silybin has been researched along with quercetin in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 17 (42.50) | 29.6817 |
| 2010's | 14 (35.00) | 24.3611 |
| 2020's | 8 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Augereau, JM; Billon, M; Gleye, J; Herbert, JM; Lale, A; Leconte, M | 1 |
| Morris, ME; Yang, X; Zhang, S | 1 |
| Kim, YC; Sung, SH; Yang, H | 1 |
| Hille, R; Pauff, JM | 1 |
| Gong, J; Huang, K; Li, H; Li, X; Qu, J; Stöckigt, J; Tao, Q; Wang, F; Wu, X; Yang, L; Zeng, S; Zhao, Y | 1 |
| Feng, YB; Gong, JX; Huang, KX; Li, HB; Li, XK; Qu, J; Spencer, S; Tao, QF; Wang, F; Wu, XM; Wu, YH; Yang, LX; Zeng, S; Zhao, Y | 1 |
| Bartalis, J; Halaweish, FT | 1 |
| Chen, X; Decker, M; Fleck, C; Heilmann, J; Kling, B; Kraus, B; Lupp, A; Zenger, K | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Bijak, M; Krotkiewski, H; Nowak, P; Pawlaczyk, I; Ponczek, M; Saluk, J; Wachowicz, B; Ziewiecki, R | 1 |
| Di Fabio, G; Federico, A; Gravante, R; Loguercio, C; Romanucci, V; Tuccillo, C; Zarrelli, A | 1 |
| Decker, M; Gunesch, S; Högger, P; Huang, G; Lang, F; Maher, P; Roa, J; Sabaté, R; Schramm, S | 1 |
| Kalra, S; Khatik, GL; Kumar, GN; Kumar, R; Narang, R; Nayak, SK; Singh, SK; Sudhakar, K | 1 |
| Beeson, TD; Guz, NR; Hsiang, J; Johnson, JB; Lewis, K; Stermitz, FR; Willen, S | 1 |
| Matsuda, H; Nakamura, S; Nakashima, S; Oda, Y; Xu, F; Yoshikawa, M | 1 |
| Fortunato, S; Granchi, C; Minutolo, F | 1 |
| Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V | 1 |
| Carrier, DJ; Clausen, EC; Duan, L | 1 |
| Kravchenko, LV; Morozov, SV; Tutel'yan, VA | 1 |
| Hong, YJ; Huang, ZQ; Wang, YK | 1 |
| Feng, CG; Liu, X; Zhang, LX | 1 |
| Psotová, J; Svobodová, A; Walterová, D | 1 |
| Bai, H; Gong, J; Hao, X; Stöckigt, J; Wang, F; Wang, Y; Wu, X; Yang, L; Zhang, Y; Zhao, Y | 1 |
| Chen, J; Lu, C; Lu, Y; Wu, W; Zhang, W | 1 |
| Anzenbacher, P; Anzenbacherová, E; Jancová, P; Lemr, K; Luzná, P; Papousková, B; Simánek, V; Veinlichová, A | 1 |
| Bhaskar, AS; Deb, U; Jayaraj, R; Prasad, GB; Rao, PV | 1 |
| Cheon, EP; Han, HK; Kang, KW; Seo, KS; Shim, CK | 1 |
| Hasanloo, T; Kazemi Tabar, SK; Khalili, M; Rahnama, H | 1 |
| Azonpi, A; Bahem, R; Caballero-George, C; Hoffmann, A; Vanderheyden, P | 1 |
| Abu Bakar, S; Chiam, CW; Chu, JJ; Hassandarvish, P; Higgs, S; Lani, R; Merits, A; Moghaddam, E; Rausalu, K; Vanlandingham, D; Zandi, K | 1 |
| Barros, L; Ferreira, IC; José Alves, M; Pereira, C; Santos-Buelga, C | 1 |
| Petersen, M; Poppe, L | 1 |
| Abbasi, BH; Drouet, S; Giglioli-Guivarc'h, N; Hano, C; Nadeem, M; Younas, M | 1 |
| Abd El Mageed, AMA; AbouZid, SF; Ahmed, HS; Chen, SN; Friesen, JB; McAlpine, JB; Moawad, AS; Nachtergael, A; Owis, AI; Pauli, GF | 1 |
| Jin, L; Liang, G; Lv, Y; Wang, Y | 1 |
| Capasso, D; Di Fabio, G; Di Gaetano, S; Lembo, A; Pagano, R; Romanucci, V; Zarrelli, A | 1 |
| Decker, M; Gutmann, M; Hofmann, J; Maurice, T; Spatz, P; Walther, R | 1 |
| Jin, Q; Li, P; Liu, T; Ma, F; Mao, H; Ren, F; Wang, Y; Yang, L; Zhan, Y | 1 |
| Soukop, J; Večeřa, R | 1 |
| Kadoglou, NPE; Papakyriakopoulou, P; Skaltsa, H; Tomou, EM; Valsami, G | 1 |
4 review(s) available for silybin and quercetin
| Article | Year |
|---|---|
Recent advancements in mechanistic studies and structure activity relationship of F
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Proton-Translocating ATPases; Structure-Activity Relationship | 2019 |
[Progress in research of aldose reductase inhibitors in traditional medicinal herbs].
Topics: Aldehyde Reductase; Animals; Diabetic Nephropathies; Drug Combinations; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Isoflavones; Plants, Medicinal; Quercetin; Silybin; Silymarin | 2005 |
Potential therapeutic effects of natural compounds targeting autophagy to alleviate podocyte injury in glomerular diseases.
Topics: Artemisinins; Autophagy; Humans; Kaempferols; Kidney Diseases; Podocytes; Quercetin; Silybin; Transcription Factors | 2022 |
Bio-Actives from Natural Products with Potential Cardioprotective Properties: Isolation, Identification, and Pharmacological Actions of Apigenin, Quercetin, and Silibinin.
Topics: Apigenin; Biological Products; Cardiovascular Diseases; Humans; Quercetin; Risk Factors; Silybin | 2023 |
36 other study(ies) available for silybin and quercetin
| Article | Year |
|---|---|
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
Topics: Amino Acid Sequence; Blood Coagulation; Cell Adhesion; Endotoxins; Flavonoids; Humans; In Vitro Techniques; Interleukin-1; Molecular Sequence Data; Monocytes | 1996 |
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Division; Chemokines, CC; Dose-Response Relationship, Drug; Drug Interactions; Flavonoids; Humans; Mitoxantrone; Neoplasm Proteins; Tumor Cells, Cultured | 2004 |
Two new hepatoprotective stilbene glycosides from Acer mono leaves.
Topics: Acer; Animals; Glucosides; Glycosides; Hepatocytes; Hydrogen Peroxide; Korea; Male; Plant Leaves; Plants, Medicinal; Quercetin; Rats; Rats, Wistar; Stilbenes | 2005 |
Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin.
Topics: Animals; Cattle; Curcumin; Luteolin; Molecular Structure; Molybdenum; Purines; Quercetin; Silybin; Silymarin; Superoxides; Xanthine; Xanthine Oxidase | 2009 |
Preparation of C-23 esterified silybin derivatives and evaluation of their lipid peroxidation inhibitory and DNA protective properties.
Topics: Animals; DNA Damage; Free Radical Scavengers; Lipid Peroxidation; Rats; Silybin; Silymarin; Structure-Activity Relationship | 2009 |
Design, synthesis, and examination of neuron protective properties of alkenylated and amidated dehydro-silybin derivatives.
Topics: Alkenes; Alzheimer Disease; Amides; Animals; Drug Design; Free Radical Scavengers; Humans; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Models, Molecular; Molecular Conformation; Neurons; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Rats; Silymarin; Structure-Activity Relationship; Xanthine Oxidase | 2009 |
In vitro and QSAR studies of cucurbitacins on HepG2 and HSC-T6 liver cell lines.
Topics: Animals; Cell Line; Cell Proliferation; Cucurbitacins; Fibrosis; Hep G2 Cells; Hepatic Stellate Cells; Humans; Hydrophobic and Hydrophilic Interactions; Liver; Protective Agents; Quantitative Structure-Activity Relationship; Rats | 2011 |
Tacrine-silibinin codrug shows neuro- and hepatoprotective effects in vitro and pro-cognitive and hepatoprotective effects in vivo.
Topics: Acetylcholinesterase; Allosteric Regulation; Animals; Butyrylcholinesterase; Cell Count; Cell Line; Cell Survival; Cholinesterase Inhibitors; Cognition; Eels; Female; Glutamic Acid; Hepatic Stellate Cells; Horses; Lipid Peroxidation; Liver; Maze Learning; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Silybin; Silymarin; Tacrine | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Thrombin inhibitory activity of some polyphenolic compounds.
Topics: | 2014 |
New silibinin glyco-conjugates: synthesis and evaluation of antioxidant properties.
Topics: Antioxidants; Cell Death; Cell Line, Tumor; Drug Evaluation; Free Radical Scavengers; Glycogen; Humans; Silybin; Silybum marianum; Silymarin | 2014 |
Regioselective synthesis of 7-O-esters of the flavonolignan silibinin and SARs lead to compounds with overadditive neuroprotective effects.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Esters; Flavonolignans; Humans; Molecular Structure; Neuroprotective Agents; PC12 Cells; Protein Aggregates; Rats; Silybin; Silymarin; Stereoisomerism; Structure-Activity Relationship | 2018 |
Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Drug Resistance, Microbial; Drug Resistance, Multiple; Flavonoids; Lignans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship | 2001 |
Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.
Topics: Agaricales; Animals; Antineoplastic Agents; Brassicaceae; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Intramolecular Oxidoreductases; Melanoma, Experimental; Membrane Glycoproteins; Mice; Monophenol Monooxygenase; Oxidoreductases; Plant Extracts; RNA, Messenger; Structure-Activity Relationship; Tumor Cells, Cultured | 2010 |
Anticancer agents interacting with membrane glucose transporters.
Topics: | 2016 |
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins | 2020 |
Silymarin extraction from milk thistle using hot water.
Topics: Biotechnology; Flavonols; Hot Temperature; Kinetics; Models, Chemical; Quercetin; Silybin; Silybum marianum; Silymarin; Solvents; Temperature; Time Factors; Water | 2004 |
Effects of flavonoids on the resistance of microsomes to lipid peroxidation in vitro and ex vivo.
Topics: Animals; Antioxidants; Flavonoids; Flavonols; Larix; Lipid Peroxidation; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Plant Extracts; Quercetin; Rats; Rats, Wistar; Silybin; Silybum marianum; Silymarin; Thiobarbituric Acid Reactive Substances; Vitis | 2003 |
Protective effects of silybin on human umbilical vein endothelial cell injury induced by H2O2 in vitro.
Topics: Antioxidants; Caspase 3; Caspases; Cell Survival; Endothelial Cells; Epithelial Cells; Fibroblasts; Glomerular Mesangium; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Immunohistochemistry; L-Lactate Dehydrogenase; Malondialdehyde; Nitric Oxide; Oxidants; Quercetin; Silybin; Silymarin; Umbilical Veins | 2005 |
Influence of silymarin and its flavonolignans on H(2)O(2)-induced oxidative stress in human keratinocytes and mouse fibroblasts.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Flavonolignans; Flavonols; Humans; Hydrogen Peroxide; Keratinocytes; Mice; Mice, Inbred BALB C; Oxidants; Oxidative Stress; Phytotherapy; Plant Extracts; Protective Agents; Quercetin; Silybin; Silymarin | 2006 |
Synthesis and antioxidant evaluation of novel silybin analogues.
Topics: Anions; Antioxidants; Biphenyl Compounds; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Free Radical Scavengers; Hydrazines; Inhibitory Concentration 50; Models, Chemical; Picrates; Quercetin; Silybin; Silymarin; Spectrophotometry; Superoxides | 2006 |
Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system.
Topics: Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Flavonols; Glycerides; Hemolysis; In Vitro Techniques; Molecular Structure; Poloxamer; Polyethylene Glycols; Protective Agents; Quercetin; Rabbits; Silybin; Silymarin; Solubility; Technology, Pharmaceutical; Time Factors | 2007 |
Silybin is metabolized by cytochrome P450 2C8 in vitro.
Topics: Antioxidants; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Escherichia coli; Humans; Microsomes, Liver; Molecular Structure; Quercetin; Recombinant Proteins; Silybin; Silymarin | 2007 |
Hepatoprotective efficacy of certain flavonoids against microcystin induced toxicity in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bacterial Toxins; Catalase; Flavonoids; Glutathione; Glutathione Peroxidase; Glutathione Reductase; L-Lactate Dehydrogenase; Liver; Marine Toxins; Mice; Microcystins; Phosphoric Monoester Hydrolases; Protective Agents; Quercetin; Silybin; Silymarin | 2007 |
Inhibition effect of flavonoids on monocarboxylate transporter 1 (MCT1) in Caco-2 cells.
Topics: Benzoic Acid; Biological Transport; Blotting, Western; Caco-2 Cells; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Food-Drug Interactions; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Lactic Acid; Monocarboxylic Acid Transporters; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; Silybin; Silymarin; Symporters | 2007 |
Influence of exogenous salicylic acid on flavonolignans and lipoxygenase activity in the hairy root cultures of Silybum marianum.
Topics: Antioxidants; Cell Culture Techniques; Flavonolignans; Linoleic Acid; Lipoxygenase; Plant Roots; Quercetin; Salicylic Acid; Silybin; Silybum marianum; Silymarin | 2009 |
Modulation of Calcium Signaling of Angiotensin AT1, Endothelin ETA, and ETB Receptors by Silibinin, Quercetin, Crocin, Diallyl Sulfides, and Ginsenoside Rb1.
Topics: Allyl Compounds; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Calcium Signaling; Carotenoids; CHO Cells; Cricetinae; Cricetulus; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Ginsenosides; Humans; Quercetin; Receptors, Angiotensin; Receptors, Endothelin; Silybin; Silymarin; Sulfides | 2015 |
Antiviral activity of silymarin against chikungunya virus.
Topics: Animals; Antiviral Agents; Cell Line; Chikungunya virus; Chlorocebus aethiops; Cricetulus; Dose-Response Relationship, Drug; Epithelial Cells; Kaempferols; Quercetin; RNA, Viral; Silybin; Silymarin; Vero Cells; Viral Load; Virus Replication | 2015 |
Artichoke and milk thistle pills and syrups as sources of phenolic compounds with antimicrobial activity.
Topics: Anti-Infective Agents; Antioxidants; Cynara scolymus; Dietary Supplements; Disaccharides; Escherichia coli; Flavonoids; Luteolin; Methicillin-Resistant Staphylococcus aureus; Phenol; Plant Preparations; Proteus mirabilis; Pseudomonas aeruginosa; Quercetin; Quinic Acid; Silybin; Silybum marianum; Silymarin; Vanillic Acid | 2016 |
Variation in the flavonolignan composition of fruits from different Silybum marianum chemotypes and suspension cultures derived therefrom.
Topics: Bulgaria; Cells, Cultured; Europe; Flavonols; Fruit; Lignin; Quercetin; Silybin; Silybum marianum; Silymarin; Stereoisomerism | 2016 |
Differential accumulation of silymarin induced by exposure of Silybum marianum L. callus cultures to several spectres of monochromatic lights.
Topics: Cells, Cultured; Light; Plant Leaves; Quercetin; Silybin; Silymarin | 2018 |
Linear regression analysis of silychristin A, silybin A and silybin B contents in
Topics: Antioxidants; Biological Products; Biosynthetic Pathways; Flavonoids; Models, Theoretical; Quercetin; Regression Analysis; Silybin; Silybum marianum; Silymarin | 2020 |
Revealing the Mechanism of EGCG, Genistein, Rutin, Quercetin, and Silibinin Against hIAPP Aggregation via Computational Simulations.
Topics: Catechin; Diabetes Mellitus, Type 2; Genistein; Humans; Islet Amyloid Polypeptide; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Quercetin; Rutin; Silybin | 2020 |
Phosphodiester Silybin Dimers Powerful Radical Scavengers: A Antiproliferative Activity on Different Cancer Cell Lines.
Topics: Antioxidants; Cell Line; Neoplasms; Quercetin; Silybin; Silymarin | 2022 |
Synthesis and Biological Evaluation of Flavonoid-Cinnamic Acid Amide Hybrids with Distinct Activity against Neurodegeneration in Vitro and in Vivo.
Topics: Alzheimer Disease; Amides; Animals; Biological Products; Cinnamates; Flavonoids; Mice; Quercetin; Silybin | 2022 |
Selected polyphenolic compounds and their use as a supportive therapy in metabolic syndrome.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Antioxidants; Child; Diosmin; Hesperidin; Humans; Metabolic Syndrome; Quercetin; Silybin | 2022 |