silicon has been researched along with pancratistatin* in 1 studies
1 other study(ies) available for silicon and pancratistatin
Article | Year |
---|---|
β-Silyl styrene as a dienophile in the cycloaddition with 3,5-dibromo-2-pyrone for the total synthesis of (±)-pancratistatin.
A new synthetic route to (±)-pancratistatin was devised utilizing β-silyl styrene as a dienophile in the cycloaddition with 3,5-dibromo-2-pyrone. The TMS group incorporated in the cycloadduct permitted a facile elimination process for the eventual installation of the C(1)-OH function. Subsequent transformations including Curtius rearrangement and Bischler-Napieralski reactions completed the total synthesis of (±)-pancratistatin. Topics: Amaryllidaceae Alkaloids; Cyclization; Isoquinolines; Molecular Structure; Pyrones; Silicon; Styrene | 2011 |