Page last updated: 2024-09-03

simplexin and fluorouracil

simplexin has been researched along with fluorouracil in 1 studies

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]

Compound Research Comparison

Studies
(simplexin)
Trials
(simplexin)
Recent Studies (post-2010)
(simplexin)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
50345,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomysimplexin (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hong, L; Ikejima, T; Li, F; Li, L; Peng, Y; Song, S; Sun, Q; Wu, Y; Xia, M1

Other Studies

1 other study(ies) available for simplexin and fluorouracil

ArticleYear
Daphnane-type diterpenes with inhibitory activities against human cancer cell lines from Daphne genkwa.
    Bioorganic & medicinal chemistry letters, 2013, May-01, Volume: 23, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Daphne; Diterpenes; Drug Screening Assays, Antitumor; Flowers; HCT116 Cells; HeLa Cells; Hep G2 Cells; HL-60 Cells; Humans; K562 Cells; Magnetic Resonance Spectroscopy; MCF-7 Cells; Molecular Conformation

2013