Compounds > simendan

Page last updated: 2024-08-24

simendan and pimobendan

simendan has been researched along with pimobendan in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (33.33)	18.2507
2000's	10 (55.56)	29.6817
2010's	2 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Etemadzadeh, E; Haikala, H; Levijoki, J; Lindén, IB; Nissinen, E	1
Haikala, H; Levijoki, J; Lindén, IB	1
Hettrick, DA; Pagel, PS; Warltier, DC	1
Haikala, H; Linden, IB	1
Katz, SD; Mathew, L	1
Bodi, A; Edes, I; Facsko, A; Kovacs, L; Kranias, EG; Kristof, E; Papp, JG; Papp, Z; Szigeti, G	1
Endoh, M	3
Chin, BS; Lip, GY	1
Boldt, J; Kirchner, J; Lehmann, A	1
Brixius, K; Schwinger, RH	1
Kaplinsky, EJ; Perrone, SV	1
Brixius, K; Hoyer, HK; Schwinger, RH	1
Izumi, T; Shinagawa, H	1
Iwama, Y; Takagi, A	1
Arai, M	1
Dong, W; Hu, D; Li, KL; Schlecht, W	1

Reviews

13 review(s) available for simendan and pimobendan

Article	Year
Mechanisms of action of calcium-sensitizing drugs. Journal of cardiovascular pharmacology, 1995, Volume: 26 Suppl 1 Topics: Animals; Calcium; Cardiotonic Agents; Humans; Hydrazones; Myocardial Contraction; Pyridazines; Quinolines; Sensitivity and Specificity; Simendan; Thiadiazines; Troponin C	1995
Calcium sensitising agents in heart failure. Drugs & aging, 1998, Volume: 12, Issue:3 Topics: Aged; Animals; Calcium; Cardiotonic Agents; Heart Failure; Humans; Hydrazones; Pyridazines; Simendan	1998
[Ca2+ sensitizers]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:6 Suppl Topics: Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Dihydropyridines; Drug Design; Heart Failure; Humans; Hydrazones; Myocardium; Pyridazines; Signal Transduction; Simendan	2000
New pharmacological strategies for the treatment of heart failure. Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:7 Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atrial Natriuretic Factor; Bosentan; Calcium; Cardiotonic Agents; Clinical Trials as Topic; Endothelin-1; Heart Failure; Humans; Hydrazones; Muscle Proteins; Neprilysin; Phosphodiesterase Inhibitors; Pyridazines; Simendan; Sulfonamides; Tumor Necrosis Factor-alpha	2001
Mechanism of action of Ca2+ sensitizers--update 2001. Cardiovascular drugs and therapy, 2001, Volume: 15, Issue:5 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Calcium; Calcium Signaling; Cardiac Output, Low; Cardiotonic Agents; Hemodynamics; Humans; Hydrazones; Myocardial Contraction; Pyridazines; Simendan	2001
The role of Ca++-sensitizers for the treatment of heart failure. Current opinion in critical care, 2003, Volume: 9, Issue:5 Topics: Calcium; Cardiotonic Agents; Chronic Disease; Clinical Trials as Topic; Dobutamine; Heart Failure; Hemodynamics; Humans; Hydrazones; Myocardial Ischemia; Pyridazines; Simendan	2003
[If the myofilaments become sensitive: Ca2+-sensitizer for the therapy of heart insufficiency]. Deutsche medizinische Wochenschrift (1946), 2005, Apr-15, Volume: 130, Issue:15 Topics: Actin Cytoskeleton; Calcium; Cardiotonic Agents; Heart; Heart Failure; Humans; Hydrazones; Myocardium; Oxygen Consumption; Pyridazines; Quinolines; Simendan; Thiadiazines	2005
Calcium sensitizer agents: a new class of inotropic agents in the treatment of decompensated heart failure. International journal of cardiology, 2005, Sep-01, Volume: 103, Issue:3 Topics: Arrhythmias, Cardiac; Cardiotonic Agents; Heart Failure; Humans; Hydrazones; Pyridazines; Simendan	2005
Ca2+-sensitisers--a promising option to treat heart failure? Cardiovascular drugs and therapy, 2005, Volume: 19, Issue:6 Topics: Calcium; Heart Failure; Humans; Hydrazones; Pyridazines; Simendan	2005
[Calcium sensitizer: characteristics, mechanisms of action, pharmacokinetics, indication, contraindication, clinical data, and side effects]. Nihon rinsho. Japanese journal of clinical medicine, 2007, May-28, Volume: 65 Suppl 5 Topics: Calcium; Cardiotonic Agents; Clinical Trials as Topic; Contraindications; Heart Failure; Humans; Hydrazones; Phosphodiesterase Inhibitors; Pyridazines; Simendan; Stimulation, Chemical; Survival Rate	2007
[Calcium sensitizer agents in heart failure therapy]. Nihon rinsho. Japanese journal of clinical medicine, 2007, May-28, Volume: 65 Suppl 5 Topics: Calcium; Cardiotonic Agents; Clinical Trials as Topic; Heart Failure; Humans; Hydrazones; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridazines; Simendan; Stimulation, Chemical	2007
Cardiac Ca2+ signaling and Ca2+ sensitizers. Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:12 Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Azocines; Calcium; Calcium Signaling; Cardiotonic Agents; Cholinergic Agonists; Dihydropyridines; Endothelins; Heart Failure; Humans; Hydrazones; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin C	2008
[Calcium mobilizers and calcium sensitizers]. Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 9 Topics: Calcium; Cardiotonic Agents; Heart Failure; Humans; Hydrazones; Myocardial Contraction; Pyridazines; Simendan	2011

Other Studies

5 other study(ies) available for simendan and pimobendan

Article	Year
Troponin C-mediated calcium sensitization induced by levosimendan does not impair relaxation. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:5 Topics: Adenosine Triphosphatases; Animals; Calcium; Cardiac Pacing, Artificial; Cardiotonic Agents; Cell Membrane; Female; Guinea Pigs; Hydrazones; Hydrogen-Ion Concentration; Male; Myocardial Contraction; Myofibrils; Papillary Muscles; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin; Troponin C; Vasodilator Agents	1995
Troponin C-mediated calcium sensitization by levosimendan accelerates the proportional development of isometric tension. Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:10 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Actomyosin; Animals; Calcium; Cardiotonic Agents; Cyclic Nucleotide Phosphodiesterases, Type 3; Guinea Pigs; Hydrazones; Isometric Contraction; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin; Troponin C	1995
Influence of levosimendan, pimobendan, and milrinone on the regional distribution of cardiac output in anaesthetized dogs. British journal of pharmacology, 1996, Volume: 119, Issue:3 Topics: Anesthesia; Animals; Cardiac Output; Dogs; Female; Hemodynamics; Hydrazones; Male; Milrinone; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Regional Blood Flow; Simendan	1996
Cardiac responses to calcium sensitizers and isoproterenol in intact guinea pig hearts. Effects on cyclic AMP levels, protein phosphorylation, myoplasmic calcium concentration, and left ventricular function. Annals of the New York Academy of Sciences, 1998, Sep-16, Volume: 853 Topics: Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Guinea Pigs; Heart; Hydrazones; Isoproterenol; Muscle Proteins; Myocardium; Phosphorylation; Pyridazines; Quinolines; Simendan; Thiadiazines; Ventricular Function, Left	1998
Fluorescence Based Characterization of Calcium Sensitizer Action on the Troponin Complex. Chemical biology & drug design, 2016, Volume: 87, Issue:2 Topics: Animals; Bepridil; Calcium; Cardiotonic Agents; Hydrazones; Kinetics; Mutagenesis, Site-Directed; Myocardium; Phosphorylation; Protein Binding; Pyridazines; Rats; Simendan; Spectrometry, Fluorescence; Troponin	2016