Compounds > silybin
Page last updated: 2024-08-23

silybin and cyclin d1

silybin has been researched along with cyclin d1 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agarwal, C; Agarwal, R; Singh, RP; Tyagi, A; Varghese, L1
Agarwal, R; Chittezhath, M; Deep, G; Dwyer-Nield, LD; Kaur, M; Malkinson, AM; Singh, RP1
Agarwal, C; Agarwal, R; Glode, LM; Gu, M; Harrison, G; Raina, K; Singh, RP; Tyagi, A1
Agarwal, R; Gu, M; Singh, RP1
Agarwal, R; Singh, RP; Tyagi, A; Velmurugan, B1
Lin, CJ; Pelletier, J; Sukarieh, R1
Agarwal, R; Kaur, M; Rajamanickam, S; Singh, RP; Velmurugan, B1
Huso, DL; Karim, BO; Liu, G; Rhee, KJ; Zheng, D1
Kassie, F; Luo, X; Molla, K; O Sullivan, G; Qian, X; Song, JM; Teferi, F; Upadhyaya, P1
Asbaghi, N; Chatran, M; Dadashpour, M; Faramarzi, L; Jafari-Gharabaghlou, D; Pilehvar-Soltanahmadi, Y; Rasouli, S; Zarghami, N1
Agarwal, C; Agarwal, R; Deep, G; Jain, A; Orlicky, DJ; Rigby, C1

Other Studies

11 other study(ies) available for silybin and cyclin d1

ArticleYear
Silibinin efficacy against human hepatocellular carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Dec-01, Volume: 11, Issue:23

    Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Cyclin D1; Cyclin D3; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Flow Cytometry; Humans; Liver Neoplasms; Silybin; Silybum marianum; Silymarin; Tumor Cells, Cultured

2005
Effect of silibinin on the growth and progression of primary lung tumors in mice.
    Journal of the National Cancer Institute, 2006, Jun-21, Volume: 98, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Blotting, Western; Carcinogens; Cell Proliferation; Cyclin D1; Cyclooxygenase 2; Disease Models, Animal; Fibroblast Growth Factor 2; Immunohistochemistry; Inflammation; Lung Neoplasms; Mice; Microcirculation; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Silybin; Silymarin; Urethane; Vascular Endothelial Growth Factor A

2006
Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:12 Pt 1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Proliferation; Cyclin D1; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Silybin; Silymarin; Urinary Bladder Neoplasms

2007
Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis.
    Cancer research, 2008, Mar-15, Volume: 68, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Cell Growth Processes; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Enzyme Activation; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Silybin; Silymarin; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2008
Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:5

    Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Carcinoma; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Intestinal Mucosa; Male; Nitric Oxide Synthase Type II; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Silybin; Silymarin

2008
Silibinin inhibits translation initiation: implications for anticancer therapy.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:6

    Topics: Antineoplastic Agents; Antioxidants; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclin D1; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Fluorescent Antibody Technique; Humans; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Protein Biosynthesis; Protein Transport; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Silybin; Silymarin; TOR Serine-Threonine Kinases; Transcription Factors; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2009
Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin.
    Cancer research, 2010, Mar-15, Volume: 70, Issue:6

    Topics: Adenomatous Polyposis Coli; Animals; Antioxidants; Apoptosis; beta Catenin; Cell Growth Processes; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Intestinal Polyps; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Silybin; Silymarin; Transcriptional Activation

2010
Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(-/+) mice.
    BMC cancer, 2013, Mar-27, Volume: 13

    Topics: Adenoma; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoprevention; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Disease Models, Animal; Female; Genes, APC; Humans; Ki-67 Antigen; Mice; Mice, Knockout; Retinoblastoma Protein; Signal Transduction; Silybin; Silymarin

2013
Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.
    Carcinogenesis, 2015, Volume: 36, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclin D1; Cyclin-Dependent Kinases; Cyclooxygenase 2; Drug Combinations; Female; Humans; I-kappa B Proteins; Indoles; Inflammation; Interleukin-6; Lipopolysaccharides; Lung; Lung Neoplasms; Mice; Mice, Inbred A; NF-KappaB Inhibitor alpha; Nitrosamines; Proto-Oncogene Proteins c-akt; Random Allocation; Retinoblastoma Protein; Silybin; Silymarin; Smoke; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha

2015
Synergistic Anti-proliferative Effects of Metformin and Silibinin Combination on T47D Breast Cancer Cells via hTERT and Cyclin D1 Inhibition.
    Drug research, 2018, Volume: 68, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Metformin; Silybin; Telomerase

2018
Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Bone Morphogenetic Protein 2; Carcinoma, Basal Cell; Chemoprevention; Cyclin D1; Disease Models, Animal; DNA Damage; Mast Cells; Mice; Mice, Transgenic; Patched-1 Receptor; Signal Transduction; Silybin; Skin; Skin Neoplasms; Tumor Suppressor Proteins; Ultraviolet Rays

2019