silybin has been researched along with tolbutamide in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Beijnen, JH; Goey, AK; Huijbregts, TJ; Maas-Bakker, RF; Meijerman, I; Mooiman, KD; Schellens, JH | 1 |
| Bernstein, HJ; Brinda, BJ; Chavin, KD; Frye, RF; Kawaguchi-Suzuki, M; Markowitz, JS; Zhu, HJ | 1 |
| Gurley, BJ; Markowitz, JS; Munoz, J; Wang, X; Zhu, HJ | 1 |
1 trial(s) available for silybin and tolbutamide
| Article | Year |
|---|---|
The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity.
Topics: Caffeine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dietary Supplements; Female; Herb-Drug Interactions; Humans; Male; Midazolam; Plant Extracts; Silybin; Silybum marianum; Silymarin; Tolbutamide; Young Adult | 2014 |
3 other study(ies) available for silybin and tolbutamide
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The in-vitro effect of complementary and alternative medicines on cytochrome P450 2C9 activity.
Topics: Aryl Hydrocarbon Hydroxylases; Camellia sinensis; Complementary Therapies; Coumarins; Herb-Drug Interactions; Humans; Microsomes, Liver; Plant Extracts; Silybin; Silybum marianum; Silymarin; Tolbutamide | 2014 |
An ex vivo approach to botanical-drug interactions: a proof of concept study.
Topics: Adult; Benzylisoquinolines; Berberine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Female; Herb-Drug Interactions; Humans; Hydrastis; Male; Microsomes, Liver; Midazolam; Plant Extracts; Silybin; Silybum marianum; Silymarin; Tolbutamide; Young Adult | 2015 |