Compounds > silybin
Page last updated: 2024-08-23

silybin and cytochrome c-t

silybin has been researched along with cytochrome c-t in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahn, BW; Ahn, SJ; Hwang, YS; Jeong, M; Jung, SN; Jung, YD; Kim, MH; Park, JS; Park, RK; Shin, BA; Yoo, HG1
Baliga, MS; Katiyar, SK; Roy, AM1
Ikejima, T; Li, LH; Onodera, S; Tashiro, S; Uchiumi, F; Wu, LJ1
Agarwal, C; Agarwal, R; Singh, RP; Tyagi, A1
Ikejima, T; Li, LH; Onodera, S; Tashiro, S; Uchiumi, F; Wu, LJ; Zhou, B1
Chen, Y; He, D; Li, L; Sun, Y; Wang, X; Wang, Z; Wu, K; Xue, Y; Yang, Z; Zeng, J; Zhang, D; Zhang, G; Zhu, G1
Huang, H; Ikejima, T; Jiang, YY; Onodera, S; Tashiro, S; Wang, HJ; Wu, D; Yang, R1
Byun, MW; Cho, BO; Chun, MS; Jeong, IY; Jin, CH; Ko, K; Seo, KI; So, Y1

Other Studies

8 other study(ies) available for silybin and cytochrome c-t

ArticleYear
Involvement of NF-kappaB and caspases in silibinin-induced apoptosis of endothelial cells.
    International journal of molecular medicine, 2004, Volume: 13, Issue:1

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspases; Cytochromes c; DNA; Endothelial Cells; Humans; NF-kappa B; Poly(ADP-ribose) Polymerases; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Silybin; Silymarin

2004
Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release, and caspase activation.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cysteine Proteinase Inhibitors; Cytochromes c; Down-Regulation; Fibroblasts; Keratinocytes; Mice; Phosphorylation; Poly(ADP-ribose) Polymerases; Proteins; Proto-Oncogene Proteins c-bcl-2; Silybin; Silymarin; Tumor Suppressor Protein p53

2005
Silibinin prevents UV-induced HaCaT cell apoptosis partly through inhibition of caspase-8 pathway.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:6

    Topics: Apoptosis; Blotting, Western; Caspase 8; Caspase Inhibitors; Cell Culture Techniques; Cell Line; Cell Survival; Cytochromes c; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; fas Receptor; Fas-Associated Death Domain Protein; Humans; Keratinocytes; Molecular Structure; Signal Transduction; Silybin; Silybum marianum; Silymarin; Ultraviolet Rays

2006
Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.
    Carcinogenesis, 2006, Volume: 27, Issue:11

    Topics: Apoptosis; Benzothiazoles; Caspase 2; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Mitochondria; Models, Biological; Silybin; Silymarin; Toluene; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms

2006
Silibinin protects against isoproterenol-induced rat cardiac myocyte injury through mitochondrial pathway after up-regulation of SIRT1.
    Journal of pharmacological sciences, 2006, Volume: 102, Issue:4

    Topics: Adrenergic beta-Agonists; Aldehydes; Animals; Animals, Newborn; bcl-2-Associated X Protein; bcl-X Protein; Calcium; Cell Survival; Cells, Cultured; Cytochromes c; Dose-Response Relationship, Drug; Isoproterenol; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocytes, Cardiac; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Silybin; Silymarin; Sirtuin 1; Sirtuins; Superoxide Dismutase; Up-Regulation

2006
Chemopreventive and chemotherapeutic effects of intravesical silibinin against bladder cancer by acting on mitochondria.
    Molecular cancer therapeutics, 2011, Volume: 10, Issue:1

    Topics: Administration, Intravesical; Animals; Antioxidants; Apoptosis; Apoptosis Inducing Factor; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Survival; Cytochromes c; Down-Regulation; Female; High-Temperature Requirement A Serine Peptidase 2; Humans; Inhibitor of Apoptosis Proteins; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Mitochondrial Proteins; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Silybin; Silymarin; Survivin; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2011
Interruption of mitochondrial complex IV activity and cytochrome c expression activated O₂·⁻-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways.
    European journal of pharmacology, 2011, Oct-01, Volume: 668, Issue:1-2

    Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Electron Transport Complex IV; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Melanoma; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Protein Kinase C; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction; Silybin; Silymarin; Superoxide Dismutase; Superoxides

2011
Induction of apoptosis by 2,3-dehydrosilybin via a caspase-dependent pathway in human HeLa cells.
    Bioscience, biotechnology, and biochemistry, 2014, Volume: 78, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Caspase Inhibitors; Caspases; Cell Survival; Cytochromes c; Down-Regulation; Enzyme Activation; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Proteolysis; Silybin; Silymarin

2014