Page last updated: 2024-08-23

silybin and curcumin

silybin has been researched along with curcumin in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.85)29.6817
2010's19 (73.08)24.3611
2020's6 (23.08)2.80

Authors

AuthorsStudies
Kalra, S; Khatik, GL; Kumar, GN; Kumar, R; Narang, R; Nayak, SK; Singh, SK; Sudhakar, K1
Bai, G; Chu, Y; Gu, N; Li, S; Li, T; Li, W; Liu, C; Polachi, N; Sun, H; Wang, X; Wu, J; Zhang, Y; Zhou, S1
Albiñana, CB; Brynda, J; Fanfrlík, J; Flieger, M; Hodek, J; Karlukova, E; Konvalinka, J; Kožíšek, M; Machara, A; Majer, P; Radilová, K; Weber, J; Zima, V1
Hille, R; Pauff, JM1
Danilenko, M; Khanin, M; Pesakhov, S; Studzinski, GP1
Nambiar, D; Singh, RP1
Alibakhshi, A; Barkhordari, A; Esfahlan, RJ; Koshki, KN; Moghaddam, MP; Mollazadeh, M; Nasiri, M; Yamchi, MR; Zarghami, N1
Abhari, A; Akbarzadeh, A; Dariushnejad, H; Nejati-Koshki, K; Pourhasan-Moghaddam, M1
Dai, Y; Meng, J; Wan, X; Yan, S; Zhang, Y1
Ali, SO; Darwish, HA; Ismail, NA2
Kim, MH; Kim, SH; Yang, WM1
Krawinkel, MB; Morlock, GE; Taha, MN1
Akbarzadeh, A; Askari, S; Rahmati-Yamchi, M; Salehi, R; Zarghami, N1
Alderete, JB; Campos, CH; Diáz, C; Guzmán, L; Jiménez, VA; Torres, CC; Vidal, F1
Coppo, L; Gonzalez-Menendez, P; Hevia, D; Holmgren, A; Lu, J; Mayo, JC; Rodriguez-Garcia, A; Sainz, RM1
Alfonso-Moreno, V; López-Serrano, A; Moreno-Osset, E1
Uchaipichat, V1
AbouZid, SF; Ahmed, OM; Ali, TM; Almoiliqy, M; An, S; Anggraeni, AT; Bailón-García, E; Bueno-López, A; Buyze, J; Chen, DQ; Chen, X; Davó-Quiñonero, A; De Weggheleire, A; Ding, Z; El-Kalaawy, AM; Elesawy, BH; Francque, S; Gao, F; Guo, Y; Juan-Juan, J; Li, S; Li, Y; Lin, Y; Liu, X; Liu, Z; Lozano-Castelló, D; Lu, X; Lynen, L; Meng, Q; Peng, J; Ran, Y; Razali, MH; Rodríguez, SL; Shen, MJ; Soedarsono, S; Soeprijanto, B; Su, W; Sun, P; Tang, AL; Thai, S; Tian, G; Topîrceanu, A; van Griensven, J; Wang, H; Wang, Y; Wen, J; Xi, J; Xiong, MC; Yang, S; Yang, X; Yassin, NYS; Ye, L; Yusoff, M; Zhang, GQ; Zhang, Y1
Alam, MJ; Alreshidi, M; Saeed, A; Saeed, M1
Jamshidnia, M; Rafieian-Kopaei, M; Sewell, RDE1
Adem, Ş; Jabeen, F; Rasul, A; Sarfraz, I; Sultana, T1
Dunnick, JK; Kissling, GE; Nyska, A; Peckham, J; Sanders, JM; Singh, B1
Bubley, G; Klempner, SJ1
Gurley, BJ; Markowitz, JS; Munoz, J; Wang, X; Zhu, HJ1
Akram, S; Ashraf, R; Hasany, SM; Huma, R; Mushtaq, M1

Reviews

5 review(s) available for silybin and curcumin

ArticleYear
Recent advancements in mechanistic studies and structure activity relationship of F
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium; Proton-Translocating ATPases; Structure-Activity Relationship

2019
Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer - A comprehensive review.
    European journal of medicinal chemistry, 2016, Nov-10, Volume: 123

    Topics: Animals; Biological Availability; Clinical Trials as Topic; Humans; Liver Neoplasms; Signal Transduction; Silybin; Silymarin

2016
Advances in prostate cancer chemoprevention: a translational perspective.
    Nutrition and cancer, 2013, Volume: 65 Suppl 1

    Topics: Androgen Antagonists; Animals; Anticarcinogenic Agents; Antioxidants; Azasteroids; Carotenoids; Chemoprevention; Clinical Trials as Topic; Curcumin; Disease Models, Animal; Dutasteride; Finasteride; Flavonoids; Genistein; Humans; Lycopene; Male; Phytochemicals; Polyphenols; Prostate; Prostatic Neoplasms; Risk Factors; Selenium; Silybin; Silymarin; Tea; Vitamin E

2013
Mechanisms of action of phytochemicals from medicinal herbs in the treatment of Alzheimer's disease.
    Planta medica, 2014, Volume: 80, Issue:15

    Topics: Alzheimer Disease; Animals; Berberine; Coptis; Curcuma; Curcumin; Ginsenosides; Humans; Isoflavones; Panax notoginseng; Phytochemicals; Plants, Medicinal; Pueraria; Silybin; Silybum marianum; Silymarin

2014
Complementary and alternative medicines in prostate cancer: from bench to bedside?
    The oncologist, 2012, Volume: 17, Issue:6

    Topics: Antioxidants; Beverages; Complementary Therapies; Curcuma; Humans; Lythraceae; Male; Plant Extracts; Prostatic Neoplasms; Resveratrol; Selenium; Silybin; Silymarin; Stilbenes; Tea; Vitamin E; Vitamins

2012

Other Studies

21 other study(ies) available for silybin and curcumin

ArticleYear
Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Antiviral Agents; Crystallography, X-Ray; Drug Evaluation, Preclinical; Endonucleases; Enzyme Assays; Enzyme Inhibitors; Flavonoids; Influenza A virus; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Protein Domains; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins

2020
Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin.
    Journal of natural products, 2009, Volume: 72, Issue:4

    Topics: Animals; Cattle; Curcumin; Luteolin; Molecular Structure; Molybdenum; Purines; Quercetin; Silybin; Silymarin; Superoxides; Xanthine; Xanthine Oxidase

2009
Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells.
    Nutrition and cancer, 2010, Volume: 62, Issue:6

    Topics: Abietanes; Apoptosis; Caspases; Cell Proliferation; Curcumin; Drug Therapy, Combination; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Oligopeptides; Oxidative Stress; Plant Extracts; Silybin; Silymarin

2010
Curcumin and silibinin inhibit telomerase expression in T47D human breast cancer cells.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Breast Neoplasms; Cell Proliferation; Curcumin; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Silybin; Silymarin; Telomerase; Tumor Cells, Cultured

2013
Inhibition of leptin and leptin receptor gene expression by silibinin-curcumin combination.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 14, Issue:11

    Topics: Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Proliferation; Curcumin; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Humans; Leptin; Real-Time Polymerase Chain Reaction; Receptors, Leptin; Signal Transduction; Silybin; Silymarin

2014
Visualization of network target crosstalk optimizes drug synergism in myocardial ischemia.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Celecoxib; Cells, Cultured; Curcumin; Cyclooxygenase 2 Inhibitors; Drug Synergism; Drug Therapy, Combination; Humans; Molecular Targeted Therapy; Myocardial Ischemia; Myocytes, Cardiac; Pyrazoles; Rats; Rats, Sprague-Dawley; Silybin; Silymarin; Sulfonamides

2014
Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats.
    Chemico-biological interactions, 2014, Jun-05, Volume: 216

    Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Curcumin; Gene Expression Regulation; HSP47 Heat-Shock Proteins; Liver Cirrhosis; Male; Matrix Metalloproteinase 2; Oxidative Stress; Rats; Rats, Wistar; Silybin; Silymarin; Thioacetamide; Thioctic Acid; Transforming Growth Factor beta1

2014
High-performance thin-layer chromatography linked with (bio)assays and mass spectrometry - a suited method for discovery and quantification of bioactive components? Exemplarily shown for turmeric and milk thistle extracts.
    Journal of chromatography. A, 2015, May-15, Volume: 1394

    Topics: Aliivibrio fischeri; Anti-Bacterial Agents; Antioxidants; Bacillus subtilis; Biological Assay; Biphenyl Compounds; Chromatography, Thin Layer; Curcuma; Curcumin; Picrates; Plant Extracts; Silybin; Silybum marianum; Silymarin; Spectrometry, Mass, Electrospray Ionization

2015
Curcumin, Silybin Phytosome(®) and α-R-Lipoic Acid Mitigate Chronic Hepatitis in Rat by Inhibiting Oxidative Stress and Inflammatory Cytokines Production.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:5

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Curcumin; Cytokines; Disease Models, Animal; Hepatitis, Chronic; Male; Oxidative Stress; Rats; Rats, Wistar; Silybin; Silymarin; Thioacetamide; Thioctic Acid

2016
The anticancer effects of biodegradable nanomagnetic dual natural components on the leptin gene expression in lung cancer.
    Artificial cells, nanomedicine, and biotechnology, 2016, Volume: 44, Issue:7

    Topics: Cell Line, Tumor; Coated Materials, Biocompatible; Curcumin; Gene Expression Regulation, Neoplastic; Humans; Leptin; Lung Neoplasms; Magnetite Nanoparticles; Neoplasm Proteins; Polyesters; Polyethylene Glycols; Silybin; Silymarin

2016
PAMAM-grafted TiO2 nanotubes as novel versatile materials for drug delivery applications.
    Materials science & engineering. C, Materials for biological applications, 2016, Aug-01, Volume: 65

    Topics: Cell Survival; Curcumin; Dendrimers; Drug Carriers; Drug Liberation; HeLa Cells; Humans; Methotrexate; Microscopy, Electron, Transmission; Nanotubes; Pharmaceutical Preparations; Silybin; Silymarin; Spectroscopy, Fourier Transform Infrared; Titanium

2016
Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells.
    Redox biology, 2017, Volume: 12

    Topics: Apoptosis; Carrier Proteins; Cell Line, Tumor; Cell Survival; Curcumin; Gene Expression Regulation, Neoplastic; Humans; Male; Melatonin; Prostatic Neoplasms; Reactive Oxygen Species; Resveratrol; Silybin; Silymarin; Stilbenes; Thioredoxins

2017
Chemoprevention of polyp recurrence with curcumin followed by silibinin in a case of multiple colorectal adenomas.
    Revista espanola de enfermedades digestivas, 2017, Volume: 109, Issue:12

    Topics: Antineoplastic Agents; Chemoprevention; Colorectal Neoplasms; Curcumin; Drug Therapy, Combination; Humans; Intestinal Polyps; Male; Middle Aged; Recurrence; Silybin; Silymarin

2017
In vitro inhibitory effects of major bioactive constituents of Andrographis paniculata, Curcuma longa and Silybum marianum on human liver microsomal morphine glucuronidation: A prediction of potential herb-drug interactions arising from andrographolide, c
    Drug metabolism and pharmacokinetics, 2018, Volume: 33, Issue:1

    Topics: Andrographis; Animals; Cattle; Curcuma; Curcumin; Diterpenes; Forecasting; Glucuronides; Herb-Drug Interactions; Humans; Microsomes, Liver; Morphine; Protein Binding; Silybin; Silybum marianum; Silymarin

2018
    Procedia computer science, 2021, Volume: 192

    Topics: Acute Lung Injury; Adherens Junctions; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antigens, CD; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; beta Catenin; Brain Ischemia; Cadherins; Carcinogenesis; Catalysis; Cell Line; Cells, Cultured; Curcuma; Curcumin; Dioxoles; Disease Models, Animal; Endothelial Cells; Epithelial Cells; Heme Oxygenase (Decyclizing); Humans; Inflammasomes; Intestinal Diseases; Intestinal Mucosa; Ischemic Stroke; Kidney Neoplasms; Lignans; Lung; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; NAD(P)H Dehydrogenase (Quinone); Nanostructures; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phytotherapy; Plant Extracts; Pneumonia; PPAR gamma; Proto-Oncogene Proteins c-akt; Pyroptosis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Sepsis; Sesamum; Signal Transduction; Silybin; Silybum marianum; Silymarin; Sirtuin 3; Titanium; Transfection; Treatment Outcome; White Matter

2021
Computational hunting of natural active compounds as an alternative for Remdesivir to target RNA-dependent polymerase.
    Cellular and molecular biology (Noisy-le-Grand, France), 2021, Jan-31, Volume: 67, Issue:1

    Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Biological Products; Catalytic Domain; Coronavirus RNA-Dependent RNA Polymerase; COVID-19; Curcumin; Databases, Protein; Drug Discovery; Drug Evaluation, Preclinical; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Phytochemicals; Protein Binding; SARS-CoV-2; Silybin

2021
An Update on Promising Agents against COVID-19: Secondary Metabolites and Mechanistic Aspects.
    Current pharmaceutical design, 2022, Volume: 28, Issue:29

    Topics: Animals; Antiviral Agents; COVID-19 Drug Treatment; Curcumin; Humans; Kaempferols; Peptide Hydrolases; SARS-CoV-2; Silybin; Spike Glycoprotein, Coronavirus

2022
Identification of Natural Compounds as Inhibitors of Pyruvate Kinase M2 for Cancer Treatment.
    Molecules (Basel, Switzerland), 2022, Oct-21, Volume: 27, Issue:20

    Topics: Cell Line, Tumor; Curcumin; Ellagic Acid; Glycolysis; Humans; Leukemia, Myeloid, Acute; Pyruvate Kinase; Resveratrol; Silybin

2022
Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle.
    Toxicologic pathology, 2011, Volume: 39, Issue:2

    Topics: Animals; Berberine; Body Weight; Carcinogens; Female; Flavonolignans; Hydrastis; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Plant Preparations; Plant Roots; Rats; Rats, Inbred F344; Silybin; Silybum marianum; Silymarin; Topoisomerase Inhibitors; Toxicity Tests, Chronic

2011
An ex vivo approach to botanical-drug interactions: a proof of concept study.
    Journal of ethnopharmacology, 2015, Apr-02, Volume: 163

    Topics: Adult; Benzylisoquinolines; Berberine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Female; Herb-Drug Interactions; Humans; Hydrastis; Male; Microsomes, Liver; Midazolam; Plant Extracts; Silybin; Silybum marianum; Silymarin; Tolbutamide; Young Adult

2015
Maceration-Mediated Liquid-Liquid Extraction and Reverse-Phase High-Performance Liquid Chromatography-Based Pragmatic Analysis of Silybins.
    Journal of chromatographic science, 2020, Aug-21, Volume: 58, Issue:8

    Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Curcuma; Limit of Detection; Linear Models; Liquid-Liquid Extraction; Plant Extracts; Reproducibility of Results; Silybin

2020