Compounds > silybin
Page last updated: 2024-08-23

silybin and khellin

silybin has been researched along with khellin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Cho, JW; Il, KJ; Lee, KS1
Choi, S; Ham, S; Kim, J; Lee, JH; Lee, WJ; Lee, YI1

Other Studies

4 other study(ies) available for silybin and khellin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Downregulation of type I collagen expression in silibinin-treated human skin fibroblasts by blocking the activation of Smad2/3-dependent signaling pathways: potential therapeutic use in the chemoprevention of keloids.
    International journal of molecular medicine, 2013, Volume: 31, Issue:5

    Topics: Cell Death; Cell Nucleus; Cell Proliferation; Chemoprevention; Collagen Type I; Down-Regulation; Fibroblasts; Humans; Keloid; Matrix Metalloproteinases; Phosphorylation; Promoter Regions, Genetic; Signal Transduction; Silybin; Silymarin; Skin; Smad Proteins; Smad2 Protein; Smad3 Protein; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1

2013
Silibinin Downregulates Types I and III Collagen Expression via Suppression of the mTOR Signaling Pathway.
    International journal of molecular sciences, 2023, Sep-21, Volume: 24, Issue:18

    Topics: Animals; Collagen; Collagen Type I; Humans; Keloid; Mammals; Signal Transduction; Silybin; TOR Serine-Threonine Kinases

2023