silybin has been researched along with acetylcysteine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 14 (70.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| El-Bahay, C; Hanelt, S; Kahl, R; Lewerenz, V; Nastevska, C; Röhrdanz, E | 1 |
| Mahendran, R; Pook, SH; Toh, CK | 1 |
| Blonk, MI; Ennecker-Jans, SA; van Daele, PL; van Laar, JA; Varin, DS | 1 |
| Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC | 1 |
| Galanopoulou, P; Giannioti, K; Liapi, C; Mikros, E; Papalois, A; Theocharis, S; Zira, A | 1 |
| Dziegiel, P; Gomułkiewicz, A; Magdalan, J; Ostrowska, A; Patrzałek, D; Piotrowska, A; Podhorska-Okołów, M; Szelag, A | 1 |
| Doré, JC; Fons, F; Michelot, D; Poucheret, P; Rapior, S | 1 |
| Dziegięl, P; Gomułkiewicz, A; Magdalan, J; Piotrowska, A; Sozański, T; Szeląg, A | 1 |
| Duan, W; Ikejima, T; Jin, X; Li, Q; Onodera, S; Tashiro, S | 1 |
| Chen, S; Fan, S; Ikejima, T; Li, L; Onodera, S; Qi, M; Tashiro, S; Yu, Y | 1 |
| Nawrocka, K; Popiołek, A; Łukasik-Głebocka, M | 1 |
| Cho, HJ; Choi, KU; Kim, KH; Kim, YK; Moon, SH; Park, DY; Song, YJ; Suh, DS; Yoon, MS | 1 |
| Brinkert, F; Fischer, L; Ganschow, R; Grabhorn, E; Herden, U; Hillebrand, G; Nielsen, D | 1 |
| Onodera, M | 1 |
| Liu, X; Wang, Q; Xu, R; Yang, J; Zang, M; Zhang, J | 1 |
| Hauffe, T; Kupferschmidt, H; Mayer, F | 1 |
| Andrade, S; Baptista, P; Carneiro, AC; Carvalho, F; Conceição, F; Costa, AE; Costa, VM; de Lourdes Bastos, M; de Pinho, PG; Garcia, J; Paiva, JA | 1 |
| Fix, OK; Hameed, B; Karvellas, CJ; Lee, WM; Leung, AA; McGuire, BM; Schilsky, ML; Stravitz, RT; Tillman, H | 1 |
| Dekkers, BGJ; Stam, J; Tan, JL; Touw, DJ; van den Berg, AP; van Rheenen, PF | 1 |
3 review(s) available for silybin and acetylcysteine
| Article | Year |
|---|---|
[Clinical toxicology of mushroom poisoning. Amanita virosa].
Topics: Acetylcysteine; Amanita; Amanitins; Bile; Blood Component Removal; Charcoal; Chromatography, High Pressure Liquid; Drainage; Gastric Lavage; Humans; Japan; Laxatives; Liver Transplantation; Mushroom Poisoning; Penicillin G; Silybin; Silymarin | 2013 |
[Poisoning with Amanita mushrooms].
Topics: Acetylcysteine; Adult; Amanita; Amanitins; Cause of Death; Combined Modality Therapy; Critical Care; Diagnosis, Differential; Hepatic Encephalopathy; Humans; Liver Function Tests; Liver Transplantation; Male; Mushroom Poisoning; Prognosis; Silybin; Silymarin | 2013 |
Amanitin intoxication: effects of therapies on clinical outcomes - a review of 40 years of reported cases.
Topics: Acetylcysteine; Alanine Transaminase; Amanita; Amanitins; Humans; Mushroom Poisoning; Penicillin G; Silybin | 2022 |
17 other study(ies) available for silybin and acetylcysteine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Antioxidants protect primary rat hepatocyte cultures against acetaminophen-induced DNA strand breaks but not against acetaminophen-induced cytotoxicity.
Topics: Acetaminophen; Acetylcysteine; alpha-Tocopherol; Analgesics, Non-Narcotic; Animals; Antioxidants; Blotting, Northern; Cell Death; Chemical and Drug Induced Liver Injury; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Formazans; Hepatocytes; Lipid Peroxides; Liver Diseases; Male; Neutral Red; Rats; Rats, Wistar; RNA; Silybin; Silymarin; Tetrazolium Salts | 2003 |
Combination of thiol antioxidant Silibinin with Brostallicin is associated with increase in the anti-apoptotic protein Bcl-2 and decrease in caspase 3 activity.
Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Down-Regulation; Drug Antagonism; Drug Screening Assays, Antitumor; Enzyme Activation; Guanidines; Humans; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Signal Transduction; Silybin; Silymarin; Sulfhydryl Compounds; Up-Regulation | 2006 |
[Amatoxin poisoning due to soup from personally picked deathcap mushrooms (Amanita phalloides)].
Topics: Acetylcysteine; Amanita; Amanitins; Antioxidants; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Mushroom Poisoning; Penicillin G; Silybin; Silymarin; Treatment Outcome; Urinalysis | 2007 |
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cimetidine; Disease Models, Animal; Male; Mice; Mushroom Poisoning; Penicillin G; Random Allocation; Silybin; Silymarin; Thioctic Acid | 2007 |
Acute liver acetaminophen toxicity in rabbits and the use of antidotes: a metabonomic approach in serum.
Topics: Acetaminophen; Acetylcysteine; Acute Disease; Alanine Transaminase; Animals; Antidotes; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cimetidine; Disease Models, Animal; Liver; Magnetic Resonance Spectroscopy; Male; Rabbits; Silybin; Silymarin | 2009 |
Benzylpenicillin, acetylcysteine and silibinin as antidotes in human hepatocytes intoxicated with alpha-amanitin.
Topics: Acetylcysteine; Alpha-Amanitin; Antidotes; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Hepatocytes; Humans; Penicillin G; Poisons; Silybin; Silymarin | 2010 |
Amatoxin poisoning treatment decision-making: pharmaco-therapeutic clinical strategy assessment using multidimensional multivariate statistic analysis.
Topics: Acetylcysteine; Algorithms; Amanitins; Anti-Bacterial Agents; Antioxidants; Ceftazidime; Databases, Factual; Decision Making; Decision Theory; Factor Analysis, Statistical; Humans; Multivariate Analysis; Mushroom Poisoning; Retrospective Studies; Silybin; Silymarin; Survival; Survival Rate | 2010 |
Influence of commonly used clinical antidotes on antioxidant systems in human hepatocyte culture intoxicated with alpha-amanitin.
Topics: Acetylcysteine; Alpha-Amanitin; Amanita; Antidotes; Antioxidants; Catalase; Cells, Cultured; Hepatocytes; Humans; Lipid Peroxidation; Mushroom Poisoning; Nucleic Acid Synthesis Inhibitors; Oxidants; Penicillin G; Silybin; Silymarin; Superoxide Dismutase | 2011 |
Silibinin induced autophagic and apoptotic cell death in HT1080 cells through a reactive oxygen species pathway.
Topics: Acetylcysteine; Adenine; Antioxidants; Apoptosis; Autophagy; Cell Line; Culture Media, Serum-Free; Drug Interactions; Humans; Hydrogen Peroxide; Reactive Oxygen Species; Signal Transduction; Silybin; Silymarin | 2010 |
Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells.
Topics: Acetylcysteine; Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase 3; Cell Survival; Glutathione; HeLa Cells; Humans; Hydroxyl Radical; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Reactive Nitrogen Species; Reactive Oxygen Species; Silybin; Silymarin | 2011 |
[Some issues of death cap (Amanita phalloides) poisoning based on cases treated in Poznan Department of Toxicology in 2010].
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Amanita; Antioxidants; Drug Administration Schedule; Expectorants; Female; Humans; Male; Middle Aged; Mushroom Poisoning; Poland; Retrospective Studies; Seasons; Silybin; Silymarin; Young Adult | 2011 |
Silibinin inhibits tumor growth through downregulation of extracellular signal-regulated kinase and Akt in vitro and in vivo in human ovarian cancer cells.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Caspase 3; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Ki-67 Antigen; Mice; Mice, Inbred BALB C; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Silybin; Silymarin | 2013 |
Successful outcome of severe Amanita phalloides poisoning in children.
Topics: Acetylcysteine; Amanita; Antioxidants; Child; Child, Preschool; Critical Care; Female; Follow-Up Studies; Humans; Infant; Liver Failure, Acute; Liver Transplantation; Male; Mushroom Poisoning; Prognosis; Retrospective Studies; Silybin; Silymarin; Treatment Outcome | 2013 |
Changes in pharmacokinetic profiles of acetaminophen and its glucuronide after pretreatment with combinations of N-acetylcysteine and either glycyrrhizin, silibinin or spironolactone in rat.
Topics: Acetaminophen; Acetylcysteine; Animals; Glycyrrhizic Acid; Hepatobiliary Elimination; Injections, Intraperitoneal; Liver; Male; Rats, Sprague-Dawley; Silybin; Silymarin; Spironolactone; Time Factors | 2014 |
Co-ingestion of amatoxins and isoxazoles-containing mushrooms and successful treatment: A case report.
Topics: Acetylcysteine; Agaricales; Aged; Alpha-Amanitin; Amanita; Amanitins; Charcoal; Female; Gas Chromatography-Mass Spectrometry; Humans; Isoxazoles; Mushroom Poisoning; Silybin; Silymarin | 2015 |
Acute liver injury and acute liver failure from mushroom poisoning in North America.
Topics: Acetylcysteine; Adult; Amanitins; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Humans; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Mushroom Poisoning; North America; Penicillins; Registries; Silybin; Silymarin | 2016 |