simendan has been researched along with emd 53998 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (63.64) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Etemadzadeh, E; Haikala, H; Levijoki, J; Lindén, IB; Nissinen, E | 1 |
| Haikala, H; Levijoki, J; Lindén, IB | 1 |
| Haikala, H; Linden, IB | 1 |
| Alpert, NR; Hasenfuss, G; Holubarsch, C; Just, H; Kretschmann, B; Pieske, B | 1 |
| Endoh, M; Sato, S; Sawada, H; Sugawara, H; Talukder, MA | 1 |
| Kleerekoper, Q; Putkey, JA | 1 |
| Bodi, A; Edes, I; Facsko, A; Kovacs, L; Kranias, EG; Kristof, E; Papp, JG; Papp, Z; Szigeti, G | 1 |
| Brixius, K; Schwinger, RH | 1 |
| Endoh, M | 1 |
| Ochala, J | 1 |
| Andersen, GØ; Ata, SH; Dahl, CP; Levy, FO; Orstavik, O; Osnes, JB; Qvigstad, E; Riise, J; Skomedal, T | 1 |
4 review(s) available for simendan and emd 53998
| Article | Year |
|---|---|
Mechanisms of action of calcium-sensitizing drugs.
Topics: Animals; Calcium; Cardiotonic Agents; Humans; Hydrazones; Myocardial Contraction; Pyridazines; Quinolines; Sensitivity and Specificity; Simendan; Thiadiazines; Troponin C | 1995 |
[If the myofilaments become sensitive: Ca2+-sensitizer for the therapy of heart insufficiency].
Topics: Actin Cytoskeleton; Calcium; Cardiotonic Agents; Heart; Heart Failure; Humans; Hydrazones; Myocardium; Oxygen Consumption; Pyridazines; Quinolines; Simendan; Thiadiazines | 2005 |
Cardiac Ca2+ signaling and Ca2+ sensitizers.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Azocines; Calcium; Calcium Signaling; Cardiotonic Agents; Cholinergic Agonists; Dihydropyridines; Endothelins; Heart Failure; Humans; Hydrazones; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin C | 2008 |
Ca2+ sensitizers: An emerging class of agents for counterbalancing weakness in skeletal muscle diseases?
Topics: Calcium; Calcium Signaling; Cardiotonic Agents; Contractile Proteins; Humans; Hydrazones; Muscle Weakness; Muscle, Skeletal; Muscular Diseases; Pyridazines; Quinolines; Simendan; Thiadiazines | 2010 |
7 other study(ies) available for simendan and emd 53998
| Article | Year |
|---|---|
Troponin C-mediated calcium sensitization induced by levosimendan does not impair relaxation.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cardiac Pacing, Artificial; Cardiotonic Agents; Cell Membrane; Female; Guinea Pigs; Hydrazones; Hydrogen-Ion Concentration; Male; Myocardial Contraction; Myofibrils; Papillary Muscles; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin; Troponin C; Vasodilator Agents | 1995 |
Troponin C-mediated calcium sensitization by levosimendan accelerates the proportional development of isometric tension.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Actomyosin; Animals; Calcium; Cardiotonic Agents; Cyclic Nucleotide Phosphodiesterases, Type 3; Guinea Pigs; Hydrazones; Isometric Contraction; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin; Troponin C | 1995 |
Effects of calcium sensitizers on intracellular calcium handling and myocardial energetics.
Topics: Adrenergic beta-Agonists; Aequorin; Animals; Calcium; Cardiotonic Agents; Energy Metabolism; Heart; Heart Ventricles; Humans; Hydrazones; In Vitro Techniques; Intracellular Fluid; Isometric Contraction; Isoproterenol; Male; Myocardial Contraction; Myocardium; Pyridazines; Quinolines; Rabbits; Sensitivity and Specificity; Simendan; Thiadiazines | 1995 |
Effects of levosimendan on myocardial contractility and Ca2+ transients in aequorin-loaded right-ventricular papillary muscles and indo-1-loaded single ventricular cardiomyocytes of the rabbit.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aequorin; Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Heart Ventricles; Hydrazones; Indoles; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Pyridazines; Quinolines; Rabbits; Simendan; Thiadiazines | 1998 |
Drug binding to cardiac troponin C.
Topics: Animals; Calcium; Hydrazones; Mice; Myocardial Contraction; Myocardium; Protein Conformation; Pyridazines; Quinolines; Simendan; Thiadiazines; Troponin C | 1999 |
Cardiac responses to calcium sensitizers and isoproterenol in intact guinea pig hearts. Effects on cyclic AMP levels, protein phosphorylation, myoplasmic calcium concentration, and left ventricular function.
Topics: Animals; Calcium; Cardiotonic Agents; Cyclic AMP; Guinea Pigs; Heart; Hydrazones; Isoproterenol; Muscle Proteins; Myocardium; Phosphorylation; Pyridazines; Quinolines; Simendan; Thiadiazines; Ventricular Function, Left | 1998 |
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Heart; Heart Failure; Humans; Hydrazones; In Vitro Techniques; Isoproterenol; Male; Milrinone; Myocardial Contraction; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Pyridazines; Quinolines; Quinolones; Rats, Wistar; Rolipram; Simendan; Thiadiazines | 2014 |