Page last updated: 2024-08-24

simendan and dobutamine

simendan has been researched along with dobutamine in 148 studies

Research

Studies (148)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (1.35)18.2507
2000's73 (49.32)29.6817
2010's58 (39.19)24.3611
2020's15 (10.14)2.80

Authors

AuthorsStudies
Akkila, J; Knuuti, MJ; Lehikoinen, P; Lehtonen, L; Någren, K; Saraste, M; Ukkonen, H; Voipio-Pulkki, LM1
Du Toit, EF; McCarthy, J; Muller, CA; Opie, LH1
Abdalla, M; Cleland, JG; Follath, F; Harjola, VP; Just, H; Lehtonen, L; Mitrovic, V; Papp, JG; Peuhkurinen, K; Sandell, EP; Scholz, H1
Apajasalo, M; Cleland, JG; Kobelt, G; Takala, A; Zethraeus, N1
Gattis, WA; Gheorghiade, M; Jain, P; Klein, L; Massie, BM1
Gronda, E; Mangiavacchi, M1
Nieminen, MS1
Boldt, J; Kirchner, J; Lehmann, A1
Follath, F1
Anifantakis, A; Athanassopoulos, G; Chatzigeorgiou, G; Cokkinos, DV; Iakovis, P; Karatasakis, G; Koutsogiannis, N; Manginas, A; Maounis, T; Papadakis, M; Spargias, KS1
De Santis, V; Mazzesi, G; Miraldi, F; Ozdem, SS; Papalia, U; Puddu, PE; Tritapepe, L; Usta, C; Vitale, D1
Agrios, N; Anastasiou-Nana, MI; Christodoulou, K; Dalianis, A; Kanakakis, J; Nanas, JN; Papazoglou, PP; Terrovitis, JV; Tsagalou, EP; Tsolakis, E1
Bornstein, SR; Fournell, A; Picker, O; Scheeren, TW; Schwarte, LA1
Coopersmith, CM1
Huang, L; Sun, S; Tang, W; Wang, J; Weil, MH1
Ayoub, IM; Gazmuri, RJ; Kolarova, JD1
Alexopoulos, GP; Anastasiou-Nana, MI; Kanakakis, J; Nanas, JN; Nanas, SN; Ntalianis, A; Papazoglou, P; Terrovitis, JV; Tsagalou, EP; Tsolakis, E1
Andreadou, I; Androulakis, A; Avgeropoulou, C; Demopoulou, M; Kallikazaros, I; Markantonis-Kyroudis, S; Missovoulos, P1
Barretto, AC; Canaviera, R; Follador, W; Martins, ML; Oliveira, MT; Scipioni, A; Tsuji, RL1
Reingardiene, D1
Barraud, D; Mebazaa, A; Welschbillig, S1
Cammarata, G; Cao, L; Huang, L; Sun, S; Tang, W; Weil, MH1
Camara, AK; Chen, Q; Pagel, PS; Rhodes, SS; Riess, ML; Ropella, KM; Stowe, DF1
Abreu-González, P; Domínguez-Rodríguez, A; Ferrer-Hita, JJ; García-González, MJ; Muñoz, MB1
Atar, D; Hodt, A; Steine, K1
Martos Fernández de Córdoba, F1
Alvarez, J; Bouzada, M; Caruezo, V; Fernández, AL; García-Bengoechea, JB; Ginesta, V; González-Juanatey, JR; Rodríguez, J; Rubio, J; Taboada, M1
Adamopoulos, S; Farmakis, D; Filippatos, GS; Gheorghiade, M; Iliodromitis, EK; Karatzas, D; Kremastinos, DT; Paraskevaidis, I; Parissis, JT; Tsiapras, D1
Hennersdorf, M; Müller, K; Peters, A; Strauer, BE; Zeus, T1
Brimioulle, S; Demester, JP; Fesler, P; Huez, S; Kerbaul, F; Naeije, R; Rondelet, B1
Barán, M; Canales, HS; Dubin, A; Edul, VS; Estenssoro, E; Etcheverry, G; Maskin, B; Murias, G; Pozo, MO; Sottile, JP1
Akilli, A; Akin, M; Duygu, H; Ergene, O; Nalbantgil, S; Nazli, C; Ozerkan, F; Zoghi, M1
Cavusoglu, Y1
Pagel, PS1
Cromheecke, S; De Hert, SG; Lorsomradee, S; Van der Linden, PJ1
Barraud, D; Damy, T; Faivre, V; Gayat, E; Heymes, C; Mebazaa, A; Payen, D; Shah, AM; Welschbillig, S1
Erdem, A; Karadas, F; Tandogan, I; Yilmaz, MB1
Cohen-Solal, A; Kivikko, M; Kleber, FX; Mebazaa, A; Nieminen, MS; Packer, M; Padley, RJ; Pocock, SJ; Põder, P; Thakkar, R1
Farmakis, D; Nieminen, M; Parissis, JT1
Kajimoto, K; Kawana, M; Watanabe, H1
Auriti, A; Cianfrocca, C; Guido, V; Li, X; Mercuro, G; Pasceri, V; Pelliccia, F; Richichi, G; Santini, M1
Abreu-González, P; Domínguez-Rodríguez, A; García-González, MJ; Samimi-Fard, S2
Butler, J; Giamouzis, G; Giannakoulas, G1
Ata, N; Birdane, A; Cavusoglu, Y; Demirustu, C; Gorenek, B; Tek, M; Timuralp, B; Unalir, A1
Buerke, M; Buerke, U; Carter, JM; Christoph, A; Lemm, H; Prondzinsky, R; Reith, S; Russ, MA; Schlitt, A; Söffker, G; Swyter, M; Wegener, N; Werdan, K; Winkler, M1
Akilli, A; Akin, M; Duygu, H; Ergene, O; Nalbantgil, S; Nazli, C; Ozerkan, F; Yildiz, A; Zoghi, M1
Erdem, A; Karadas, F; Tandogan, I; Turgut, OO; Yalta, K; Yilmaz, A; Yilmaz, MB; Yontar, C2
Banfor, PN; Campbell, TJ; Cox, BF; Fryer, RM; Marsh, KC; Polakowski, JS; Preusser, LC; Reinhart, GA1
Damman, K; Voors, AA1
Fryer, RM; Marsh, KC; Polakowski, JS; Segreti, JA1
Auriti, A; Cianfrocca, C; Guido, V; Mercuro, G; Pasceri, V; Pelliccia, F; Santini, M1
Blanco, N; Botbol, AL; Degrange, MA; del Mazo, CD; Levin, RL; Porcile, R; Salvagio, F; Tanus, E1
Agha, SA; Butler, J; Georgiopoulou, V; Giamouzis, G; Giannakoulas, G; Kalogeropoulos, A; Karvounis, H; Tsarpalis, K1
Celik, T; Iyisoy, A; Kardesoglu, E; Yuksel, UC1
Anastasiou-Nana, M; Dimopoulos, S; Gerovasili, V; Kaldara, E; Kourtidou, S; Nanas, J; Nanas, S; Pierrakos, C; Roussos, C; Sarafoglou, S; Venetsanakos, J1
Akyuz, S; Alioglu, E; Bozkaya, YT; Duygu, H; Gunduz, R; Kirilmaz, B; Ozdogan, O; Payzin, S; Turk, U; Turkoglu, C1
Bistola, V; Filippatos, G; Ikonomidis, I; Kremastinos, DT; Papadopoulos, C; Paraskevaidis, IA; Parissis, JT1
González-Costello, J; Homs, S1
Aydede, H; Erbüyün, K; Erhan, Y; Ok, G; Tekin, I; Tok, D; Türköz, E; Vatansever, S1
Akilli, A; Akin, M; Duygu, H; Ergene, O; Erturk, U; Nalbantgil, S; Nazli, C; Ozerkan, F; Zoghi, M1
Mebazaa, A; Paraskevaidis, I; Parissis, JT; Rafouli-Stergiou, P1
Cleland, JG; Cohen-Solal, A; Filippatos, GS; Huang, B; Mebazaa, A; Nieminen, MS; Padley, RJ; Salon, JE; Thakkar, R1
Bonios, M; Drakos, SG; Kaldara, E; Kanakakis, JV; Katsaros, F; Nanas, JN; Nanas, S; Pantsios, C1
Akilli, A; Akin, M; Duygu, H; Nalbantgil, S; Ozerkan, F; Yildiz, A; Zoghi, M1
Baumert, JH; Hein, M; Roehl, AB; Rossaint, R; Scherer, K; Steendijk, P1
Chay Woodward, T; de Lissovoy, G; Fraeman, K; Salon, J; Sterz, R1
Cai, D; Cohen-Solal, A; Huang, B; Logeart, D; Mebazaa, A; Nieminen, MS1
Abdullah, GM; Alhashemi, JA; Alotaibi, QA; Shalabi, SA1
Ackermann, D; Grottke, O; Hein, M; Rieg, AD; Rossaint, R; Schälte, G; Schroth, SC1
Blomquist, S; Cunha-Goncalves, D; Larsson, A; Perez-de-Sa, V; Thörne, J1
Kiviniemi, V; Kurola, J; Leppikangas, H; Lindgren, L; Ruokonen, E; Rutanen, J1
Bilgehan, K; Duman, D; Palit, F; Sacide, A; Simsek, E1
Cas, LD; Cotter, G; Gheorghiade, M; Metra, M; Sabbah, HN; Teerlink, JR; Zacà, V1
Yalta, K; Yilmaz, MB; Yontar, OC2
Geilfus, D; Graf, BM; Missler, G; Sinner, B; Zausig, YA; Zink, W1
Hermansen, SE; How, OJ; Jakobsen, Ø; Müller, S; Myrmel, T; Røsner, A; Stenberg, TA1
Omerovic, E; Swedberg, K; Waagstein, F1
Andersson, B; Bergh, CH; Dahlström, U; Forfang, K; Kivikko, M; Sarapohja, T; Ullman, B; Wikström, G1
Abroug, F; Dachraoui, F; Dimassi, S; Mebazaa, A; Ouanes, I; Ouanes-Besbes, L1
Alexander, PM; Butt, WW; Penny, DJ; Ryerson, LM; Shann, FA; Shekerdemian, LS1
Campia, U; Gheorghiade, M; Nodari, S1
Wikström, BG1
Ayub-Ferreira, SM; Bacal, F; Bocchi, EA; Mangini, S; Marcondes-Braga, FG1
Cui, L; Hao, YM; Jiang, DJ; Li, GP; Li, HM; Liu, J; Qi, GX; Wang, L; Wang, WZ; Wei, JP; Zhang, YD1
Erdem, A; Tandogan, I; Yalta, K; Yilmaz, MB; Yontar, OC1
Anastasiou-Nana, M; Bistola, V; Ikonomidis, I; Papadopoulos, C; Paraskevaidis, IA; Parissis, J; Stassinos, V1
Ata, N; Birdane, A; Cavuşoğlu, Y; Demirüstü, C; Göktekin, Ö; Görenek, B; Tek, M; Ünalır, A1
Böhm, M; Cai, D; Cohen Solal, A; Filippatos, GS; Huang, B; Kivikko, M; Link, A; Mebazaa, A; Nieminen, MS; Padley, RJ; Salem, R1
Bettari, L; Bugatti, S; Carubelli, V; Danesi, R; Dei Cas, L; Lazzarini, V; Lombardi, C; Metra, M; Monti, A; Villa, C1
Brasolin, B; Bruno, N; Caira, C; D'Ambrosi, A; Fedele, F; Mancone, M1
Läer, S; Vogt, W1
Inal, MT; Memiş, D; Sut, N1
Jovicić, B; Kosutić, J; Nikolić, L; Prijić, S; Rakić, S; Stajević, M; Vukomanović, V1
Borlu, F; Dal, MS; Oztekin, E; Paksoy, F; Tursun, I; Ulaş, T1
Fournell, A; Picker, O; Scheeren, TW; Schwarte, LA1
Noori, S; Seri, I1
An, T; Huang, Y; Lü, R; Qing, EM; Qing, P; Wei, BQ; Zhang, J; Zhang, YH; Zhou, Q; Zou, CH1
Bai, XJ; Huang, Y; Jiang, YN; Li, H; Liu, WX; Qing, EM; Qu, P; Sun, YX; Wei, BQ; Zhang, J; Zhang, L; Zhang, YH; Zhou, Q1
Amir, O; Zafrir, B1
Cai, D; Cohen-Solal, A; Deye, N; Kivikko, M; Laribi, S; Laterre, PF; Mebazaa, A; Nikolaou, M; Parissis, J; Paugam-Burtz, C; Poder, P; Pohjanjousi, P; Seronde, MF; Yilmaz, MB1
Ebade, AA; Khalil, MA; Mohamed, AK1
Apajasalo, M; D'Ambrosi, A; Fedele, F; Lucioni, C; Mazzi, S; Pollesello, P1
Huang, LQ; Huang, X; Jiang, RL; Lei, S; Xia, GL; Zhi, YH; Zhu, MF1
Barrett, NA; Berry, WT; Hewson, RW; Langrish, CJ; McKenzie, CA1
Barrett, CJ; Beil, M; Budgett, DM; Fu, F; Guild, SJ; Malpas, SC; McCormick, D; Rigel, DF; Stehlin, E; Whalley, G1
Alvarez, J; Baluja, A; Caruezo, V; Castroagudin, J; Otero, P; Rial, M; Rodriguez, A; Rodriguez, I; Rodriguez, J; Selas, S; Taboada, M; Tome, S; Veiras, S1
Bacaksiz, A; Erdogan, E; Ergelen, M; Erturk, M; Karakurt, H; Sonmez, O; Tasal, A; Turfan, M; Uyarel, H; Vatankulu, MA1
Aleixandre, L; Cortell, J; Herrera, P; Loro, JM; Valera, F; Vicente, R1
Buerke, M; Haerting, J; Hirsch, K; Prondzinsky, R; Thiele, H; Unverzagt, S; Wachsmuth, L; Werdan, K1
Akturk, IF; Birant, A; Erturk, M; Karakurt, H; Kurtar Mansıroglu, A; Oner, E; Somuncu, MU; Uzun, F; Yalcin, AA; Yildirim, A1
Chivite, D; Corbella, X; Formiga, F1
Calabrò, MG; Covello, RD; Greco, M; Greco, T; Landoni, G; Morelli, A; Pasin, L; Zangrillo, A1
Burkhardt, BE; Rücker, G; Stiller, B1
Bignami, E; De Luca, M; Di Tomasso, N; Frau, G; Landoni, G; Likhvantsev, V; Lomivorotov, V; Monaco, F; Oriani, A; Putzu, A; Zangrillo, A1
Çavuşoğlu, Y; Demirtaş, S; Gencer, E; Güneş, H; Kalaycı, S; Korkmaz, Ş; Mert, UK; Mutlu, F; Özdemir, S; Şaşmaz, H; Yılmaz, MB1
Apajasalo, M; Bertranou, E; Heringlake, M; Kivikko, M; Mardiguian, S; Pollesello, P; Smare, C1
Ertl, G; Pauschinger, M; von Scheidt, W1
Harjola, VP; Kivikko, M; Nieminen, MS; Pollesello, P; Sarapohja, T; Tarvasmäki, T1
Hu, MH; Ji, CL; Lai, ZZ; Meng, JB; Tian, S; Xu, XJ; Zhang, G1
Angelini, GD; Belletti, A; Benedetto, U; Biondi-Zoccai, G; Landoni, G; Leggieri, C; Silvani, P; Zangrillo, A1
Ferjani, M; Hajjej, Z; Labbene, I; Meddeb, B; Morelli, A; Sellami, W1
Baidya, DK; Bhattacharjee, S; Maitra, S; Soni, KD1
Alaa, M; Leite, S; Leite-Moreira, AF; Lopes, L; Lourenço, AP; Oliveira-Pinto, J; Tavares-Silva, M1
Almeida, I; Caetano, F; Costa, M; Fernandes, A; Gonçalves, L; Madeira, M; Reis, L1
Frantz, S; Henrich, EC; Prondzinsky, R; Schumann, J; Strobl, H; Thiele, H; Unverzagt, S; Weiche, S; Werdan, K1
Apostolopoulou, SC; Kakava, F; Rammos, S; Tsoutsinos, A; Vagenakis, GA1
Anker, SD; Balligand, JL; Bauersachs, J; Brutsaert, D; Carrier, L; Chlopicki, S; Cleland, JG; de Boer, RA; de Keulenaer, G; Dietl, A; Eschenhagen, T; Fischmeister, R; Hamdani, N; Harjola, VP; Heinzel, FR; Heymans, S; Hilfiker-Kleiner, D; Holzmeister, J; Limongelli, G; Linke, WA; Lund, LH; Lyon, AR; Maack, C; Manstein, DJ; Masip, J; Mebazaa, A; Metra, M; Metzger, J; Mueller, C; Papp, Z; Pieske, B; Ponikowski, P; Ristić, A; Ruschitzka, F; Seferović, PM; Skouri, H; Tocchetti, CG; Yilmaz, MB; Zimmermann, WH1
Andersson, B; Bartfay, SE; Bergh, N; Bollano, E; Dahlberg, P; Gilljam, T; Hjalmarsson, C; Karason, K; Lannemyr, L; Ljungman, C; Ricksten, SE; Rundqvist, B1
Dempsey, E; Rabe, H1
Babik, B; Bayat, S; Fodor, GH; Habre, W; Peták, F1
Araújo, I; Campos, L; Cunha, GJL; Fernandes, L; Ferraz, M; Fonseca, C; Gomes, RV; Morais, R; Rocha, BML1
Chen, X; Lei, J; Liao, X; Qian, L; Zhang, S1
Bottio, T; Gerosa, G; Piperata, A1
Efremov, L; Frantz, S; Mikolajczyk, R; Schumann, J; Sedding, D; Tongers, J; Uhlig, K1
Filipiak, KJ; Gasecka, A; Jaguszewski, MJ; Szarpak, L1
Alvarez, J; Bettex, D; Bouchez, S; Fruhwald, S; Girardis, M; Grossini, E; Guarracino, F; Heringlake, M; Herpain, A; Pollesello, P; Toller, W; Tritapepe, L1
Filipiak, KJ; Gasecka, A; Jaguszewski, MJ; Szarpak, L; Targonski, R1
Belletti, A; Cassina, T; Clivio, S; Putzu, A1
Chen, J; Chen, WT; Lei, YY; Lin, XF; Liu, DH; Liu, YY; Ning, YL; Xian, SX; Yang, ZQ1
Cheng, Q; Guo, J; Zhang, X; Zhu, Y1
Hu, K; Mathew, R1
Chen, N; Cui, N; Ding, XX; Li, N; Sun, T; Wang, SH; Yu, ZB; Zhang, N1
Aydın, C; Kaplangoray, M1
Fang, X; Huang, P; Jin, H; Liu, F; Ma, Z; Wang, S1
Dong, N; Guo, Q; Lan, H; Li, C; Shi, J; Wang, G; Xiong, T; Zhang, J; Zheng, Q1

Reviews

30 review(s) available for simendan and dobutamine

ArticleYear
Current medical treatment for the exacerbation of chronic heart failure resulting in hospitalization.
    American heart journal, 2003, Volume: 145, Issue:2 Suppl

    Topics: Aged; Diuretics; Dobutamine; Enalaprilat; Female; Heart Failure; Hemodynamics; Hospitalization; Humans; Hydrazones; Injections, Intravenous; Male; Milrinone; Natriuretic Agents; Natriuretic Peptide, Brain; Nitroprusside; Pulmonary Wedge Pressure; Pyridazines; Renal Agents; Simendan; Vasodilator Agents

2003
[Inotropic agents in advanced and refractory heart failure].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2003, Volume: 4, Issue:1

    Topics: Cardiotonic Agents; Dobutamine; Dopamine; Drug Administration Schedule; Heart Failure; Humans; Hydrazones; Phosphodiesterase Inhibitors; Pyridazines; Simendan; Treatment Failure; Treatment Outcome

2003
The role of Ca++-sensitizers for the treatment of heart failure.
    Current opinion in critical care, 2003, Volume: 9, Issue:5

    Topics: Calcium; Cardiotonic Agents; Chronic Disease; Clinical Trials as Topic; Dobutamine; Heart Failure; Hemodynamics; Humans; Hydrazones; Myocardial Ischemia; Pyridazines; Simendan

2003
[The novelty in the treatment of heart failure].
    Medicina (Kaunas, Lithuania), 2005, Volume: 41, Issue:7

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Cardiotonic Agents; Child; Child, Preschool; Dobutamine; Heart Failure; Hemodynamics; Humans; Hydrazones; Infant; Infant, Newborn; Infusions, Intravenous; Injections, Intravenous; Middle Aged; Multicenter Studies as Topic; Pyridazines; Randomized Controlled Trials as Topic; Retrospective Studies; Simendan; Vasodilator Agents

2005
Randomized clinical trials with levosimendan.
    The American journal of cardiology, 2005, Sep-19, Volume: 96, Issue:6A

    Topics: Acute Disease; Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Hydrazones; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Syndrome

2005
[Medical and ventilatory treatment of acute heart failure].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2006, Mar-09, Volume: 126, Issue:6

    Topics: Acute Disease; Adrenergic beta-Agonists; Cardiotonic Agents; Continuous Positive Airway Pressure; Diuretics; Dobutamine; Furosemide; Heart Failure; Humans; Hydrazones; Isosorbide Dinitrate; Natriuretic Agents; Natriuretic Peptide, Brain; Nitric Oxide Donors; Oxygen Inhalation Therapy; Practice Guidelines as Topic; Pyridazines; Simendan; Vasodilator Agents

2006
The use of levosimendan in comparison and in combination with dobutamine in the treatment of decompensated heart failure.
    Expert opinion on pharmacotherapy, 2007, Volume: 8, Issue:5

    Topics: Aged; Biological Availability; Calcium Channels; Cardiotonic Agents; Dobutamine; Half-Life; Heart Failure; Hospitalization; Humans; Hydrazones; Prognosis; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Tissue Distribution; Treatment Outcome

2007
Classical inotropes and new cardiac enhancers.
    Heart failure reviews, 2007, Volume: 12, Issue:2

    Topics: Algorithms; Cardiotonic Agents; Dobutamine; Dopamine; Heart Failure; Humans; Hydrazones; Milrinone; Practice Guidelines as Topic; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Treatment Outcome

2007
[Combination therapy with PDE III inhibitor for heart failure].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, May-28, Volume: 65 Suppl 5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Chronic Disease; Clinical Trials as Topic; Cyclic Nucleotide Phosphodiesterases, Type 3; Dobutamine; Drug Therapy, Combination; Heart Failure; Humans; Hydrazones; Milrinone; Phosphodiesterase Inhibitors; Pyridazines; Simendan

2007
Agents with inotropic properties for the management of acute heart failure syndromes. Traditional agents and beyond.
    Heart failure reviews, 2009, Volume: 14, Issue:4

    Topics: Acute Disease; Cardiotonic Agents; Digoxin; Dobutamine; Etiocholanolone; Exercise Test; Heart Failure; Hemodynamics; Hospitals, Group Practice; Humans; Hydrazones; Prognosis; Pyrazines; Pyridazines; Quinolines; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Simendan; Treatment Outcome; Urea; Vasodilator Agents

2009
Neonatal blood pressure support: the use of inotropes, lusitropes, and other vasopressor agents.
    Clinics in perinatology, 2012, Volume: 39, Issue:1

    Topics: Cardiotonic Agents; Cardiovascular System; Dobutamine; Dopamine; Epinephrine; Hemodynamics; Humans; Hydrazones; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Milrinone; Pyridazines; Shock; Simendan; Vasoconstrictor Agents; Vasopressins

2012
Beta blocker therapy, decompensated heart failure, and inotropic interactions: current perspectives.
    The Israel Medical Association journal : IMAJ, 2012, Volume: 14, Issue:3

    Topics: Acute Disease; Adrenergic beta-Antagonists; Cardiotonic Agents; Chronic Disease; Dobutamine; Drug Interactions; Drug Therapy, Combination; Heart Failure; Hospitalization; Humans; Hydrazones; Phosphodiesterase Inhibitors; Practice Guidelines as Topic; Pyridazines; Simendan

2012
Levosimendan versus dobutamine in critically ill patients: a meta-analysis of randomized controlled trials.
    Journal of Zhejiang University. Science. B, 2013, Volume: 14, Issue:5

    Topics: Arrhythmias, Cardiac; Cardiotonic Agents; Comorbidity; Critical Illness; Dobutamine; Evidence-Based Medicine; Heart Failure; Humans; Hydrazones; Hypotension; Pyridazines; Randomized Controlled Trials as Topic; Risk Factors; Simendan; Survival Rate; Treatment Outcome

2013
Inotropic agents and vasodilator strategies for acute myocardial infarction complicated by cardiogenic shock or low cardiac output syndrome.
    The Cochrane database of systematic reviews, 2014, Jan-02, Issue:1

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Enoximone; Humans; Hydrazones; Myocardial Infarction; Nitric Oxide; Pyridazines; Randomized Controlled Trials as Topic; Shock, Cardiogenic; Simendan; Vasodilator Agents

2014
[Organ-protection therapy. A new therapeutic approach for acute heart failure?].
    Medicina clinica, 2014, Volume: 142 Suppl 1

    Topics: Acute Disease; Amides; Benzazepines; Cardio-Renal Syndrome; Dobutamine; Fumarates; Heart Failure; Humans; Hydrazones; Inflammation; Kaplan-Meier Estimate; Multicenter Studies as Topic; Natriuretic Peptide, Brain; Prognosis; Pyridazines; Randomized Controlled Trials as Topic; Recombinant Proteins; Relaxin; Simendan; Therapies, Investigational; Tolvaptan

2014
A Bayesian network meta-analysis on the effect of inodilatory agents on mortality.
    British journal of anaesthesia, 2015, Volume: 114, Issue:5

    Topics: Bayes Theorem; Cardiac Surgical Procedures; Critical Illness; Dobutamine; Enoximone; Humans; Hydrazones; Milrinone; Pyridazines; Simendan; Vasodilator Agents

2015
Prophylactic milrinone for the prevention of low cardiac output syndrome and mortality in children undergoing surgery for congenital heart disease.
    The Cochrane database of systematic reviews, 2015, Mar-25, Issue:3

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Heart Defects, Congenital; Humans; Hydrazones; Infant; Infant, Newborn; Milrinone; Postoperative Complications; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Syndrome; Time Factors

2015
Levosimendan reduces mortality in patients with severe sepsis and septic shock: A meta-analysis of randomized trials.
    Journal of critical care, 2015, Volume: 30, Issue:5

    Topics: Cardiotonic Agents; Dobutamine; Female; Humans; Hydrazones; Male; Middle Aged; Norepinephrine; Pyridazines; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan

2015
Long-term intravenous inotropes in low-output terminal heart failure?
    Clinical research in cardiology : official journal of the German Cardiac Society, 2016, Volume: 105, Issue:6

    Topics: Administration, Intravenous; Cardiac Output; Cardiac Output, Low; Cardiotonic Agents; Chi-Square Distribution; Dobutamine; Drug Administration Schedule; Heart Failure; Heart Transplantation; Humans; Hydrazones; Milrinone; Odds Ratio; Practice Guidelines as Topic; Pyridazines; Risk Factors; Simendan; Time Factors; Treatment Outcome; Waiting Lists

2016
The effect of vasoactive drugs on mortality in patients with severe sepsis and septic shock. A network meta-analysis of randomized trials.
    Journal of critical care, 2017, Volume: 37

    Topics: Arginine Vasopressin; Cardiotonic Agents; Dobutamine; Dopamine; Epinephrine; Humans; Hydrazones; Network Meta-Analysis; Norepinephrine; Odds Ratio; Pyridazines; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan; Treatment Outcome; Vasoconstrictor Agents; Vasopressins

2017
Levosimendan does not provide mortality benefit over dobutamine in adult patients with septic shock: A meta-analysis of randomized controlled trials.
    Journal of clinical anesthesia, 2017, Volume: 39

    Topics: Adult; Cardiotonic Agents; Dobutamine; Humans; Hydrazones; Intensive Care Units; Norepinephrine; Pyridazines; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic; Simendan

2017
Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.
    The Cochrane database of systematic reviews, 2018, 01-29, Volume: 1

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Cause of Death; Dobutamine; Enoximone; Humans; Hydrazones; Middle Aged; Myocardial Infarction; Nitric Oxide; Pyridazines; Randomized Controlled Trials as Topic; Shock, Cardiogenic; Simendan; Vasodilator Agents

2018
The Use of Cardiotonic Drugs in Neonates.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Adrenal Cortex Hormones; Asphyxia Neonatorum; Cardiotonic Agents; Dobutamine; Dopamine; Heart Defects, Congenital; Humans; Hypotension; Infant, Newborn; Intensive Care Units, Neonatal; Milrinone; Neonatal Sepsis; Norepinephrine; Persistent Fetal Circulation Syndrome; Shock; Simendan; Vasoconstrictor Agents; Vasopressins

2019
Network Meta-Analysis of the Safety of Drug Therapy for Cardiogenic Shock.
    Journal of healthcare engineering, 2020, Volume: 2020

    Topics: Aged; Disease Progression; Dobutamine; Dopamine; Epinephrine; Female; Hemodynamics; Humans; Male; Middle Aged; Milrinone; Natriuretic Peptide, Brain; Network Meta-Analysis; Norepinephrine; Patient Safety; Recombinant Proteins; Shock, Cardiogenic; Simendan; Treatment Outcome

2020
Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.
    The Cochrane database of systematic reviews, 2020, 11-05, Volume: 11

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Cause of Death; Dobutamine; Enoximone; Epinephrine; Humans; Hydrazones; Middle Aged; Myocardial Infarction; Nitric Oxide; Placebos; Pyridazines; Randomized Controlled Trials as Topic; Shock, Cardiogenic; Simendan; Vasodilator Agents

2020
An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety.
    Expert review of cardiovascular therapy, 2021, Volume: 19, Issue:4

    Topics: Adrenergic beta-Antagonists; Cardiac Surgical Procedures; Cardiotonic Agents; Critical Care; Dobutamine; Heart Failure; Hemodynamics; Humans; Shock, Cardiogenic; Simendan

2021
Efficacy and safety of levosimendan and dobutamine in heart failure: A systematic review and meta-analysis.
    Cardiology journal, 2021, Volume: 28, Issue:3

    Topics: Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Hydrazones; Pyridazines; Simendan; Treatment Outcome

2021
Levosimendan versus dobutamine for sepsis-induced cardiac dysfunction: a systematic review and meta-analysis.
    Scientific reports, 2021, 10-13, Volume: 11, Issue:1

    Topics: Disease-Free Survival; Dobutamine; Heart Diseases; Lactic Acid; Sepsis; Simendan; Stroke Volume; Survival Rate

2021
Inotrope and vasopressor use in cardiogenic shock: what, when and why?
    Current opinion in critical care, 2022, 08-01, Volume: 28, Issue:4

    Topics: Cardiotonic Agents; Dobutamine; Humans; Shock, Cardiogenic; Simendan; Vasoconstrictor Agents

2022
A Meta-Analysis of the Effects of Levosimendan on Cardiac Function and Outcomes in Patients with Sepsis.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:8

    Topics: Dobutamine; Humans; Hydrazones; Pyridazines; Sepsis; Shock, Septic; Simendan; Stroke Volume; Ventricular Function, Left

2023

Trials

47 trial(s) available for simendan and dobutamine

ArticleYear
Myocardial efficiency during calcium sensitization with levosimendan: a noninvasive study with positron emission tomography and echocardiography in healthy volunteers.
    Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:5

    Topics: Adult; Calcium; Carbon Radioisotopes; Cardiotonic Agents; Chromatography, High Pressure Liquid; Dobutamine; Echocardiography; Epinephrine; Feasibility Studies; Heart; Hemodynamics; Humans; Hydrazones; Male; Myocardial Contraction; Myocardium; Nitroprusside; Norepinephrine; Oxygen Consumption; Pyridazines; Simendan; Sympathomimetics; Tomography, Emission-Computed; Vasodilation; Vasodilator Agents

1997
Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial.
    Lancet (London, England), 2002, Jul-20, Volume: 360, Issue:9328

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Double-Blind Method; Female; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Simendan; Treatment Outcome

2002
Intravenous levosimendan treatment is cost-effective compared with dobutamine in severe low-output heart failure: an analysis based on the international LIDO trial.
    European journal of heart failure, 2003, Volume: 5, Issue:1

    Topics: Aged; Cardiac Output, Low; Cardiotonic Agents; Cost-Benefit Analysis; Dobutamine; Double-Blind Method; Europe; Female; Follow-Up Studies; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Length of Stay; Life Expectancy; Male; Middle Aged; Patient Admission; Pyridazines; Randomized Controlled Trials as Topic; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Simendan; Survival Analysis; Treatment Outcome

2003
Levosimendan compared with dobutamine in low output patients.
    Minerva anestesiologica, 2003, Volume: 69, Issue:4

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Double-Blind Method; Hemodynamics; Humans; Hydrazones; Pulmonary Wedge Pressure; Pyridazines; Simendan

2003
Levosimendan in patients with low-output heart failure: lessons from the LIDO trial.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2003, Volume: 4 Suppl 2

    Topics: Adrenergic beta-Agonists; Calcium Channels, L-Type; Cardiac Output, Low; Cardiotonic Agents; Death, Sudden, Cardiac; Dobutamine; Dose-Response Relationship, Drug; Double-Blind Method; Europe; Heart Failure; Heart Rate; Humans; Hydrazones; Infusions, Intravenous; Morbidity; Myocardial Contraction; Pulmonary Wedge Pressure; Pyridazines; Risk Factors; Severity of Illness Index; Shock, Cardiogenic; Simendan; Stroke Volume; Survival Analysis; Time; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Left

2003
Hemodynamic effects of levosimendan added to dobutamine in patients with decompensated advanced heart failure refractory to dobutamine alone.
    The American journal of cardiology, 2004, Nov-15, Volume: 94, Issue:10

    Topics: Administration, Oral; Cardiac Output; Cardiotonic Agents; Diuretics; Dobutamine; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Pulmonary Wedge Pressure; Pyridazines; Simendan

2004
The Ca2+-sensitizer levosimendan improves oxidative damage, BNP and pro-inflammatory cytokine levels in patients with advanced decompensated heart failure in comparison to dobutamine.
    European journal of heart failure, 2005, Volume: 7, Issue:5

    Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Interleukin-6; Male; Malondialdehyde; Middle Aged; Natriuretic Peptide, Brain; Oxidative Stress; Pyridazines; Simendan; Time Factors; Tumor Necrosis Factor-alpha

2005
Cardiogenic shock after primary percutaneous coronary intervention: Effects of levosimendan compared with dobutamine on haemodynamics.
    European journal of heart failure, 2006, Volume: 8, Issue:7

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiac Output; Cardiotonic Agents; Dobutamine; Female; Humans; Hydrazones; Infusions, Intravenous; Middle Aged; Myocardial Infarction; Pyridazines; Shock, Cardiogenic; Simendan; Treatment Outcome

2006
[Hemodynamic effects of levosimendan compared with dobutamine in patients with low cardiac output after cardiac surgery].
    Revista espanola de cardiologia, 2006, Volume: 59, Issue:4

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Dobutamine; Female; Hemodynamics; Humans; Hydrazones; Male; Prospective Studies; Pyridazines; Simendan

2006
Effects of levosimendan versus dobutamine on inflammatory and apoptotic pathways in acutely decompensated chronic heart failure.
    The American journal of cardiology, 2006, Jul-01, Volume: 98, Issue:1

    Topics: Aged; Apoptosis; Cardiotonic Agents; Chronic Disease; Dobutamine; Echocardiography; Fas Ligand Protein; Female; Heart Failure; Hemodynamics; Humans; Hydrazones; Infusions, Intravenous; Interleukin-6; Male; Membrane Glycoproteins; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Pulmonary Wedge Pressure; Pyridazines; Simendan; Stroke Volume; Treatment Outcome; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors

2006
Effect of levosimendan on E/E' ratio in patients with ischemic heart failure.
    International journal of cardiology, 2008, Jan-11, Volume: 123, Issue:2

    Topics: Aged; Cardiotonic Agents; Dobutamine; Echocardiography, Doppler; Female; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Myocardial Ischemia; Prospective Studies; Pyridazines; Simendan; Single-Blind Method

2008
The effects of levosimendan in cardiac surgery patients with poor left ventricular function.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Adrenergic beta-Agonists; Aged; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; Dobutamine; Drug Administration Schedule; Drug Therapy, Combination; Elective Surgical Procedures; Female; Heart Diseases; Humans; Hydrazones; Intubation, Intratracheal; Length of Stay; Male; Middle Aged; Milrinone; Phosphodiesterase Inhibitors; Prospective Studies; Pyridazines; Simendan; Single-Blind Method; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function, Left

2007
Improvement in Doppler alternans in patients with severe heart failure: Levosimendan versus dobutamin.
    International journal of cardiology, 2008, Mar-28, Volume: 125, Issue:1

    Topics: Adult; Aged; Cardiotonic Agents; Dobutamine; Echocardiography, Doppler, Pulsed; Female; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Simendan; Ventricular Function, Left

2008
Levosimendan vs dobutamine for patients with acute decompensated heart failure: the SURVIVE Randomized Trial.
    JAMA, 2007, May-02, Volume: 297, Issue:17

    Topics: Acute Disease; Aged; Cardiotonic Agents; Dobutamine; Double-Blind Method; Female; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Natriuretic Peptide, Brain; Pyridazines; Simendan; Survival Analysis

2007
Levosimendan allows detection of contractile reserve in patients with chronic ischaemic left ventricular dysfunction and non-diagnostic dobutamine echocardiography.
    European journal of heart failure, 2007, Volume: 9, Issue:9

    Topics: Cardiotonic Agents; Dobutamine; Echocardiography; Humans; Hydrazones; Myocardial Contraction; Myocardial Ischemia; Pyridazines; Simendan; Ventricular Dysfunction, Left

2007
Effects of levosimendan versus dobutamine on long-term survival of patients with cardiogenic shock after primary coronary angioplasty.
    International journal of cardiology, 2008, Jul-04, Volume: 127, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Cardiotonic Agents; Dobutamine; Female; Humans; Hydrazones; Male; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Pyridazines; Shock, Cardiogenic; Simendan; Survival Rate; Treatment Outcome; Ventricular Dysfunction, Left

2008
Effects of levosimendan versus dobutamine on left ventricular diastolic function in patients with cardiogenic shock after primary angioplasty.
    International journal of cardiology, 2008, Aug-18, Volume: 128, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Cardiotonic Agents; Diastole; Dobutamine; Echocardiography, Doppler; Female; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Pyridazines; Shock, Cardiogenic; Simendan; Ventricular Function, Left

2008
Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shock.
    Critical care medicine, 2007, Volume: 35, Issue:12

    Topics: Angioplasty, Balloon, Coronary; Cardiotonic Agents; Catecholamines; Dobutamine; Female; Hemodynamics; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Pyridazines; Shock, Cardiogenic; Simendan

2007
Effect of levosimendan on right ventricular systolic and diastolic functions in patients with ischaemic heart failure.
    International journal of clinical practice, 2008, Volume: 62, Issue:2

    Topics: Aged; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Simendan; Treatment Outcome; Ventricular Function, Right

2008
Levosimendan improves renal function in patients with acute decompensated heart failure: comparison with dobutamine.
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:6

    Topics: Acute Disease; Aged; Cardiotonic Agents; Dobutamine; Female; Glomerular Filtration Rate; Heart Failure; Humans; Hydrazones; Kidney; Male; Middle Aged; Pyridazines; Simendan; Urination

2007
Strain rate analysis and levosimendan improve detection of myocardial viability by dobutamine echocardiography in patients with post-infarction left ventricular dysfunction: a pilot study.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2008, Volume: 21, Issue:9

    Topics: Aged; Dobutamine; Drug Synergism; Echocardiography; Elasticity Imaging Techniques; Female; Humans; Hydrazones; Image Enhancement; Male; Myocardial Infarction; Pyridazines; Reproducibility of Results; Sensitivity and Specificity; Simendan; Ventricular Dysfunction, Left

2008
[The calcium sensitizer levosimendan gives superior results to dobutamine in postoperative low cardiac output syndrome].
    Revista espanola de cardiologia, 2008, Volume: 61, Issue:5

    Topics: Cardiac Output, Low; Cardiotonic Agents; Dobutamine; Female; Humans; Hydrazones; Male; Middle Aged; Postoperative Complications; Prospective Studies; Pyridazines; Simendan

2008
Levosimendan versus dobutamine in heart failure patients treated chronically with carvedilol.
    Cardiovascular therapeutics, 2008,Fall, Volume: 26, Issue:3

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Cardiotonic Agents; Carvedilol; Dobutamine; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Propanolamines; Pyridazines; Simendan; Time Factors; Treatment Outcome

2008
Effects of levosimendan on left atrial functions in patients with ischemic heart failure.
    Clinical cardiology, 2008, Volume: 31, Issue:12

    Topics: Aged; Atrial Function, Left; Blood Pressure; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Myocardial Ischemia; Pyridazines; Simendan; Stroke Volume; Ventricular Function, Left; Ventricular Pressure

2008
Levosimendan vs. dobutamine: outcomes for acute heart failure patients on beta-blockers in SURVIVE.
    European journal of heart failure, 2009, Volume: 11, Issue:3

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Cardiotonic Agents; Cause of Death; Dobutamine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Pyridazines; Simendan; Stroke Volume; Survival Rate; Treatment Outcome

2009
Comparative effects of levosimendan and dobutamine on right ventricular function in patients with biventricular heart failure.
    Heart and vessels, 2009, Volume: 24, Issue:1

    Topics: Aged; Cardiotonic Agents; Diastole; Dobutamine; Dose-Response Relationship, Drug; Echocardiography; Female; Follow-Up Studies; Heart Failure; Heart Ventricles; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Pyridazines; Simendan; Stroke Volume; Systole; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Function, Right

2009
Comparison of ischemic side effects of levosimendan and dobutamine with integrated backscatter analysis.
    Clinical cardiology, 2009, Volume: 32, Issue:4

    Topics: Cardiotonic Agents; Dobutamine; Electrocardiography; Female; Humans; Hydrazones; Image Interpretation, Computer-Assisted; Injections, Intravenous; Male; Middle Aged; Myocardial Ischemia; Predictive Value of Tests; Pyridazines; Radiography; Simendan; Stroke Volume; Treatment Outcome; Ventricular Function, Left

2009
The costs of treating acute heart failure: an economic analysis of the SURVIVE trial.
    Journal of medical economics, 2008, Volume: 11, Issue:3

    Topics: Acute Disease; Aged; Aged, 80 and over; Cardiotonic Agents; Cost-Benefit Analysis; Dobutamine; Female; Health Expenditures; Heart Failure; Humans; Hydrazones; Length of Stay; Male; Middle Aged; Patient Admission; Pyridazines; Simendan

2008
Effects of levosimendan versus dobutamine on left atrial function in decompensated heart failure.
    The Canadian journal of cardiology, 2009, Volume: 25, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Atrial Function, Left; Cardiotonic Agents; Dobutamine; Dose-Response Relationship, Drug; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Pyridazines; Simendan; Single-Blind Method; Treatment Outcome; Young Adult

2009
Intravenous levosimendan vs. dobutamine in acute decompensated heart failure patients on beta-blockers.
    European journal of heart failure, 2010, Volume: 12, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Analysis of Variance; Antihypertensive Agents; Cardiotonic Agents; Confidence Intervals; Dobutamine; Double-Blind Method; Female; Heart Failure; Hemodynamics; Humans; Hydrazones; Male; Myocardial Perfusion Imaging; Natriuretic Peptide, Brain; Odds Ratio; Perfusion; Pulmonary Wedge Pressure; Pyridazines; Simendan; Vasodilator Agents

2010
[Efficacy and safety of intravenous levosimendan compared with dobutamine in decompensated heart failure].
    Zhonghua xin xue guan bing za zhi, 2010, Volume: 38, Issue:6

    Topics: Aged; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Injections, Intravenous; Male; Middle Aged; Pyridazines; Simendan; Treatment Outcome

2010
Acute effects of levosimendan and dobutamine on QRS duration in patients with heart failure.
    Arquivos brasileiros de cardiologia, 2010, Volume: 95, Issue:6

    Topics: Aged; Cardiotonic Agents; Chi-Square Distribution; Dobutamine; Female; Heart Conduction System; Heart Failure; Humans; Hydrazones; Male; Muscle Contraction; Pyridazines; Simendan; Statistics, Nonparametric

2010
[Levosimendan and dobutamine have a similar profile for potential risk for cardiac arrhythmias during 24-hour infusion in patients with acute decompensated heart failure].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2010, Volume: 38, Issue:5

    Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiotonic Agents; Dobutamine; Electrocardiography, Ambulatory; Female; Heart Failure; Heart Rate; Humans; Hydrazones; Infusions, Parenteral; Male; Middle Aged; Pyridazines; Risk Factors; Simendan; Tachycardia, Ventricular; Ventricular Premature Complexes

2010
Beneficial association of β-blocker therapy on recovery from severe acute heart failure treatment: data from the Survival of Patients With Acute Heart Failure in Need of Intravenous Inotropic Support trial.
    Critical care medicine, 2011, Volume: 39, Issue:5

    Topics: Acute Disease; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Cardiotonic Agents; Confidence Intervals; Dobutamine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Heart Failure; Hospital Mortality; Humans; Hydrazones; Infusions, Intravenous; International Cooperation; Kaplan-Meier Estimate; Male; Middle Aged; Patient Discharge; Proportional Hazards Models; Pyridazines; Reference Values; Risk Assessment; Severity of Illness Index; Simendan; Survival Analysis; Treatment Outcome

2011
The effects of levosimendan vs dobutamine added to dopamine on liver functions assessed with noninvasive liver function monitoring in patients with septic shock.
    Journal of critical care, 2012, Volume: 27, Issue:3

    Topics: Cardiotonic Agents; Coloring Agents; Dobutamine; Dopamine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hydrazones; Indocyanine Green; Liver Circulation; Liver Function Tests; Male; Metabolic Clearance Rate; Microcirculation; Middle Aged; Prospective Studies; Pyridazines; Regional Blood Flow; Shock, Septic; Simendan

2012
[The effect of levosimendan and dobutamine treatment on QT dispersion in patients with decompensated heart failure: a prospective study].
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2012, Volume: 12, Issue:1

    Topics: Aged; Arrhythmias, Cardiac; Cardiotonic Agents; Cohort Studies; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Male; Prospective Studies; Pyridazines; Simendan; Treatment Outcome

2012
[Hemodynamic and efficacies of domestic levosimendan versus dobutamine in patients with acute decompensated heart failure].
    Zhonghua yi xue za zhi, 2012, Feb-28, Volume: 92, Issue:8

    Topics: Adolescent; Adult; Dobutamine; Double-Blind Method; Female; Heart Failure; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Simendan; Treatment Outcome; Young Adult

2012
[Comparison on efficacy and safety between domestic levosimendan versus dobutamine for patients with acute decompensated heart failure].
    Zhonghua xin xue guan bing za zhi, 2012, Volume: 40, Issue:2

    Topics: Aged; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Pyridazines; Simendan; Treatment Outcome

2012
Levosimendan is superior to dobutamine as an inodilator in the treatment of pulmonary hypertension for children undergoing cardiac surgery.
    Journal of anesthesia, 2013, Volume: 27, Issue:3

    Topics: Blood Pressure; Cardiac Output; Cardiac Surgical Procedures; Cardiotonic Agents; Child, Preschool; Dobutamine; Female; Humans; Hydrazones; Hypertension, Pulmonary; Infant; Male; Prospective Studies; Pulmonary Artery; Pyridazines; Simendan

2013
A comparison of dobutamine and levosimendan on hepatic blood flow in patients with a low cardiac output state after cardiac surgery: a randomised controlled study.
    Anaesthesia and intensive care, 2013, Volume: 41, Issue:6

    Topics: Aged; Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Dobutamine; Female; Hemodynamics; Humans; Hydrazones; Liver Circulation; Male; Postoperative Complications; Pyridazines; Simendan; Vascular Resistance

2013
Assessment of sustained effects of levosimendan and dobutamine on left ventricular systolic functions by using novel tissue Doppler derived indices in patients with advanced heart failure.
    Cardiology journal, 2015, Volume: 22, Issue:1

    Topics: Aged; Biomarkers; Cardiotonic Agents; Dobutamine; Echocardiography, Doppler; Female; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Predictive Value of Tests; Pyridazines; Recovery of Function; Simendan; Stroke Volume; Systole; Time Factors; Treatment Outcome; Turkey; Ventricular Dysfunction, Left; Ventricular Function, Left

2015
Ischemia-modified albumin levels in patients with acute decompensated heart failure treated with dobutamine or levosimendan: IMA-HF study.
    Anatolian journal of cardiology, 2015, Volume: 15, Issue:8

    Topics: Adolescent; Adult; Aged; Biomarkers; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Pyridazines; Serum Albumin; Serum Albumin, Human; Simendan; Treatment Outcome; Turkey; Young Adult

2015
Effect of baseline characteristics on mortality in the SURVIVE trial on the effect of levosimendan vs dobutamine in acute heart failure: Sub-analysis of the Finnish patients.
    International journal of cardiology, 2016, Jul-15, Volume: 215

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Dobutamine; Drug Therapy, Combination; Female; Finland; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Proportional Hazards Models; Pyridazines; Retrospective Studies; Simendan; Survival Analysis; Treatment Outcome

2016
Levosimendan Versus Dobutamine in Myocardial Injury Patients with Septic Shock: A Randomized Controlled Trial.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, May-03, Volume: 22

    Topics: Biomarkers; Demography; Dobutamine; Fatty Acid-Binding Proteins; Female; Hemodynamics; Humans; Hydrazones; Lactic Acid; Male; Middle Aged; Multivariate Analysis; Myocardium; Natriuretic Peptide, Brain; Pyridazines; Regression Analysis; Shock, Septic; Simendan; Troponin I; Ventricular Function, Left

2016
Effects of Levosimendan on Cellular Metabolic Alterations in Patients With Septic Shock: A Randomized Controlled Pilot Study.
    Shock (Augusta, Ga.), 2017, Volume: 48, Issue:3

    Topics: Adult; Aged; Dobutamine; Double-Blind Method; Humans; Hydrazones; Male; Middle Aged; Pilot Projects; Pyridazines; Shock, Septic; Simendan

2017
Differential Effects of Levosimendan and Dobutamine on Glomerular Filtration Rate in Patients With Heart Failure and Renal Impairment:A Randomized Double-Blind Controlled Trial.
    Journal of the American Heart Association, 2018, 08-21, Volume: 7, Issue:16

    Topics: Aged; Cardio-Renal Syndrome; Cardiotonic Agents; Dobutamine; Double-Blind Method; Female; Glomerular Filtration Rate; Heart Failure; Hemodynamic Monitoring; Hemodynamics; Humans; Male; Middle Aged; p-Aminohippuric Acid; Renal Circulation; Renal Insufficiency; Renal Plasma Flow; Simendan

2018
Efficacy of Levosimendan in the Treatment of Patients With Severe Septic Cardiomyopathy.
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:3

    Topics: Cardiomyopathies; Cardiotonic Agents; Dobutamine; Humans; Hydrazones; Norepinephrine; Prospective Studies; Pyridazines; Sepsis; Shock, Septic; Simendan; Single-Blind Method; Stroke Volume; Ventricular Function, Left

2023

Other Studies

71 other study(ies) available for simendan and dobutamine

ArticleYear
Levosimendan: effects of a calcium sensitizer on function and arrhythmias and cyclic nucleotide levels during ischemia/reperfusion in the Langendorff-perfused guinea pig heart.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Agonists; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Dobutamine; Glyburide; Guinea Pigs; Heart; Hydrazones; In Vitro Techniques; L-Lactate Dehydrogenase; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nucleotides, Cyclic; Phosphocreatine; Pyridazines; Simendan; Stereoisomerism

1999
Preliminary clinical experience with the repetitive administration of levosimendan in patients with end-stage heart failure.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2003, Volume: 4 Suppl 2

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Pressure; Calcium Channels, L-Type; Cardiac Output, Low; Cardiotonic Agents; Diastole; Dobutamine; Dopamine; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Greece; Heart Failure; Heart Ventricles; Hematocrit; Hemoglobins; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Myocardial Contraction; Potassium; Pyridazines; Severity of Illness Index; Simendan; Stimulation, Chemical; Survival Analysis; Systole; Treatment Outcome; Ventricular Dysfunction, Left

2003
Comparision of the inotropic effects of levosimendan, rolipram, and dobutamine on human atrial trabeculae.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:5

    Topics: Adult; Aged; Cardiotonic Agents; Coronary Artery Disease; Dobutamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Female; Heart Atria; Heart Valve Diseases; Humans; Hydrazones; Male; Middle Aged; Myocardial Contraction; Pyridazines; Rheumatic Heart Disease; Rolipram; Simendan; Troponin C

2004
Levosimendan is superior to milrinone and dobutamine in selectively increasing microvascular gastric mucosal oxygenation in dogs.
    Critical care medicine, 2005, Volume: 33, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Dobutamine; Dogs; Female; Gastric Mucosa; Hemodynamics; Hydrazones; Male; Microcirculation; Milrinone; Oxygen; Pyridazines; Simendan; Treatment Outcome; Vasodilator Agents

2005
Levosimendan and gut mucosal blood flow--not all inotropes are created equal.
    Critical care medicine, 2005, Volume: 33, Issue:1

    Topics: Animals; Cardiotonic Agents; Dobutamine; Dogs; Gastric Mucosa; Hemoglobinometry; Hydrazones; Microcirculation; Milrinone; Oxygen Consumption; Pyridazines; Simendan; Vasodilator Agents

2005
Comparison between dobutamine and levosimendan for management of postresuscitation myocardial dysfunction.
    Critical care medicine, 2005, Volume: 33, Issue:3

    Topics: Analysis of Variance; Animals; Cardiomyopathies; Cardiopulmonary Resuscitation; Cardiotonic Agents; Dobutamine; Heart Arrest; Hydrazones; Male; Myocardial Stunning; Prospective Studies; Pyridazines; Random Allocation; Simendan; Swine

2005
Inotropic options for postresuscitation myocardial dysfunction.
    Critical care medicine, 2005, Volume: 33, Issue:3

    Topics: Animals; Cardiomyopathies; Cardiopulmonary Resuscitation; Cardiotonic Agents; Dobutamine; Heart Arrest; Humans; Hydrazones; Myocardial Stunning; Pyridazines; Simendan; Swine

2005
Efficacy and safety of intermittent, long-term, concomitant dobutamine and levosimendan infusions in severe heart failure refractory to dobutamine alone.
    The American journal of cardiology, 2005, Mar-15, Volume: 95, Issue:6

    Topics: Adult; Aged; Cardiotonic Agents; Chronic Disease; Dobutamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Multivariate Analysis; Pyridazines; Radionuclide Ventriculography; Risk; Simendan; Survival Rate

2005
[Cost analysis of the treatment of acute decompensated heart failure. Levosimendan versus dobutamine].
    Arquivos brasileiros de cardiologia, 2005, Volume: 85, Issue:1

    Topics: Acute Disease; Adrenergic beta-Agonists; Cardiotonic Agents; Cost-Benefit Analysis; Dobutamine; Health Care Costs; Heart Failure; Hospital Costs; Humans; Hydrazones; Length of Stay; Pyridazines; Simendan

2005
Levosimendan improves postresuscitation outcomes in a rat model of CPR.
    The Journal of laboratory and clinical medicine, 2005, Volume: 146, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Cardiac Output; Cardiopulmonary Resuscitation; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Heart Arrest; Heart Rate; Hydrazones; Male; Pyridazines; Random Allocation; Rats; Rats, Sprague-Dawley; Simendan; Single-Blind Method; Survival Rate; Ventricular Fibrillation; Ventricular Function, Left

2005
Ischemia-reperfusion injury changes the dynamics of Ca2+-contraction coupling due to inotropic drugs in isolated hearts.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 100, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Digoxin; Dobutamine; Dopamine; Dopamine Agonists; Feedback, Physiological; Guinea Pigs; Heart; Hydrazones; In Vitro Techniques; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Pyridazines; Signal Transduction; Simendan; Ventricular Function, Left

2006
[On levosimendan in comparison with dobutamine].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:2

    Topics: Cardiotonic Agents; Dobutamine; Humans; Hydrazones; Pyridazines; Simendan

2006
[Therapy of acute decompensated heart failure with levosimendan].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Mar-22, Volume: 101 Suppl 1

    Topics: Adult; Aged; Calcium Channel Agonists; Cardiotonic Agents; Conscious Sedation; Critical Care; Dobutamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Heart Failure; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Norepinephrine; Pyridazines; Shock, Cardiogenic; Simendan

2006
Effects of levosimendan versus dobutamine on pressure load-induced right ventricular failure.
    Critical care medicine, 2006, Volume: 34, Issue:11

    Topics: Animals; Cardiotonic Agents; Dobutamine; Dogs; Heart Failure; Hydrazones; Hypertension, Pulmonary; Prospective Studies; Pulmonary Artery; Pulmonary Circulation; Pyridazines; Random Allocation; Simendan; Ventricular Dysfunction, Right

2006
Effects of levosimendan and dobutamine in experimental acute endotoxemia: a preliminary controlled study.
    Intensive care medicine, 2007, Volume: 33, Issue:3

    Topics: Acidosis; Analysis of Variance; Animals; Cardiotonic Agents; Dobutamine; Endotoxemia; Hydrazones; Lactic Acid; Oxygen; Prospective Studies; Pyridazines; Random Allocation; Sheep; Shock, Septic; Simendan; Splanchnic Circulation

2007
Levosimendan in cardiac surgery: a unique drug for the treatment of perioperative left ventricular dysfunction or just another inodilator searching for a clinical application?
    Anesthesia and analgesia, 2007, Volume: 104, Issue:4

    Topics: Adrenergic beta-Agonists; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; Dobutamine; Drug Therapy, Combination; Humans; Hydrazones; Milrinone; Myocardial Contraction; Perioperative Care; Phosphodiesterase Inhibitors; Pyridazines; Simendan; Stroke Volume; Vasodilator Agents; Ventricular Dysfunction, Left

2007
Levosimendan restores both systolic and diastolic cardiac performance in lipopolysaccharide-treated rabbits: comparison with dobutamine and milrinone.
    Critical care medicine, 2007, Volume: 35, Issue:5

    Topics: Animals; Cardiotonic Agents; Diastole; Disease Models, Animal; Dobutamine; Heart Failure; Hydrazones; Lipopolysaccharides; Milrinone; Pyridazines; Rabbits; Sepsis; Simendan; Systole; Ventricular Function, Left

2007
A struggle to SURVIVE: to abandon or not to abandon levosimendan?
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:5

    Topics: Acute Disease; Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Hydrazones; Natriuretic Peptide, Brain; Pyridazines; Simendan; Survival Rate; Treatment Outcome

2007
Both levosimendan and dobutamine treatments result in significant reduction of NT-proBNP levels, but levosimendan has better and prolonged neurohormonal effects than dobutamine.
    International journal of cardiology, 2008, Jul-21, Volume: 127, Issue:3

    Topics: Dobutamine; Humans; Hydrazones; Natriuretic Peptide, Brain; Neurotransmitter Agents; Peptide Fragments; Protein Precursors; Pyridazines; Simendan; Treatment Outcome

2008
Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1

    Topics: Acetamides; Animals; Blood Pressure; Calcium; Cardiac Output; Cardiotonic Agents; Cardiovascular System; Dobutamine; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hydrazones; Male; Milrinone; Myocardial Contraction; Oxygen Consumption; Potassium; Potassium Channels; Pulmonary Circulation; Pyridazines; Simendan; Time Factors; Vascular Resistance; Vasodilator Agents; Ventricular Function, Left

2008
Levosimendan improves renal function in acute decompensated heart failure: cause and clinical application. Editorial to: "Levosimendan improves renal function in patients with acute decompensated heart failure: comparison with dobutamine by Yilmaz et al."
    Cardiovascular drugs and therapy, 2007, Volume: 21, Issue:6

    Topics: Acute Disease; Cardiotonic Agents; Dobutamine; Glomerular Filtration Rate; Heart Failure; Humans; Hydrazones; Kidney; Pyridazines; Simendan

2007
Evoked changes in cardiovascular function in rats by infusion of levosimendan, OR-1896 [(R)-N-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)acetamide], OR-1855 [(R)-6-(4-aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one], dobutamine, and m
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Cardiovascular Physiological Phenomena; Dobutamine; Drug Combinations; Heart Rate; Hemodynamics; Hydrazones; Male; Milrinone; Myocardial Contraction; Pyridazines; Rats; Rats, Sprague-Dawley; Simendan; Vascular Resistance

2008
Natriuretic peptide-guided levosimendan therapy for heart failure: a promising new approach.
    International journal of cardiology, 2008, Aug-01, Volume: 128, Issue:1

    Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Natriuretic Peptide, Brain; Predictive Value of Tests; Prognosis; Pyridazines; Simendan; Time Factors

2008
The prolonged lowering effect of levosimendan on brain natriuretic peptide levels in patients with decompansated heart failure: clinical implications.
    International journal of cardiology, 2008, Aug-01, Volume: 128, Issue:1

    Topics: Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Natriuretic Peptide, Brain; Predictive Value of Tests; Prognosis; Pyridazines; Simendan; Time Factors

2008
Inotropic agents improve the peripheral microcirculation of patients with end-stage chronic heart failure.
    Journal of cardiac failure, 2008, Volume: 14, Issue:5

    Topics: Adrenergic beta-Agonists; Brachial Artery; Cardiotonic Agents; Case-Control Studies; Chronic Disease; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Male; Microcirculation; Middle Aged; Muscle, Skeletal; Myocardial Reperfusion; Oxygen Consumption; Prognosis; Prospective Studies; Pyridazines; Simendan; Spectroscopy, Near-Infrared; Vasodilator Agents

2008
Usefulness of dobutamine-induced changes of the two-dimensional longitudinal deformation predict clinical and neurohumoral improvement in men after levosimendan treatment in acutely decompensated chronic heart failure.
    The American journal of cardiology, 2008, Nov-01, Volume: 102, Issue:9

    Topics: Aged; Cardiotonic Agents; Dobutamine; Echocardiography, Stress; Female; Heart Failure; Heart Ventricles; Humans; Hydrazones; Male; Middle Aged; Natriuretic Peptide, Brain; Pyridazines; Severity of Illness Index; Simendan; Stroke Volume

2008
[Superiority of levosimendan to dobutamine in postoperative low cardiac output syndrome: is it due to previous beta-blocker treatment?].
    Revista espanola de cardiologia, 2008, Volume: 61, Issue:11

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cardiac Output, Low; Dobutamine; Drug Interactions; Humans; Hydrazones; Length of Stay; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Vasodilator Agents

2008
Effects of levosimendan and dobutamine on experimental acute lung injury in rats.
    Acta histochemica, 2009, Volume: 111, Issue:5

    Topics: Acute Lung Injury; Animals; Cardiotonic Agents; Dobutamine; Hydrazones; Hypertension; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-1beta; Lung; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyridazines; Rats; Rats, Wistar; Simendan; Tumor Necrosis Factor-alpha

2009
Levosimendan: from basic science to clinical practice.
    Heart failure reviews, 2009, Volume: 14, Issue:4

    Topics: Animals; Cardiotonic Agents; Coronary Circulation; Dobutamine; Heart Failure; Hemodynamics; Humans; Hydrazones; Kidney; Myocardial Contraction; Natriuretic Peptide, Brain; Prognosis; Pyridazines; Quality of Life; Simendan; Vasodilator Agents; Ventricular Dysfunction, Left; Ventricular Function, Right

2009
Intermittent inotropic infusions combined with prophylactic oral amiodarone for patients with decompensated end-stage heart failure.
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:2

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Cardiotonic Agents; Chronic Disease; Dobutamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Pyridazines; Simendan; Survival Rate; Treatment Outcome

2009
Anti-ischemic effects of inotropic agents in experimental right ventricular infarction.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:7

    Topics: Animals; Blood Gas Analysis; Cardiotonic Agents; Dobutamine; Female; Heart Ventricles; Hemodynamics; Hydrazones; Inflammation Mediators; Milrinone; Myocardial Infarction; Myocardial Ischemia; Myocarditis; Myocardium; Myoglobin; Neutrophil Infiltration; Pyridazines; Simendan; Swine; Troponin T

2009
Lowered B-type natriuretic peptide in response to levosimendan or dobutamine treatment is associated with improved survival in patients with severe acutely decompensated heart failure.
    Journal of the American College of Cardiology, 2009, Jun-23, Volume: 53, Issue:25

    Topics: Aged; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Natriuretic Peptide, Brain; Pyridazines; Randomized Controlled Trials as Topic; Retrospective Studies; Simendan

2009
Levosimendan vs dobutamine in septic shock.
    Journal of critical care, 2009, Volume: 24, Issue:3

    Topics: APACHE; Cardiotonic Agents; Dobutamine; Humans; Hydrazones; Lactic Acid; Pyridazines; Randomized Controlled Trials as Topic; Shock, Septic; Simendan

2009
Influence of temperature on the positive inotropic effect of levosimendan, dobutamine and milrinone.
    European journal of anaesthesiology, 2009, Volume: 26, Issue:11

    Topics: Animals; Calcium; Cardiotonic Agents; Dobutamine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hydrazones; Hypothermia; In Vitro Techniques; Milrinone; Myocardial Contraction; Pyridazines; Random Allocation; Simendan; Temperature

2009
Inotropic support during experimental endotoxemic shock: part II. A comparison of levosimendan with dobutamine.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Animals; Blood Pressure; Blood Volume; Cardiac Output; Cardiotonic Agents; Combined Modality Therapy; Disease Models, Animal; Dobutamine; Drug Therapy, Combination; Fluid Therapy; Heart Rate; Hemodynamics; Hydrazones; Hypotension; Lactic Acid; Lipopolysaccharides; Liver Circulation; Norepinephrine; Oxygen; Pyridazines; Regional Blood Flow; Shock, Septic; Simendan; Splanchnic Circulation; Swine; Time Factors; Vascular Resistance

2009
Levosimendan as a rescue drug in experimental propranolol-induced myocardial depression: a randomized study.
    Annals of emergency medicine, 2009, Volume: 54, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Dobutamine; Double-Blind Method; Drug Overdose; Heart Failure; Hemodynamics; Hydrazones; Propranolol; Pyridazines; Random Allocation; Simendan; Survival Analysis; Swine

2009
Levosimendan in acute and chronic right ventricle failure.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:1

    Topics: Adrenergic beta-Agonists; Cardiotonic Agents; Dobutamine; Hemodynamics; Humans; Hydrazones; Pyridazines; Simendan; Ventricular Dysfunction, Right

2010
Direct cardiac effects of dobutamine, dopamine, epinephrine, and levosimendan in isolated septic rat hearts.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:3

    Topics: Animals; Cardiotonic Agents; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Heart; Heart Rate; Hydrazones; In Vitro Techniques; Male; Models, Animal; Myocardium; Oxygen Consumption; Peritonitis; Pyridazines; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Simendan; Therapeutic Equivalency

2010
Oxygen-wasting effect of inotropy: is there a need for a new evaluation? An experimental large-animal study using dobutamine and levosimendan.
    Circulation. Heart failure, 2010, Volume: 3, Issue:2

    Topics: Analysis of Variance; Animals; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Hydrazones; Male; Myocardial Contraction; Myocardial Stunning; Oxygen Consumption; Pyridazines; Simendan; Swine

2010
Superiority of levosimendan over dobutamine in right ventricle failure.
    Critical care medicine, 2010, Volume: 38, Issue:1

    Topics: Cardiotonic Agents; Critical Care; Critical Illness; Dobutamine; Female; Heart Function Tests; Humans; Hydrazones; Hypertension, Pulmonary; Intensive Care Units; Male; Myocardial Infarction; Prognosis; Pyridazines; Shock, Cardiogenic; Simendan; Survival Rate; Treatment Outcome; Vascular Resistance; Ventricular Dysfunction, Right

2010
Is levosimendan better than dobutamine in acute heart failure in patients on beta-blockade treatment? What is the evidence?
    European journal of heart failure, 2010, Volume: 12, Issue:4

    Topics: Acute Disease; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cardiotonic Agents; Dobutamine; Drug Therapy, Combination; Evidence-Based Medicine; Heart Failure; Humans; Hydrazones; Pyridazines; Simendan

2010
Weaning difficult-to-wean chronic obstructive pulmonary disease patients: a pilot study comparing initial hemodynamic effects of levosimendan and dobutamine.
    Journal of critical care, 2011, Volume: 26, Issue:1

    Topics: Aged; Aged, 80 and over; Cardiotonic Agents; Dobutamine; Female; Hemodynamics; Humans; Hydrazones; Male; Middle Aged; Pilot Projects; Prospective Studies; Pulmonary Disease, Chronic Obstructive; Pulmonary Wedge Pressure; Pyridazines; Respiration; Respiration, Artificial; Simendan; Ventilator Weaning; Ventricular Dysfunction, Left

2011
Rotating inotrope therapy in a pediatric population with decompensated heart failure.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2011, Volume: 12, Issue:1

    Topics: Adolescent; Cardiotonic Agents; Dobutamine; Drug Therapy, Combination; Echocardiography; Female; Heart Failure; Humans; Hydrazones; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Male; Milrinone; Pyridazines; Retrospective Studies; Simendan; Treatment Outcome

2011
Acute heart failure with low cardiac output: can we develop a short-term inotropic agent that does not increase adverse events?
    Current heart failure reports, 2010, Volume: 7, Issue:3

    Topics: Acute Disease; Animals; Cardiac Output; Cardiotonic Agents; Clinical Trials as Topic; Digoxin; Dobutamine; Etiocholanolone; Genetic Therapy; Heart Failure; Humans; Hydrazones; Pyridazines; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Simendan; Sodium-Potassium-Exchanging ATPase; Urea

2010
Correspondence concerning the article: is levosimendan better than dobutamine in acute heart failure in patients on beta blockade treatment? What is the evidence?
    European journal of heart failure, 2010, Volume: 12, Issue:8

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Hydrazones; Pyridazines; Simendan

2010
How to treat acute decompensated heart failure in the 'beta-blocker era'?
    European journal of heart failure, 2010, Volume: 12, Issue:8

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Hydrazones; Pyridazines; Simendan; Vasodilator Agents

2010
Dobutamine-induced changes of left atrial two-dimensional deformation predict clinical and neurohumoral improvement after levosimendan treatment in patients with acutely decompensated chronic heart failure.
    International journal of cardiology, 2012, May-17, Volume: 157, Issue:1

    Topics: Aged; Atrial Function, Left; Biomarkers; Chronic Disease; Dobutamine; Echocardiography; Echocardiography, Stress; Female; Forecasting; Heart Failure; Humans; Hydrazones; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Pyridazines; Simendan; Treatment Outcome

2012
[Treatment of heart failure patients with inotropic drugs: beyond traditional agents].
    Giornale italiano di cardiologia (2006), 2010, Volume: 11, Issue:10 Suppl 1

    Topics: Adrenergic beta-1 Receptor Agonists; Cardiotonic Agents; Dobutamine; Guidelines as Topic; Heart Failure; Hydrazones; Meta-Analysis as Topic; Phosphodiesterase Inhibitors; Pyridazines; Retrospective Studies; Risk Assessment; Simendan

2010
Cost-effectiveness of levosimendan in patients with acute heart failure.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:4

    Topics: Acute Disease; Aged; Cardiotonic Agents; Cost-Benefit Analysis; Dobutamine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Failure; Humans; Hydrazones; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Patient Readmission; Pyridazines; Retrospective Studies; Simendan; Survival Rate

2011
Prevention for pediatric low cardiac output syndrome: results from the European survey EuLoCOS-Paed.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:12

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiotonic Agents; Child, Preschool; Dobutamine; Dopamine; Drug Therapy, Combination; Epinephrine; Europe; Health Care Surveys; Hospitals; Humans; Hydrazones; Infant; Milrinone; Pediatrics; Practice Patterns, Physicians'; Pyridazines; Simendan; Surveys and Questionnaires

2011
[Levosimendan treatment of severe acute congestive heart failure refractory to dobutamine/milrinone in children].
    Vojnosanitetski pregled, 2011, Volume: 68, Issue:11

    Topics: Acute Disease; Adolescent; Cardiotonic Agents; Child, Preschool; Dobutamine; Heart Failure; Humans; Hydrazones; Male; Milrinone; Pyridazines; Simendan

2011
Pharmacologic interventions to improve splanchnic oxygenation during ventilation with positive end-expiratory pressure.
    Advances in experimental medicine and biology, 2012, Volume: 737

    Topics: Anesthesia, Epidural; Dobutamine; Dopamine; Humans; Hydrazones; Milrinone; Oxygen; Oxygen Consumption; Oxyhemoglobins; Positive-Pressure Respiration; Pulmonary Ventilation; Pyridazines; Receptors, Catecholamine; Simendan; Splanchnic Circulation; Vital Capacity

2012
Liver function abnormalities, clinical profile, and outcome in acute decompensated heart failure.
    European heart journal, 2013, Volume: 34, Issue:10

    Topics: Acute Disease; Aged; Alkaline Phosphatase; Cardiotonic Agents; Cholestasis; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Liver Diseases; Liver Function Tests; Male; Prognosis; Prospective Studies; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Transaminases

2013
Economic evaluation of levosimendan versus dobutamine for the treatment of acute heart failure in Italy.
    Advances in therapy, 2012, Volume: 29, Issue:12

    Topics: Cardiotonic Agents; Cost-Benefit Analysis; Dobutamine; Heart Failure; Hospitalization; Humans; Hydrazones; Pyridazines; Retrospective Studies; Rome; Simendan; Treatment Outcome

2012
Levosimendan: a retrospective single-center case series.
    Journal of critical care, 2013, Volume: 28, Issue:6

    Topics: Aged; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Hemodynamics; Hospital Mortality; Humans; Hydrazones; Intensive Care Units; Male; Milrinone; Norepinephrine; Pyridazines; Retrospective Studies; Simendan; Sympathomimetics; Treatment Outcome

2013
Chronic measurement of left ventricular pressure in freely moving rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Volume: 115, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Calcium Channel Blockers; Dobutamine; Heart Rate; Hydrazones; Isoproterenol; Male; Pyridazines; Rats; Rats, Wistar; Simendan; Telemetry; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure; Verapamil

2013
Utility of the neutrophil to lymphocyte ratio for predicting in-hospital mortality after levosimendan infusion in patients with acute decompensated heart failure.
    Journal of cardiology, 2014, Volume: 63, Issue:6

    Topics: Acute Disease; Aged; Cardiotonic Agents; Disease Progression; Dobutamine; Female; Heart Failure; Hospital Mortality; Humans; Hydrazones; Infusions, Intravenous; Leukocyte Count; Lymphocyte Count; Male; Middle Aged; Neutrophils; Predictive Value of Tests; Pyridazines; Retrospective Studies; Simendan

2014
[Nitrid oxide, levosimendan and sildenafile in a patient with right ventricle dysfunction and severe pulmonary hypertension after cardiac surgery].
    Revista espanola de anestesiologia y reanimacion, 2014, Volume: 61, Issue:9

    Topics: Aged; Aorta; Dobutamine; Drug Synergism; Drug Therapy, Combination; Female; Heart Valve Prosthesis Implantation; Humans; Hydrazones; Hypertension, Pulmonary; Nitric Oxide; Norepinephrine; Postoperative Complications; Pyridazines; Sildenafil Citrate; Simendan; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Right

2014
Cost-benefits of incorporating levosimendan into cardiac surgery practice: German base case.
    Journal of medical economics, 2016, Volume: 19, Issue:5

    Topics: Cardiac Surgical Procedures; Cardiotonic Agents; Cost-Benefit Analysis; Dobutamine; Germany; Humans; Hydrazones; Insurance, Health; Length of Stay; Markov Chains; Models, Econometric; Pyridazines; Simendan

2016
Dose-Response Head-to-Head Comparison of Inodilators Dobutamine, Milrinone, and Levosimendan in Chronic Experimental Pulmonary Hypertension.
    Journal of cardiovascular pharmacology and therapeutics, 2017, Volume: 22, Issue:5

    Topics: Animals; Calcium; Chronic Disease; Dobutamine; Dose-Response Relationship, Drug; Hemodynamics; Hydrazones; Hypertension, Pulmonary; Male; Milrinone; Pyridazines; Rats; Rats, Wistar; Simendan

2017
Inotropes and cardiorenal syndrome in acute heart failure - A retrospective comparative analysis.
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2017, Volume: 36, Issue:9

    Topics: Acute Disease; Aged; Cardio-Renal Syndrome; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Humans; Hydrazones; Incidence; Male; Middle Aged; Pyridazines; Retrospective Studies; Simendan

2017
Ambulatory Intravenous Inotropic Support and or Levosimendan in Pediatric and Congenital Heart Failure: Safety, Survival, Improvement, or Transplantation.
    Pediatric cardiology, 2018, Volume: 39, Issue:7

    Topics: Adolescent; Adult; Cardiotonic Agents; Child; Child, Preschool; Dobutamine; Female; Follow-Up Studies; Heart Failure; Heart Transplantation; Humans; Infant; Infusions, Intravenous; Male; Milrinone; Retrospective Studies; Simendan; Survival Rate; Treatment Outcome; Young Adult

2018
Treatments targeting inotropy.
    European heart journal, 2019, 11-21, Volume: 40, Issue:44

    Topics: Acute Disease; Animals; Antioxidants; Calcium; Cardiotonic Agents; Case-Control Studies; Catecholamines; Clinical Trials as Topic; Diastole; Dobutamine; Dogs; Energy Metabolism; Excitation Contraction Coupling; Heart Failure; Humans; Mitochondria; Models, Animal; Myocardial Contraction; Nitrogen Oxides; Oxidation-Reduction; Phosphodiesterase Inhibitors; Placebos; Receptors, Adrenergic; Sarcomeres; Shock, Cardiogenic; Simendan; Swine; Systole; Urea

2019
Reversing Cholinergic Bronchoconstriction by Common Inotropic Agents: A Randomized Experimental Trial on Isolated Perfused Rat Lungs.
    Anesthesia and analgesia, 2019, Volume: 129, Issue:3

    Topics: Acetylcholine; Airway Resistance; Animals; Bronchoconstriction; Bronchodilator Agents; Cardiotonic Agents; Cholinergic Agents; Dobutamine; Lung; Male; Organ Culture Techniques; Random Allocation; Rats; Rats, Sprague-Dawley; Simendan

2019
Levosimendan with other inotropes or vasopressors: Should you combine them?
    The American journal of emergency medicine, 2020, Volume: 38, Issue:12

    Topics: Acute Disease; Aged; Aged, 80 and over; Arterial Pressure; Cardiotonic Agents; Dobutamine; Dopamine; Drug Therapy, Combination; Female; Heart Failure; Heart Rate; Hospital Mortality; Humans; Hypotension; Length of Stay; Male; Middle Aged; Norepinephrine; Simendan; Tachycardia, Supraventricular; Treatment Outcome; Vasoconstrictor Agents

2020
COVID-19 infection in left ventricular assist device patients.
    Journal of cardiac surgery, 2020, Volume: 35, Issue:11

    Topics: Aged; Cardiotonic Agents; COVID-19; Dobutamine; Furosemide; Heart Failure; Heart-Assist Devices; Humans; Male; Middle Aged; Simendan; Ventricular Dysfunction, Right

2020
Levosimendan or dobutamine in patients with low cardiac output syndrome: Results from meta-analysis.
    International journal of cardiology, 2021, 06-15, Volume: 333

    Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Dobutamine; Humans; Hydrazones; Pyridazines; Simendan

2021
Reply to: Levosimendan or dobutamine in patients with low cardiac output syndrome: Results from meta-analysis.
    International journal of cardiology, 2021, 08-01, Volume: 336

    Topics: Cardiac Output, Low; Dobutamine; Humans; Hydrazones; Pyridazines; Simendan

2021
Comparison of dobutamine and levosimendan for treatment of sepsis-induced cardiac dysfunction: A protocol for systematic review and meta-analysis.
    Medicine, 2022, Mar-18, Volume: 101, Issue:11

    Topics: Dobutamine; Heart Diseases; Humans; Meta-Analysis as Topic; Sepsis; Simendan; Systematic Reviews as Topic

2022
[Comparative assessment of the effects of dobutamine and levosimendan on right ventricular ejection fraction in patients with biventricular heart failure].
    Kardiologiia, 2023, Feb-28, Volume: 63, Issue:2

    Topics: Cardiovascular Agents; Cross-Sectional Studies; Dobutamine; Heart Failure; Humans; Prospective Studies; Simendan; Stroke Volume; Ventricular Function, Left; Ventricular Function, Right

2023
Preoperative Levosimendan Administration in Heart Transplant Patients with Severe Hepatic and Renal Impairment: A Retrospective Study.
    The heart surgery forum, 2023, Aug-14, Volume: 26, Issue:4

    Topics: Dobutamine; Dopamine; Heart Failure; Heart Transplantation; Humans; Renal Insufficiency; Retrospective Studies; Simendan

2023