silybin has been researched along with 2,3-dehydrosilybin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barron, D; Comte, G; Conseil, G; Di Pietro, A; El Kirat, K; Maitrejean, M | 1 |
| Feng, YB; Gong, JX; Huang, KX; Li, HB; Li, XK; Qu, J; Spencer, S; Tao, QF; Wang, F; Wu, XM; Wu, YH; Yang, LX; Zeng, S; Zhao, Y | 1 |
| De Napoli, L; Di Fabio, G; Petito, V; Previtera, L; Sgambato, A; Zarrelli, A | 1 |
| Chen, G; Chen, QH; Huang, M; Lee, T; Vue, B; Wang, G; Zhang, Q; Zhang, S; Zhang, X; Zheng, S | 1 |
| Bartůněk, P; Bednárová, L; Biedermann, D; Buchta, M; Cvačka, J; Holečková, V; Křen, V; Křenková, A; Kuzma, M; Peikerová, Ž; Sedlák, D; Škuta, C; Valentová, K | 1 |
| Dvorák, Z; Ulrichová, J; Vrzal, R | 1 |
| Psotová, J; Svobodová, A; Walterová, D | 1 |
| Chamulitrat, W; Stremmel, W; Thongphasuk, P | 1 |
| Chu, C; Gao, X; Tong, S; Wang, L; Wei, Y; Xu, X; Yu, J | 1 |
| Digel, M; Füllekrug, J; Küch, EM; Stremmel, W; Zhan, T | 1 |
| Agarwal, C; Agarwal, R; Biedermann, D; Deep, G; Gažák, R; Křen, V; Wadhwa, R | 1 |
| De Napoli, L; Di Fabio, G; Di Marino, C; Romanucci, V; Zarrelli, A | 1 |
| Křen, V; Kuzma, M; Marhol, P; Ulrichová, J; Vacek, J; Valentová, K; Vavříková, E | 1 |
| Martínez, A; Reina, M | 1 |
| Biedermann, D; Chambers, CS; Cvačka, J; Gažák, R; Karas, D; Křen, V; Křenková, A; Kuzma, M; Oborná, I; Pivodová, V; Ulrichová, J; Valentová, K | 1 |
| Biedermann, D; Křen, V; Papoušková, B; Roubalová, L; Ulrichová, J; Vacek, J; Valentová, K; Vrba, J; Zatloukalová, M | 1 |
| Alunda, JM; Biedermann, D; Corral, MJ; Jiménez-Antón, MD; Olías-Molero, AI | 1 |
| Benada, O; Biedermann, D; Hrčková, G; Kofroňová, O; Kubašková, TM; Tumová, L | 1 |
18 other study(ies) available for silybin and 2,3-dehydrosilybin
| Article | Year |
|---|---|
The flavanolignan silybin and its hemisynthetic derivatives, a novel series of potential modulators of P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Flavonoids; Flavonols; Magnetic Resonance Spectroscopy; Molecular Structure; Plants, Medicinal; Protein Binding; Quercetin; Silybum marianum; Silymarin | 2000 |
Design, synthesis, and examination of neuron protective properties of alkenylated and amidated dehydro-silybin derivatives.
Topics: Alkenes; Alzheimer Disease; Amides; Animals; Drug Design; Free Radical Scavengers; Humans; Iron Chelating Agents; Lipid Peroxidation; Liver; Male; Models, Molecular; Molecular Conformation; Neurons; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Rats; Silymarin; Structure-Activity Relationship; Xanthine Oxidase | 2009 |
New C-23 modified of silybin and 2,3-dehydrosilybin: synthesis and preliminary evaluation of antioxidant properties.
Topics: Animals; Antioxidants; Cell Line; Rats; Silybin; Silymarin; Stereoisomerism | 2011 |
3-O-Alkyl-2,3-dehydrosilibinins: Two synthetic approaches and in vitro effects toward prostate cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Prostatic Neoplasms; Silymarin; Structure-Activity Relationship | 2016 |
Silychristin: Skeletal Alterations and Biological Activities.
Topics: Antioxidants; Fruit; Humans; Molecular Structure; Plant Extracts; Plant Roots; Silybin; Silybum marianum; Silymarin | 2016 |
Silybin and dehydrosilybin inhibit cytochrome P450 1A1 catalytic activity: a study in human keratinocytes and human hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Dioxins; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Keratinocytes; Liver Neoplasms; Molecular Structure; Silybin; Silymarin; Time Factors | 2006 |
Influence of silymarin and its flavonolignans on H(2)O(2)-induced oxidative stress in human keratinocytes and mouse fibroblasts.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Flavonolignans; Flavonols; Humans; Hydrogen Peroxide; Keratinocytes; Mice; Mice, Inbred BALB C; Oxidants; Oxidative Stress; Phytotherapy; Plant Extracts; Protective Agents; Quercetin; Silybin; Silymarin | 2006 |
2,3-dehydrosilybin is a better DNA topoisomerase I inhibitor than its parental silybin.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Data Interpretation, Statistical; DNA Topoisomerases, Type I; Humans; Silybin; Silymarin; Time Factors; Topoisomerase I Inhibitors; Tumor Necrosis Factor-alpha | 2009 |
Preparation and effects of 2,3-dehydrosilymarin, a promising and potent antioxidant and free radical scavenger.
Topics: Animals; Carbon Tetrachloride; Chromatography, High Pressure Liquid; Free Radical Scavengers; Free Radicals; Liver; Male; Mass Spectrometry; Mice; Oxidation-Reduction; Silybin; Silymarin; Solubility | 2011 |
Silybin and dehydrosilybin decrease glucose uptake by inhibiting GLUT proteins.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Deoxyglucose; Enzyme Assays; Glucose; Glucose Transporter Type 4; GTPase-Activating Proteins; Hexokinase; Humans; Hypoglycemic Agents; Insulin; Mice; Oncogene Protein v-akt; Phosphorylation; Protein Transport; Recombinant Fusion Proteins; Silybin; Silymarin | 2011 |
Anti-cancer efficacy of silybin derivatives -- a structure-activity relationship.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; HCT116 Cells; Humans; Male; Molecular Structure; Silybin; Silymarin; Structure-Activity Relationship | 2013 |
A rapid and simple chromatographic separation of diastereomers of silibinin and their oxidation to produce 2,3-dehydrosilybin enantiomers in an optically pure form.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Oxidation-Reduction; Silybin; Silybum marianum; Silymarin; Stereoisomerism | 2013 |
Chemo-enzymatic synthesis of silybin and 2,3-dehydrosilybin dimers.
Topics: Animals; Biocatalysis; Biphenyl Compounds; Cell Survival; Dimerization; Fibroblasts; Free Radical Scavengers; Fungal Proteins; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Keratinocytes; Lipase; Lipid Peroxidation; Mice; Microsomes, Liver; Oxidation-Reduction; Picrates; Rats; Silybin; Silymarin | 2014 |
Silybin and 2,3-Dehydrosilybin Flavonolignans as Free Radical Scavengers.
Topics: Computer Simulation; Electrons; Flavonolignans; Free Radical Scavengers; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Chemical; Molecular Structure; Oxidation-Reduction; Protons; Silybin; Silymarin; Spectrum Analysis, Raman | 2015 |
Effects of 2,3-Dehydrosilybin and Its Galloyl Ester and Methyl Ether Derivatives on Human Umbilical Vein Endothelial Cells.
Topics: Cell Survival; Free Radical Scavengers; Gallic Acid; Human Umbilical Vein Endothelial Cells; Humans; Methyl Ethers; Molecular Structure; Silybin; Silymarin; Structure-Activity Relationship | 2016 |
Metabolism of flavonolignans in human hepatocytes.
Topics: Adult; Aged; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Female; Flavonolignans; Hepatocytes; Humans; Male; Middle Aged; Silybin; Silymarin; Tandem Mass Spectrometry | 2018 |
In-Vitro Activity of Silybin and Related Flavonolignans against
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dogs; Humans; Leishmania donovani; Leishmania infantum; Leishmaniasis, Visceral; Silybin; Silymarin | 2018 |
Differential Effects of the Flavonolignans Silybin, Silychristin and 2,3-Dehydrosilybin on
Topics: Animals; Antioxidants; Hypoxia; In Vitro Techniques; Larva; Mesocestoides; Protective Agents; Silybin; Silymarin | 2018 |