Compounds > silybin
Page last updated: 2024-08-23

silybin and malondialdehyde

silybin has been researched along with malondialdehyde in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's0 (0.00)18.2507
2000's4 (25.00)29.6817
2010's9 (56.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Guerra, R; Valenzuela, A1
Beccarello, A; Crepaldi, G; De Monte, A; Donadon, V; Lirussi, F; Velussi, M; Zanette, G1
Hong, YJ; Huang, ZQ; Wang, YK1
Ikejima, T; Onodera, S; Tashiro, S; Uchiumi, F; Wu, LJ; Zhou, B1
Hiramatsu, M; Ikejima, T; Lu, LL; Lu, P; Mamiya, T; Mouri, A; Nabeshima, T; Nagai, T; Zou, L1
Meng, Q; Ruan, X; Shen, C1
Kamat, PK; Nath, C; Shukla, R; Tota, S1
Dernawi, Y; Essid, E; Petzinger, E1
Šimánek, V; Stuchlík, M; Ulrichová, J; Vacek, J; Valentová, K; Vidlář, A; Zatloukalová, M1
Carratù, MR; de Bari, O; Diogo, CV; Ferri, D; Grattagliano, I; Liquori, A; Mastrodonato, M; Oliveira, PJ; Persichella, M; Portincasa, P; Wang, DQ1
Beydogan, AB; Bolkent, S1
Bijak, M; Saluk-Bijak, J1
Bagheri, HS; Fathi, F; Garjani, A; Malekinejad, H; Montaseri, A; Rahbarghazi, R; Rezabakhsh, A1
Hayashi, T; Ikejima, T; Liu, B; Liu, P; Liu, W; Liu, X; Onodera, S; Song, X1
Chen, YH; Hou, JW; Li, YG; Lin, H; Mao, ZJ; Wang, Q1
Shu, S; Wang, H; Wang, Q; Xu, Z1

Trials

3 trial(s) available for silybin and malondialdehyde

ArticleYear
Silybin-beta-cyclodextrin in the treatment of patients with diabetes mellitus and alcoholic liver disease. Efficacy study of a new preparation of an anti-oxidant agent.
    Diabetes, nutrition & metabolism, 2002, Volume: 15, Issue:4

    Topics: Antioxidants; beta-Cyclodextrins; Blood Glucose; C-Peptide; Cholesterol, HDL; Cyclodextrins; Diabetes Mellitus, Type 2; Double-Blind Method; Female; gamma-Glutamyltransferase; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Liver Diseases, Alcoholic; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Placebos; Silybin; Silymarin; Triglycerides

2002
Biosafety and antioxidant effects of a beverage containing silymarin and arginine. A pilot, human intervention cross-over trial.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 56

    Topics: Adult; Antioxidants; Arginine; Beverages; Catalase; Cross-Over Studies; Dietary Supplements; Erythrocytes; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Humans; Male; Malondialdehyde; Middle Aged; Pilot Projects; Silybin; Silymarin; Superoxide Dismutase

2013
Danshao Shugan Granule therapy for non-alcoholic fatty liver disease.
    Lipids in health and disease, 2022, Aug-23, Volume: 21, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholesterol; Humans; Liver; Malondialdehyde; Medicine, Chinese Traditional; Mice; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Rosiglitazone; Silybin; Superoxide Dismutase; Triglycerides

2022

Other Studies

13 other study(ies) available for silybin and malondialdehyde

ArticleYear
Protective effect of the flavonoid silybin dihemisuccinate on the toxicity of phenylhydrazine on rat liver.
    FEBS letters, 1985, Feb-25, Volume: 181, Issue:2

    Topics: Animals; Flavonoids; Glutathione; Kinetics; Lipid Peroxides; Liver; Male; Malondialdehyde; Oxygen Consumption; Phenylhydrazines; Rats; Rats, Inbred Strains; Silybin; Silymarin

1985
Protective effects of silybin on human umbilical vein endothelial cell injury induced by H2O2 in vitro.
    Vascular pharmacology, 2005, Volume: 43, Issue:4

    Topics: Antioxidants; Caspase 3; Caspases; Cell Survival; Endothelial Cells; Epithelial Cells; Fibroblasts; Glomerular Mesangium; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Immunohistochemistry; L-Lactate Dehydrogenase; Malondialdehyde; Nitric Oxide; Oxidants; Quercetin; Silybin; Silymarin; Umbilical Veins

2005
[Protective effect of silibinin against isoproterenol-induced injury to cardiac myocytes and its mechanism].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:3

    Topics: Animals; Animals, Newborn; bcl-2-Associated X Protein; Blotting, Western; Cardiotonic Agents; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Isoproterenol; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocytes, Cardiac; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Silybin; Silybum marianum; Silymarin; Sirtuin 1; Sirtuins; Superoxide Dismutase; Up-Regulation

2007
Silibinin prevents amyloid beta peptide-induced memory impairment and oxidative stress in mice.
    British journal of pharmacology, 2009, Volume: 157, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Exploratory Behavior; Glutathione; Hippocampus; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Mice, Inbred ICR; Motor Activity; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Recognition, Psychology; Silybin; Silymarin

2009
Establishment of a methodology for investigating protectants against ethanol-induced hepatotoxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:5

    Topics: Animals; Antioxidants; Cell Culture Techniques; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chemoprevention; Ethanol; Fenofibrate; Hepatocytes; Hypolipidemic Agents; Male; Malondialdehyde; Nanoparticles; Nanotechnology; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Silybin; Silybum marianum; Silymarin

2010
Improvement of brain energy metabolism and cholinergic functions contributes to the beneficial effects of silibinin against streptozotocin induced memory impairment.
    Behavioural brain research, 2011, Aug-01, Volume: 221, Issue:1

    Topics: Acetylcholinesterase; Adenosine Triphosphate; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antioxidants; Brain; Calcium; Disease Models, Animal; Drug Evaluation, Preclinical; Energy Metabolism; Glutathione; Male; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Motor Activity; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Receptors, Nicotinic; Silybin; Silymarin; Streptozocin; Synaptosomes

2011
Apoptosis induction by OTA and TNF-α in cultured primary rat hepatocytes and prevention by silibinin.
    Toxins, 2012, Nov-02, Volume: 4, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cell Culture Techniques; Cell Survival; Cells, Cultured; Chromatin; Dactinomycin; DNA Fragmentation; Hepatocytes; Hydrogen Peroxide; Lipid Peroxidation; Male; Malondialdehyde; Ochratoxins; Oxidative Stress; Protein Binding; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor, Type I; Silybin; Silymarin; Tumor Necrosis Factor-alpha; Ultraviolet Rays

2012
A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes.
    World journal of gastroenterology, 2013, May-28, Volume: 19, Issue:20

    Topics: Animals; Biomarkers; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Glutathione; Glutathione Peroxidase; Keratin-18; Liver; Male; Malondialdehyde; Mitochondria, Liver; Mitochondrial Proteins; Nitroso Compounds; Oxidative Phosphorylation; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Silybin; Silymarin; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Thioredoxins; Time Factors; Tyrosine; Vitamin E

2013
The effects of silibin administration for different time periods on mouse liver with Ehrlich ascites carcinoma.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:3

    Topics: Animals; Apoptosis; Autoantibodies; Carcinoma, Ehrlich Tumor; Caspases; Drug Administration Schedule; Liver; Male; Malondialdehyde; Matrix Metalloproteinases; Mice; Proliferating Cell Nuclear Antigen; Silybin; Silymarin; Superoxide Dismutase

2016
Flavonolignans inhibit the arachidonic acid pathway in blood platelets.
    BMC complementary and alternative medicine, 2017, Aug-10, Volume: 17, Issue:1

    Topics: Anti-Inflammatory Agents; Arachidonic Acid; Binding, Competitive; Blood Platelets; Flavonolignans; Humans; Inflammation Mediators; Malondialdehyde; Molecular Docking Simulation; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Silybin; Silybum marianum; Silymarin; Thromboxane A2

2017
Silibinin protects human endothelial cells from high glucose-induced injury by enhancing autophagic response.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:10

    Topics: Autophagy; Blotting, Western; Cell Movement; Cell Survival; Endothelial Cells; Glucose; Human Umbilical Vein Endothelial Cells; Humans; L-Lactate Dehydrogenase; Malondialdehyde; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Silybin; Thiobarbituric Acid Reactive Substances

2018
Silibinin Alleviates the Learning and Memory Defects in Overtrained Rats Accompanying Reduced Neuronal Apoptosis and Senescence.
    Neurochemical research, 2019, Volume: 44, Issue:8

    Topics: Aging; Animals; Apoptosis; Catalase; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neuroprotective Agents; Oxidative Stress; Physical Conditioning, Animal; Rats, Sprague-Dawley; Silybin; Superoxide Dismutase

2019
Protective role of silibinin against myocardial ischemia/reperfusion injury-induced cardiac dysfunction.
    International journal of biological sciences, 2020, Volume: 16, Issue:11

    Topics: Animals; Caspases; Cell Line; Cell Survival; Gene Expression Regulation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Myocytes, Cardiac; Nitriles; Protective Agents; Reactive Oxygen Species; Reperfusion Injury; Silybin; Sulfones

2020