simeprevir and cajanine

simeprevir has been researched along with cajanine* in 1 studies

Other Studies

1 other study(ies) available for simeprevir and cajanine

Article	Year
Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1. Journal of medicinal chemistry, 2016, 11-23, Volume: 59, Issue:22 There still remains a need to develop new anti-HCV agents with distinct mechanism of action (MOA) due to the occurrence of resistance to direct-acting antiviral agents (DAAs). Cajanine, a stilbenic component isolated from Cajanus cajan L., was identified as a potent HCV inhibitor by phenotypic screening in this work (EC Topics: Antiviral Agents; Diethylstilbestrol; Dose-Response Relationship, Drug; Down-Regulation; Drug Design; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepacivirus; Microbial Sensitivity Tests; Molecular Structure; N-Acetylgalactosaminyltransferases; Structure-Activity Relationship	2016

Article

Year

Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1.

Journal of medicinal chemistry, 2016, 11-23, Volume: 59, Issue:22

There still remains a need to develop new anti-HCV agents with distinct mechanism of action (MOA) due to the occurrence of resistance to direct-acting antiviral agents (DAAs). Cajanine, a stilbenic component isolated from Cajanus cajan L., was identified as a potent HCV inhibitor by phenotypic screening in this work (EC

Topics: Antiviral Agents; Diethylstilbestrol; Dose-Response Relationship, Drug; Down-Regulation; Drug Design; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepacivirus; Microbial Sensitivity Tests; Molecular Structure; N-Acetylgalactosaminyltransferases; Structure-Activity Relationship

2016