Page last updated: 2024-08-23

simvastatin and osteoprotegerin

simvastatin has been researched along with osteoprotegerin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's10 (71.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Chihara, K; Kaji, H; Kanatani, M; Sugimoto, T1
Celińska-Löwenhoff, M; Gluszko, P; Löwenhoff, T; Undas, A1
Dollerup, J; Gormsen, LC; Mogensen, CE; Nellemann, B; Nielsen, S; Rasmussen, LM; Schmitz, O1
Chen, C; Chen, Y; Han, G; Hou, J; Liu, C; Meng, W; Zhuang, J1
Liu, ST; Liu, ZH; Lu, ZS; Sun, HC; Xiaohui, RF; Zong, XM1
Dean, IN; Rawal, SY; Stein, SH; Tipton, DA1
Andrukhov, O; Bertl, K; Liu, S; Liu, ZH; Rausch-Fan, X; Sun, H1
Brito, GA; Dalcico, R; de Menezes, AM; Deocleciano, OB; Oriá, RB; Ribeiro, RA; Vale, ML1
Khademi, A; Shadmehr, E1
Bravo, M; Magán-Fernández, A; Marfil-Álvarez, R; Mesa, F; Papay-Ramírez, L; Rizzo, M; Tomás, J1
Bauer, I; Bertolotto, M; Dallegri, F; Fabre, M; Galan, K; Lenglet, S; Mach, F; Montecucco, F; Nencioni, A; Palombo, D; Pane, B; Pelli, G; Pende, A; Python, M; Quercioli, A; Spinella, G; Vuilleumier, N1
Brinchmann, JE; Haugen, HJ; Ostrup, E; Pullisaar, H; Reseland, JE1
Amin, RM; El-Khatib, AS; Elmazar, MM; Khattab, MM; Raafat, SN1
Abdollahi Kordkandi, S; Babaheidarian, P; Hajializade, M; Mirzaei, A; Moghtadaei, M; Pazoki-Toroudi, H; Yeganeh, A1

Trials

2 trial(s) available for simvastatin and osteoprotegerin

ArticleYear
Effects of hypolipemic drugs on the osteoprotegerin - sRANKL system in patients with coronary artery disease.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:5

    Topics: Bone Density; Coronary Artery Disease; Double-Blind Method; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Middle Aged; Osteoprotegerin; RANK Ligand; Simvastatin; Solubility

2007
Simvastatin reduces plasma osteoprotegerin in type 2 diabetic patients with microalbuminuria.
    Diabetes care, 2007, Volume: 30, Issue:12

    Topics: Albuminuria; Atherosclerosis; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Osteoprotegerin; Simvastatin

2007

Other Studies

12 other study(ies) available for simvastatin and osteoprotegerin

ArticleYear
Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2005, Volume: 37, Issue:10

    Topics: Animals; Bone Resorption; Calcitriol; Carrier Proteins; Cell Differentiation; Cells, Cultured; Glycoproteins; Lovastatin; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Osteoclasts; Osteogenesis; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; RNA, Messenger; Simvastatin

2005
Effects of simvastatin on relapse and remodeling of periodontal tissues after tooth movement in rats.
    American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics, 2010, Volume: 138, Issue:5

    Topics: Alveolar Process; Animals; Bone Density Conservation Agents; Bone Remodeling; Fibroblasts; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mandible; Models, Dental; Molar; Orthodontic Wires; Osteoblasts; Osteoclasts; Osteogenesis; Osteoprotegerin; Periodontal Ligament; Periodontium; Random Allocation; RANK Ligand; Rats; Rats, Wistar; Recurrence; Simvastatin; Stress, Mechanical; Time Factors; Tooth Movement Techniques

2010
[Effect of simvastatin on the function of MG63 cell line].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2010, Volume: 19, Issue:6

    Topics: Bone Regeneration; Cell Line; Cell Proliferation; Humans; Osteoblasts; Osteocalcin; Osteoprotegerin; Simvastatin

2010
Statins regulate interleukin-1β-induced RANKL and osteoprotegerin production by human gingival fibroblasts.
    Journal of periodontal research, 2011, Volume: 46, Issue:4

    Topics: Atorvastatin; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Culture Media, Serum-Free; Fibroblasts; Gingiva; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1beta; Osteoprotegerin; Pyrroles; RANK Ligand; Simvastatin; Temperature; Tetrazolium Salts; Thiazoles; Time Factors

2011
Effect of simvastatin on the osteogenetic behavior of alveolar osteoblasts and periodontal ligament cells.
    Human cell, 2012, Volume: 25, Issue:2

    Topics: Adult; Alkaline Phosphatase; Alveolar Process; Anticholesteremic Agents; Bone Regeneration; Cell Survival; Cells, Cultured; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Osteoblasts; Osteocalcin; Osteogenesis; Osteoprotegerin; Periodontal Ligament; RANK Ligand; Simvastatin; Time Factors

2012
Protective mechanisms of simvastatin in experimental periodontal disease.
    Journal of periodontology, 2013, Volume: 84, Issue:8

    Topics: Alanine Transaminase; Alkaline Phosphatase; Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Bone Morphogenetic Protein 2; Female; Gingiva; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-10; Interleukin-1beta; Malondialdehyde; Matrix Metalloproteinase 1; Matrix Metalloproteinase 8; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Osteoprotegerin; Oxidative Stress; Periodontitis; Peroxidase; RANK Ligand; Rats; Rats, Wistar; Receptor Activator of Nuclear Factor-kappa B; Simvastatin; Tumor Necrosis Factor-alpha

2013
Effect of simvastatin on kinetics of osteoprotegrin/receptor activator nuclear kappa B Ligand mRNA expression in periapical lesions.
    International endodontic journal, 2013, Volume: 46, Issue:11

    Topics: Animals; Kinetics; Ligands; Male; Osteoprotegerin; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Simvastatin

2013
Association of simvastatin and hyperlipidemia with periodontal status and bone metabolism markers.
    Journal of periodontology, 2014, Volume: 85, Issue:10

    Topics: Adult; Aged; Alcohol Drinking; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Collagen Type I; Cross-Sectional Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Osteocalcin; Osteoprotegerin; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Procollagen; Simvastatin; Smoking; Triglycerides

2014
Statin treatment is associated with reduction in serum levels of receptor activator of NF-κB ligand and neutrophil activation in patients with severe carotid stenosis.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Aged; Atherosclerosis; Atorvastatin; Carotid Stenosis; Cohort Studies; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matrix Metalloproteinase 9; Middle Aged; Neutrophil Activation; Neutrophils; NF-kappa B; Osteopontin; Osteoprotegerin; Pyrimidines; Pyrroles; RANK Ligand; Risk Factors; RNA, Messenger; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2014
Simvastatin coating of TiO₂ scaffold induces osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells.
    Biochemical and biophysical research communications, 2014, Apr-25, Volume: 447, Issue:1

    Topics: Adipose Tissue; Adult; Cell Differentiation; Cell Survival; Collagen Type I, alpha 1 Chain; Female; Humans; Mesenchymal Stem Cells; Middle Aged; Osteocalcin; Osteogenesis; Osteopontin; Osteoprotegerin; RNA, Messenger; Simvastatin; Tissue Engineering; Tissue Scaffolds; Titanium; Vascular Endothelial Growth Factor A

2014
The sole and combined effect of simvastatin and platelet rich fibrin as a filling material in induced bone defect in tibia of albino rats.
    Bone, 2018, Volume: 117

    Topics: Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Humans; Male; Osteocalcin; Osteoprotegerin; Platelet-Rich Fibrin; RANK Ligand; Rats; Simvastatin; Tibia; Vascular Endothelial Growth Factor A

2018
Significant effect of simvastatin and/or ezetimibe-loaded nanofibers on the healing of femoral defect: An experimental study.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 111

    Topics: Animals; Bone Density; Ezetimibe; Femur; Fracture Healing; Male; Nanofibers; Osteoprotegerin; Rats, Wistar; Simvastatin

2020