silybin has been researched along with isoproterenol in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ikejima, T; Onodera, S; Tashiro, S; Uchiumi, F; Wu, LJ; Zhou, B | 3 |
| Ikejima, T; Li, LH; Onodera, S; Tashiro, S; Uchiumi, F; Wu, LJ; Zhou, B | 1 |
5 other study(ies) available for silybin and isoproterenol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Silibinin protects rat cardiac myocyte from isoproterenol-induced DNA damage independent on regulation of cell cycle.
Topics: Animals; Apoptosis; Caspases; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Isoproterenol; Myocytes, Cardiac; Nitric Oxide; Rats; Rats, Sprague-Dawley; Silybin; Silymarin; Tumor Suppressor Protein p53 | 2006 |
Silibinin protects against isoproterenol-induced rat cardiac myocyte injury through mitochondrial pathway after up-regulation of SIRT1.
Topics: Adrenergic beta-Agonists; Aldehydes; Animals; Animals, Newborn; bcl-2-Associated X Protein; bcl-X Protein; Calcium; Cell Survival; Cells, Cultured; Cytochromes c; Dose-Response Relationship, Drug; Isoproterenol; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocytes, Cardiac; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Silybin; Silymarin; Sirtuin 1; Sirtuins; Superoxide Dismutase; Up-Regulation | 2006 |
Activation of extracellular signal-regulated kinase during silibinin-protected, isoproterenol-induced apoptosis in rat cardiac myocytes is tyrosine kinase pathway-mediated and protein kinase C-dependent.
Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Isoproterenol; JNK Mitogen-Activated Protein Kinases; Molecular Structure; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Silybin; Silymarin | 2007 |
[Protective effect of silibinin against isoproterenol-induced injury to cardiac myocytes and its mechanism].
Topics: Animals; Animals, Newborn; bcl-2-Associated X Protein; Blotting, Western; Cardiotonic Agents; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Isoproterenol; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocytes, Cardiac; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Silybin; Silybum marianum; Silymarin; Sirtuin 1; Sirtuins; Superoxide Dismutase; Up-Regulation | 2007 |