Compounds > silybin
Page last updated: 2024-08-23

silybin and warfarin

silybin has been researched along with warfarin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Brantley, SJ; Kroll, DJ; Oberlies, NH; Paine, MF1
Beijnen, JH; Goey, AK; Huijbregts, TJ; Maas-Bakker, RF; Meijerman, I; Mooiman, KD; Schellens, JH1
Bálint, M; Bencsik, T; Boda, G; Hetényi, C; Kuzma, M; Mohos, V; Poór, M1

Other Studies

4 other study(ies) available for silybin and warfarin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:3

    Topics: Anticoagulants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Herb-Drug Interactions; Humans; Hydroxylation; In Vitro Techniques; Microsomes, Liver; Recombinant Proteins; Silybin; Silybum marianum; Silymarin; Stereoisomerism; Warfarin

2010
The in-vitro effect of complementary and alternative medicines on cytochrome P450 2C9 activity.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:9

    Topics: Aryl Hydrocarbon Hydroxylases; Camellia sinensis; Complementary Therapies; Coumarins; Herb-Drug Interactions; Humans; Microsomes, Liver; Plant Extracts; Silybin; Silybum marianum; Silymarin; Tolbutamide

2014
Pharmacokinetic interaction of diosmetin and silibinin with other drugs: Inhibition of CYP2C9-mediated biotransformation and displacement from serum albumin.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: Anisotropy; Biotransformation; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Diclofenac; Drug Interactions; Flavonoids; Humans; Kinetics; Molecular Docking Simulation; Serum Albumin; Serum Albumin, Bovine; Silybin; Silymarin; Spectrometry, Fluorescence; Time Factors; Ultrafiltration; Warfarin

2018