silybin has been researched along with silychristin in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (25.81) | 29.6817 |
| 2010's | 20 (64.52) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Baiseitova, A; Ban, YJ; Jenis, J; Kim, JY; Li, ZP; Park, KH | 1 |
| Matsuda, H; Nakamura, S; Nakashima, S; Oda, Y; Xu, F; Yoshikawa, M | 1 |
| Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V | 1 |
| Anzenbacher, P; Dvorák, Z; Modrianský, M; Rohovský, P; Simánek, V; Ulrichová, J; Zuber, R | 1 |
| Barreto, JF; Carrier, DJ; Clausen, EC; Wallace, SN | 1 |
| Carrier, DJ; Clausen, EC; Duan, L | 1 |
| Barrett, JS; Hsu, BH; Lee, JI; Wu, D | 1 |
| Barrett, JS; Lee, JI; Narayan, M | 1 |
| Chen, J; Lu, C; Lu, Y; Wu, W; Zhang, W | 1 |
| Agarwal, R; Deep, G; Kroll, DJ; Oberlies, NH | 1 |
| Hasanloo, T; Kazemi Tabar, SK; Khalili, M; Rahnama, H | 1 |
| Chang, CH; Fang, JY; Hung, CF; Lin, YK; Zhang, LW | 1 |
| Abenavoli, L; Capasso, F; Capasso, R; Milic, N | 1 |
| Bernstein, HJ; Brinda, BJ; Chavin, KD; Markowitz, JS; Patrick, KS; Zhu, HJ | 1 |
| Ansari Jovini, M; Chaichi, MR; Hashemi, M; Jahanzad, E; Keshavarz Afshar, R | 1 |
| Barba, FJ; Barth, D; Ben Rahal, N; Chevalot, I | 1 |
| Biedermann, D; Biler, M; Křen, V; Kubala, M; Kuzma, M; Mojović, M; Popović-Bijelić, A; Pyszková, M; Sokolová, R; Trouillas, P; Ulrichová, J; Vacek, J; Valentová, K; Vrba, J | 1 |
| Petersen, M; Poppe, L | 1 |
| Fibigr, J; Šatínský, D; Solich, P | 1 |
| Bartůněk, P; Bednárová, L; Biedermann, D; Buchta, M; Cvačka, J; Holečková, V; Křen, V; Křenková, A; Kuzma, M; Peikerová, Ž; Sedlák, D; Škuta, C; Valentová, K | 1 |
| AbouZid, SF; Ahmed, HS; Brent Friesen, J; Chen, SN; McAlpine, JB; Moawad, AS; Nachtergael, A; Owis, AI; Pauli, GF | 1 |
| Biedermann, D; Dinkova-Kostova, AT; Křen, V; Roubalová, L; Ulrichová, J; Vrba, J | 1 |
| Bijak, M; Saluk-Bijak, J | 1 |
| Bijak, M; Dziedzic, A; Saluk-Bijak, J | 1 |
| Bijak, M; Dziedzic, A; Saluk-Bijak, J; Sliwinski, T; Synowiec, E | 1 |
| Bijak, M; Saluk-Bijak, J; Sitarek, P; Sliwiński, T; Synowiec, E | 1 |
| Bijak, M; Dziedzic, A; Saluk-Bijak, J; Szelenberger, R | 1 |
| Benada, O; Biedermann, D; Hrčková, G; Kofroňová, O; Kubašková, TM; Tumová, L | 1 |
| Abd El Mageed, AMA; AbouZid, SF; Ahmed, HS; Chen, SN; Friesen, JB; McAlpine, JB; Moawad, AS; Nachtergael, A; Owis, AI; Pauli, GF | 1 |
| Chen, Y; Li, H; Mao, X; Peng, Y; Wang, X; Yu, J; Zheng, J | 1 |
| Kosina, P; Křen, V; Lněničková, K; Papoušková, B; Ulrichová, J; Vrba, J | 1 |
1 review(s) available for silybin and silychristin
| Article | Year |
|---|---|
Milk thistle in liver diseases: past, present, future.
Topics: Animals; Antioxidants; Clinical Trials as Topic; Humans; Lipid Peroxidation; Liver Diseases; Molecular Structure; Phytotherapy; Silybin; Silybum marianum; Silymarin | 2010 |
30 other study(ies) available for silybin and silychristin
| Article | Year |
|---|---|
Tyrosinase inhibitory study of flavonolignans from the seeds of Silybum marianum (Milk thistle).
Topics: Chromatography, High Pressure Liquid; Flavonoids; Kinetics; Monophenol Monooxygenase; Oxidation-Reduction; Plant Extracts; Seeds; Silybum marianum; Silymarin; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Tyrosine | 2019 |
Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.
Topics: Agaricales; Animals; Antineoplastic Agents; Brassicaceae; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Intramolecular Oxidoreductases; Melanoma, Experimental; Membrane Glycoproteins; Mice; Monophenol Monooxygenase; Oxidoreductases; Plant Extracts; RNA, Messenger; Structure-Activity Relationship; Tumor Cells, Cultured | 2010 |
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins | 2020 |
Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities.
Topics: Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Flavonoids; Humans; Inhibitory Concentration 50; Isomerism; Liver; Microsomes, Liver; Phytotherapy; Plant Extracts; Silybin; Silybum marianum; Silymarin | 2002 |
Extraction of nutraceuticals from milk thistle: I. Hot water extraction.
Topics: Flour; Hot Temperature; Kinetics; Nutritive Value; Seeds; Silybin; Silybum marianum; Silymarin; Water | 2003 |
Silymarin extraction from milk thistle using hot water.
Topics: Biotechnology; Flavonols; Hot Temperature; Kinetics; Models, Chemical; Quercetin; Silybin; Silybum marianum; Silymarin; Solvents; Temperature; Time Factors; Water | 2004 |
Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Plant Extracts; Silybin; Silybum marianum; Silymarin; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2006 |
Analysis and comparison of active constituents in commercial standardized silymarin extracts by liquid chromatography-electrospray ionization mass spectrometry.
Topics: Chromatography, Liquid; Plant Extracts; Reproducibility of Results; Sensitivity and Specificity; Silybin; Silymarin; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry | 2007 |
Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system.
Topics: Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Flavonols; Glycerides; Hemolysis; In Vitro Techniques; Molecular Structure; Poloxamer; Polyethylene Glycols; Protective Agents; Quercetin; Rabbits; Silybin; Silymarin; Solubility; Technology, Pharmaceutical; Time Factors | 2007 |
Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Blotting, Western; cdc25 Phosphatases; Cell Cycle Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor Proteins; Cyclin-Dependent Kinases; Cyclins; Drug Screening Assays, Antitumor; Flavonolignans; Flow Cytometry; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Isomerism; Male; Prostatic Neoplasms; Protective Agents; Silybin; Silymarin; Time Factors | 2008 |
Influence of exogenous salicylic acid on flavonolignans and lipoxygenase activity in the hairy root cultures of Silybum marianum.
Topics: Antioxidants; Cell Culture Techniques; Flavonolignans; Linoleic Acid; Lipoxygenase; Plant Roots; Quercetin; Salicylic Acid; Silybin; Silybum marianum; Silymarin | 2009 |
Topical delivery of silymarin constituents via the skin route.
Topics: Administration, Cutaneous; Animals; Antioxidants; Diffusion Chambers, Culture; Female; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Mice, Nude; Permeability; Silybin; Silymarin; Skin Absorption; Skin Irritancy Tests; Thermodynamics; Time Factors | 2010 |
An assessment of pharmacokinetics and antioxidant activity of free silymarin flavonolignans in healthy volunteers: a dose escalation study.
Topics: Adult; Antioxidants; Dinoprost; F2-Isoprostanes; Female; Flavonolignans; Healthy Volunteers; Humans; Male; Silybin; Silybum marianum; Silymarin; Young Adult | 2013 |
Accumulation of silymarin in milk thistle seeds under drought stress.
Topics: Antioxidants; Droughts; Seeds; Silybin; Silybum marianum; Silymarin | 2015 |
Supercritical CO₂ extraction of oil, fatty acids and flavonolignans from milk thistle seeds: Evaluation of their antioxidant and cytotoxic activities in Caco-2 cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Caco-2 Cells; Carcinoma; Cell Survival; Chromatography, Supercritical Fluid; Dietary Supplements; Fatty Acids; Flavonolignans; Food Additives; Humans; Plant Oils; Seeds; Silybin; Silybum marianum; Silymarin; Tunisia | 2015 |
Flavonolignan 2,3-dehydroderivatives: Preparation, antiradical and cytoprotective activity.
Topics: Animals; Antioxidants; Cytoprotection; Electron Spin Resonance Spectroscopy; Flavonolignans; Hep G2 Cells; Humans; Male; Rats; Silybin; Silymarin; Structure-Activity Relationship | 2016 |
Variation in the flavonolignan composition of fruits from different Silybum marianum chemotypes and suspension cultures derived therefrom.
Topics: Bulgaria; Cells, Cultured; Europe; Flavonols; Fruit; Lignin; Quercetin; Silybin; Silybum marianum; Silymarin; Stereoisomerism | 2016 |
A new approach to the rapid separation of isomeric compounds in a Silybum marianum extract using UHPLC core-shell column with F5 stationary phase.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dietary Supplements; Isomerism; Plant Extracts; Silybin; Silybum marianum; Silymarin; Teas, Herbal | 2017 |
Silychristin: Skeletal Alterations and Biological Activities.
Topics: Antioxidants; Fruit; Humans; Molecular Structure; Plant Extracts; Plant Roots; Silybin; Silybum marianum; Silymarin | 2016 |
Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations.
Topics: Egypt; Flavonolignans; Fruit; Molecular Structure; Secondary Metabolism; Silybin; Silybum marianum; Silymarin | 2017 |
Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells.
Topics: Animals; Cell Line, Tumor; Gene Expression; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Humans; Membrane Proteins; Mice; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Silybin; Silybum marianum; Silymarin; Up-Regulation | 2017 |
Flavonolignans inhibit the arachidonic acid pathway in blood platelets.
Topics: Anti-Inflammatory Agents; Arachidonic Acid; Binding, Competitive; Blood Platelets; Flavonolignans; Humans; Inflammation Mediators; Malondialdehyde; Molecular Docking Simulation; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Silybin; Silybum marianum; Silymarin; Thromboxane A2 | 2017 |
Flavonolignans reduce the response of blood platelet to collagen.
Topics: Blood Coagulation; Blood Platelets; Cell Adhesion; Collagen; Flavonolignans; Hemostatics; Humans; Platelet Activation; Platelet Aggregation; Platelet Factor 4; Platelet Glycoprotein GPIIb-IIIa Complex; Silybin; Silymarin | 2018 |
Flavonolignans Inhibit IL1-β-Induced Cross-Talk between Blood Platelets and Leukocytes.
Topics: Anti-Inflammatory Agents; Blood Platelets; Cells, Cultured; Cytokines; Flavonolignans; Humans; Interleukin-1beta; Leukocytes; Platelet Aggregation Inhibitors; Silybin; Silymarin | 2017 |
Evaluation of the Cytotoxicity and Genotoxicity of Flavonolignans in Different Cellular Models.
Topics: A549 Cells; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Blood Platelets; Cell Survival; DNA Copy Number Variations; DNA Damage; DNA, Mitochondrial; Dose-Response Relationship, Drug; Flavonolignans; Fruit; Humans; Leukocytes, Mononuclear; Plant Extracts; Reactive Oxygen Species; Silybin; Silybum marianum; Silymarin | 2017 |
Inhibitory Effect of Flavonolignans on the P2Y12 Pathway in Blood Platelets.
Topics: Adenosine Diphosphate; Blood Platelets; Cell Adhesion Molecules; Fibrinogen; Flavonolignans; Humans; Microfilament Proteins; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet-Rich Plasma; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Signal Transduction; Silybin; Silymarin | 2018 |
Differential Effects of the Flavonolignans Silybin, Silychristin and 2,3-Dehydrosilybin on
Topics: Animals; Antioxidants; Hypoxia; In Vitro Techniques; Larva; Mesocestoides; Protective Agents; Silybin; Silymarin | 2018 |
Linear regression analysis of silychristin A, silybin A and silybin B contents in
Topics: Antioxidants; Biological Products; Biosynthetic Pathways; Flavonoids; Models, Theoretical; Quercetin; Regression Analysis; Silybin; Silybum marianum; Silymarin | 2020 |
Characterization of glutathione conjugates derived from reactive metabolites of seven silymarin isomers.
Topics: Animals; Cytochrome P-450 Enzyme System; Glutathione; Humans; Hydroxylation; Isomerism; Microsomes, Liver; Oxidation-Reduction; Rats; Silybin; Silymarin; Tandem Mass Spectrometry | 2019 |
Identification of UDP-glucuronosyltransferases involved in the metabolism of silymarin flavonolignans.
Topics: Adult; Cells, Cultured; Flavonolignans; Glucuronides; Glucuronosyltransferase; Hepatocytes; Humans; Male; Microsomes, Liver; Silybin; Silybum marianum; Silymarin | 2020 |