sincalide and thiosemicarbazide

sincalide has been researched along with thiosemicarbazide* in 2 studies

Other Studies

2 other study(ies) available for sincalide and thiosemicarbazide

Article	Year
Design of non-peptide CCK2 and NK1 peptidomimetics using 1-(2-nitrophenyl)thiosemicarbazide as a novel common scaffold. Bioorganic & medicinal chemistry letters, 2001, Mar-12, Volume: 11, Issue:5 A beta-turn overlay hypothesis has been used to transform the core scaffold of a selective non-peptide bradykinin B2 receptor antagonist into ligands specifically recognized by the CCK2 or NK1 receptors. Topics: Animals; Brain Chemistry; Drug Design; Enzyme Inhibitors; In Vitro Techniques; Ligands; Models, Molecular; Molecular Structure; Nitro Compounds; Peptides; Protein Conformation; Radioligand Assay; Receptors, Cholecystokinin; Receptors, Neurokinin-1; Semicarbazides	2001
Anticonvulsant effects of caerulein, cholecystokinin octapeptide (CCK-8) and diazepam against seizures produced in mice by harman, thiosemicarbazide and isoniazid. Neuroscience letters, 1981, Jul-02, Volume: 24, Issue:2 Caerulein, cholecystokinin octapeptide (CCK-8) and diazepam delayed the onset of seizures produced by harman and thiosemicarbazide (TSC). Caerulein had the potency of diazepam, whereas CCK-8 was less active by a factor of four. The convulsions induced by isoniazid (INH) were very resistant to both caerulein and diazepam; CCK-8 was not tested against isoniazid. Haloperidol did not influence the effect of TSC; it enhanced isoniazid-induced seizures, and antagonized the convulsant effect of harman. Topics: Animals; Anticonvulsants; Ceruletide; Cholecystokinin; Diazepam; Haloperidol; Harmine; Isoniazid; Male; Mice; Mice, Inbred Strains; Seizures; Semicarbazides; Sincalide	1981

Article

Year

Design of non-peptide CCK2 and NK1 peptidomimetics using 1-(2-nitrophenyl)thiosemicarbazide as a novel common scaffold.

Bioorganic & medicinal chemistry letters, 2001, Mar-12, Volume: 11, Issue:5

A beta-turn overlay hypothesis has been used to transform the core scaffold of a selective non-peptide bradykinin B2 receptor antagonist into ligands specifically recognized by the CCK2 or NK1 receptors.

Topics: Animals; Brain Chemistry; Drug Design; Enzyme Inhibitors; In Vitro Techniques; Ligands; Models, Molecular; Molecular Structure; Nitro Compounds; Peptides; Protein Conformation; Radioligand Assay; Receptors, Cholecystokinin; Receptors, Neurokinin-1; Semicarbazides

2001

Anticonvulsant effects of caerulein, cholecystokinin octapeptide (CCK-8) and diazepam against seizures produced in mice by harman, thiosemicarbazide and isoniazid.

Neuroscience letters, 1981, Jul-02, Volume: 24, Issue:2

Caerulein, cholecystokinin octapeptide (CCK-8) and diazepam delayed the onset of seizures produced by harman and thiosemicarbazide (TSC). Caerulein had the potency of diazepam, whereas CCK-8 was less active by a factor of four. The convulsions induced by isoniazid (INH) were very resistant to both caerulein and diazepam; CCK-8 was not tested against isoniazid. Haloperidol did not influence the effect of TSC; it enhanced isoniazid-induced seizures, and antagonized the convulsant effect of harman.

Topics: Animals; Anticonvulsants; Ceruletide; Cholecystokinin; Diazepam; Haloperidol; Harmine; Isoniazid; Male; Mice; Mice, Inbred Strains; Seizures; Semicarbazides; Sincalide

1981