silybin has been researched along with d-alpha tocopherol in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 16 (76.19) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| El-Bahay, C; Hanelt, S; Kahl, R; Lewerenz, V; Nastevska, C; Röhrdanz, E | 1 |
| D'Auria, M; de Sio, I; Di Leva, A; Federico, A; Loguercio, C; Niosi, M; Trappoliere, M; Tuccillo, C | 1 |
| de Sio, I; Del Vecchio Blanco, C; Di Leva, A; Federico, A; Loguercio, C; Trappoliere, M; Tuccillo, C | 1 |
| Capasso, R; D'Auria, MV; de Sio, I; Del Vecchio Blanco, C; Di Leva, A; Federico, A; Loguercio, C; Niosi, M; Trappoliere, M; Tuccillo, C | 1 |
| Conti, P; De Tullio, D; Falasca, K; Mancino, P; Pizzigallo, E; Ucciferri, C; Vecchiet, J; Vitacolonna, E | 1 |
| Baba, HA; Benko, T; Best, J; de Groot, H; Fandrey, J; Frede, S; Gu, Y; Rauen, U; Schlaak, JF | 1 |
| Di Cesare Mannelli, L; Failli, P; Ghelardini, C; Zanardelli, M | 2 |
| Andreone, P; Brisc, C; Brisc, MC; Bugianesi, E; Chiaramonte, M; Cursaro, C; Danila, M; de Sio, I; Del Vecchio Blanco, C; Federico, A; Floreani, A; Freni, MA; Grieco, A; Groppo, M; Lazzari, R; Lobello, S; Loguercio, C; Lorefice, E; Margotti, M; Miele, L; Milani, S; Okolicsanyi, L; Palasciano, G; Portincasa, P; Saltarelli, P; Smedile, A; Somalvico, F; Sorrentino, P; Spadaro, A; Sporea, I; Tuccillo, C; Vecchione, R | 1 |
| Bubley, G; Klempner, SJ | 1 |
| Nambiar, D; Singh, RP | 1 |
| Carratù, MR; de Bari, O; Diogo, CV; Ferri, D; Grattagliano, I; Liquori, A; Mastrodonato, M; Oliveira, PJ; Persichella, M; Portincasa, P; Wang, DQ | 1 |
| Chen, L; Li, Y; Shen, J; Xu, P; Yin, Q; Yu, H; Zhang, Z | 1 |
| Hadjipavlou, M; Khan, S; Philippou, Y; Rane, A | 1 |
| Bosch-Barrera, J; Brunet, J; Corominas-Faja, B; Cuyàs, E; Martin-Castillo, B; Menendez, JA | 1 |
| Abenavoli, L; Accattato, F; Foti, D; Greco, M; Gulletta, E; Luzza, F; Milic, N; Nazionale, I; Peta, V | 1 |
| Hashem, RM; Hassan, MG; Hassanin, KM; Mahmoud, MO; Rashed, LA | 1 |
| Baldini, F; Grasselli, E; Grattagliano, I; Portincasa, P; Vecchione, G; Vergani, L; Voci, A; Wang, DQ | 1 |
| Addesi, D; Cassano, V; Maio, R; Perticone, F; Perticone, M; Sciacqua, A; Sesti, G; Tripepi, G | 1 |
| Cossiga, V; Dallio, M; Di Sarno, R; Federico, A; Gravina, AG; Lama, S; Loguercio, C; Masarone, M; Morisco, F; Persico, M; Stiuso, P; Tuccillo, C | 1 |
3 review(s) available for silybin and d-alpha tocopherol
| Article | Year |
|---|---|
Complementary and alternative medicines in prostate cancer: from bench to bedside?
Topics: Antioxidants; Beverages; Complementary Therapies; Curcuma; Humans; Lythraceae; Male; Plant Extracts; Prostatic Neoplasms; Resveratrol; Selenium; Silybin; Silymarin; Stilbenes; Tea; Vitamin E; Vitamins | 2012 |
Advances in prostate cancer chemoprevention: a translational perspective.
Topics: Androgen Antagonists; Animals; Anticarcinogenic Agents; Antioxidants; Azasteroids; Carotenoids; Chemoprevention; Clinical Trials as Topic; Curcumin; Disease Models, Animal; Dutasteride; Finasteride; Flavonoids; Genistein; Humans; Lycopene; Male; Phytochemicals; Polyphenols; Prostate; Prostatic Neoplasms; Risk Factors; Selenium; Silybin; Silymarin; Tea; Vitamin E | 2013 |
Complementary and alternative medicine (CAM) in prostate and bladder cancer.
Topics: Acupuncture; Antineoplastic Agents; Antioxidants; Camellia sinensis; Complementary Therapies; Drugs, Chinese Herbal; Female; Humans; Male; Plant Extracts; Prostatic Neoplasms; Resveratrol; Selenium; Silybin; Silymarin; Stilbenes; Urinary Bladder Neoplasms; Vitamin E; Vitamins | 2013 |
5 trial(s) available for silybin and d-alpha tocopherol
| Article | Year |
|---|---|
[Effects of a new pharmacological complex (silybin + vitamin-E + phospholipids) on some markers of the metabolic syndrome and of liver fibrosis in patients with hepatic steatosis. Preliminary study].
Topics: Adult; Aged; Biomarkers; Drug Combinations; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; Phospholipids; Pilot Projects; Silybin; Silymarin; Vitamin E | 2005 |
A new silybin-vitamin E-phospholipid complex improves insulin resistance and liver damage in patients with non-alcoholic fatty liver disease: preliminary observations.
Topics: Drug Combinations; Fatty Liver; Humans; Insulin Resistance; Phospholipids; Silybin; Silymarin; Vitamin E | 2006 |
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial.
Topics: Body Mass Index; Fatty Liver; Humans; Phosphatidylcholines; Romania; Silybin; Silymarin; Vitamin E | 2012 |
Effects of Mediterranean diet supplemented with silybin-vitamin E-phospholipid complex in overweight patients with non-alcoholic fatty liver disease.
Topics: Adult; Biomarkers; Body Mass Index; Cholesterol; Diet, Mediterranean; Dietary Supplements; Humans; Italy; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Overweight; Phosphatidylcholines; Prospective Studies; Silybin; Silymarin; Time Factors; Treatment Outcome; Triglycerides; Vitamin E; Waist Circumference | 2015 |
Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients.
Topics: Adult; Aged; Biomarkers; Body Weight; Cytokines; Drug Therapy, Combination; Endothelial Cells; Female; Humans; Insulin Resistance; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Silybin; Vitamin D; Vitamin E | 2019 |
13 other study(ies) available for silybin and d-alpha tocopherol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Antioxidants protect primary rat hepatocyte cultures against acetaminophen-induced DNA strand breaks but not against acetaminophen-induced cytotoxicity.
Topics: Acetaminophen; Acetylcysteine; alpha-Tocopherol; Analgesics, Non-Narcotic; Animals; Antioxidants; Blotting, Northern; Cell Death; Chemical and Drug Induced Liver Injury; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Formazans; Hepatocytes; Lipid Peroxides; Liver Diseases; Male; Neutral Red; Rats; Rats, Wistar; RNA; Silybin; Silymarin; Tetrazolium Salts | 2003 |
The effect of a silybin-vitamin e-phospholipid complex on nonalcoholic fatty liver disease: a pilot study.
Topics: Adult; Aged; Antioxidants; Cytokines; Disease Progression; Drug Therapy, Combination; Fatty Liver; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phospholipids; Pilot Projects; Silybin; Silybum marianum; Silymarin; Time Factors; Transaminases; Treatment Outcome; Ultrasonography; Vitamin E | 2007 |
Treatment with silybin-vitamin E-phospholipid complex in patients with hepatitis C infection.
Topics: Adult; Aged; Alanine Transaminase; Anti-Inflammatory Agents; Aspartate Aminotransferases; Cytokines; Female; Hepatitis C; Humans; Liver Function Tests; Male; Middle Aged; Silybin; Silymarin; Treatment Outcome; Viral Load; Vitamin E | 2008 |
Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat.
Topics: Alanine Transaminase; alpha-Tocopherol; Animals; Aspartate Aminotransferases; Drug Evaluation, Preclinical; Drug Synergism; Glycine; Hepatectomy; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Diseases; Liver Transplantation; Male; Postoperative Complications; Preanesthetic Medication; Prothrombin Time; Random Allocation; Rats; Rats, Wistar; Silybin; Silymarin; Tissue and Organ Harvesting | 2010 |
Oxaliplatin-induced neuropathy: oxidative stress as pathological mechanism. Protective effect of silibinin.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Antioxidants; Disease Models, Animal; Male; Organoplatinum Compounds; Oxaliplatin; Oxidative Stress; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Silybin; Silymarin | 2012 |
Oxaliplatin-induced oxidative stress in nervous system-derived cellular models: could it correlate with in vivo neuropathy?
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Neurotoxicity Syndromes; Organoplatinum Compounds; Oxaliplatin; Oxidative Stress; Rats; Silybin; Silymarin; Vitamin E | 2013 |
A silybin-phospholipids complex counteracts rat fatty liver degeneration and mitochondrial oxidative changes.
Topics: Animals; Biomarkers; Choline Deficiency; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Glutathione; Glutathione Peroxidase; Keratin-18; Liver; Male; Malondialdehyde; Mitochondria, Liver; Mitochondrial Proteins; Nitroso Compounds; Oxidative Phosphorylation; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Silybin; Silymarin; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances; Thioredoxins; Time Factors; Tyrosine; Vitamin E | 2013 |
Synergistic inhibition of breast cancer metastasis by silibinin-loaded lipid nanoparticles containing TPGS.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Carriers; Drug Synergism; Female; Humans; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Nude; Nanoparticles; Neoplasm Invasiveness; Particle Size; Phosphatidylcholines; Polyethylene Glycols; Silybin; Silymarin; Snail Family Transcription Factors; Solubility; Technology, Pharmaceutical; Time Factors; Tissue Distribution; Transcription Factors; Vitamin E; Wound Healing; Xenograft Model Antitumor Assays | 2013 |
Silibinin administration improves hepatic failure due to extensive liver infiltration in a breast cancer patient.
Topics: Adult; Breast Neoplasms; Female; Humans; Liver; Liver Failure; Silybin; Silymarin; Vitamin E | 2014 |
Effect of silibinin and vitamin E on the ASK1-p38 MAPK pathway in D-galactosamine/lipopolysaccharide induced hepatotoxicity.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Galactosamine; Histocytochemistry; Lipopolysaccharides; Liver; Liver Function Tests; MAP Kinase Kinase Kinase 5; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Signal Transduction; Silybin; Silymarin; Treatment Outcome; Vitamin E | 2016 |
Silybin counteracts lipid excess and oxidative stress in cultured steatotic hepatic cells.
Topics: Animals; Antioxidants; Blotting, Western; Carnitine O-Palmitoyltransferase; Catalase; Cell Line, Tumor; Cells, Cultured; Fatty Liver; Fluorometry; Hepatocytes; Lipid Droplets; Lipid Metabolism; Lipid Peroxidation; Microscopy, Fluorescence; NF-kappa B; Oleic Acid; Oxidative Stress; Palmitates; Peroxisome Proliferator-Activated Receptors; Rats; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Silybin; Silymarin; Spectrophotometry; Sterol Regulatory Element Binding Protein 1; Triglycerides; Vitamin E | 2016 |
Metabolic and vascular effects of silybin in hypertensive patients with high 1-h post-load plasma glucose.
Topics: Adult; Blood Glucose; Drug Combinations; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin Resistance; Longitudinal Studies; Male; Middle Aged; Phospholipids; Pilot Projects; Protective Agents; Silybin; Treatment Outcome; Vitamin E | 2019 |