Compounds > simvastatin acid
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simvastatin acid and pyrroles

simvastatin acid has been researched along with pyrroles in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hochman, JH; Lin, JH; Prueksaritanont, T; Pudvah, N; Qiu, J; Tang, C; Yamazaki, M1
Hirano, T; Iseki, K; Itagaki, S; Kobayashi, M; Otsuka, Y1
Caballero, R; Delpón, E; Gómez, R; Núñez, L; Tamargo, J; Vaquero, M1
Chen, C; Lin, J; Smolarek, T; Tremaine, L1
Bush, M; Collins, D; Generaux, G; Hussey, E; McMullen, S; Nunez, DJ; Polli, JW; Smith, G; Turner, N1
Kitzmiller, JP; Luzum, JA; Phelps, MA; Wang, J1

Trials

1 trial(s) available for simvastatin acid and pyrroles

ArticleYear
Evaluation of drug interactions of GSK1292263 (a GPR119 agonist) with statins: from in vitro data to clinical study design.
    Xenobiotica; the fate of foreign compounds in biological systems, 2013, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Atorvastatin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Demography; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Madin Darby Canine Kidney Cells; Male; Mesylates; Middle Aged; Oxadiazoles; Piperidines; Pyrimidines; Pyrroles; Reference Standards; Rosuvastatin Calcium; Simvastatin; Sulfonamides; Troleandomycin; Young Adult

2013

Other Studies

5 other study(ies) available for simvastatin acid and pyrroles

ArticleYear
Interactions of human P-glycoprotein with simvastatin, simvastatin acid, and atorvastatin.
    Pharmaceutical research, 2004, Volume: 21, Issue:9

    Topics: Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line; Drug Interactions; Heptanoic Acids; Humans; Hypolipidemic Agents; Pyrroles; Ritonavir; Simvastatin; Time Factors

2004
Inhibitory effects of statins on human monocarboxylate transporter 4.
    International journal of pharmaceutics, 2006, Jul-06, Volume: 317, Issue:1

    Topics: Animals; Atorvastatin; Basigin; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lactic Acid; LLC-PK1 Cells; Lovastatin; Monocarboxylic Acid Transporters; Muscle Proteins; Pyridines; Pyrroles; Simvastatin; Swine; Transfection

2006
Effects of atorvastatin and simvastatin on atrial plateau currents.
    Journal of molecular and cellular cardiology, 2007, Volume: 42, Issue:5

    Topics: Action Potentials; Animals; Atorvastatin; Cell Separation; CHO Cells; Cricetinae; Cricetulus; Heart Ventricles; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kv1.5 Potassium Channel; Male; Membrane Potentials; Mice; Myocytes, Cardiac; Pyrroles; Shal Potassium Channels; Simvastatin

2007
P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:10

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Brain; Heptanoic Acids; Lactones; Liver; Lovastatin; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Pravastatin; Pyrroles; Simvastatin

2007
Liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of simvastatin, lovastatin, atorvastatin, and their major metabolites in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Mar-01, Volume: 983-984

    Topics: Adult; Aged; Atorvastatin; Calibration; Chromatography, Liquid; Heptanoic Acids; Humans; Lovastatin; Middle Aged; Pyrroles; Quality Control; Reproducibility of Results; Simvastatin; Tandem Mass Spectrometry

2015