simvastatin has been researched along with cholestyramine resin in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (17.39) | 18.7374 |
| 1990's | 46 (66.67) | 18.2507 |
| 2000's | 11 (15.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alessandri, C; Peverini, F | 1 |
| Lundh, BL; Mölgaard, J; Olsson, AG; von Schenck, H | 1 |
| Antonicelli, R; Ippoliti, PF; Leone, L | 1 |
| Gallagher, JJ; Maher, VM; Myant, NB; Thompson, GR | 1 |
| Schlienger, JL | 1 |
| Kuijpens, JL; Martens, LL; Rutten, FF; Winter, J | 1 |
| Abate, N; Bertolotti, M; Carubbi, F; Carulli, N; Digrisolo, A; Dilengite, M; Loria, P; Pinetti, A | 1 |
| Beynen, AC; Haller, M; Meijer, GW; Van Lith, HA | 1 |
| Bo, M; Fabris, F; Fiandra, U; Pedrazzini, V; Pernigotti, L; Poli, L; Zanocchi, M | 1 |
| Erkelens, DW | 1 |
| Ascoop, CA; Erkelens, DW; Martens, LL; Rutten, FF | 2 |
| Maher, VM; Thompson, GR | 1 |
| Aubert, I; Bauduceau, B; Chanu, B; Dachet, C; Emmerich, J; Erlich, D; Gautier, D; Jacotot, B; Rouffy, J | 1 |
| Shapiro, DR; Walker, JF | 1 |
| Clifton, P; Cooper, ME; Jennings, GL; Jerums, G; Nestel, PJ; O'Brien, RC; Simons, LA; Sullivan, D | 1 |
| Burrichter, H; Geisel, J; Oette, K | 1 |
| Iizuka, Y; Ishida, F; Kakubari, K; Kamei, T; Kurahashi, Y; Sawasaki, Y | 1 |
| Demacker, PN; Mol, MJ; Stalenhoef, AF; Stuyt, PM | 1 |
| Kreisberg, R; Mantell, G; Miller, V; Shapiro, DR; Stein, E; Washington, L | 1 |
| Mölgaard, J; Olsson, AG; von Schenck, H | 1 |
| Lintott, CJ; Nye, ER; Robertson, MC; Scott, RS; Sutherland, WH | 1 |
| Mol, MJ; Stalenhoef, AF; Stuyt, PM | 2 |
| Nordøy, A; Ytre-Arne, K | 1 |
| Deslypere, JP | 1 |
| Iizuka, Y; Ishida, F; Kamei, T; Kitani, K; Sato, A; Sawasaki, Y | 1 |
| Erkelens, DW; Hené, RJ; Joles, JA; Koomans, HA; Rabelink, AJ | 1 |
| Aubert, I; Besseau, M; Chanu, B; Charpak, Y; Dachet, C; Emmerich, J; Herlich, D; Jacotot, B; Rouffy, J | 1 |
| Baggen, MG; Erkelens, DW; Kettner, M; Koningsberger, JC; Mol, MJ; Van Doormaal, JJ | 1 |
| Nikkilä, EA; Tikkanen, MJ | 1 |
| Olbricht, CJ | 1 |
| de Bruin, TW; Koomans, HA; Rabelink, TJ; Stroes, ES | 1 |
| Chin, JP; Dart, AM | 1 |
| Davies, G; Kitano, Y; Maher, VM; Matthews, S; Mir, A; Neuwirth, C; Prescott, RJ; Rees, A; Shortt, MB; Thompson, GR | 1 |
| Benhizia, F; Griglio, S; Lagrange, D; Malewiak, MI | 1 |
| Hodgson, JM; Marks, SJ; Matthews, PG; Myers, KA; Wahlqvist, ML | 1 |
| Buttery, PJ; Huggett, CD; Salter, AM | 1 |
| Fidge, N; Griffiths, P; Mitchell, A | 1 |
| Shand, JH; West, DW | 1 |
| Gudnason, V; Humphries, SE; Lloyd, JK; Muller, DP | 1 |
| Erkelens, DW; Portincasa, P; Renooij, W; Smit, JW; Van Berge-Henegouwen, GP; Van Erpecum, KJ | 1 |
| Auwerx, J; Fruchart, JC; Staels, B; Van Tol, A | 1 |
| Fidge, N; Mitchell, A | 1 |
| Boissonnat, P; de Lorgeril, M; Dureau, G; Monjaud, I; Salen, P | 1 |
| Ichikawa, M; Matsuyama, K; Nakai, A; Nishikata, M | 1 |
| Dotti, MT; Federico, A; Lindenthal, B; Lütjohann, D; Simatupang, A; von Bergmann, K | 1 |
| Cheung, J; Crook, MA; Lumb, PJ; Wierzbicki, AS | 1 |
| Barrett-Connor, E | 1 |
| Chijiiwa, K; Kishinaka, M; Kuroki, S; Shimura, H; Tanaka, M | 1 |
| Knight, BL; Patel, DD; Soutar, AK; Sun, XM | 1 |
| Celermajer, DS; Simons, J; Simons, LA; Sullivan, D | 1 |
| Beynen, AC; Groener, JE; Meijer, GW; Van Tol, A | 1 |
| Crook, MA; Lumb, PJ; Semra, YK; Wierzbicki, AS | 1 |
| Simons, LA | 1 |
| Hoogerbrugge, N | 1 |
| Benesch, L; Bestehorn, HP; Betz, P; Blümchen, G; Böcker, JF; Braunagel, K; Claus, J; Kappenberger, L; Kiefer, H; Leimenstoll, B; Mathes, P; Meister, G; Neiss, A; Peters, K; Petersen, J; Rensing, UF; Roskamm, H; Samek, L; Schemeitat, K; Schuon, J; Spinder, M; Stiepel, E; Wieland, H | 1 |
| McPherson, R | 1 |
| Barter, PJ; O'Brien, RC | 1 |
| Angius, MF; Brizzi, P; Carboni, A; Cherchi, GM; Ciccarese, M; Formato, M; Maioli, M; Melis, MG; Tonolo, G | 1 |
| Kersting, F; Selenka, A; Walch, S | 1 |
| Gylling, H; Miettinen, TA | 1 |
| Bouzamondo, A; Corvol, JC; Hulot, JS; Lechat, P; Sanchez, P; Sirol, M | 1 |
| Bertolotti, M; Carulli, L; Carulli, N; Del Puppo, M; Kienle, MG; Loria, P; Pinetti, A; Simonini, MS; Zambianchi, L | 1 |
| Mishra, TK; Routray, S | 1 |
| Borghi, C; Dormi, A; Gaddi, A; Sangiorgi, Z; Veronesi, M | 1 |
| Abaterusso, C; Abhyankar, A; Brocco, E; Carraro, A; Faedda, R; Luthman, H; Morgia, G; Nosadini, R; Satta, A; Tonolo, G; Velussi, M | 1 |
| Plans-Rubió, P | 1 |
| Anzivino, C; Bertolotti, M; Carulli, L; Carulli, N; Corna, F; Del Puppo, M; Gabbi, C; Kienle, MG; Loria, P; Pellegrini, E; Ricchi, M; Zambianchi, L | 1 |
5 review(s) available for simvastatin and cholestyramine resin
| Article | Year |
|---|---|
[Clinical evaluation of a selective inhibitor of cholesterol synthesis: pravastatin].
Topics: Adult; Animals; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Guinea Pigs; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Pravastatin; Rats; Risk Factors; Simvastatin; Time Factors | 1992 |
Efficacy and tolerability of simvastatin (MK-733).
Topics: Adrenal Cortex; Adult; Aged; Anticholesteremic Agents; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Simvastatin | 1989 |
Lowering cholesterol in patients with coronary heart disease: are we ready yet?
Topics: Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Coronary Disease; Humans; Hypolipidemic Agents; Simvastatin | 1997 |
Modulation of cholesterol metabolism affects tumor growth in hamsters.
Topics: Animals; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Cricetinae; DNA, Neoplasm; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mesocricetus; Neoplasm Transplantation; Neoplasms, Experimental; Simvastatin; Tumor Cells, Cultured | 1998 |
Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.
Topics: Anticholesteremic Agents; Atorvastatin; Cholestyramine Resin; Clofibrate; Colestipol; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Myocardial Infarction; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Risk Factors; Simvastatin; Stroke; Treatment Failure; Treatment Outcome | 2003 |
30 trial(s) available for simvastatin and cholestyramine resin
| Article | Year |
|---|---|
Long-term efficacy and safety of simvastatin alone and in combination therapy in treatment of hypercholesterolaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lens, Crystalline; Lipids; Liver; Lovastatin; Male; Middle Aged; Simvastatin | 1991 |
[Treatment of hypercholesterolemic patients of different age with simvastatin: 1-year study].
Topics: Adult; Age Factors; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Middle Aged; Simvastatin; Time Factors | 1991 |
HMG CoA reductase inhibitors as lipid-lowering agents: five years experience with lovastatin and an appraisal of simvastatin and pravastatin.
Topics: Adult; Aged; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Naphthalenes; Phenotype; Pravastatin; Simvastatin; Time Factors | 1990 |
Efficacy and safety of simvastatin (alone or in association with cholestyramine). A 1-year study in 66 patients with type II hyperlipoproteinaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Apoproteins; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hyperlipoproteinemia Type II; Lipids; Lovastatin; Male; Middle Aged; Simvastatin | 1990 |
Hydroxymethylglutaryl coenzyme A reductase inhibitors as monotherapy in the treatment of hypercholesterolemia.
Topics: Bezafibrate; Cholestyramine Resin; Double-Blind Method; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Probucol; Randomized Controlled Trials as Topic; Simvastatin | 1990 |
Comparison of simvastatin and cholestyramine in the treatment of primary hypercholesterolaemia.
Topics: Adult; Aged; Analysis of Variance; Anticholesteremic Agents; Australia; Cholesterol; Cholestyramine Resin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Simvastatin; Triglycerides | 1990 |
Effects of simvastatin and cholestyramine in familial and nonfamilial hypercholesterolemia. Multicenter Group I.
Topics: Adult; Alanine Transaminase; Anticholesteremic Agents; Cataract; Cholesterol; Cholestyramine Resin; Creatine Kinase; Female; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Simvastatin; Triglycerides | 1990 |
Comparative effects of simvastatin and cholestyramine in treatment of patients with hypercholesterolaemia.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Apoproteins; Cholestyramine Resin; Female; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Patient Compliance; Simvastatin; Time Factors | 1989 |
Simvastatin (MK 733): an effective treatment for hypercholesterolemia.
Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Random Allocation; Simvastatin | 1989 |
Simvastatin and cholestyramine in the long-term treatment of hypercholesterolaemia.
Topics: Adult; Aged; Alanine Transaminase; Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Lipids; Lovastatin; Male; Middle Aged; Random Allocation; Simvastatin; Time Factors | 1989 |
Comparison between low-dose simvastatin and cholestyramine in moderately severe hypercholesterolemia.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Administration Schedule; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Simvastatin | 1989 |
Effects of simvastatin and cholestyramine on lipoprotein profile in hyperlipidaemia of nephrotic syndrome.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins A; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipoproteins; Lovastatin; Male; Middle Aged; Nephrotic Syndrome; Random Allocation; Simvastatin | 1988 |
[Effects of simvastatin on plasma lipids, lipoproteins and apoproteins (A1 and B). 24 cases of major primary hypercholesterolemia].
Topics: Adult; Anticholesteremic Agents; Apoproteins; Cholestyramine Resin; Clinical Trials as Topic; Female; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged; Random Allocation; Simvastatin | 1988 |
Clinical experience with simvastatin compared with cholestyramine.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Female; Humans; Hyperlipoproteinemia Type II; Lipids; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides | 1988 |
HBPRCA Astra Award. Therapeutic restoration of endothelial function in hypercholesterolaemic subjects: effect of fish oils.
Topics: Acetylcholine; Adult; Australia; Awards and Prizes; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Endothelium, Vascular; Female; Fish Oils; Forearm; Humans; Hypercholesterolemia; Hypertension; Lovastatin; Male; Middle Aged; Regional Blood Flow; Simvastatin | 1994 |
Familial Hypercholesterolaemia Regression Study: a randomised trial of low-density-lipoprotein apheresis.
Topics: Adult; Blood Component Removal; Cholestyramine Resin; Colestipol; Coronary Angiography; Coronary Artery Disease; Data Interpretation, Statistical; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipids; Lipoprotein(a); Lipoproteins, LDL; Lovastatin; Middle Aged; Odds Ratio; Simvastatin | 1995 |
Effects of simvastatin and cholestyramine on bile lipid composition and gall bladder motility in patients with hypercholesterolaemia.
Topics: Anticholesteremic Agents; Bile; Cholesterol; Cholestyramine Resin; Drug Therapy, Combination; Female; Gallbladder; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Prospective Studies; Simvastatin; Ultrasonography | 1995 |
Fenofibrate plus simvastatin therapy versus simvastatin plus cholestyramine therapy for familial hypercholesterolaemia.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Middle Aged; Simvastatin; Triglycerides | 1997 |
Influence of genotype at the low density lipoprotein (LDL) receptor gene locus on the clinical phenotype and response to lipid-lowering drug therapy in heterozygous familial hypercholesterolaemia. The Familial Hypercholesterolaemia Regression Study Group.
Topics: Adult; Anticholesteremic Agents; Cholestyramine Resin; Colestipol; Female; Genotype; Heterozygote; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Male; Middle Aged; Phenotype; Receptors, LDL; Simvastatin | 1998 |
Effects of atorvastatin monotherapy and simvastatin plus cholestyramine on arterial endothelial function in patients with severe primary hypercholesterolaemia.
Topics: Adult; Anticholesteremic Agents; Arthralgia; Atorvastatin; Brachial Artery; Cholestyramine Resin; Drug Therapy, Combination; Endothelium, Vascular; Exanthema; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Lipids; Lipoproteins; Male; Middle Aged; Pyrroles; Simvastatin; Treatment Outcome; Ultrasonography | 1998 |
High-dose atorvastatin therapy in severe heterozygous familial hypercholesterolaemia.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, HDL; Cholestyramine Resin; Drug Administration Schedule; Drug Combinations; Fenofibrate; Heptanoic Acids; Heterozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Middle Aged; Pyrroles; Simvastatin; Triglycerides | 1998 |
Comparison of atorvastatin alone versus simvastatin +/- cholestyramine in the management of severe primary hypercholesterolaemia (the six cities study).
Topics: Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Combined Modality Therapy; Diet, Fat-Restricted; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Pyrroles; Simvastatin; Treatment Outcome; Triglycerides | 1998 |
Effects of atorvastatin on serum lipids of patients with familial hypercholesterolaemia.
Topics: Adult; Anticholesteremic Agents; Apolipoproteins; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipids; Male; Middle Aged; Niacin; Pyrroles; Simvastatin; Treatment Outcome; Triglycerides | 1998 |
[Lipid intervention and coronary heart disease in men less than 56 years of age. The Coronary Intervention Study: CIS].
Topics: Anticholesteremic Agents; Cholesterol, LDL; Cholestyramine Resin; Combined Modality Therapy; Coronary Angiography; Coronary Disease; Diet, Fat-Restricted; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Hypercholesterolemia; Male; Middle Aged; Prospective Studies; Simvastatin | 1999 |
Comparative effects of simvastatin and cholestyramine on plasma lipoproteins and CETP in humans.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholestyramine Resin; Female; Glycoproteins; Humans; Lipoproteins; Male; Middle Aged; Simvastatin | 1999 |
Achievement of target plasma cholesterol levels in hypercholesterolaemic patients being treated in general practice.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholestyramine Resin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Family Practice; Female; Follow-Up Studies; Heptanoic Acids; Humans; Hypercholesterolemia; Linear Models; Logistic Models; Male; Middle Aged; Pyrroles; Simvastatin; Treatment Outcome | 2000 |
Additive effects of Simvastatin beyond its effects on LDL cholesterol in hypertensive type 2 diabetic patients.
Topics: Albuminuria; Anticholesteremic Agents; Apolipoproteins; Blood Pressure; Cholesterol, LDL; Cholestyramine Resin; Diabetes Mellitus, Type 2; Female; Glycosaminoglycans; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitrites; Simvastatin | 2000 |
Effects of cholestyramine on vitamin E levels in patients treated with statins.
Topics: Adult; Aged; Anticholesteremic Agents; Antioxidants; Cholesterol, LDL; Cholestyramine Resin; Drug Interactions; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Indoles; Lovastatin; Male; Middle Aged; Naphthalenes; Pravastatin; Simvastatin; Vitamin E | 2000 |
Association between different lipid-lowering treatment strategies and blood pressure control in the Brisighella Heart Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure; Cholesterol, LDL; Cholestyramine Resin; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Male; Middle Aged; Prospective Studies; Simvastatin | 2004 |
Simvastatin maintains steady patterns of GFR and improves AER and expression of slit diaphragm proteins in type II diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albumins; Albuminuria; Anticholesteremic Agents; Cholestyramine Resin; Deoxyguanosine; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Humans; Kidney Glomerulus; Lipids; Male; Middle Aged; Podocytes; Proteins; RNA, Messenger; Simvastatin | 2006 |
34 other study(ies) available for simvastatin and cholestyramine resin
| Article | Year |
|---|---|
Use of simvastatin plus cholestyramine in the treatment of lysosomal acid lipase deficiency.
Topics: Child, Preschool; Cholesterol Ester Storage Disease; Cholestyramine Resin; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Simvastatin | 1991 |
Response to cholesterol-lowering drugs in familial defective apolipoprotein B-100.
Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein B-100; Apolipoproteins B; Apolipoproteins E; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Drug Therapy, Combination; Female; Heterozygote; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Phenotype; Simvastatin; Triglycerides | 1991 |
[Evaluation of the addition of fenofibrate to the simvastatin-cholestyramine combination].
Topics: Anticholesteremic Agents; Cholestyramine Resin; Drug Therapy, Combination; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Lovastatin; Simvastatin | 1991 |
[Cost-effectiveness of lowering of blood cholesterol using simvastatin and cholestyramine].
Topics: Adult; Age Factors; Anticholesteremic Agents; Cholestyramine Resin; Cost-Benefit Analysis; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Netherlands; Sex Factors; Simvastatin | 1991 |
Regulation of bile acid synthesis in humans: effect of treatment with bile acids, cholestyramine or simvastatin on cholesterol 7 alpha-hydroxylation rates in vivo.
Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Deoxycholic Acid; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Simvastatin; Ursodeoxycholic Acid | 1991 |
Serum pseudocholinesterase activity in rabbits fed simvastatin.
Topics: Animals; Anticholesteremic Agents; Butyrylcholinesterase; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Cholinesterase Inhibitors; Diet; Lovastatin; Male; Rabbits; Simvastatin | 1991 |
Combination drug therapy with HMG CoA reductase inhibitors and bile acid sequestrants for hypercholesterolemia.
Topics: Cholestyramine Resin; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipids; Lovastatin; Niacin; Simvastatin | 1990 |
Clinical benefits and cost-effectiveness of lowering serum cholesterol levels: the case of simvastatin and cholestyramine in The Netherlands.
Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Coronary Disease; Cost-Benefit Analysis; Female; Humans; Life Expectancy; Lovastatin; Male; Middle Aged; Netherlands; Risk Factors; Simvastatin | 1990 |
[HMG-CoA reductase inhibitors in familial hypercholesterolemia. Therapy with simvastatin alone and in combination with cholestyramine in low dosage; a report of 2 years experiences].
Topics: Adult; Anticholesteremic Agents; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Simvastatin | 1990 |
Effect of simvastatin (MK-733) on sterol and bile acid excretion in rabbits.
Topics: Animals; Bile; Bile Acids and Salts; Cholesterol, Dietary; Cholestyramine Resin; Feces; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Metabolism; Lipids; Liver; Lovastatin; Male; Rabbits; Simvastatin; Sterols | 1990 |
The effects of simvastatin on serum lipoproteins in severe hypercholesterolaemia.
Topics: Adult; Apolipoproteins; Cholesterol; Cholestyramine Resin; Colestipol; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides | 1990 |
Cost effectiveness of cholesterol-lowering therapy in The Netherlands. Simvastatin versus cholestyramine.
Topics: Adult; Anticholesteremic Agents; Cholestyramine Resin; Coronary Disease; Cost-Benefit Analysis; Female; Humans; Lovastatin; Male; Middle Aged; Netherlands; Simvastatin | 1989 |
Effects of MK-733 (simvastatin), an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on intestinal acylcoenzyme A:cholesterol acyltransferase activity in rabbits.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Cytosol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Absorption; Intestinal Mucosa; Lipids; Lovastatin; Male; Microsomes; Rabbits; Simvastatin; Sterol Esterase; Sterol O-Acyltransferase | 1989 |
[Efficacy and safety of simvastatin, a new cholesterol-lowering drug].
Topics: Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin | 1989 |
Current pharmacologic treatment of elevated serum cholesterol.
Topics: Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Drug Tolerance; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Probucol; Simvastatin; Triglycerides | 1987 |
Low-density-lipoprotein apheresis.
Topics: Anticholesteremic Agents; Blood Component Removal; Cholestyramine Resin; Colestipol; Combined Modality Therapy; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Lovastatin; Simvastatin | 1995 |
Vascular function in the forearm of hypercholesterolaemic patients off and on lipid-lowering medication.
Topics: Adult; Arginine; Blood Pressure; Cholesterol; Cholestyramine Resin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Forearm; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Infusions, Intravenous; Lovastatin; Male; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Serotonin; Simvastatin; Vasodilation | 1995 |
In vivo regulation of hepatic lipase activity and mRNA levels by diets which modify cholesterol influx to the liver.
Topics: Animals; Body Weight; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Cholic Acid; Cholic Acids; Diet; Female; Hydroxymethylglutaryl CoA Reductases; Lipase; Lipid Metabolism; Lipids; Liver; Lovastatin; Rats; Rats, Zucker; RNA, Messenger; Simvastatin | 1994 |
Improvement in arterial stiffness during hypolipidaemic therapy is offset by weight gain.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Arteries; Blood Pressure; Body Mass Index; Carotid Artery, Common; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Dietary Fats; Female; Femoral Artery; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Niacin; Simvastatin; Triglycerides; Ultrasonography; Weight Gain | 1993 |
Plasma VLDL cholesterol and egg cholesterol are resistant to change in the laying hen.
Topics: Animals; Chickens; Cholesterol; Cholesterol, VLDL; Cholestyramine Resin; Eggs; Hydroxymethylglutaryl CoA Reductases; Ketocholesterols; Lovastatin; Simvastatin | 1993 |
The effect of the HMG-CoA reductase inhibitor simvastatin and of cholestyramine on hepatic apolipoprotein mRNA levels in the rat.
Topics: Animals; Apolipoproteins; Apolipoproteins B; Cholestyramine Resin; Gene Expression; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Rats; RNA, Messenger; Simvastatin | 1993 |
The effects of simvastatin and cholestyramine, alone and in combination, on hepatic cholesterol metabolism in the male rat. off.
Topics: Animals; Cholesterol; Cholestyramine Resin; Cytosol; Diet; Enzyme Inhibitors; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Lovastatin; Male; Microsomes, Liver; Rats; Rats, Wistar; Simvastatin; Sterol Esterase; Sterol O-Acyltransferase | 1995 |
Response to drugs and diet in a compound heterozygote for familial hypercholesterolaemia.
Topics: Base Sequence; Blotting, Southern; Child; Cholestyramine Resin; Combined Modality Therapy; Diet, Fat-Restricted; Dietary Fats; Drug Therapy, Combination; Heterozygote; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Molecular Sequence Data; Mutation; Pedigree; Receptors, LDL; Simvastatin | 1995 |
Effects of hypolipidemic drugs on the expression of genes involved in high density lipoprotein metabolism in the rat.
Topics: Actins; Animals; Apolipoproteins; Cholestyramine Resin; Clofibrate; Fenofibrate; Gene Expression Regulation; Hypolipidemic Agents; Intestinal Mucosa; Lipid Metabolism; Lipoproteins, HDL; Liver; Lovastatin; Male; Niacin; Probucol; Rats; Rats, Wistar; Simvastatin | 1996 |
Determination of apolipoprotein mRNA levels by ribonuclease protection assay.
Topics: Animals; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Cholestyramine Resin; DNA, Complementary; Genetic Vectors; Lipase; Liver; Lovastatin; Rats; Ribonucleases; RNA Probes; RNA, Antisense; RNA, Double-Stranded; RNA, Messenger; RNA, Transfer; Simvastatin | 1996 |
Fenofibrate, probucol, and other lipid-lowering treatments in heart transplant recipients.
Topics: Anticholesteremic Agents; Cholestyramine Resin; Cyclosporine; Drug Interactions; Fenofibrate; Gemfibrozil; Heart Transplantation; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Lovastatin; Probucol; Simvastatin | 1996 |
Drug interaction between simvastatin and cholestyramine in vitro and in vivo.
Topics: Animals; Anticholesteremic Agents; Cholestyramine Resin; Chromatography, High Pressure Liquid; Drug Interactions; Drug Stability; Hydrolysis; Lovastatin; Male; Rats; Rats, Wistar; Simvastatin; Spectrophotometry, Ultraviolet | 1996 |
Urinary excretion of mevalonic acid as an indicator of cholesterol synthesis.
Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Circadian Rhythm; Female; Humans; Hypercholesterolemia; Lovastatin; Male; Mevalonic Acid; Middle Aged; Pravastatin; Reproducibility of Results; Simvastatin; Xanthomatosis, Cerebrotendinous | 1996 |
Lowering of serum cholesteryl ester transfer protein--but not lecithin:cholesterol acyltransferase--activity levels by hypocholesterolemic drugs in the rabbit.
Topics: Animals; Anticholesteremic Agents; Carrier Proteins; Cholesterol; Cholesterol Ester Transfer Proteins; Cholestyramine Resin; Glycoproteins; Lipoproteins; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Rabbits; Simvastatin | 1998 |
LDL cholesterol lowering by bile acid malabsorption during inhibited synthesis and absorption of cholesterol in hypercholesterolemic coronary subjects.
Topics: Aged; Anticholesteremic Agents; Bile Acids and Salts; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Coronary Artery Disease; Diet, Fat-Restricted; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Intestinal Absorption; Male; Simvastatin; Sitosterols; Treatment Outcome | 2002 |
Influence of newly synthesized cholesterol on bile acid synthesis during chronic inhibition of bile acid absorption.
Topics: Absorption; Aged; Bile Acids and Salts; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Simvastatin | 2003 |
Current perspectives on statins.
Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Coronary Artery Disease; Female; Humans; India; Lovastatin; Male; Middle Aged; Pravastatin; Randomized Controlled Trials as Topic; Simvastatin | 2003 |
Cost-effectiveness analysis of cholesterol-lowering therapies in Spain.
Topics: Anticholesteremic Agents; Atorvastatin; Cholesterol, LDL; Cholestyramine Resin; Clinical Trials as Topic; Coronary Disease; Cost-Benefit Analysis; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Indoles; Lovastatin; Meta-Analysis as Topic; Pravastatin; Pyrroles; Risk Factors; Simvastatin; Spain | 2006 |
Correlation between plasma levels of 7alpha-hydroxy-4-cholesten-3-one and cholesterol 7alpha-hydroxylation rates in vivo in hyperlipidemic patients.
Topics: Aged; Anticholesteremic Agents; Bezafibrate; Cholestenones; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Complement C4; Data Interpretation, Statistical; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Kinetics; Male; Middle Aged; Reference Standards; Simvastatin | 2008 |