simethicone and urushiol

Eczematous skin disease is a serious work-related illness. Since 1995, reimbursement by insurance companies for treatment of skin diseases has become the largest cost source in some countries. This study was a randomized controlled trial (N = 20) of the efficacy of Pro-Q, a skin protectant product, in the prevention of contact dermatitis from sodium lauryl sulfate and urushiol, the resinous sap of poison ivy and poison oak. Pro-Q was significantly effective in reducing the irritation from sodium lauryl sulfate but did not prevent the allergic reaction to urushiol.

Topics: Administration, Cutaneous; Aerosols; Catechols; Dermatitis, Irritant; Dermatitis, Occupational; Dermatitis, Toxicodendron; Dermatologic Agents; Detergents; Dimethylpolysiloxanes; Double-Blind Method; Eczema; Glycerol; Humans; Irritants; Plants, Toxic; Protective Agents; Simethicone; Sodium Dodecyl Sulfate; Toxicodendron