sincalide and decabromobiphenyl-ether

In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this study were the PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. The results may contribute to understanding the mechanism of PBDE-209 in immune function.

Topics: Animals; Cell Survival; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Halogenated Diphenyl Ethers; Immune System; Immunoglobulin M; Interferon-gamma; Interleukin-4; Lactation; Maternal Exposure; Organ Size; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sincalide