; Mice; Neuroblastoma; Protein Methyltransferases; Protein O-Methyltransferase; Ribonucleotide Reductases; S-Adenosylhomocysteine; Tubercidin	1987
Inhibition of leishmanial DNA synthesis by sinefungin. Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17 Topics: Adenosine; Animals; Cell Line; DNA Replication; Leishmania; Macrophages; Mice; Phosphorylation; Protein Biosynthesis; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity; Thymidine; Transcription, Genetic	1987
Comparative effect of S-adenosyl-homocysteine (SAH) and Sinefungin on tRNA-base methylation in whole cells and in vitro. FEBS letters, 1981, Jun-01, Volume: 128, Issue:1 Topics: Adenine; Adenosine; Animals; Antifungal Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Escherichia coli; Guanine; Homocysteine; Methylation; RNA, Transfer; S-Adenosylhomocysteine	1981
Effects of S-adenosylhomocysteine analogues on vaccinia viral messenger ribonucleic acid synthesis and methylation. Biochemistry, 1982, Mar-30, Volume: 21, Issue:7 Topics: Adenosine; Chemical Phenomena; Chemistry; DNA-Directed RNA Polymerases; Homocysteine; Kinetics; Methyltransferases; Nucleotidyltransferases; RNA, Viral; S-Adenosylhomocysteine; Structure-Activity Relationship; Vaccinia virus	1982
Protein carboxyl-O-methyltransferase activity in cultured C-1300 neuroblastoma cells. Biochemical pharmacology, 1983, Aug-01, Volume: 32, Issue:15 Topics: Adenosine; Animals; Cells, Cultured; Kinetics; Mice; Neuroblastoma; Protein Methyltransferases; Protein O-Methyltransferase; S-Adenosylhomocysteine; Tissue Distribution	1983
Finding of a homarine-synthesizing enzyme in turban shell and some properties of the enzyme. Archives of biochemistry and biophysics, 1995, Oct-01, Volume: 322, Issue:2 Topics: Adenosine; Alkaloids; Animals; Cations, Divalent; Enzyme Inhibitors; Glycine; Invertebrates; Methyltransferases; Picolinic Acids; S-Adenosylhomocysteine; S-Adenosylmethionine; Snails; Species Specificity	1995
Purification of the KpnI DNA methyltransferase and photolabeling of the enzyme with S-adenosyl-L-methionine. Gene, 1995, Oct-16, Volume: 164, Issue:1 Topics: Adenosine; Cloning, Molecular; Escherichia coli; Molecular Sequence Data; Protein Binding; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Ultraviolet Rays	1995
Characterization of prenylcysteine methyltransferase in insulin-secreting cells. The Biochemical journal, 1996, May-15, Volume: 316 ( Pt 1) Topics: Adenosine; Animals; Cell Fractionation; Cell Line; Enzyme Inhibitors; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Organelles; Protein Methyltransferases; Rats; S-Adenosylhomocysteine; Subcellular Fractions	1996
Essential arginine residues in isoprenylcysteine protein carboxyl methyltransferase. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997, Volume: 75, Issue:1 Topics: Adenosine; Animals; Arginine; Cell Membrane; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kidney; Male; Methylation; Phenylglyoxal; Protein Methyltransferases; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship	1997
BplI, a new BcgI-like restriction endonuclease, which recognizes a symmetric sequence. Nucleic acids research, 1997, Nov-15, Volume: 25, Issue:22 Topics: Adenosine; Bacillus; Bacteriophage lambda; Binding Sites; Deoxyribonucleases, Type II Site-Specific; DNA, Viral; Magnesium; Plasmids; S-Adenosylhomocysteine; S-Adenosylmethionine; Substrate Specificity	1997
Enzyme-mediated cytosine deamination by the bacterial methyltransferase M.MspI. The Biochemical journal, 1998, May-15, Volume: 332 ( Pt 1) Topics: Adenosine; Bacterial Proteins; Cytosine; Deamination; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Molecular Structure; Moraxella; Mutation; Neomycin; S-Adenosylhomocysteine; S-Adenosylmethionine	1998
Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferase. Nucleic acids research, 2000, Oct-15, Volume: 28, Issue:20 Topics: Adenine; Adenosine; Binding Sites; Buffers; Carbon Radioisotopes; Catalysis; Chromatography, High Pressure Liquid; Coenzymes; DNA; DNA Methylation; DNA-Binding Proteins; Fluorescence; Kinetics; Nucleic Acid Conformation; Protein Binding; Rhodobacter sphaeroides; S-Adenosylhomocysteine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Thermodynamics	2000
Characterization of BseMII, a new type IV restriction-modification system, which recognizes the pentanucleotide sequence 5'-CTCAG(N)(10/8)/. Nucleic acids research, 2001, Feb-15, Volume: 29, Issue:4 Topics: Adenosine; Base Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; DNA Restriction Enzymes; Geobacillus stearothermophilus; Magnesium; Molecular Sequence Data; Molecular Weight; Multienzyme Complexes; Protein Subunits; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Analysis, DNA; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity	2001
Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA). Biochemistry, 2003, May-13, Volume: 42, Issue:18 Topics: Adenosine; Binding, Competitive; Catalysis; Escherichia coli; Isomerases; Kinetics; Magnetic Resonance Spectroscopy; Nucleoside Q; Pentosyltransferases; Ribose; RNA, Transfer; S-Adenosylhomocysteine; S-Adenosylmethionine	2003
Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis. The Journal of biological chemistry, 2005, May-27, Volume: 280, Issue:21 Topics: Adenosine; Animals; Binding Sites; Crystallization; Encephalitozoon cuniculi; Enzyme Inhibitors; Guanosine Triphosphate; Hydrogen-Ion Concentration; Methylation; Methyltransferases; Models, Molecular; Molecular Structure; Mutagenesis; Mutation, Missense; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Structure-Activity Relationship; Substrate Specificity	2005
Transition from nonspecific to specific DNA interactions along the substrate-recognition pathway of dam methyltransferase. Cell, 2005, May-06, Volume: 121, Issue:3 Topics: Adenine; Adenosine; Amino Acid Sequence; Amino Acid Substitution; Bacteriophage T4; Base Sequence; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; DNA; Escherichia coli; Escherichia coli Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Protein Binding; Protein Conformation; S-Adenosylhomocysteine; Sequence Homology, Amino Acid; Site-Specific DNA-Methyltransferase (Adenine-Specific); Substrate Specificity; Viral Proteins	2005
Kinetic manifestation of processivity during multiple methylations catalyzed by SET domain protein methyltransferases. Biochemistry, 2007, Mar-27, Volume: 46, Issue:12 Topics: Adenosine; Animals; Catalysis; Cattle; Cell Cycle Proteins; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Kinetics; Lysine; Methylation; Methyltransferases; Models, Chemical; Multienzyme Complexes; Pisum sativum; Plant Proteins; Protein Methyltransferases; Protein Structure, Tertiary; S-Adenosylhomocysteine; Schizosaccharomyces pombe Proteins	2007
A scintillation proximity assay for dengue virus NS5 2'-O-methyltransferase-kinetic and inhibition analyses. Antiviral research, 2008, Volume: 80, Issue:3 Topics: Adenosine; Binding Sites; Biochemistry; Dengue Virus; Enzyme Inhibitors; Guanosine Triphosphate; Kinetics; Methylation; Methyltransferases; S-Adenosylhomocysteine; Scintillation Counting; Sensitivity and Specificity; Viral Proteins	2008
Characterization of a mimivirus RNA cap guanine-N2 methyltransferase. RNA (New York, N.Y.), 2009, Volume: 15, Issue:4 Topics: Adenosine; Amino Acid Sequence; Animals; DNA Viruses; Enzyme Inhibitors; Guanosine; Humans; Methyltransferases; Molecular Sequence Data; RNA Caps; RNA, Messenger; S-Adenosylhomocysteine; Sequence Alignment	2009
Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. Chemistry & biology, 2009, Apr-24, Volume: 16, Issue:4 Topics: Actinomycetales; Adenosine; Anti-Bacterial Agents; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Methyltransferases; Models, Molecular; Point Mutation; Protein Binding; Protein Multimerization; S-Adenosylhomocysteine; S-Adenosylmethionine; Teicoplanin	2009
S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases. The Journal of biological chemistry, 2009, Jul-17, Volume: 284, Issue:29 Topics: Adenosine; Catalytic Domain; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Methyltransferases; Models, Molecular; Molecular Structure; Mycobacterium; Mycobacterium tuberculosis; Mycolic Acids; Protein Binding; Protein Structure, Tertiary; S-Adenosylhomocysteine; S-Adenosylmethionine; Species Specificity	2009
Discrimination between closely related cellular metabolites by the SAM-I riboswitch. Journal of molecular biology, 2010, Feb-26, Volume: 396, Issue:3 Topics: Adenosine; Base Pairing; Conserved Sequence; Crystallography, X-Ray; Kinetics; Models, Molecular; Mutation; Nucleic Acid Conformation; RNA, Bacterial; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine	2010
Structure and mechanism of the chalcogen-detoxifying protein TehB from Escherichia coli. The Biochemical journal, 2011, Apr-01, Volume: 435, Issue:1 Topics: Adenosine; Biocatalysis; Catalytic Domain; Chalcogens; Consensus Sequence; Crystallography, X-Ray; Drug Resistance, Bacterial; Escherichia coli K12; Escherichia coli Proteins; Kinetics; Methylation; Mutagenesis, Site-Directed; Mutant Proteins; Organoselenium Compounds; Protein Conformation; Recombinant Proteins; S-Adenosylhomocysteine; Sequence Alignment; Sequence Homology, Amino Acid; Tellurium	2011
Detecting S-adenosyl-L-methionine-induced conformational change of a histone methyltransferase using a homogeneous time-resolved fluorescence-based binding assay. Analytical biochemistry, 2012, Apr-01, Volume: 423, Issue:1 Topics: Adenosine; Azepines; Catalytic Domain; Chromatography, High Pressure Liquid; Fluorescent Dyes; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Kinetics; Protein Binding; Quinazolines; Recombinant Proteins; S-Adenosylhomocysteine; Tandem Mass Spectrometry; Time Factors	2012
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis. The Journal of biological chemistry, 2012, Oct-26, Volume: 287, Issue:44 Topics: Adenosine; Adenosine Triphosphate; Amino Acid Sequence; Bacillus cereus; Bacterial Proteins; Biotin; Carrier Proteins; Chromatography, Gel; Conserved Sequence; Escherichia coli; Fatty Acids; Genetic Complementation Test; Hydrogen-Ion Concentration; Methionine; Molecular Sequence Data; Protein O-Methyltransferase; S-Adenosylhomocysteine; S-Adenosylmethionine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity	2012
S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase. PloS one, 2013, Volume: 8, Issue:10 Topics: Adenosine; Cell Line; Enzyme Inhibitors; Flavivirus; Humans; Methyltransferases; Models, Molecular; Protein Binding; Protein Conformation; S-Adenosylhomocysteine; West Nile virus	2013
High-resolution structures of the SARS-CoV-2 2'- Science signaling, 2020, 09-29, Volume: 13, Issue:651 Topics: Adenosine; Betacoronavirus; Binding Sites; Catalytic Domain; Coronavirus Infections; COVID-19; Crystallography, X-Ray; Dimerization; Genes, Viral; Humans; Methylation; Methyltransferases; Models, Molecular; Open Reading Frames; Pandemics; Pneumonia, Viral; Protein Binding; Protein Conformation; RNA Cap Analogs; RNA Processing, Post-Transcriptional; RNA, Viral; S-Adenosylhomocysteine; S-Adenosylmethionine; SARS-CoV-2; Structure-Activity Relationship; Viral Nonstructural Proteins	2020