silybin has been researched along with isoniazid in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Kalra, S; Khatik, GL; Kumar, GN; Kumar, R; Narang, R; Nayak, SK; Singh, SK; Sudhakar, K | 1 |
| Karthikeyan, S; Raghu, R | 1 |
| Decker, M; Lupp, A; Mann, A; Mosig, A; Pelz, T; Rennert, K | 1 |
| Ramanathan, R; Sivanesan, K | 1 |
| Goh, ZH; Ho, HK; Tee, JK | 1 |
2 review(s) available for silybin and isoniazid
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
Recent advancements in mechanistic studies and structure activity relationship of F
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Proton-Translocating ATPases; Structure-Activity Relationship | 2019 |
5 other study(ies) available for silybin and isoniazid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Zidovudine and isoniazid induced liver toxicity and oxidative stress: Evaluation of mitigating properties of silibinin.
Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Drug Synergism; Female; Isoniazid; Liver Function Tests; Male; Oxidative Stress; Rats, Wistar; Silybin; Silymarin; Zidovudine | 2016 |
Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance.
Topics: Antitubercular Agents; Aspartate Aminotransferases; Caspase 3; Cell Survival; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glutathione; Hep G2 Cells; Humans; Isoniazid; Lactate Dehydrogenases; Liver; Oxidative Stress; Silybin; Silymarin | 2017 |
Evaluation of ameliorative ability of Silibinin against zidovudine and isoniazid-induced hepatotoxicity and hyperlipidaemia in rats: Role of Silibinin in Phase I and II drug metabolism.
Topics: Adipose Tissue; Animals; Dose-Response Relationship, Drug; Female; Hyperlipidemias; Isoniazid; Lipids; Liver; Male; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Rats; Rats, Wistar; Silybin; Silymarin; Structure-Activity Relationship; Zidovudine | 2017 |
An Evaluation of the In Vitro Roles and Mechanisms of Silibinin in Reducing Pyrazinamide- and Isoniazid-Induced Hepatocellular Damage.
Topics: Antitubercular Agents; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Hepatocytes; Humans; Isoniazid; Oxidative Stress; Protective Agents; Protein Carbonylation; Pyrazinamide; Silybin | 2020 |